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OPENSEQ.org

RCNR - Transcriptional repressor RcnR
UniProt: P64530 Sequence
Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG14070
Length: 90 (90)
Sequences: 1340
Seq/Len: 14.89

RCNR
Paralog alert: 0.46 [within 20: 0.01] - ratio of genomes with paralogs
Cluster includes: FRMR RCNR
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
19_Q 23_V 5.139 1.00
16_S 26_K 3.481 1.00
27_K 31_E 2.827 1.00
9_Q 13_A 2.81 1.00
22_V 45_I 2.485 1.00
25_L 45_I 2.414 1.00
18_I 22_V 2.037 1.00
34_E 37_A 1.806 1.00
13_A 17_K 1.764 1.00
7_D 10_K 1.683 1.00
8_K 32_P 1.621 1.00
10_K 13_A 1.5 1.00
14_R 48_A 1.492 1.00
12_K 26_K 1.464 1.00
45_I 49_V 1.433 1.00
15_A 22_V 1.417 1.00
18_I 52_L 1.402 0.99
46_R 50_N 1.38 0.99
15_A 29_L 1.375 0.99
34_E 80_V 1.362 0.99
5_I 32_P 1.358 0.99
17_K 48_A 1.34 0.99
17_K 21_Q 1.301 0.99
41_Q 44_A 1.234 0.98
42_I 53_M 1.213 0.98
36_A 80_V 1.205 0.98
11_L 29_L 1.195 0.98
42_I 56_V 1.181 0.98
19_Q 26_K 1.168 0.97
18_I 48_A 1.143 0.97
21_Q 24_A 1.133 0.97
79_D 83_K 1.099 0.96
15_A 52_L 1.099 0.96
12_K 30_D 1.072 0.95
33_H 37_A 1.057 0.95
19_Q 22_V 1.042 0.94
24_A 28_M 1.041 0.94
42_I 49_V 1.029 0.94
49_V 53_M 1.024 0.93
53_M 88_Y 1.022 0.93
59_G 63_E 1.014 0.93
75_E 79_D 1.012 0.93
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
2hh7A111000.067Contact Map0.446
4adzA211000.079Contact Map0.545
3aaiA40.977899.90.114Contact Map0.621
2fb5A30.911171.50.853Contact Map0.374
3hglA10.833316.50.9Contact Map0.392
3frtA2115.80.901Contact Map0.209
1gaxA20.755613.70.903Contact Map0.219
2gd5A4111.40.907Contact Map0.253
3v47C20.88896.40.917Contact Map0.344
2okuA20.56676.40.917Contact Map0.371

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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