| UniProt: | P52697 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG13231 | ||
| Length: | 331 (319) | ||
| Sequences: | 25225 | ||
| Seq/Len: | 79.08 |
| 6PGL
Paralog alert: 0.57 [within 20: 0.48] - ratio of genomes with paralogs Cluster includes: 6PGL YNCE |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 81_P | 98_V | 2.826 | 1.00 | |
| 60_V | 98_V | 2.657 | 1.00 | |
| 86_H | 99_G | 2.614 | 1.00 | |
| 40_P | 53_G | 2.565 | 1.00 | |
| 151_I | 192_C | 2.549 | 1.00 | |
| 180_H | 193_V | 2.454 | 1.00 | |
| 131_S | 145_A | 2.449 | 1.00 | |
| 51_Y | 96_V | 2.406 | 1.00 | |
| 35_P | 52_V | 2.348 | 1.00 | |
| 106_V | 144_P | 2.342 | 1.00 | |
| 15_I | 52_V | 2.326 | 1.00 | |
| 125_G | 144_P | 2.197 | 1.00 | |
| 233_D | 247_D | 2.166 | 1.00 | |
| 200_V | 246_C | 2.142 | 1.00 | |
| 51_Y | 89_T | 2.132 | 1.00 | |
| 51_Y | 62_A | 2.117 | 1.00 | |
| 107_S | 122_V | 2.117 | 1.00 | |
| 97_F | 141_L | 2.08 | 1.00 | |
| 61_L | 77_E | 2.047 | 1.00 | |
| 175_G | 192_C | 2.025 | 1.00 | |
| 97_F | 108_V | 2.024 | 1.00 | |
| 152_C | 171_T | 2.019 | 1.00 | |
| 61_L | 74_F | 2.006 | 1.00 | |
| 192_C | 203_W | 1.989 | 1.00 | |
| 201_D | 217_T | 1.971 | 1.00 | |
| 279_G | 293_G | 1.946 | 1.00 | |
| 97_F | 134_I | 1.933 | 1.00 | |
| 191_Y | 243_L | 1.873 | 1.00 | |
| 88_S | 133_N | 1.87 | 1.00 | |
| 191_Y | 236_I | 1.86 | 1.00 | |
| 107_S | 116_P | 1.834 | 1.00 | |
| 42_V | 88_S | 1.827 | 1.00 | |
| 254_T | 270_F | 1.823 | 1.00 | |
| 7_I | 43_V | 1.775 | 1.00 | |
| 133_N | 182_V | 1.77 | 1.00 | |
| 7_I | 50_L | 1.745 | 1.00 | |
| 253_I | 292_A | 1.736 | 1.00 | |
| 100_S | 103_A | 1.732 | 1.00 | |
| 90_D | 134_I | 1.716 | 1.00 | |
| 144_P | 154_F | 1.688 | 1.00 | |
| 16_H | 31_V | 1.664 | 1.00 | |
| 194_N | 197_N | 1.659 | 1.00 | |
| 254_T | 267_K | 1.644 | 1.00 | |
| 54_V | 57_E | 1.636 | 1.00 | |
| 135_S | 183_F | 1.624 | 1.00 | |
| 125_G | 129_C | 1.623 | 1.00 | |
| 201_D | 214_C | 1.613 | 1.00 | |
| 110_R | 113_D | 1.604 | 1.00 | |
| 193_V | 231_A | 1.599 | 1.00 | |
| 52_V | 63_Y | 1.58 | 1.00 | |
| 235_H | 281_N | 1.568 | 1.00 | |
| 98_V | 109_T | 1.556 | 1.00 | |
| 225_F | 246_C | 1.545 | 1.00 | |
| 143_V | 190_A | 1.535 | 1.00 | |
| 235_H | 280_F | 1.534 | 1.00 | |
| 130_H | 147_K | 1.529 | 1.00 | |
| 100_S | 105_N | 1.523 | 1.00 | |
| 182_V | 235_H | 1.491 | 1.00 | |
