| UniProt: | P61517 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG12319 | ||
| Length: | 220 (203) | ||
| Sequences: | 1824 | ||
| Seq/Len: | 8.99 |
| CAN
Paralog alert: 0.45 [within 20: 0.02] - ratio of genomes with paralogs Cluster includes: CAN CYNT |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 151_V | 178_G | 4.295 | 1.00 | |
| 159_G | 168_W | 3.802 | 1.00 | |
| 36_R | 91_E | 3.786 | 1.00 | |
| 67_A | 103_G | 2.906 | 1.00 | |
| 5_D | 9_S | 2.889 | 1.00 | |
| 155_V | 178_G | 2.831 | 1.00 | |
| 170_R | 173_K | 2.692 | 1.00 | |
| 82_Q | 86_D | 2.357 | 1.00 | |
| 66_V | 80_V | 2.343 | 1.00 | |
| 92_H | 177_H | 2.308 | 1.00 | |
| 165_Q | 169_K | 2.304 | 1.00 | |
| 33_Q | 45_S | 2.259 | 1.00 | |
| 38_L | 81_V | 2.18 | 1.00 | |
| 155_V | 176_I | 2.147 | 1.00 | |
| 147_C | 180_A | 2.105 | 1.00 | |
| 166_S | 170_R | 2.034 | 1.00 | |
| 84_A | 90_V | 1.9 | 1.00 | |
| 99_Y | 180_A | 1.897 | 1.00 | |
| 12_A | 187_L | 1.821 | 1.00 | |
| 85_V | 167_A | 1.796 | 1.00 | |
| 91_E | 173_K | 1.788 | 1.00 | |
| 89_E | 167_A | 1.783 | 1.00 | |
| 8_I | 190_D | 1.746 | 1.00 | |
| 78_L | 161_S | 1.723 | 1.00 | |
| 13_L | 54_G | 1.609 | 1.00 | |
| 9_S | 13_L | 1.579 | 1.00 | |
| 12_A | 16_K | 1.568 | 1.00 | |
| 167_A | 173_K | 1.554 | 1.00 | |
| 83_Y | 102_G | 1.487 | 1.00 | |
| 182_G | 185_D | 1.477 | 1.00 | |
| 53_T | 60_L | 1.466 | 1.00 | |
| 94_I | 179_W | 1.453 | 1.00 | |
| 39_W | 96_C | 1.435 | 0.99 | |
| 68_N | 150_N | 1.428 | 0.99 | |
| 63_H | 80_V | 1.419 | 0.99 | |
| 179_W | 188_L | 1.408 | 0.99 | |
| 182_G | 189_R | 1.407 | 0.99 | |
| 105_Q | 109_E | 1.405 | 0.99 | |
| 43_S | 61_F | 1.4 | 0.99 | |
| 148_E | 189_R | 1.385 | 0.99 | |
| 164_M | 174_V | 1.369 | 0.99 | |
| 108_V | 146_L | 1.364 | 0.99 | |
| 151_V | 155_V | 1.354 | 0.99 | |
| 143_L | 147_C | 1.342 | 0.99 | |
| 81_V | 158_L | 1.329 | 0.99 | |
| 38_L | 90_V | 1.293 | 0.99 | |
| 133_L | 145_T | 1.28 | 0.98 | |
| 105_Q | 143_L | 1.279 | 0.98 | |
| 32_A | 100_G | 1.277 | 0.98 | |
| 27_E | 30_A | 1.263 | 0.98 | |
| 17_M | 21_E | 1.263 | 0.98 | |
| 10_N | 14_W | 1.258 | 0.98 | |
| 159_G | 176_I | 1.245 | 0.98 | |
| 92_H | 175_T | 1.244 | 0.98 | |
| 43_S | 88_L | 1.239 | 0.98 | |
| 192_D | 199_E | 1.23 | 0.98 | |
| 38_L | 93_I | 1.22 | 0.98 | |
| 43_S | 63_H | 1.217 | 0.98 | |
| 157_N | 160_H | 1.217 | 0.98 | |
| 167_A | 174_V | 1.205 | 0.98 | |
| 53_T | 96_C | 1.198 | 0.97 | |
| 38_L | 80_V | 1.181 | 0.97 | |
| 100_G | 184_H | 1.18 | 0.97 | |
| 148_E | 180_A | 1.179 | 0.97 | |
| 39_W | 53_T | 1.167 | 0.97 | |
| 83_Y | 87_V | 1.131 | 0.96 | |
| 47_V | 62_V | 1.118 | 0.96 | |
| 85_V | 90_V | 1.115 | 0.96 | |
| 99_Y | 182_G | 1.105 | 0.95 | |
| 62_V | 65_N | 1.105 | 0.95 | |
| 65_N | 68_N | 1.099 | 0.95 | |
| 55_L | 59_E | 1.083 | 0.95 | |
| 96_C | 179_W | 1.081 | 0.94 | |
| 151_V | 180_A | 1.078 | 0.94 | |
| 104_V | 123_I | 1.076 | 0.94 | |
| 102_G | 116_I | 1.071 | 0.94 | |
| 41_G | 47_V | 1.06 | 0.94 | |
| 66_V | 103_G | 1.058 | 0.94 | |
| 126_I | 153_E | 1.056 | 0.94 | |
| 34_K | 89_E | 1.054 | 0.93 | |
| 13_L | 17_M | 1.054 | 0.93 | |
| 149_L | 152_M | 1.052 | 0.93 | |
| 85_V | 164_M | 1.04 | 0.93 | |
| 198_R | 203_Q | 1.038 | 0.93 | |
| 87_V | 116_I | 1.033 | 0.93 | |
| 33_Q | 102_G | 1.032 | 0.93 | |
| 25_F | 28_K | 1.031 | 0.92 | |
| 179_W | 190_D | 1.031 | 0.92 | |
| 134_L | 137_M | 1.03 | 0.92 | |
| 97_G | 151_V | 1.029 | 0.92 | |
| 158_L | 176_I | 1.002 | 0.91 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 3qy1A | 2 | 1 | 100 | 0.161 | Contact Map | 0.765 |
| 1ddzA | 2 | 1 | 100 | 0.167 | Contact Map | 0.62 |
| 3e3iA | 12 | 0.9955 | 100 | 0.174 | Contact Map | 0.72 |
| 3ucjA | 2 | 0.9682 | 100 | 0.194 | Contact Map | 0.74 |
| 2w3qA | 1 | 0.9091 | 100 | 0.202 | Contact Map | 0.649 |
| 1ekjA | 8 | 0.9182 | 100 | 0.221 | Contact Map | 0.759 |
| 3eyxA | 2 | 0.9 | 100 | 0.23 | Contact Map | 0.751 |
| 1ym3A | 1 | 0.8727 | 100 | 0.253 | Contact Map | 0.585 |
| 3vqjA | 1 | 0.8773 | 100 | 0.272 | Contact Map | 0.548 |
| 3lasA | 2 | 0.7409 | 100 | 0.347 | Contact Map | 0.7 |
Sequence Conservation (Image Generated using WebLogo v3)