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FTSP - Cell division protein FtsP
UniProt: P26648 Sequence
 Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG11376
Length: 470 (460)
Sequences: 2385
Seq/Len: 5.18
FTSP
Paralog alert: 0.60 [within 20: 0.04] - ratio of genomes with paralogs
Cluster includes: CUEO FTSP
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
80_R 164_E 5.303 1.00
88_K 129_V 4.357 1.00
277_E 421_K 4.131 1.00
86_D 129_V 3.984 1.00
228_W 282_L 3.495 1.00
273_L 279_R 3.319 1.00
91_Y 120_M 3.261 1.00
78_T 160_M 3.05 1.00
92_S 125_D 2.922 1.00
49_F 90_I 2.916 1.00
90_I 127_A 2.806 1.00
233_L 244_L 2.708 1.00
121_S 124_A 2.668 1.00
141_Y 159_G 2.613 1.00
184_V 233_L 2.584 1.00
233_L 281_I 2.576 1.00
51_T 94_R 2.475 1.00
49_F 92_S 2.46 1.00
388_V 396_F 2.404 1.00
83_K 165_D 2.368 1.00
237_S 242_Y 2.358 1.00
160_M 234_L 2.347 1.00
251_P 267_S 2.333 1.00
228_W 284_D 2.318 1.00
252_L 281_I 2.264 1.00
278_R 422_D 2.219 1.00
387_T 431_E 2.211 1.00
55_A 69_G 2.195 1.00
185_I 236_A 2.169 1.00
451_Q 455_M 2.154 1.00
256_S 280_E 2.15 1.00
246_M 293_I 2.069 1.00
57_W 67_V 2.012 1.00
449_N 455_M 2.01 1.00
450_S 455_M 1.965 1.00
407_N 431_E 1.934 1.00
241_R 425_W 1.914 1.00
233_L 271_L 1.913 1.00
251_P 269_K 1.887 1.00
82_W 164_E 1.884 1.00
224_V 285_M 1.861 1.00
47_P 88_K 1.85 1.00
246_M 252_L 1.839 1.00
385_R 406_R 1.825 1.00
231_L 281_I 1.808 1.00
67_V 189_K 1.806 1.00
230_R 280_E 1.798 1.00
68_W 155_N 1.792 1.00
388_V 432_L 1.775 1.00
68_W 96_T 1.761 1.00
112_L 126_W 1.733 1.00
81_V 87_V 1.727 1.00
447_Y 461_I 1.725 1.00
244_L 293_I 1.721 1.00
192_D 196_T 1.677 0.99
379_Q 382_T 1.673 0.99
160_M 185_I 1.67 0.99
54_R 66_S 1.669 0.99
403_F 432_L 1.667 0.99
364_I 396_F 1.664 0.99
69_G 74_Y 1.658 0.99
401_V 466_V 1.648 0.99
257_G 279_R 1.64 0.99
385_R 433_L 1.631 0.99
230_R 255_I 1.623 0.99
143_A 152_Q 1.604 0.99
404_Q 420_W 1.566 0.99
90_I 125_D 1.552 0.99
254_V 279_R 1.55 0.99
158_A 187_Q 1.547 0.99
138_T 232_R 1.543 0.99
47_P 90_I 1.536 0.99
7_Q 10_Q 1.532 0.99
77_P 159_G 1.522 0.99
58_S 62_G 1.517 0.99
271_L 279_R 1.513 0.99
160_M 183_P 1.502 0.99
86_D 131_P 1.495 0.99
394_Q 450_S 1.491 0.99
247_N 294_T 1.482 0.98
456_A 461_I 1.479 0.98
52_V 91_Y 1.474 0.98
158_A 236_A 1.471 0.98
83_K 166_E 1.468 0.98
56_H 64_R 1.461 0.98
246_M 283_V 1.457 0.98
394_Q 451_Q 1.453 0.98
227_G 285_M 1.409 0.98
46_Q 85_D 1.405 0.98
424_V 430_V 1.398 0.98
394_Q 455_M 1.396 0.98
181_D 230_R 1.389 0.97
58_S 61_P 1.375 0.97
359_G 363_G 1.36 0.97
405_I 424_V 1.358 0.97
52_V 70_I 1.352 0.97
98_N 121_S 1.349 0.97
81_V 163_V 1.343 0.97
48_L 81_V 1.34 0.97
76_G 216_G 1.339 0.97
440_S 446_F 1.33 0.96
445_P 465_L 1.329 0.96
77_P 141_Y 1.329 0.96
243_Q 272_S 1.32 0.96
154_Y 238_N 1.317 0.96
398_I 434_V 1.315 0.96
91_Y 99_V 1.31 0.96
274_A 425_W 1.299 0.96
254_V 268_V 1.298 0.96
22_P 25_A 1.298 0.96
181_D 232_R 1.294 0.96