| 191_Y | 202_V | 1.488 | 1.00 | |
| 136_P | 183_F | 1.481 | 1.00 | |
| 278_R | 295_K | 1.479 | 1.00 | |
| 45_P | 93_G | 1.477 | 1.00 | |
| 51_Y | 87_I | 1.463 | 1.00 | |
| 85_T | 102_N | 1.462 | 1.00 | |
| 145_A | 178_P | 1.453 | 1.00 | |
| 175_G | 194_N | 1.433 | 1.00 | |
| 16_H | 28_L | 1.433 | 1.00 | |
| 64_R | 69_D | 1.425 | 1.00 | |
| 143_V | 183_F | 1.422 | 1.00 | |
| 53_G | 84_P | 1.42 | 1.00 | |
| 191_Y | 234_I | 1.416 | 1.00 | |
| 97_F | 132_A | 1.413 | 1.00 | |
| 290_I | 301_V | 1.41 | 1.00 | |
| 39_Q | 56_P | 1.4 | 0.99 | |
| 182_V | 234_I | 1.398 | 0.99 | |
| 155_T | 158_D | 1.396 | 0.99 | |
| 237_T | 282_V | 1.396 | 0.99 | |
| 194_N | 199_S | 1.382 | 0.99 | |
| 283_D | 287_K | 1.378 | 0.99 | |
| 8_A | 18_W | 1.375 | 0.99 | |
| 247_D | 277_P | 1.372 | 0.99 | |
| 184_H | 236_I | 1.363 | 0.99 | |
| 193_V | 234_I | 1.357 | 0.99 | |
| 99_G | 129_C | 1.355 | 0.99 | |
| 80_L | 109_T | 1.333 | 0.99 | |
| 91_H | 138_N | 1.331 | 0.99 | |
| 44_S | 48_R | 1.33 | 0.99 | |
| 204_E | 209_H | 1.316 | 0.99 | |
| 146_L | 150_R | 1.314 | 0.99 | |
| 28_L | 31_V | 1.311 | 0.99 | |
| 267_K | 270_F | 1.309 | 0.99 | |
| 125_G | 146_L | 1.308 | 0.99 | |
| 256_F | 267_K | 1.306 | 0.99 | |
| 88_S | 132_A | 1.301 | 0.99 | |
| 152_C | 162_L | 1.297 | 0.99 | |
| 214_C | 217_T | 1.295 | 0.99 | |
| 54_V | 59_R | 1.295 | 0.99 | |
| 81_P | 103_A | 1.29 | 0.99 | |
| 245_A | 289_L | 1.286 | 0.99 | |
| 53_G | 87_I | 1.283 | 0.99 | |
| 74_F | 77_E | 1.278 | 0.99 | |
| 81_P | 100_S | 1.277 | 0.99 | |
| 44_S | 89_T | 1.275 | 0.99 | |
| 238_P | 286_G | 1.273 | 0.99 | |
| 179_R | 196_L | 1.256 | 0.99 | |
| 125_G | 148_Q | 1.255 | 0.99 | |
| 246_C | 256_F | 1.252 | 0.99 | |
| 257_S | 260_E | 1.249 | 0.99 | |
| 203_W | 214_C | 1.246 | 0.98 | |
| 99_G | 132_A | 1.245 | 0.98 | |
| 90_D | 94_Q | 1.243 | 0.98 | |
| 133_N | 181_M | 1.234 | 0.98 | |
| 7_I | 17_V | 1.23 | 0.98 | |
| 175_G | 197_N | 1.22 | 0.98 | |
| 143_V | 181_M | 1.218 | 0.98 | |
| 185_P | 236_I | 1.218 | 0.98 | |
| 135_S | 139_R | 1.213 | 0.98 | |
| 185_P | 240_G | 1.201 | 0.98 | |
| 136_P | 187_E | 1.199 | 0.98 | |
| 91_H | 134_I | 1.198 | 0.98 | |
| 248_R | 252_L | 1.195 | 0.98 | |
| 7_I | 41_M | 1.186 | 0.98 | |
| 49_Y | 75_A | 1.181 | 0.98 | |
| 19_N | 23_E | 1.179 | 0.98 | |
| 220_M | 224_N | 1.17 | 0.97 | |
