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OPENSEQ.org
GTRB - Bactoprenol glucosyl transferase homolog from prophage CPS-53
UniProt: P77293 Sequence
 Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG14132
Length: 306 (305)
Sequences: 2839
Seq/Len: 9.31
GTRB
Paralog alert: 0.40 [within 20: 0.04] - ratio of genomes with paralogs
Cluster includes: ARNC GTRB
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
40_N 65_S 4.89 1.00
13_E 46_A 4.813 1.00
51_I 63_P 3.778 1.00
108_K 111_A 3.633 1.00
46_A 49_S 3.582 1.00
113_A 189_D 3.484 1.00
52_N 303_R 3.372 1.00
161_R 165_E 3.011 1.00
22_T 100_E 2.873 1.00
4_S 85_G 2.717 1.00
20_Y 58_D 2.588 1.00
9_V 47_T 2.524 1.00
48_E 63_P 2.519 1.00
108_K 189_D 2.496 1.00
4_S 35_E 2.418 1.00
48_E 65_S 2.359 1.00
20_Y 54_L 2.321 1.00
18_I 21_K 2.319 1.00
104_H 107_E 2.306 1.00
121_S 194_V 2.22 1.00
97_D 195_R 2.181 1.00
87_A 109_W 2.134 1.00
240_A 270_F 2.074 1.00
119_K 192_E 2.073 1.00
65_S 302_K 2.055 1.00
109_W 160_S 2.027 1.00
35_E 85_G 2.009 1.00
88_I 164_V 2.004 1.00
4_S 37_V 1.993 1.00
279_I 282_L 1.985 1.00
20_Y 38_F 1.973 1.00
107_E 110_Q 1.962 1.00
66_F 78_A 1.954 1.00
38_F 51_I 1.925 1.00
286_I 289_T 1.924 1.00
114_D 160_S 1.906 1.00
7_V 19_F 1.895 1.00
89_I 102_I 1.85 1.00
46_A 50_I 1.85 1.00
87_A 158_L 1.837 1.00
17_P 50_I 1.827 1.00
20_Y 61_V 1.805 1.00
233_G 273_G 1.78 1.00
11_N 44_K 1.701 1.00
22_T 196_A 1.665 1.00
50_I 53_A 1.658 1.00
17_P 21_K 1.646 1.00
81_D 168_K 1.61 1.00
166_N 186_G 1.595 1.00
109_W 158_L 1.581 1.00
64_L 301_I 1.575 1.00
17_P 53_A 1.573 1.00
32_Y 110_Q 1.571 1.00
89_I 158_L 1.565 1.00
18_I 22_T 1.558 1.00
227_R 284_E 1.544 1.00
53_A 57_S 1.536 1.00
7_V 93_V 1.52 1.00
247_M 262_P 1.517 1.00
117_L 190_I 1.515 1.00
10_F 44_K 1.478 1.00
160_S 163_V 1.472 1.00
2_K 86_D 1.461 1.00
108_K 113_A 1.448 1.00
105_L 118_A 1.446 1.00
24_R 58_D 1.422 0.99
229_W 278_G 1.404 0.99
49_S 53_A 1.399 0.99
81_D 299_Y 1.398 0.99
238_S 242_I 1.393 0.99
260_G 263_S 1.38 0.99
72_K 205_F 1.372 0.99
21_K 25_E 1.37 0.99
166_N 300_I 1.359 0.99
34_V 60_L 1.357 0.99
10_F 69_N 1.355 0.99
18_I 199_I 1.346 0.99
9_V 38_F 1.313 0.99
163_V 184_V 1.311 0.99
101_V 104_H 1.309 0.99
198_R 201_G 1.302 0.99
16_I 50_I 1.294 0.99
107_E 111_A 1.288 0.99
15_A 199_I 1.286 0.99
121_S 192_E 1.257 0.98
74_P 298_K 1.256 0.98
139_K 143_K 1.252 0.98
50_I 54_L 1.236 0.98
26_F 34_V 1.234 0.98
62_V 304_V 1.232 0.98
6_V 88_I 1.232 0.98
142_N 148_K 1.23 0.98
244_G 266_V 1.215 0.98
166_N 169_L 1.213 0.98
22_T 99_I 1.212 0.98
83_A 88_I 1.209 0.98
289_T 293_T 1.208 0.98
87_A 106_I 1.204 0.98
261_Y 265_L 1.195 0.98
6_V 79_G 1.181 0.97
128_R 132_K 1.176 0.97
7_V 91_I 1.17 0.97
52_N 65_S 1.169 0.97
80_L 90_P 1.168 0.97
22_T 25_E 1.166 0.97
3_I 26_F 1.165 0.97
9_V 93_V 1.163 0.97
117_L 188_T 1.158 0.97
91_I 99_I 1.147 0.97
10_F 40_N 1.137 0.96
106_I 110_Q 1.136 0.96
16_I 93_V 1.133 0.96
82_H 304_V 1.119 0.96
64_L 82_H 1.115 0.96
77_F 298_K 1.108 0.96
108_K 191_V 1.106 0.96
48_E 52_N 1.104 0.96
207_G 211_W 1.103 0.96
19_F 23_V 1.102 0.95
268_I 275_Q 1.1 0.95
62_V 84_T 1.09 0.95
159_M 164_V 1.087 0.95
40_N 48_E 1.087 0.95
246_W 250_D 1.077 0.95
5_L 91_I 1.07 0.94
173_R 295_K 1.064 0.94
256_N 259_R 1.06 0.94
20_Y 24_R 1.058 0.94
48_E 51_I 1.057 0.94
165_E 168_K 1.05 0.94
78_A 299_Y 1.049 0.94
3_I 32_Y 1.046 0.94
67_T 300_I 1.035 0.93
65_S 303_R 1.03 0.93
176_F 213_L 1.029 0.93
72_K 210_L 1.029 0.93
73_E 178_K 1.026 0.93
24_R 34_V 1.025 0.93
5_L 26_F 1.024 0.93
16_I 47_T 1.021 0.92
36_I 61_V 1.021 0.92
122_D 194_V 1.02 0.92
82_H 301_I 1.016 0.92
189_D 192_E 1.016 0.92
80_L 168_K 1.013 0.92
46_A 53_A 1.013 0.92
132_K 136_W 1.012 0.92
98_P 101_V 1.01 0.92
76_L 90_P 1.009 0.92
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
2bo4A60.86931000.618Contact Map0.524
2wvlA20.80721000.65Contact Map0.565
2zu9A20.84311000.652Contact Map0.498
3f1yA20.88891000.668Contact Map0.566
3ckjA10.83331000.669Contact Map0.601
2d7iA10.973999.90.685Contact Map0.577
2z86A40.78199.90.686Contact Map0.767
3bcvA20.68399.90.69Contact Map0.771
4fixA20.970699.90.709Contact Map0.629
3l7iA40.898799.90.711Contact Map
Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.
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