May 4, 2021 - We are working on upgrading the webserver, some pages may not work.
OPENSEQ.org
YIDJ - Uncharacterized sulfatase YidJ
UniProt: P31447 Sequence
 Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG11705
Length: 497 (442)
Sequences: 3124
Seq/Len: 7.07
YIDJ
Paralog alert: 0.58 [within 20: 0.08] - ratio of genomes with paralogs
Cluster includes: ASLA YDEN YIDJ
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
337_A 351_N 5.562 1.00
38_E 313_R 4.695 1.00
388_D 403_D 4.226 1.00
167_S 190_Y 4.152 1.00
403_D 406_N 4.045 1.00
267_N 271_P 3.94 1.00
388_D 405_R 3.871 1.00
390_K 410_E 3.574 1.00
20_G 33_D 3.493 1.00
31_N 263_G 3.434 1.00
11_T 14_Q 3.407 1.00
168_N 264_R 3.312 1.00
175_Q 268_A 3.306 1.00
34_S 270_T 3.242 1.00
266_I 279_V 3.2 1.00
423_V 426_K 3.006 1.00
203_Y 260_D 3.004 1.00
45_A 326_V 3.002 1.00
6_F 88_F 2.849 1.00
67_Q 348_P 2.843 1.00
207_Y 256_D 2.781 1.00
188_V 265_V 2.749 1.00
41_R 321_Q 2.68 1.00
171_V 268_A 2.607 1.00
201_V 205_E 2.574 1.00
170_A 186_M 2.561 1.00
268_A 272_E 2.54 1.00
6_F 339_A 2.525 1.00
278_W 312_I 2.406 1.00
7_L 279_V 2.384 1.00
169_R 172_D 2.376 1.00
43_N 323_D 2.375 1.00
21_C 41_R 2.343 1.00
14_Q 281_Y 2.261 1.00
91_A 341_I 2.237 1.00
31_N 34_S 2.213 1.00
206_K 256_D 2.181 1.00
167_S 265_V 2.168 1.00
98_I 186_M 2.115 1.00
84_M 185_L 2.097 1.00
268_A 271_P 2.09 1.00
314_S 317_G 2.084 1.00
278_W 338_L 2.08 1.00
331_L 335_M 2.07 1.00
29_T 33_D 2.037 1.00
32_I 281_Y 2.036 1.00
35_L 311_I 2.03 1.00
10_M 282_T 2.025 1.00
391_L 399_D 2.016 1.00
204_L 253_A 1.994 1.00
39_G 311_I 1.968 1.00
9_V 262_I 1.957 1.00
55_A 328_H 1.952 1.00
42_F 310_L 1.938 1.00
11_T 281_Y 1.936 1.00
261_Q 264_R 1.894 1.00
171_V 264_R 1.893 1.00
400_E 413_N 1.883 1.00
28_N 256_D 1.855 1.00
414_L 420_F 1.849 1.00
164_H 261_Q 1.834 1.00
280_I 335_M 1.823 1.00
40_I 320_R 1.822 1.00
8_F 280_I 1.816 1.00
336_M 341_I 1.807 1.00
40_I 322_V 1.774 1.00
34_S 267_N 1.761 1.00
21_C 33_D 1.75 1.00
34_S 266_I 1.74 1.00
96_C 173_F 1.732 1.00
175_Q 272_E 1.728 1.00
43_N 321_Q 1.724 1.00
337_A 353_L 1.717 1.00
420_F 423_V 1.695 1.00
175_Q 271_P 1.68 1.00
34_S 38_E 1.672 1.00
5_N 184_F 1.67 1.00
63_I 81_I 1.657 1.00
46_Y 306_T 1.641 1.00
202_E 260_D 1.634 1.00
22_Y 41_R 1.617 1.00
193_P 255_N 1.616 1.00
167_S 171_V 1.613 1.00
415_I 424_R 1.606 1.00
47_T 308_I 1.598 1.00
170_A 188_V 1.597 1.00
390_K 404_R 1.588 1.00
7_L 184_F 1.586 1.00
11_T 258_V 1.545 1.00
161_T 257_F 1.542 0.99
172_D 176_Q 1.534 0.99
386_T 430_A 1.526 0.99
46_Y 303_D 1.522 0.99
280_I 312_I 1.52 0.99
398_S 413_N 1.512 0.99
417_D 420_F 1.507 0.99
8_F 185_L 1.504 0.99
163_A 192_E 1.492 0.99
167_S 261_Q 1.48 0.99
326_V 352_I 1.48 0.99
424_R 428_H 1.47 0.99
278_W 314_S 1.459 0.99
389_F 401_L 1.456 0.99
38_E 270_T 1.453 0.99
14_Q 193_P 1.45 0.99
