May 4, 2021 - We are working on upgrading the webserver, some pages may not work.
OPENSEQ.org

GLRX3 - Glutaredoxin-3
UniProt: P0AC62 Sequence
Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG12294
Length: 83 (83)
Sequences: 2794
Seq/Len: 33.66

GLRX3
Paralog alert: 0.70 [within 20: 0.04] - ratio of genomes with paralogs
Cluster includes: GLRX1 GLRX3 NRDH
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
66_C 70_Y 2.991 1.00
23_S 29_F 2.68 1.00
3_N 59_D 2.468 1.00
6_I 56_I 2.059 1.00
33_P 36_G 1.981 1.00
20_A 24_S 1.957 1.00
25_K 73_D 1.866 1.00
17_R 70_Y 1.857 1.00
44_M 53_V 1.79 1.00
10_E 33_P 1.785 1.00
17_R 66_C 1.703 1.00
4_V 27_V 1.64 1.00
5_E 32_L 1.639 1.00
18_A 69_L 1.614 1.00
10_E 35_D 1.6 1.00
25_K 79_D 1.541 1.00
55_Q 62_H 1.498 1.00
18_A 66_C 1.489 1.00
42_E 46_K 1.463 1.00
50_R 55_Q 1.454 1.00
5_E 47_R 1.429 1.00
19_K 31_E 1.39 0.99
40_K 43_E 1.386 0.99
73_D 79_D 1.362 0.99
8_T 31_E 1.345 0.99
79_D 83_K 1.3 0.99
77_G 80_P 1.299 0.99
18_A 56_I 1.297 0.99
58_I 81_L 1.296 0.99
50_R 62_H 1.295 0.99
24_S 73_D 1.294 0.99
6_I 22_L 1.221 0.98
21_L 69_L 1.221 0.98
71_A 75_R 1.187 0.98
43_E 47_R 1.182 0.98
5_E 30_Q 1.18 0.98
58_I 63_I 1.158 0.97
63_I 72_L 1.14 0.97
56_I 69_L 1.131 0.97
73_D 78_L 1.096 0.96
70_Y 74_A 1.072 0.95
48_S 55_Q 1.062 0.95
37_N 40_K 1.025 0.93
72_L 78_L 1.025 0.93
45_I 51_T 1.019 0.93
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
2jadA1199.90.091Contact Map0.599
1u6tA10.975999.80.12Contact Map0.678
2wciA2199.80.161Contact Map0.792
1t1vA2199.80.173Contact Map0.787
2ct6A10.98899.80.18Contact Map0.521
2wemA4199.70.211Contact Map0.726
3gx8A1199.70.216Contact Map0.658
2yanA2199.70.228Contact Map0.864
1wikA1199.70.229Contact Map0.792
3zywA2199.70.232Contact Map0.762

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0526 seconds.