| 81_P | 84_P | 1.166 | 0.97 | |
| 245_A | 282_V | 1.16 | 0.97 | |
| 204_E | 208_P | 1.149 | 0.97 | |
| 145_A | 181_M | 1.147 | 0.97 | |
| 281_N | 327_V | 1.139 | 0.97 | |
| 290_I | 328_V | 1.139 | 0.97 | |
| 42_V | 87_I | 1.131 | 0.97 | |
| 35_P | 54_V | 1.13 | 0.97 | |
| 232_A | 249_T | 1.127 | 0.97 | |
| 40_P | 86_H | 1.122 | 0.97 | |
| 59_R | 77_E | 1.117 | 0.96 | |
| 10_P | 14_Q | 1.11 | 0.96 | |
| 233_D | 279_G | 1.11 | 0.96 | |
| 64_R | 75_A | 1.108 | 0.96 | |
| 9_S | 38_V | 1.105 | 0.96 | |
| 184_H | 188_Q | 1.095 | 0.96 | |
| 134_I | 156_V | 1.092 | 0.96 | |
| 197_N | 201_D | 1.089 | 0.96 | |
| 43_V | 65_I | 1.088 | 0.96 | |
| 150_R | 171_T | 1.085 | 0.96 | |
| 236_I | 258_V | 1.081 | 0.95 | |
| 296_S | 300_S | 1.075 | 0.95 | |
| 202_V | 218_L | 1.073 | 0.95 | |
| 242_H | 268_E | 1.071 | 0.95 | |
| 305_V | 308_Q | 1.07 | 0.95 | |
| 294_Q | 298_H | 1.064 | 0.95 | |
| 292_A | 302_Y | 1.063 | 0.95 | |
| 183_F | 205_L | 1.061 | 0.95 | |
| 250_A | 254_T | 1.06 | 0.95 | |
| 220_M | 256_F | 1.058 | 0.95 | |
| 255_V | 271_Q | 1.051 | 0.94 | |
| 233_D | 280_F | 1.05 | 0.94 | |
| 313_E | 316_R | 1.049 | 0.94 | |
| 189_Y | 215_V | 1.044 | 0.94 | |
| 81_P | 107_S | 1.033 | 0.94 | |
| 253_I | 280_F | 1.029 | 0.94 | |
| 247_D | 280_F | 1.028 | 0.94 | |
| 300_S | 316_R | 1.024 | 0.93 | |
| 86_H | 131_S | 1.019 | 0.93 | |
| 174_E | 203_W | 1.019 | 0.93 | |
| 103_A | 107_S | 1.019 | 0.93 | |
| 40_P | 87_I | 1.012 | 0.93 | |
| 95_F | 117_V | 1.007 | 0.93 | |
| 89_T | 282_V | 1.006 | 0.93 | |
| 54_V | 61_L | 1.004 | 0.93 | |
| 89_T | 111_L | 1.002 | 0.92 | |
| 182_V | 236_I | 1 | 0.92 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 1vyhC | 10 | 0.8097 | 100 | 0.036 | Contact Map | 0.9 |
| 4jsnD | 2 | 0.8912 | 100 | 0.067 | Contact Map | 0.785 |
| 3sfzA | 1 | 0.9063 | 100 | 0.076 | Contact Map | 0.755 |
| 3ow8A | 4 | 0.8187 | 100 | 0.079 | Contact Map | 0.878 |
| 4j0xA | 2 | 0.9033 | 100 | 0.097 | Contact Map | 0.604 |
| 1gotB | 1 | 0.8127 | 100 | 0.097 | Contact Map | 0.831 |
| 2ymuA | 2 | 0.855 | 100 | 0.106 | Contact Map | 0.938 |
| 4j87A | 1 | 0.8308 | 100 | 0.11 | Contact Map | 0.814 |
| 3iz6a | 1 | 0.855 | 100 | 0.12 | Contact Map | 0.659 |
| 3dm0A | 1 | 0.8248 | 100 | 0.127 | Contact Map | 0.863 |
Sequence Conservation (Image Generated using WebLogo v3)