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OPENSEQ.org
YDDH - Uncharacterized protein YddH
UniProt: P76121 Sequence
 Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG13779
Length: 189 (183)
Sequences: 2548
Seq/Len: 13.92
YDDH
Paralog alert: 0.50 [within 20: 0.05] - ratio of genomes with paralogs
Cluster includes: RUTF YDDH
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
72_F 144_G 4.194 1.00
128_R 145_E 3.485 1.00
105_P 119_E 3.337 1.00
128_R 147_V 3.329 1.00
130_L 145_E 3.051 1.00
28_D 33_R 2.872 1.00
97_D 100_N 2.755 1.00
25_T 73_G 2.585 1.00
109_G 126_E 2.465 1.00
29_E 68_H 2.422 1.00
107_V 118_E 2.378 1.00
111_V 147_V 2.312 1.00
79_V 169_N 2.244 1.00
36_I 117_V 2.022 1.00
85_T 179_F 1.975 1.00
58_K 135_A 1.97 1.00
52_V 74_I 1.953 1.00
72_F 127_C 1.947 1.00
71_K 128_R 1.869 1.00
27_F 34_R 1.84 1.00
53_A 141_T 1.804 1.00
63_R 140_D 1.791 1.00
77_P 85_T 1.788 1.00
109_G 116_L 1.764 1.00
105_P 118_E 1.761 1.00
28_D 31_S 1.728 1.00
73_G 112_F 1.725 1.00
112_F 126_E 1.703 1.00
92_S 101_C 1.697 1.00
34_R 106_V 1.657 1.00
127_C 144_G 1.65 1.00
8_E 11_H 1.612 1.00
73_G 116_L 1.609 1.00
26_S 66_I 1.569 1.00
116_L 124_W 1.564 1.00
109_G 112_F 1.521 1.00
77_P 171_L 1.511 1.00
36_I 88_V 1.505 1.00
79_V 181_T 1.439 1.00
67_E 133_T 1.439 1.00
51_R 130_L 1.438 1.00
86_W 179_F 1.437 1.00
45_V 53_A 1.428 1.00
27_F 113_G 1.424 1.00
114_L 126_E 1.418 1.00
63_R 67_E 1.411 1.00
23_L 88_V 1.406 0.99
157_V 164_D 1.395 0.99
129_L 142_L 1.391 0.99
51_R 143_F 1.378 0.99
52_V 125_M 1.361 0.99
71_K 114_L 1.358 0.99
64_E 94_R 1.343 0.99
37_M 62_T 1.337 0.99
110_P 148_S 1.334 0.99
99_F 106_V 1.328 0.99
109_G 114_L 1.326 0.99
19_G 40_A 1.316 0.99
36_I 99_F 1.301 0.99
34_R 115_P 1.3 0.99
64_E 68_H 1.285 0.99
71_K 112_F 1.263 0.99
27_F 108_R 1.262 0.99
71_K 113_G 1.259 0.99
81_A 119_E 1.255 0.99
92_S 96_E 1.246 0.98
131_P 134_S 1.231 0.98
75_V 124_W 1.213 0.98
78_G 81_A 1.205 0.98
22_V 42_S 1.202 0.98
77_P 121_C 1.186 0.98
25_T 36_I 1.18 0.98
164_D 167_K 1.179 0.98
38_A 85_T 1.15 0.97
42_S 52_V 1.137 0.97
51_R 136_Q 1.115 0.96
16_L 44_P 1.103 0.96
45_V 143_F 1.095 0.96
73_G 124_W 1.081 0.95
134_S 143_F 1.074 0.95
70_G 129_L 1.073 0.95
133_T 140_D 1.068 0.95
23_L 36_I 1.056 0.95
55_V 141_T 1.053 0.95
27_F 69_N 1.05 0.94
43_M 55_V 1.044 0.94
27_F 32_Q 1.014 0.93
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
1ejeA10.96831000.125Contact Map0.81
3bpkA20.97351000.129Contact Map0.854
3hmzA10.96831000.141Contact Map0.745
3fgeA10.97881000.144Contact Map0.829
2r6vA10.95241000.162Contact Map0.777
2d5mA10.94181000.172Contact Map0.88
3bnkA20.93121000.174Contact Map0.828
3e4vA20.92591000.184Contact Map0.765
1uscA20.93121000.187Contact Map0.785
1yoaA10.83071000.216Contact Map0.785
Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.
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