| UniProt: | P0ACJ0 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG10547 | ||
| Length: | 164 (151) | ||
| Sequences: | 5595 | ||
| Seq/Len: | 37.05 |
| LRP
Paralog alert: 0.82 [within 20: 0.12] - ratio of genomes with paralogs Cluster includes: ASNC LRP YBAO |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 53_E | 61_Y | 3.716 | 1.00 | |
| 22_E | 37_R | 2.961 | 1.00 | |
| 105_E | 118_K | 2.858 | 1.00 | |
| 68_H | 125_S | 2.799 | 1.00 | |
| 59_Q | 66_N | 2.797 | 1.00 | |
| 112_D | 145_R | 2.675 | 1.00 | |
| 22_E | 29_I | 2.416 | 1.00 | |
| 19_I | 34_L | 2.24 | 1.00 | |
| 31_N | 49_V | 2.24 | 1.00 | |
| 122_P | 126_A | 2.236 | 1.00 | |
| 81_T | 143_D | 2.084 | 1.00 | |
| 59_Q | 64_L | 2.062 | 1.00 | |
| 51_R | 55_Q | 1.964 | 1.00 | |
| 129_K | 133_E | 1.936 | 1.00 | |
| 100_L | 130_L | 1.929 | 1.00 | |
| 40_L | 44_P | 1.92 | 1.00 | |
| 77_F | 107_H | 1.89 | 1.00 | |
| 50_R | 54_R | 1.877 | 1.00 | |
| 126_A | 129_K | 1.876 | 1.00 | |
| 16_D | 48_R | 1.825 | 1.00 | |
| 104_Q | 120_R | 1.813 | 1.00 | |
| 22_E | 25_K | 1.788 | 1.00 | |
| 75_L | 118_K | 1.749 | 1.00 | |
| 83_N | 142_N | 1.705 | 1.00 | |
| 123_D | 126_A | 1.655 | 1.00 | |
| 93_F | 97_V | 1.634 | 1.00 | |
| 29_I | 37_R | 1.609 | 1.00 | |
| 29_I | 34_L | 1.561 | 1.00 | |
| 32_V | 36_K | 1.558 | 1.00 | |
| 23_L | 49_V | 1.552 | 1.00 | |
| 38_V | 45_C | 1.548 | 1.00 | |
| 89_V | 92_Q | 1.505 | 1.00 | |
| 25_K | 37_R | 1.501 | 1.00 | |
| 78_V | 119_T | 1.462 | 1.00 | |
| 26_D | 37_R | 1.451 | 1.00 | |
| 33_E | 36_K | 1.442 | 1.00 | |
| 31_N | 46_L | 1.435 | 1.00 | |
| 128_R | 151_E | 1.389 | 0.99 | |
| 28_R | 61_Y | 1.385 | 0.99 | |
| 13_D | 48_R | 1.379 | 0.99 | |
| 91_E | 95_T | 1.376 | 0.99 | |
| 152_E | 155_Q | 1.375 | 0.99 | |
| 33_E | 37_R | 1.373 | 0.99 | |
| 73_S | 123_D | 1.348 | 0.99 | |
| 41_S | 44_P | 1.311 | 0.99 | |
| 22_E | 34_L | 1.31 | 0.99 | |
| 96_A | 99_K | 1.303 | 0.99 | |
| 32_V | 42_P | 1.299 | 0.99 | |
| 15_I | 40_L | 1.298 | 0.99 | |
| 107_H | 152_E | 1.296 | 0.99 | |
| 80_I | 117_L | 1.266 | 0.99 | |
| 94_N | 151_E | 1.254 | 0.99 | |
| 106_C | 117_L | 1.249 | 0.99 | |
| 102_E | 134_T | 1.24 | 0.98 | |
| 79_E | 147_Y | 1.238 | 0.98 | |
| 102_E | 126_A | 1.236 | 0.98 | |
| 18_N | 21_N | 1.235 | 0.98 | |
| 15_I | 38_V | 1.214 | 0.98 | |
| 72_A | 122_P | 1.181 | 0.98 | |
| 40_L | 45_C | 1.179 | 0.98 | |
| 77_F | 116_L | 1.171 | 0.98 | |
| 94_N | 98_Q | 1.167 | 0.97 | |
| 74_L | 124_M | 1.166 | 0.97 | |
| 31_N | 42_P | 1.152 | 0.97 | |
| 34_L | 49_V | 1.142 | 0.97 | |
| 14_R | 18_N | 1.097 | 0.96 | |
| 27_G | 63_A | 1.096 | 0.96 | |
| 42_P | 46_L | 1.092 | 0.96 | |
| 50_R | 53_E | 1.081 | 0.95 | |
| 96_A | 138_L | 1.078 | 0.95 | |
| 31_N | 35_S | 1.075 | 0.95 | |
| 29_I | 33_E | 1.07 | 0.95 | |
| 28_R | 53_E | 1.07 | 0.95 | |
| 15_I | 18_N | 1.065 | 0.95 | |
| 100_L | 134_T | 1.06 | 0.95 | |
| 30_S | 33_E | 1.055 | 0.95 | |
| 124_M | 148_V | 1.053 | 0.95 | |
| 60_G | 64_L | 1.05 | 0.94 | |
| 18_N | 22_E | 1.039 | 0.94 | |
| 121_V | 126_A | 1.03 | 0.94 | |
| 87_P | 137_R | 1.026 | 0.94 | |
| 92_Q | 96_A | 1.024 | 0.93 | |
| 79_E | 113_F | 1.019 | 0.93 | |
| 95_T | 98_Q | 1.006 | 0.93 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 2e1cA | 1 | 0.9634 | 100 | 0.272 | Contact Map | 0.687 |
| 2p5vA | 8 | 0.9695 | 100 | 0.286 | Contact Map | 0.875 |
| 3i4pA | 1 | 0.9268 | 100 | 0.292 | Contact Map | 0.672 |
| 2cg4A | 2 | 0.9268 | 100 | 0.309 | Contact Map | 0.603 |
| 2ia0A | 2 | 0.9756 | 100 | 0.315 | Contact Map | 0.754 |
| 2pn6A | 1 | 0.8963 | 100 | 0.316 | Contact Map | 0.653 |
| 2gqqA | 4 | 0.9939 | 100 | 0.317 | Contact Map | 0.824 |
| 2cyyA | 1 | 0.9207 | 100 | 0.336 | Contact Map | 0.661 |
| 2dbbA | 2 | 0.9085 | 100 | 0.339 | Contact Map | 0.784 |
| 2w25A | 2 | 0.9085 | 100 | 0.367 | Contact Map | 0.732 |
Sequence Conservation (Image Generated using WebLogo v3)