| UniProt: | P63177 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG12483 | ||
| Length: | 243 (239) | ||
| Sequences: | 3741 | ||
| Seq/Len: | 15.65 |
| RLMB
Paralog alert: 0.62 [within 20: 0.01] - ratio of genomes with paralogs Cluster includes: RLMB TRML |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 195_M | 227_V | 4.495 | 1.00 | |
| 99_I | 192_A | 3.653 | 1.00 | |
| 112_C | 231_T | 3.536 | 1.00 | |
| 173_G | 210_C | 3.507 | 1.00 | |
| 229_V | 232_G | 3.308 | 1.00 | |
| 237_E | 240_R | 3.283 | 1.00 | |
| 204_R | 208_E | 3.017 | 1.00 | |
| 174_T | 234_C | 2.881 | 1.00 | |
| 195_M | 231_T | 2.478 | 1.00 | |
| 23_Q | 75_K | 2.462 | 1.00 | |
| 98_L | 112_C | 2.396 | 1.00 | |
| 173_G | 202_M | 2.253 | 1.00 | |
| 162_R | 209_H | 2.235 | 1.00 | |
| 175_A | 207_R | 2.165 | 1.00 | |
| 117_D | 149_V | 2.039 | 1.00 | |
| 119_A | 236_F | 2.009 | 1.00 | |
| 24_E | 51_Q | 2.002 | 1.00 | |
| 117_D | 220_G | 1.974 | 1.00 | |
| 11_V | 72_A | 1.952 | 1.00 | |
| 113_L | 124_V | 1.949 | 1.00 | |
| 101_D | 203_R | 1.947 | 1.00 | |
| 165_Q | 211_D | 1.839 | 1.00 | |
| 142_A | 146_A | 1.836 | 1.00 | |
| 58_L | 71_I | 1.827 | 1.00 | |
| 99_I | 161_M | 1.758 | 1.00 | |
| 161_M | 171_I | 1.746 | 1.00 | |
| 172_V | 214_I | 1.742 | 1.00 | |
| 156_N | 159_R | 1.733 | 1.00 | |
| 231_T | 235_L | 1.715 | 1.00 | |
| 123_A | 150_P | 1.707 | 1.00 | |
| 98_L | 235_L | 1.707 | 1.00 | |
| 111_A | 228_S | 1.7 | 1.00 | |
| 98_L | 116_A | 1.691 | 1.00 | |
| 145_A | 222_V | 1.662 | 1.00 | |
| 172_V | 191_L | 1.661 | 1.00 | |
| 180_H | 212_E | 1.652 | 1.00 | |
| 97_L | 123_A | 1.643 | 1.00 | |
| 119_A | 182_L | 1.597 | 1.00 | |
| 169_I | 190_R | 1.589 | 1.00 | |
| 118_A | 218_M | 1.581 | 1.00 | |
| 193_L | 234_C | 1.575 | 1.00 | |
| 139_K | 146_A | 1.541 | 1.00 | |
| 193_L | 238_A | 1.538 | 1.00 | |
| 25_V | 72_A | 1.528 | 1.00 | |
| 98_L | 121_V | 1.517 | 1.00 | |
| 182_L | 234_C | 1.516 | 1.00 | |
| 25_V | 43_L | 1.484 | 1.00 | |
| 194_V | 206_T | 1.484 | 1.00 | |
| 170_W | 212_E | 1.484 | 1.00 | |
| 95_P | 190_R | 1.466 | 1.00 | |
| 116_A | 121_V | 1.443 | 1.00 | |
| 194_V | 202_M | 1.442 | 1.00 | |
| 121_V | 235_L | 1.442 | 1.00 | |
| 117_D | 222_V | 1.427 | 1.00 | |
| 180_H | 184_Q | 1.423 | 1.00 | |
| 169_I | 192_A | 1.4 | 0.99 | |
| 5_I | 14_L | 1.395 | 0.99 | |
| 22_F | 72_A | 1.39 | 0.99 | |
| 123_A | 152_I | 1.389 | 0.99 | |
| 24_E | 73_R | 1.385 | 0.99 | |
| 117_D | 148_S | 1.377 | 0.99 | |
| 115_S | 232_G | 1.352 | 0.99 | |
| 100_L | 195_M | 1.348 | 0.99 | |
| 103_V | 227_V | 1.342 | 0.99 | |
| 116_A | 124_V | 1.337 | 0.99 | |
| 113_L | 151_L | 1.33 | 0.99 | |
