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OPENSEQ.org

GLNK - Nitrogen regulatory protein P-II 2
UniProt: P0AC55 Sequence
Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG12191
Length: 112 (112)
Sequences: 1642
Seq/Len: 14.66

GLNK
Paralog alert: 0.59 [within 20: 0.05] - ratio of genomes with paralogs
Cluster includes: GLNB GLNK
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
98_R 107_A 4.803 1.00
64_A 96_L 4.393 1.00
98_R 108_D 3.548 1.00
65_I 73_V 3.22 1.00
66_A 109_E 2.825 1.00
12_K 15_D 2.45 1.00
16_V 81_A 2.419 1.00
69_Q 72_E 2.412 1.00
6_V 77_V 2.382 1.00
74_I 93_V 2.272 1.00
71_D 75_D 2.1 1.00
78_S 82_Y 2.094 1.00
29_T 33_V 1.97 1.00
3_L 64_A 1.939 1.00
23_I 76_I 1.908 1.00
5_T 94_A 1.901 1.00
66_A 69_Q 1.784 1.00
75_D 79_K 1.748 1.00
13_L 30_V 1.718 1.00
76_I 80_A 1.696 1.00
8_I 16_V 1.527 1.00
72_E 76_I 1.472 1.00
2_K 67_D 1.451 1.00
31_T 62_D 1.425 1.00
4_V 73_V 1.387 0.99
31_T 60_K 1.368 0.99
67_D 109_E 1.274 0.99
65_I 70_L 1.257 0.99
75_D 78_S 1.235 0.98
42_H 54_N 1.202 0.98
39_Q 58_K 1.193 0.98
72_E 75_D 1.164 0.97
1_M 67_D 1.13 0.97
70_L 74_I 1.129 0.97
7_I 29_T 1.084 0.96
3_L 96_L 1.082 0.96
8_I 61_I 1.081 0.95
5_T 60_K 1.075 0.95
5_T 64_A 1.072 0.95
11_F 15_D 1.071 0.95
71_D 98_R 1.057 0.95
101_R 106_E 1.028 0.94
18_E 22_S 1.014 0.93
36_F 55_F 1.002 0.92
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
2o66A311000.175Contact Map0.88
3t9zA611000.175Contact Map0.838
3ncqA311000.185Contact Map0.811
1hwuA611000.196Contact Map0.878
1vfjA311000.198Contact Map0.778
3bzqA111000.201Contact Map0.582
3l7pA611000.203Contact Map0.879
4affA111000.206Contact Map0.765
2ns1B111000.213Contact Map0.65
2j9cA311000.214Contact Map0.816

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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