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OPENSEQ.org

THIH - THIS
UniProt: P30140 - O32583
Length: 443
Sequences: 276
Seq/Len: 0.63
I_Prob: 0.09

THIH - 2-iminoacetate synthase
Paralog alert: 0.60 [within 20: 0.11] - ratio of genomes with paralogs
Cluster includes: BIOB THIH
THIS - Sulfur carrier protein ThiS
Paralog alert: 0.02 [within 20: 0.00] - ratio of genomes with paralogs
Cluster includes: THIS
GREMLIN Results (Scaled_score > 1):

Legend: The darker and larger the blue dots, the higher strength in coevolution.

Residue pairs sorted by strength in coevolution signal:
i j Scaled Score I_Prob
322_S 46_W 1.83 0.09
316_N 34_L 1.28 0.02
213_G 33_A 1.25 0.02
73_V 3_I 1.22 0.02
212_L 35_A 1.16 0.01
178_V 33_A 1.15 0.01
356_A 15_G 1.15 0.01
132_H 64_A 1.15 0.01
278_R 39_Q 1.11 0.01
221_G 60_F 1.10 0.01
84_L 60_F 1.10 0.01
329_Y 46_W 1.09 0.01
354_L 14_A 1.06 0.01
122_F 12_C 1.06 0.01
254_R 60_F 1.05 0.01
84_L 64_A 1.05 0.01
27_D 3_I 1.03 0.01
240_A 57_I 1.02 0.01
160_Q 64_A 1.02 0.01
213_G 61_Q 1.02 0.01
326_P 62_V 1.00 0.01
128_V 62_V 1.00 0.01
179_M 64_A 0.97 0.01
295_E 35_A 0.96 0.01
56_Q 13_A 0.96 0.01
304_P 5_F 0.95 0.01
193_H 60_F 0.95 0.01
303_S 3_I 0.93 0.01
155_L 9_A 0.93 0.01
176_D 63_I 0.92 0.01
73_V 7_D 0.92 0.01
347_P 1_M 0.92 0.01
40_D 8_Q 0.92 0.01
329_Y 35_A 0.91 0.01
257_V 8_Q 0.91 0.01
212_L 62_V 0.91 0.01
124_H 64_A 0.90 0.01
127_L 54_G 0.89 0.01
235_D 33_A 0.89 0.01
268_G 18_V 0.88 0.01
317_N 62_V 0.87 0.01
296_L 3_I 0.86 0.01
201_D 12_C 0.86 0.01
254_R 64_A 0.86 0.01
179_M 62_V 0.86 0.01
219_K 35_A 0.85 0.01
311_I 16_Q 0.85 0.01
29_E 5_F 0.85 0.00
186_H 13_A 0.85 0.00
321_F 1_M 0.85 0.00
213_G 59_L 0.84 0.00
63_R 1_M 0.84 0.00
254_R 63_I 0.84 0.00
148_L 61_Q 0.84 0.00
240_A 63_I 0.84 0.00
248_Q 18_V 0.84 0.00
230_D 36_I 0.83 0.00
353_A 21_L 0.83 0.00
363_W 57_I 0.83 0.00
24_T 48_Q 0.83 0.00
218_D 64_A 0.83 0.00
291_A 60_F 0.82 0.00
341_P 1_M 0.82 0.00
240_A 42_P 0.82 0.00
112_R 43_R 0.82 0.00
128_V 64_A 0.81 0.00
254_R 62_V 0.81 0.00
226_I 63_I 0.81 0.00
112_R 5_F 0.80 0.00
217_I 40_I 0.80 0.00
251_W 35_A 0.80 0.00
325_Q 64_A 0.80 0.00
193_H 62_V 0.80 0.00
120_M 58_L 0.79 0.00
207_E 26_D 0.79 0.00
293_E 57_I 0.79 0.00
73_V 63_I 0.79 0.00
255_Y 62_V 0.79 0.00
278_R 59_L 0.79 0.00
291_A 64_A 0.79 0.00
25_A 57_I 0.79 0.00
99_R 27_Q 0.79 0.00
354_L 34_L 0.78 0.00
Legend: The i (protein A) and j (protein B) are positions as given in the UniProt sequences. The value of the raw score is the function of the learning procedure, L2 normalization and APC (entropic) correction.

Scaled Score = raw_score/average(raw_scores)
I_Prob = P(contact | scaled_score, seq/len, top_inter_score)

Text file of predictions
(includes both intra and inter preds)

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