| UniProt: | P23898 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG11133 | ||
| Length: | 154 (142) | ||
| Sequences: | 1247 | ||
| Seq/Len: | 8.78 |
| NLPC
Paralog alert: 0.58 [within 20: 0.03] - ratio of genomes with paralogs Cluster includes: NLPC SPR |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 54_G | 59_G | 2.989 | 1.00 | |
| 89_G | 152_R | 2.756 | 1.00 | |
| 97_L | 151_A | 2.727 | 1.00 | |
| 60_V | 68_V | 2.572 | 1.00 | |
| 120_D | 136_R | 2.556 | 1.00 | |
| 66_V | 118_I | 2.53 | 1.00 | |
| 42_L | 126_I | 2.523 | 1.00 | |
| 86_A | 150_Q | 2.327 | 1.00 | |
| 148_F | 151_A | 2.255 | 1.00 | |
| 66_V | 85_Q | 2.186 | 1.00 | |
| 113_G | 149_W | 2.117 | 1.00 | |
| 102_L | 116_V | 2.094 | 1.00 | |
| 56_T | 59_G | 2.021 | 1.00 | |
| 129_S | 132_K | 1.97 | 1.00 | |
| 41_Q | 74_F | 1.71 | 1.00 | |
| 107_T | 114_L | 1.665 | 1.00 | |
| 48_T | 59_G | 1.652 | 1.00 | |
| 57_R | 68_V | 1.622 | 1.00 | |
| 66_V | 116_V | 1.588 | 1.00 | |
| 117_G | 125_F | 1.562 | 1.00 | |
| 119_Y | 123_N | 1.557 | 1.00 | |
| 38_L | 74_F | 1.538 | 1.00 | |
| 41_Q | 45_W | 1.497 | 1.00 | |
| 79_P | 88_I | 1.485 | 1.00 | |
| 69_T | 118_I | 1.472 | 1.00 | |
| 45_W | 48_T | 1.472 | 1.00 | |
| 55_M | 80_R | 1.455 | 0.99 | |
| 104_F | 116_V | 1.452 | 0.99 | |
| 48_T | 134_V | 1.449 | 0.99 | |
| 103_V | 151_A | 1.416 | 0.99 | |
| 70_M | 78_L | 1.389 | 0.99 | |
| 124_Q | 138_S | 1.375 | 0.99 | |
| 57_R | 60_V | 1.362 | 0.99 | |
| 46_H | 126_I | 1.359 | 0.99 | |
| 91_Q | 152_R | 1.34 | 0.99 | |
| 81_E | 84_Q | 1.337 | 0.99 | |
| 62_C | 115_H | 1.336 | 0.99 | |
| 103_V | 117_G | 1.326 | 0.99 | |
| 94_K | 97_L | 1.326 | 0.99 | |
| 67_V | 80_R | 1.324 | 0.99 | |
| 82_T | 86_A | 1.32 | 0.99 | |
| 125_F | 139_L | 1.307 | 0.99 | |
| 97_L | 148_F | 1.28 | 0.98 | |
| 129_S | 133_G | 1.27 | 0.98 | |
| 43_Q | 126_I | 1.248 | 0.98 | |
| 123_N | 140_D | 1.239 | 0.98 | |
| 36_A | 99_P | 1.238 | 0.98 | |
| 130_T | 133_G | 1.21 | 0.97 | |
| 94_K | 148_F | 1.194 | 0.97 | |
| 65_F | 69_T | 1.183 | 0.97 | |
| 67_V | 85_Q | 1.177 | 0.97 | |
| 97_L | 119_Y | 1.166 | 0.97 | |
| 115_H | 127_H | 1.157 | 0.96 | |
| 39_N | 42_L | 1.125 | 0.96 | |
| 107_T | 147_N | 1.124 | 0.96 | |
| 105_F | 117_G | 1.122 | 0.96 | |
| 43_Q | 136_R | 1.121 | 0.96 | |
| 78_L | 85_Q | 1.12 | 0.95 | |
| 105_F | 125_F | 1.076 | 0.94 | |
| 108_G | 114_L | 1.07 | 0.94 | |
| 93_D | 96_E | 1.059 | 0.93 | |
| 79_P | 85_Q | 1.032 | 0.92 | |
| 127_H | 137_S | 1.026 | 0.92 | |
| 48_T | 54_G | 1.024 | 0.92 | |
| 125_F | 143_Y | 1.015 | 0.91 | |
| 129_S | 144_W | 1.015 | 0.91 | |
| 119_Y | 122_N | 1.013 | 0.91 | |
| 91_Q | 150_Q | 1.005 | 0.91 | |
| 80_R | 84_Q | 1.003 | 0.91 | |
| 82_T | 113_G | 1.001 | 0.91 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 2jyxA | 1 | 0.7987 | 100 | 0.283 | Contact Map | 0.744 |
| 3h41A | 1 | 0.9935 | 100 | 0.309 | Contact Map | 0.764 |
| 3npfA | 2 | 0.9805 | 100 | 0.314 | Contact Map | 0.802 |
| 4hpeA | 6 | 0.9805 | 100 | 0.316 | Contact Map | 0.772 |
| 4fdyA | 2 | 0.9805 | 100 | 0.322 | Contact Map | 0.768 |
| 2hbwA | 1 | 0.9675 | 100 | 0.336 | Contact Map | 0.724 |
| 3pbiA | 1 | 0.9545 | 100 | 0.345 | Contact Map | 0.743 |
| 3gt2A | 1 | 0.8182 | 100 | 0.35 | Contact Map | 0.72 |
| 3ne0A | 1 | 0.9416 | 100 | 0.36 | Contact Map | 0.761 |
| 3m1uA | 2 | 0.9545 | 100 | 0.367 | Contact Map | 0.415 |
Sequence Conservation (Image Generated using WebLogo v3)