| UniProt: | P55798 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG14026 | ||
| Length: | 218 (204) | ||
| Sequences: | 1680 | ||
| Seq/Len: | 8.24 |
| PRP1
Paralog alert: 0.46 [within 20: 0.01] - ratio of genomes with paralogs Cluster includes: PRP1 PRP2 |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 60_Q | 63_R | 6.462 | 1.00 | |
| 204_T | 213_T | 4.159 | 1.00 | |
| 30_E | 60_Q | 3.224 | 1.00 | |
| 29_L | 63_R | 3.126 | 1.00 | |
| 29_L | 33_R | 3.061 | 1.00 | |
| 50_S | 68_L | 2.891 | 1.00 | |
| 77_R | 82_Q | 2.668 | 1.00 | |
| 25_I | 64_C | 2.584 | 1.00 | |
| 35_K | 214_L | 2.58 | 1.00 | |
| 39_C | 214_L | 2.526 | 1.00 | |
| 29_L | 67_L | 2.518 | 1.00 | |
| 41_F | 46_D | 2.354 | 1.00 | |
| 49_I | 140_I | 2.313 | 1.00 | |
| 33_R | 67_L | 2.287 | 1.00 | |
| 32_L | 50_S | 2.152 | 1.00 | |
| 130_E | 181_D | 2.135 | 1.00 | |
| 182_H | 200_H | 2.1 | 1.00 | |
| 74_C | 129_L | 2.094 | 1.00 | |
| 128_I | 139_V | 2.078 | 1.00 | |
| 21_L | 140_I | 2.027 | 1.00 | |
| 25_I | 32_L | 2.013 | 1.00 | |
| 20_W | 39_C | 2.002 | 1.00 | |
| 66_Q | 118_A | 1.979 | 1.00 | |
| 82_Q | 86_D | 1.914 | 1.00 | |
| 47_L | 74_C | 1.911 | 1.00 | |
| 138_H | 217_L | 1.906 | 1.00 | |
| 28_C | 207_V | 1.854 | 1.00 | |
| 200_H | 215_V | 1.844 | 1.00 | |
| 51_V | 76_V | 1.84 | 1.00 | |
| 185_F | 201_Y | 1.82 | 1.00 | |
| 20_W | 216_Q | 1.783 | 1.00 | |
| 69_E | 118_A | 1.779 | 1.00 | |
| 28_C | 31_Q | 1.718 | 1.00 | |
| 22_S | 214_L | 1.626 | 1.00 | |
| 66_Q | 111_Q | 1.624 | 1.00 | |
| 49_I | 129_L | 1.622 | 1.00 | |
| 51_V | 140_I | 1.617 | 1.00 | |
| 185_F | 199_L | 1.609 | 1.00 | |
| 202_I | 215_V | 1.587 | 1.00 | |
| 32_L | 67_L | 1.583 | 1.00 | |
| 54_V | 64_C | 1.58 | 1.00 | |
| 55_I | 81_E | 1.525 | 1.00 | |
| 89_A | 123_Q | 1.504 | 1.00 | |
| 116_K | 120_E | 1.492 | 1.00 | |
| 21_L | 184_W | 1.474 | 0.99 | |
| 32_L | 64_C | 1.448 | 0.99 | |
| 184_W | 215_V | 1.441 | 0.99 | |
| 18_H | 46_D | 1.43 | 0.99 | |
| 50_S | 73_V | 1.43 | 0.99 | |
| 184_W | 202_I | 1.406 | 0.99 | |
| 66_Q | 109_D | 1.394 | 0.99 | |
| 189_P | 207_V | 1.375 | 0.99 | |
| 65_L | 122_C | 1.366 | 0.99 | |
| 62_L | 66_Q | 1.324 | 0.99 | |
| 88_L | 119_L | 1.324 | 0.99 | |
| 36_L | 67_L | 1.32 | 0.99 | |
| 83_M | 99_N | 1.301 | 0.98 | |
| 184_W | 200_H | 1.293 | 0.98 | |
| 66_Q | 69_E | 1.261 | 0.98 | |
| 56_D | 80_H | 1.254 | 0.98 | |
| 189_P | 201_Y | 1.253 | 0.98 | |
| 69_E | 117_T | 1.253 | 0.98 | |
| 18_H | 216_Q | 1.249 | 0.98 | |
| 139_V | 183_F | 1.235 | 0.98 | |
| 69_E | 121_K | 1.223 | 0.97 | |
| 21_L | 217_L | 1.222 | 0.97 | |
| 50_S | 75_A | 1.195 | 0.97 | |
| 138_H | 182_H | 1.18 | 0.97 | |
| 21_L | 138_H | 1.169 | 0.96 | |
| 68_L | 73_V | 1.169 | 0.96 | |
| 23_G | 213_T | 1.168 | 0.96 | |
| 151_E | 154_K | 1.147 | 0.96 | |
| 23_G | 204_T | 1.146 | 0.96 | |
| 205_G | 208_F | 1.145 | 0.96 | |
| 84_A | 96_W | 1.129 | 0.95 | |
| 31_Q | 209_G | 1.118 | 0.95 | |
| 121_K | 125_L | 1.11 | 0.95 | |
| 23_G | 202_I | 1.109 | 0.95 | |
| 68_L | 75_A | 1.108 | 0.95 | |
| 28_C | 206_A | 1.085 | 0.94 | |
| 33_R | 63_R | 1.062 | 0.93 | |
| 77_R | 85_M | 1.05 | 0.92 | |
| 31_Q | 206_A | 1.043 | 0.92 | |
| 24_D | 27_G | 1.039 | 0.92 | |
| 81_E | 85_M | 1.036 | 0.92 | |
| 54_V | 68_L | 1.033 | 0.91 | |
| 57_R | 80_H | 1.033 | 0.91 | |
| 66_Q | 117_T | 1.032 | 0.91 | |
| 42_D | 45_R | 1.031 | 0.91 | |
| 56_D | 100_G | 1.02 | 0.91 | |
| 206_A | 212_L | 1.017 | 0.91 | |
| 85_M | 123_Q | 1.007 | 0.90 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 2qjcA | 1 | 0.9725 | 100 | 0.395 | Contact Map | 0.793 |
| 2dfjA | 2 | 0.8899 | 100 | 0.403 | Contact Map | 0.844 |
| 1g5bA | 3 | 0.9817 | 100 | 0.419 | Contact Map | 0.809 |
| 4j6oA | 2 | 0.9358 | 100 | 0.438 | Contact Map | 0.808 |
| 2z72A | 1 | 0.9587 | 100 | 0.487 | Contact Map | 0.833 |
| 3icfA | 2 | 0.9312 | 100 | 0.538 | Contact Map | 0.758 |
| 3h63A | 2 | 0.9312 | 100 | 0.56 | Contact Map | 0.818 |
| 4i5lC | 2 | 0.9128 | 100 | 0.567 | Contact Map | 0.799 |
| 3e7aA | 2 | 0.9083 | 99.9 | 0.57 | Contact Map | 0.788 |
| 4il1A | 4 | 0.9083 | 99.9 | 0.572 | Contact Map | 0.74 |
Sequence Conservation (Image Generated using WebLogo v3)