64_Y 329_I 1.441 0.99
5_N 277_T 1.439 0.99
13_T 287_E 1.439 0.99
14_Q 255_N 1.433 0.99
9_V 265_V 1.433 0.99
47_T 55_A 1.401 0.99
4_P 276_N 1.399 0.99
363_V 430_A 1.387 0.99
20_G 29_T 1.385 0.99
35_L 262_I 1.381 0.99
200_P 203_Y 1.371 0.99
36_A 41_R 1.37 0.99
302_Y 400_E 1.355 0.98
418_I 421_A 1.352 0.98
270_T 313_R 1.346 0.98
7_L 186_M 1.345 0.98
94_H 182_E 1.337 0.98
386_T 426_K 1.336 0.98
184_F 277_T 1.332 0.98
190_Y 261_Q 1.328 0.98
7_L 269_L 1.311 0.98
28_N 207_Y 1.306 0.98
333_P 349_G 1.302 0.98
97_Y 187_V 1.3 0.98
412_H 417_D 1.299 0.98
166_I 188_V 1.272 0.97
256_D 260_D 1.272 0.97
89_K 107_D 1.271 0.97
399_D 428_H 1.253 0.97
6_F 338_L 1.234 0.97
303_D 385_V 1.233 0.97
13_T 285_H 1.232 0.97
389_F 423_V 1.232 0.97
184_F 274_R 1.229 0.97
391_L 424_R 1.225 0.96
33_D 37_A 1.223 0.96
430_A 433_D 1.22 0.96
52_C 56_R 1.21 0.96
420_F 424_R 1.21 0.96
240_V 243_D 1.204 0.96
279_V 313_R 1.201 0.96
391_L 428_H 1.2 0.96
303_D 390_K 1.198 0.96
88_F 335_M 1.193 0.96
421_A 424_R 1.19 0.96
77_P 83_T 1.189 0.96
171_V 265_V 1.185 0.95
35_L 313_R 1.178 0.95
203_Y 256_D 1.168 0.95
391_L 427_M 1.168 0.95
35_L 39_G 1.164 0.95
8_F 282_T 1.16 0.95
421_A 425_S 1.16 0.95
190_Y 258_V 1.155 0.95
88_F 341_I 1.154 0.95
48_C 327_S 1.152 0.94
24_G 252_F 1.152 0.94
87_Y 91_A 1.146 0.94
21_C 32_I 1.142 0.94
426_K 430_A 1.134 0.94
7_L 265_V 1.124 0.93
164_H 257_F 1.123 0.93
205_E 208_A 1.123 0.93
310_L 326_V 1.122 0.93
66_N 367_R 1.116 0.93
416_D 424_R 1.109 0.93
265_V 268_A 1.108 0.93
16_T 307_R 1.107 0.93
162_W 166_I 1.107 0.93
63_I 67_Q 1.091 0.92
389_F 403_D 1.084 0.92
266_I 270_T 1.082 0.92
206_K 260_D 1.081 0.92
278_W 335_M 1.078 0.91
314_S 338_L 1.076 0.91
10_M 59_L 1.075 0.91
163_A 261_Q 1.07 0.91
417_D 421_A 1.069 0.91
258_V 281_Y 1.067 0.91
209_D 249_P 1.061 0.91
363_V 386_T 1.06 0.91
93_Y 339_A 1.06 0.91
6_F 335_M 1.058 0.90
257_F 261_Q 1.058 0.90
338_L 353_L 1.057 0.90
174_L 265_V 1.053 0.90
87_Y 336_M 1.053 0.90
9_V 279_V 1.052 0.90
269_L 315_P 1.051 0.90
42_F 355_V 1.041 0.89
10_M 189_S 1.036 0.89
19_V 29_T 1.034 0.89
174_L 177_P 1.032 0.89
28_N 206_K 1.025 0.89
97_Y 101_W 1.024 0.88
29_T 32_I 1.024 0.88
202_E 206_K 1.024 0.88
45_A 310_L 1.017 0.88
383_C 390_K 1.015 0.88
199_C 253_A 1.015 0.88
82_S 90_D 1.007 0.87
2_K 276_N 1.007 0.87
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
2vqrA10.90541000.295Contact Map0.778
1hdhA20.81491000.334Contact Map0.798
3b5qA20.87121000.342Contact Map0.73
2qzuA10.85511000.342Contact Map0.809
1aukA10.81891000.351Contact Map0.735
1p49A10.8351000.362Contact Map0.775
3ed4A40.85511000.371Contact Map0.87
1fsuA10.8371000.373Contact Map0.769
4fdiA20.8311000.375Contact Map0.813
3lxqA20.72641000.499Contact Map0.678
Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.
Page generated in 0.4287 seconds.