| 171_I | 192_A | 1.329 | 0.99 | |
| 173_G | 213_L | 1.313 | 0.99 | |
| 96_F | 121_V | 1.305 | 0.99 | |
| 21_R | 75_K | 1.303 | 0.99 | |
| 182_L | 187_M | 1.3 | 0.99 | |
| 237_E | 241_Q | 1.298 | 0.99 | |
| 62_S | 71_I | 1.298 | 0.99 | |
| 13_A | 148_S | 1.296 | 0.99 | |
| 104_T | 199_G | 1.285 | 0.99 | |
| 176_G | 215_S | 1.282 | 0.99 | |
| 181_T | 184_Q | 1.281 | 0.99 | |
| 185_S | 214_I | 1.28 | 0.99 | |
| 53_A | 58_L | 1.28 | 0.99 | |
| 162_R | 166_E | 1.279 | 0.99 | |
| 117_D | 145_A | 1.279 | 0.99 | |
| 170_W | 211_D | 1.278 | 0.99 | |
| 205_L | 208_E | 1.261 | 0.99 | |
| 179_D | 215_S | 1.253 | 0.99 | |
| 55_R | 59_D | 1.25 | 0.99 | |
| 119_A | 233_I | 1.25 | 0.99 | |
| 175_A | 213_L | 1.242 | 0.98 | |
| 29_K | 54_N | 1.241 | 0.98 | |
| 195_M | 230_A | 1.225 | 0.98 | |
| 207_R | 213_L | 1.22 | 0.98 | |
| 99_I | 157_L | 1.2 | 0.98 | |
| 158_A | 209_H | 1.199 | 0.98 | |
| 30_G | 55_R | 1.199 | 0.98 | |
| 119_A | 239_V | 1.193 | 0.98 | |
| 197_A | 200_E | 1.193 | 0.98 | |
| 53_A | 57_Y | 1.19 | 0.98 | |
| 172_V | 212_E | 1.187 | 0.98 | |
| 164_L | 192_A | 1.175 | 0.98 | |
| 125_I | 160_T | 1.173 | 0.98 | |
| 97_L | 169_I | 1.163 | 0.97 | |
| 29_K | 52_L | 1.14 | 0.97 | |
| 97_L | 125_I | 1.138 | 0.97 | |
| 115_S | 119_A | 1.137 | 0.97 | |
| 101_D | 202_M | 1.132 | 0.97 | |
| 57_Y | 60_E | 1.116 | 0.96 | |
| 161_M | 206_T | 1.113 | 0.96 | |
| 238_A | 242_R | 1.11 | 0.96 | |
| 96_F | 238_A | 1.104 | 0.96 | |
| 113_L | 145_A | 1.103 | 0.96 | |
| 174_T | 195_M | 1.1 | 0.96 | |
| 159_R | 162_R | 1.083 | 0.96 | |
| 148_S | 221_S | 1.08 | 0.95 | |
| 84_D | 87_D | 1.069 | 0.95 | |
| 99_I | 164_L | 1.068 | 0.95 | |
| 102_G | 197_A | 1.053 | 0.95 | |
| 194_V | 210_C | 1.051 | 0.94 | |
| 13_A | 16_E | 1.05 | 0.94 | |
| 187_M | 191_L | 1.043 | 0.94 | |
| 126_V | 151_L | 1.039 | 0.94 | |
| 90_A | 167_E | 1.035 | 0.94 | |
| 28_L | 55_R | 1.035 | 0.94 | |
| 117_D | 221_S | 1.023 | 0.93 | |
| 95_P | 122_H | 1.02 | 0.93 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 1gz0A | 8 | 1 | 100 | 0.114 | Contact Map | 0.949 |
| 3nk6A | 2 | 0.963 | 100 | 0.156 | Contact Map | 0.795 |
| 1ipaA | 1 | 0.963 | 100 | 0.159 | Contact Map | 0.718 |
| 1x7oA | 2 | 0.963 | 100 | 0.178 | Contact Map | 0.731 |
| 2i6dA | 1 | 0.9218 | 100 | 0.197 | Contact Map | 0.79 |
| 4kgnA | 8 | 0.6296 | 100 | 0.379 | Contact Map | 0.637 |
| 1v2xA | 1 | 0.6914 | 100 | 0.389 | Contact Map | 0.767 |
| 1zjrA | 1 | 0.7037 | 100 | 0.39 | Contact Map | 0.779 |
| 3n4jA | 1 | 0.6255 | 100 | 0.391 | Contact Map | 0.593 |
| 3l8uA | 2 | 0.6502 | 100 | 0.392 | Contact Map | 0.703 |
Sequence Conservation (Image Generated using WebLogo v3)