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OPENSEQ.org

YCCA - Modulator of FtsH protease YccA
UniProt: P0AAC6 Sequence
Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG11113
Length: 219 (208)
Sequences: 1510
Seq/Len: 7.26

YCCA
Paralog alert: 0.29 [within 20: 0.02] - ratio of genomes with paralogs
Cluster includes: YBHL YCCA
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
25_Y 180_T 3.487 1.00
121_S 180_T 3.096 1.00
168_F 208_S 2.901 1.00
53_I 57_V 2.549 1.00
149_M 164_I 2.389 1.00
25_Y 121_S 2.375 1.00
109_A 212_I 2.323 1.00
120_C 173_S 2.249 1.00
135_G 178_F 2.087 1.00
119_C 143_V 2.056 1.00
121_S 125_L 1.994 1.00
167_V 171_I 1.947 1.00
31_T 79_A 1.919 1.00
166_A 212_I 1.916 1.00
179_E 201_S 1.895 1.00
115_L 147_I 1.883 1.00
94_L 106_I 1.874 1.00
109_A 209_L 1.84 1.00
169_I 205_I 1.803 1.00
59_M 86_L 1.801 1.00
112_G 213_L 1.756 1.00
176_I 205_I 1.749 1.00
151_A 155_L 1.74 1.00
35_S 199_Y 1.728 1.00
159_A 163_A 1.681 1.00
23_N 191_Y 1.645 1.00
161_H 211_S 1.626 1.00
207_V 211_S 1.619 1.00
138_L 178_F 1.615 1.00
59_M 89_I 1.607 1.00
179_E 182_N 1.599 1.00
139_M 143_V 1.587 1.00
145_V 168_F 1.559 1.00
200_V 204_N 1.537 1.00
142_I 200_V 1.532 0.99
142_I 146_L 1.525 0.99
29_S 118_F 1.52 0.99
182_N 197_S 1.465 0.99
173_S 205_I 1.459 0.99
143_V 147_I 1.455 0.99
155_L 158_P 1.448 0.99
36_A 111_G 1.446 0.99
179_E 200_V 1.442 0.99
138_L 174_G 1.431 0.99
81_A 85_F 1.428 0.99
74_T 78_S 1.412 0.99
127_T 131_M 1.376 0.99
152_N 155_L 1.365 0.99
182_N 201_S 1.348 0.98
33_A 114_A 1.331 0.98
160_L 164_I 1.298 0.98
61_G 64_F 1.29 0.98
112_G 169_I 1.282 0.98
127_T 181_S 1.271 0.97
146_L 150_V 1.265 0.97
191_Y 194_A 1.26 0.97
40_T 44_V 1.256 0.97
105_V 213_L 1.248 0.97
97_Y 214_G 1.244 0.97
111_G 115_L 1.23 0.97
172_S 204_N 1.228 0.97
172_S 200_V 1.224 0.97
122_A 126_T 1.219 0.96
145_V 171_I 1.219 0.96
65_L 78_S 1.216 0.96
74_T 77_I 1.214 0.96
148_G 164_I 1.211 0.96
108_M 213_L 1.199 0.96
57_V 61_G 1.199 0.96
61_G 65_L 1.199 0.96
163_A 167_V 1.191 0.96
166_A 170_L 1.184 0.96
209_L 213_L 1.18 0.96
112_G 209_L 1.155 0.95
109_A 112_G 1.153 0.95
123_Y 129_K 1.146 0.95
123_Y 127_T 1.14 0.94
197_S 201_S 1.138 0.94
170_L 174_G 1.13 0.94
28_L 198_L 1.108 0.93
137_M 141_G 1.095 0.93
162_L 212_I 1.094 0.93
37_I 41_A 1.087 0.92
39_A 44_V 1.079 0.92
112_G 151_A 1.07 0.91
134_L 138_L 1.055 0.91
131_M 177_L 1.048 0.90
165_S 211_S 1.047 0.90
116_V 120_C 1.043 0.90
124_V 181_S 1.038 0.90
58_G 85_F 1.029 0.89
90_L 207_V 1.028 0.89
55_T 59_M 1.018 0.89
117_F 176_I 1.015 0.88
172_S 179_E 1.014 0.88
69_T 74_T 1 0.87
198_L 201_S 1 0.87
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results:
PDB Chains Cov P(%) HHΔ   Acc
4i0uA100.337913.10.951Contact Map0.463
4ev6A50.328810.10.953Contact Map0.35
2vwaA60.155320.967Contact Map
3arcI20.12331.60.969Contact Map0.697
1pfiA20.20551.40.969Contact Map0.255
1r8hA60.15071.30.97Contact Map
3synE40.09591.20.971Contact Map
3oetA80.33791.20.971Contact Map0.15
1a7gE10.1371.10.972Contact Map
3u5cV10.132410.972Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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