54_R 96_T 1.292 0.96
396_F 448_F 1.291 0.96
103_V 130_L 1.29 0.96
104_A 450_S 1.259 0.95
385_R 431_E 1.258 0.95
144_N 451_Q 1.257 0.95
232_R 280_E 1.253 0.94
144_N 450_S 1.248 0.94
381_G 436_F 1.246 0.94
250_R 291_V 1.243 0.94
350_P 353_S 1.243 0.94
388_V 448_F 1.242 0.94
400_G 446_F 1.238 0.94
102_T 399_E 1.237 0.94
99_V 152_Q 1.231 0.94
6_R 9_I 1.23 0.94
100_S 116_P 1.224 0.94
386_W 432_L 1.218 0.93
104_A 142_H 1.214 0.93
87_V 130_L 1.21 0.93
283_V 293_I 1.204 0.93
370_D 373_R 1.203 0.93
88_K 127_A 1.197 0.93
104_A 451_Q 1.196 0.93
153_V 453_L 1.194 0.92
394_Q 449_N 1.191 0.92
144_N 399_E 1.188 0.92
253_H 267_S 1.187 0.92
104_A 394_Q 1.181 0.92
52_V 99_V 1.181 0.92
53_Q 94_R 1.18 0.92
104_A 144_N 1.172 0.91
395_A 452_T 1.167 0.91
243_Q 270_Q 1.165 0.91
104_A 455_M 1.163 0.91
5_R 8_F 1.163 0.91
120_M 126_W 1.16 0.91
271_L 281_I 1.154 0.91
78_T 183_P 1.148 0.90
288_G 291_V 1.141 0.90
455_M 460_S 1.136 0.90
353_S 387_T 1.135 0.90
56_H 66_S 1.134 0.90
78_T 162_L 1.134 0.90
102_T 394_Q 1.131 0.89
186_I 242_Y 1.131 0.89
182_F 231_L 1.13 0.89
233_L 273_L 1.124 0.89
182_F 222_V 1.118 0.89
186_I 244_L 1.117 0.89
445_P 463_Q 1.116 0.89
142_H 450_S 1.115 0.89
377_T 465_L 1.115 0.89
144_N 455_M 1.108 0.88
259_Q 402_M 1.107 0.88
144_N 449_N 1.101 0.88
87_V 161_W 1.097 0.87
128_P 137_A 1.089 0.87
144_N 394_Q 1.089 0.87
451_Q 460_S 1.086 0.87
394_Q 399_E 1.085 0.87
91_Y 103_V 1.085 0.87
139_L 259_Q 1.082 0.87
448_F 462_G 1.082 0.87
212_L 295_C 1.078 0.86
453_L 456_A 1.077 0.86
407_N 429_Q 1.071 0.86
256_S 261_F 1.071 0.86
403_F 424_V 1.07 0.86
102_T 144_N 1.068 0.86
399_E 451_Q 1.066 0.85
106_L 161_W 1.064 0.85
449_N 460_S 1.063 0.85
252_L 283_V 1.061 0.85
51_T 92_S 1.06 0.85
102_T 113_M 1.055 0.85
103_V 400_G 1.055 0.85
117_A 126_W 1.053 0.84
153_V 158_A 1.053 0.84
8_F 12_S 1.05 0.84
393_P 425_W 1.05 0.84
5_R 9_I 1.049 0.84
399_E 449_N 1.043 0.84
78_T 141_Y 1.041 0.84
383_W 435_Y 1.032 0.83
159_G 216_G 1.029 0.83
245_Q 270_Q 1.028 0.82
238_N 454_E 1.025 0.82
224_V 229_V 1.021 0.82
399_E 450_S 1.021 0.82
102_T 451_Q 1.013 0.81
352_R 382_T 1.012 0.81
104_A 113_M 1.012 0.81
71_N 75_L 1.011 0.81
260_G 402_M 1.01 0.81
354_R 358_L 1.009 0.81
450_S 460_S 1.009 0.81
244_L 271_L 1.009 0.81
104_A 449_N 1.009 0.81
140_W 144_N 1.009 0.81
257_G 421_K 1.007 0.81
254_V 271_L 1.006 0.81
91_Y 101_M 1 0.80
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
2uxtA20.92551000.164Contact Map0.747
4e9sA10.92131000.189Contact Map0.736
2xu9A10.88511000.214Contact Map0.762
3abgA20.92981000.214Contact Map0.704
3zx1A10.93831000.217Contact Map0.703
2g23A120.94891000.242Contact Map0.756
2wsdA10.91281000.244Contact Map0.742
1zpuA60.87231000.257Contact Map0.795
3aw5A10.87661000.26Contact Map0.712
3sqrA10.95531000.266Contact Map0.749
Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.
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