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NUSG - Transcription antitermination protein NusG
UniProt: P0AFG0 Sequence
Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG10667
Length: 181 (176)
Sequences: 1624
Seq/Len: 9.23

NUSG
Paralog alert: 0.28 [within 20: 0.01] - ratio of genomes with paralogs
Cluster includes: NUSG RFAH
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
23_A 27_R 4.699 1.00
105_D 109_D 3.747 1.00
41_E 72_Q 3.63 1.00
38_L 76_N 3.587 1.00
31_K 36_E 3.116 1.00
135_R 179_E 3.052 1.00
158_L 178_V 2.97 1.00
40_G 72_Q 2.838 1.00
48_E 59_K 2.549 1.00
150_E 159_K 2.423 1.00
48_E 61_E 2.163 1.00
132_E 180_K 2.034 1.00
157_R 174_D 2.018 1.00
22_V 89_V 1.878 1.00
47_E 62_R 1.831 1.00
51_E 62_R 1.82 1.00
138_D 177_Q 1.77 1.00
157_R 172_E 1.752 1.00
173_L 177_Q 1.598 1.00
133_M 145_N 1.569 1.00
29_H 86_V 1.548 1.00
73_M 79_S 1.546 1.00
22_V 69_V 1.545 1.00
64_F 70_L 1.536 1.00
130_P 151_V 1.515 1.00
46_T 61_E 1.499 1.00
50_V 57_R 1.48 1.00
73_M 83_V 1.469 1.00
146_G 160_V 1.419 0.99
104_S 107_E 1.401 0.99
129_E 132_E 1.368 0.99
53_R 58_R 1.363 0.99
149_E 161_S 1.349 0.99
18_F 88_R 1.334 0.99
13_Q 90_M 1.315 0.99
135_R 145_N 1.314 0.99
65_F 111_I 1.3 0.99
26_L 83_V 1.295 0.99
7_K 72_Q 1.292 0.99
15_F 18_F 1.267 0.98
50_V 59_K 1.236 0.98
26_L 30_I 1.229 0.98
72_Q 105_D 1.219 0.98
100_P 141_F 1.217 0.98
24_T 28_E 1.21 0.98
135_R 143_D 1.209 0.98
152_D 155_K 1.2 0.98
21_R 24_T 1.194 0.97
14_A 19_E 1.176 0.97
106_K 109_D 1.173 0.97
13_Q 91_G 1.17 0.97
65_F 70_L 1.166 0.97
160_V 173_L 1.163 0.97
80_W 84_R 1.16 0.97
158_L 175_F 1.148 0.97
21_R 25_S 1.131 0.96
49_V 62_R 1.121 0.96
25_S 29_H 1.119 0.96
76_N 79_S 1.112 0.96
173_L 178_V 1.108 0.96
132_E 148_V 1.1 0.95
161_S 168_A 1.096 0.95
30_I 39_F 1.088 0.95
24_T 79_S 1.088 0.95
160_V 170_P 1.072 0.94
93_I 153_Y 1.067 0.94
108_V 112_M 1.057 0.94
22_V 86_V 1.044 0.93
174_D 177_Q 1.043 0.93
11_V 103_I 1.038 0.93
25_S 86_V 1.037 0.93
152_D 172_E 1.037 0.93
94_G 102_P 1.019 0.92
27_R 41_E 1.017 0.92
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
2jvvA10.99451000.086Contact Map0.771
1m1hA10.98341000.132Contact Map0.695
2lq8A10.93371000.146Contact Map0.617
2ougA40.88951000.178Contact Map0.613
2xhcA10.91711000.301Contact Map0.498
3p8bB20.79561000.345Contact Map0.777
1nz8A10.62431000.42Contact Map0.517
3lpeA40.491799.80.595Contact Map0.586
1nz9A10.320499.20.716Contact Map0.77
2e6zA10.32699.10.729Contact Map0.678

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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