| UniProt: | Q46866 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG13024 | ||
| Length: | 160 (156) | ||
| Sequences: | 1334 | ||
| Seq/Len: | 8.55 |
| YGIV
Paralog alert: 0.52 [within 20: 0.02] - ratio of genomes with paralogs Cluster includes: SBMC YGIV |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 129_K | 160_A | 3.175 | 1.00 | |
| 17_P | 91_N | 2.721 | 1.00 | |
| 15_S | 93_E | 2.519 | 1.00 | |
| 104_H | 114_T | 2.518 | 1.00 | |
| 15_S | 96_G | 2.413 | 1.00 | |
| 103_R | 154_D | 2.385 | 1.00 | |
| 18_V | 75_C | 2.037 | 1.00 | |
| 56_G | 72_F | 2.025 | 1.00 | |
| 16_I | 94_L | 1.981 | 1.00 | |
| 60_D | 71_R | 1.951 | 1.00 | |
| 100_A | 122_W | 1.904 | 1.00 | |
| 22_P | 71_R | 1.871 | 1.00 | |
| 123_L | 126_S | 1.867 | 1.00 | |
| 122_W | 126_S | 1.867 | 1.00 | |
| 12_D | 98_R | 1.852 | 1.00 | |
| 98_R | 128_E | 1.826 | 1.00 | |
| 97_G | 131_R | 1.767 | 1.00 | |
| 11_I | 101_V | 1.755 | 1.00 | |
| 56_G | 74_I | 1.747 | 1.00 | |
| 115_V | 155_V | 1.705 | 1.00 | |
| 58_A | 72_F | 1.67 | 1.00 | |
| 10_I | 100_A | 1.64 | 1.00 | |
| 21_L | 33_S | 1.615 | 1.00 | |
| 105_V | 152_E | 1.593 | 1.00 | |
| 102_A | 118_I | 1.592 | 1.00 | |
| 9_N | 101_V | 1.592 | 1.00 | |
| 138_H | 154_D | 1.504 | 1.00 | |
| 59_W | 73_D | 1.464 | 0.99 | |
| 133_A | 158_P | 1.437 | 0.99 | |
| 128_E | 159_L | 1.382 | 0.99 | |
| 11_I | 156_Y | 1.374 | 0.99 | |
| 99_Y | 136_L | 1.358 | 0.99 | |
| 33_S | 37_F | 1.355 | 0.99 | |
| 17_P | 93_E | 1.355 | 0.99 | |
| 40_W | 89_V | 1.342 | 0.99 | |
| 117_G | 121_H | 1.33 | 0.99 | |
| 34_V | 74_I | 1.317 | 0.99 | |
| 33_S | 74_I | 1.316 | 0.99 | |
| 19_A | 89_V | 1.312 | 0.99 | |
| 12_D | 96_G | 1.3 | 0.99 | |
| 141_N | 151_L | 1.285 | 0.98 | |
| 8_V | 122_W | 1.282 | 0.98 | |
| 136_L | 156_Y | 1.269 | 0.98 | |
| 24_R | 69_A | 1.258 | 0.98 | |
| 113_H | 155_V | 1.256 | 0.98 | |
| 22_P | 73_D | 1.239 | 0.98 | |
| 95_T | 133_A | 1.238 | 0.98 | |
| 8_V | 102_A | 1.224 | 0.98 | |
| 73_D | 92_G | 1.223 | 0.98 | |
| 20_M | 73_D | 1.21 | 0.97 | |
| 19_A | 78_V | 1.201 | 0.97 | |
| 58_A | 70_F | 1.2 | 0.97 | |
| 53_Q | 138_H | 1.191 | 0.97 | |
| 146_V | 153_T | 1.191 | 0.97 | |
| 32_Y | 35_A | 1.189 | 0.97 | |
| 118_I | 157_V | 1.174 | 0.97 | |
| 37_F | 55_F | 1.162 | 0.96 | |
| 114_T | 118_I | 1.154 | 0.96 | |
| 103_R | 152_E | 1.15 | 0.96 | |
| 97_G | 133_A | 1.148 | 0.96 | |
| 56_G | 139_Y | 1.142 | 0.96 | |
| 8_V | 117_G | 1.132 | 0.96 | |
| 13_F | 136_L | 1.11 | 0.95 | |
| 13_F | 16_I | 1.109 | 0.95 | |
| 58_A | 137_F | 1.105 | 0.95 | |
| 62_P | 65_T | 1.101 | 0.95 | |
| 20_M | 92_G | 1.099 | 0.95 | |
| 104_H | 115_V | 1.093 | 0.94 | |
| 123_L | 130_M | 1.083 | 0.94 | |
| 148_E | 151_L | 1.068 | 0.93 | |
| 115_V | 135_I | 1.063 | 0.93 | |
| 85_N | 88_G | 1.058 | 0.93 | |
| 74_I | 99_Y | 1.05 | 0.93 | |
| 101_V | 156_Y | 1.049 | 0.93 | |
| 119_I | 130_M | 1.022 | 0.91 | |
| 22_P | 90_S | 1.021 | 0.91 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 1jyhA | 1 | 0.9375 | 100 | 0.222 | Contact Map | 0.702 |
| 3lurA | 3 | 0.925 | 100 | 0.241 | Contact Map | 0.767 |
| 3gk6A | 1 | 0.9062 | 100 | 0.248 | Contact Map | 0.702 |
| 3b49A | 1 | 0.9938 | 99.9 | 0.301 | Contact Map | 0.723 |
| 1d5yA | 4 | 0.9563 | 99.9 | 0.312 | Contact Map | 0.709 |
| 3e0hA | 1 | 0.9437 | 99.9 | 0.331 | Contact Map | 0.708 |
| 1r8eA | 1 | 0.9563 | 99.9 | 0.361 | Contact Map | 0.628 |
| 4b0yA | 1 | 0.95 | 88 | 0.863 | Contact Map | 0.628 |
| 3r8jA | 2 | 0.95 | 86.6 | 0.866 | Contact Map | 0.671 |
| 2govA | 1 | 0.95 | 81.9 | 0.873 | Contact Map | 0.519 |
Sequence Conservation (Image Generated using WebLogo v3)