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OPENSEQ.org

PSPE - Thiosulfate sulfurtransferase PspE
UniProt: P23857 Sequence
Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG10780
Length: 104 (84)
Sequences: 3841
Seq/Len: 45.73

PSPE
Paralog alert: 0.66 [within 20: 0.05] - ratio of genomes with paralogs
Cluster includes: GLPE PSPE YIBN
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
32_Y 36_H 3.753 1.00
51_R 54_T 2.825 1.00
32_Y 42_N 2.571 1.00
31_Q 72_Q 2.405 1.00
29_P 33_Q 2.219 1.00
64_K 91_A 2.051 1.00
28_V 46_K 2.032 1.00
65_V 80_L 1.935 1.00
66_Y 94_L 1.918 1.00
68_N 95_K 1.903 1.00
45_L 76_A 1.819 1.00
79_I 83_M 1.693 1.00
49_K 79_I 1.648 1.00
22_H 41_I 1.636 1.00
29_P 42_N 1.627 1.00
73_S 90_N 1.626 1.00
24_I 65_V 1.531 1.00
91_A 97_I 1.516 1.00
48_V 76_A 1.509 1.00
62_T 89_E 1.493 1.00
47_E 51_R 1.468 1.00
22_H 61_D 1.449 1.00
62_T 87_H 1.447 1.00
59_K 85_Y 1.44 1.00
35_E 98_A 1.428 1.00
77_K 88_V 1.409 1.00
32_Y 40_A 1.404 0.99
23_W 66_Y 1.394 0.99
37_V 66_Y 1.371 0.99
92_G 96_D 1.293 0.99
36_H 66_Y 1.278 0.99
35_E 94_L 1.257 0.99
21_E 64_K 1.232 0.98
67_C 70_G 1.212 0.98
37_V 97_I 1.12 0.96
26_V 76_A 1.116 0.96
22_H 58_D 1.091 0.96
68_N 71_R 1.078 0.95
43_I 51_R 1.059 0.95
71_R 75_Q 1.058 0.95
23_W 37_V 1.006 0.93
73_S 93_G 1.005 0.93
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
1gmxA10.971299.90.269Contact Map0.615
1yt8A10.980899.90.27Contact Map0.706
3tp9A20.980899.90.277Contact Map0.832
3ntdA20.903899.90.277Contact Map0.732
2k0zA10.961599.90.279Contact Map0.571
1qxnA20.980899.90.28Contact Map0.537
3ilmA40.932799.90.281Contact Map0.75
3fojA10.942399.90.284Contact Map0.706
3icsA20.961599.90.285Contact Map0.782
3emeA10.942399.90.286Contact Map0.7

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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