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SSUA - Putative aliphatic sulfonates-binding protein
UniProt: P75853 Sequence
 Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG13707
Length: 319 (286)
Sequences: 4850
Seq/Len: 16.96
SSUA
Paralog alert: 0.60 [within 20: 0.11] - ratio of genomes with paralogs
Cluster includes: SSUA TAUA
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
52_R 231_A 3.973 1.00
243_Q 246_Q 3.958 1.00
51_K 235_E 3.947 1.00
131_K 159_Q 3.685 1.00
239_L 243_Q 3.631 1.00
99_V 216_R 3.445 1.00
303_D 306_Q 3.316 1.00
217_P 221_K 3.304 1.00
128_K 157_D 3.277 1.00
249_A 259_A 3.213 1.00
52_R 235_E 3.204 1.00
227_Q 231_A 3.13 1.00
97_D 216_R 3.086 1.00
123_T 126_D 2.868 1.00
286_Q 290_D 2.859 1.00
32_G 78_I 2.795 1.00
133_A 177_V 2.754 1.00
218_Y 222_N 2.739 1.00
245_E 263_A 2.731 1.00
216_R 220_E 2.725 1.00
28_A 57_K 2.662 1.00
49_L 233_F 2.637 1.00
28_A 59_S 2.594 1.00
122_K 126_D 2.499 1.00
30_R 59_S 2.473 1.00
46_H 246_Q 2.43 1.00
48_L 235_E 2.396 1.00
154_K 157_D 2.334 1.00
153_L 157_D 2.167 1.00
224_A 228_G 2.164 1.00
238_A 242_S 2.144 1.00
290_D 294_E 2.136 1.00
293_Y 301_K 2.115 1.00
45_S 253_K 2.031 1.00
214_A 219_A 1.983 1.00
48_L 232_T 1.953 1.00
80_L 214_A 1.907 1.00
122_K 197_R 1.87 1.00
222_N 225_F 1.86 1.00
184_D 188_S 1.857 1.00
249_A 253_K 1.824 1.00
130_H 178_D 1.756 1.00
246_Q 249_A 1.734 1.00
127_L 179_A 1.72 1.00
214_A 226_I 1.717 1.00
80_L 226_I 1.714 1.00
239_L 246_Q 1.713 1.00
290_D 301_K 1.707 1.00
149_R 294_E 1.704 1.00
258_P 261_V 1.685 1.00
248_I 263_A 1.682 1.00
125_A 128_K 1.652 1.00
125_A 151_A 1.649 1.00
259_A 263_A 1.647 1.00
163_L 171_A 1.633 1.00
141_H 145_L 1.589 1.00
48_L 239_L 1.589 1.00
48_L 51_K 1.571 1.00
131_K 161_T 1.561 1.00
252_A 259_A 1.552 1.00
132_V 179_A 1.548 1.00
228_G 232_T 1.515 1.00
218_Y 225_F 1.505 1.00
102_G 230_L 1.503 1.00
240_T 247_S 1.488 1.00
148_L 158_I 1.486 1.00
263_A 267_D 1.485 1.00
223_G 227_Q 1.462 1.00
80_L 229_V 1.456 1.00
219_A 226_I 1.433 1.00
46_H 239_L 1.432 1.00
92_Q 216_R 1.424 1.00
44_K 50_E 1.421 1.00
218_Y 226_I 1.407 0.99
52_R 228_G 1.389 0.99
124_V 151_A 1.368 0.99
192_L 264_S 1.332 0.99
120_P 197_R 1.324 0.99
47_Q 50_E 1.313 0.99
52_R 232_T 1.305 0.99
215_A 218_Y 1.297 0.99
260_P 263_A 1.287 0.99
76_G 217_P 1.282 0.99
117_E 195_G 1.27 0.99
124_V 147_A 1.265 0.99
148_L 153_L 1.26 0.99
101_V 230_L 1.257 0.99
234_S 238_A 1.24 0.98
283_A 287_Q 1.228 0.98
117_E 197_R 1.219 0.98
63_F 72_A 1.21 0.98
291_L 295_N 1.2 0.98
43_A 236_A 1.2 0.98
144_L 160_P 1.198 0.98
131_K 178_D 1.193 0.98
99_V 219_A 1.19 0.98
116_A 175_G 1.189 0.98
45_S 254_T 1.189 0.98
113_I 127_L 1.186 0.98
74_N 96_A 1.184 0.98
218_Y 223_G 1.174 0.98
115_V 197_R 1.172 0.98
32_G 63_F 1.16 0.97
66_G 87_P 1.156 0.97
112_V 187_Y 1.153 0.97
100_Y 211_F 1.147 0.97
201_D 204_D 1.139 0.97
101_V 214_A 1.135 0.97
146_R 149_R 1.133 0.97
101_V 226_I 1.132 0.97
164_T 167_D 1.13 0.97
264_S 267_D 1.13 0.97
191_L 264_S 1.127 0.97
30_R 61_V 1.126 0.97
80_L 101_V 1.122 0.97
48_L 52_R 1.118 0.96
245_E 249_A 1.109 0.96
68_Q 71_E 1.108 0.96
42_L 239_L 1.102 0.96
43_A 49_L 1.099 0.96
223_G 226_I 1.098 0.96
282_A 305_R 1.076 0.95
31_I 229_V 1.074 0.95
132_V 158_I 1.074 0.95
42_L 46_H 1.07 0.95
69_M 81_G 1.067 0.95
224_A 227_Q 1.061 0.95
73_L 78_I 1.06 0.95
73_L 81_G 1.057 0.95
116_A 119_S 1.053 0.95
56_S 225_F 1.05 0.94
56_S 228_G 1.047 0.94
42_L 250_L 1.045 0.94
116_A 172_F 1.04 0.94
248_I 259_A 1.037 0.94
216_R 219_A 1.036 0.94
83_T 213_L 1.034 0.94
192_L 260_P 1.029 0.94
289_A 302_V 1.027 0.94
171_A 177_V 1.013 0.93
128_K 153_L 1.012 0.93
30_R 79_D 1.006 0.93
115_V 119_S 1.003 0.93
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
2x26A20.92481000.334Contact Map0.758
3qslA20.98431000.364Contact Map0.717
2g29A10.95921000.383Contact Map0.735
3un6A10.96551000.387Contact Map0.558
3ix1A20.89031000.39Contact Map0.74
2de3A20.92481000.395Contact Map0.636
4eswA20.91541000.404Contact Map0.709
2i49A10.93731000.418Contact Map0.665
2x7qA10.92481000.424Contact Map0.692
3ksxA10.98751000.447Contact Map0.73
Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.
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