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OPENSEQ.org

YDJZ - TVP38/TMEM64 family inner membrane protein YdjZ
UniProt: P76221 Sequence
Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG14002
Length: 235 (220)
Sequences: 895
Seq/Len: 4.07

YDJZ
Paralog alert: 0.17 [within 20: 0.02] - ratio of genomes with paralogs
Cluster includes: YDJX YDJZ
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
68_F 105_S 2.869 1.00
64_A 101_L 2.376 1.00
67_S 89_N 2.36 1.00
63_A 93_F 2.322 1.00
111_A 178_F 2.019 1.00
68_F 101_L 1.998 1.00
173_R 176_S 1.992 1.00
99_G 190_I 1.868 1.00
161_D 164_S 1.796 1.00
146_K 180_A 1.703 0.99
153_R 181_T 1.7 0.99
55_F 59_Y 1.673 0.99
181_T 185_Q 1.625 0.99
25_L 29_L 1.59 0.99
210_L 214_F 1.587 0.99
126_E 138_D 1.579 0.98
68_F 104_T 1.546 0.98
107_M 178_F 1.516 0.98
141_F 145_G 1.496 0.98
160_F 185_Q 1.491 0.98
121_G 124_V 1.473 0.97
74_Q 161_D 1.442 0.97
117_A 168_G 1.441 0.97
89_N 102_S 1.439 0.97
122_R 138_D 1.439 0.97
75_A 109_G 1.42 0.96
95_A 99_G 1.416 0.96
135_D 139_G 1.381 0.96
163_I 177_F 1.38 0.96
106_S 185_Q 1.379 0.96
90_A 98_G 1.363 0.95
104_T 182_G 1.344 0.95
53_E 57_Q 1.341 0.95
111_A 174_F 1.34 0.95
71_M 86_T 1.335 0.94
109_G 156_P 1.318 0.94
86_T 189_T 1.317 0.94
122_R 125_V 1.298 0.93
56_I 63_A 1.293 0.93
149_I 180_A 1.293 0.93
67_S 93_F 1.291 0.93
148_T 152_C 1.29 0.93
96_F 100_L 1.285 0.93
114_F 117_A 1.281 0.93
72_I 108_A 1.261 0.92
66_V 214_F 1.235 0.91
71_M 160_F 1.225 0.90
103_W 182_G 1.218 0.90
161_D 177_F 1.215 0.90
26_A 32_G 1.211 0.90
37_I 44_F 1.195 0.89
96_F 99_G 1.191 0.89
22_A 29_L 1.191 0.89
78_A 161_D 1.189 0.89
97_W 100_L 1.174 0.88
213_L 216_L 1.173 0.88
103_W 186_L 1.168 0.87
95_A 190_I 1.167 0.87
72_I 105_S 1.163 0.87
94_G 98_G 1.156 0.87
110_A 160_F 1.154 0.87
20_L 29_L 1.145 0.86
13_R 16_L 1.145 0.86
121_G 168_G 1.144 0.86
60_G 63_A 1.143 0.86
18_I 25_L 1.134 0.85
65_V 69_L 1.133 0.85
83_F 160_F 1.128 0.85
101_L 104_T 1.125 0.85
19_L 36_F 1.121 0.84
74_Q 85_I 1.12 0.84
90_A 193_S 1.118 0.84
222_M 226_I 1.113 0.84
14_I 29_L 1.109 0.83
153_R 187_P 1.108 0.83
153_R 160_F 1.107 0.83
150_L 180_A 1.106 0.83
31_P 36_F 1.104 0.83
175_R 179_I 1.1 0.83
67_S 90_A 1.096 0.82
17_I 23_M 1.095 0.82
150_L 210_L 1.092 0.82
138_D 171_S 1.085 0.82
183_L 215_A 1.08 0.81
86_T 102_S 1.079 0.81
180_A 184_G 1.078 0.81
146_K 179_I 1.077 0.81
163_I 167_A 1.074 0.81
103_W 185_Q 1.064 0.80
23_M 39_R 1.063 0.80
15_T 18_I 1.055 0.79
117_A 169_L 1.05 0.79
167_A 170_T 1.049 0.78
19_L 31_P 1.049 0.78
23_M 26_A 1.046 0.78
12_Y 19_L 1.044 0.78
183_L 187_P 1.044 0.78
14_I 23_M 1.043 0.78
20_L 24_L 1.039 0.77
113_C 168_G 1.038 0.77
107_M 182_G 1.036 0.77
126_E 171_S 1.036 0.77
164_S 192_Y 1.033 0.77
150_L 183_L 1.032 0.77
19_L 28_A 1.032 0.77
18_I 23_M 1.031 0.77
164_S 168_G 1.027 0.76
146_K 150_L 1.022 0.76
153_R 180_A 1.013 0.75
90_A 96_F 1.007 0.74
110_A 153_R 1.007 0.74
88_A 181_T 1.006 0.74
19_L 26_A 1.004 0.74
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results:
PDB Chains Cov P(%) HHΔ   Acc
3rlbA20.706444.20.935Contact Map0.322
4huqS10.697928.20.941Contact Map0.266
3rlfG10.961725.50.942Contact Map0.2
3zuxA10.889414.70.949Contact Map0.151
3ilcA10.293612.10.95Contact Map0.531
2nq2A20.8511100.952Contact Map0.148
3k3fA10.66819.30.953Contact Map0.113
4eneA20.548990.953Contact Map0.181
2xa0A20.31498.10.954Contact Map0.531
3d31C20.94477.90.954Contact Map0.141

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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