| UniProt: | P0A953 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG10274 | ||
| Length: | 406 (400) | ||
| Sequences: | 10026 | ||
| Seq/Len: | 25.07 |
| FABB
Paralog alert: 0.57 [within 20: 0.25] - ratio of genomes with paralogs Cluster includes: FABB FABF |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 18_N | 21_E | 3.421 | 1.00 | |
| 224_A | 366_E | 3.35 | 1.00 | |
| 98_R | 183_D | 3.306 | 1.00 | |
| 255_A | 347_L | 3.27 | 1.00 | |
| 346_S | 385_V | 3.034 | 1.00 | |
| 24_A | 28_E | 2.981 | 1.00 | |
| 278_V | 315_E | 2.963 | 1.00 | |
| 85_D | 254_Y | 2.938 | 1.00 | |
| 222_Y | 297_S | 2.848 | 1.00 | |
| 258_V | 402_R | 2.789 | 1.00 | |
| 82_A | 239_V | 2.642 | 1.00 | |
| 242_E | 245_H | 2.554 | 1.00 | |
| 170_I | 343_A | 2.51 | 1.00 | |
| 384_T | 402_R | 2.398 | 1.00 | |
| 349_M | 356_A | 2.332 | 1.00 | |
| 60_I | 68_M | 2.309 | 1.00 | |
| 171_G | 260_Y | 2.305 | 1.00 | |
| 224_A | 363_E | 2.303 | 1.00 | |
| 254_Y | 351_E | 2.243 | 1.00 | |
| 102_I | 176_Q | 2.21 | 1.00 | |
| 221_T | 329_A | 2.148 | 1.00 | |
| 177_I | 242_E | 2.146 | 1.00 | |
| 241_E | 251_A | 2.118 | 1.00 | |
| 174_V | 257_I | 2.081 | 1.00 | |
| 343_A | 401_M | 2.078 | 1.00 | |
| 232_A | 334_S | 2.077 | 1.00 | |
| 33_I | 50_G | 2.073 | 1.00 | |
| 6_I | 347_L | 2.072 | 1.00 | |
| 243_L | 404_L | 2.072 | 1.00 | |
| 147_A | 156_N | 2.058 | 1.00 | |
| 278_V | 282_K | 2.051 | 1.00 | |
| 79_M | 186_F | 2.017 | 1.00 | |
| 236_G | 340_V | 1.994 | 1.00 | |
| 78_S | 235_G | 1.984 | 1.00 | |
| 241_E | 249_R | 1.955 | 1.00 | |
| 25_S | 32_G | 1.942 | 1.00 | |
| 292_I | 384_T | 1.928 | 1.00 | |
| 103_A | 237_M | 1.91 | 1.00 | |
| 22_V | 327_T | 1.903 | 1.00 | |
| 105_S | 142_V | 1.891 | 1.00 | |
| 100_G | 185_V | 1.881 | 1.00 | |
| 25_S | 30_R | 1.877 | 1.00 | |
| 238_V | 343_A | 1.871 | 1.00 | |
| 225_H | 363_E | 1.867 | 1.00 | |
| 245_H | 248_A | 1.854 | 1.00 | |
| 6_I | 343_A | 1.849 | 1.00 | |
| 55_D | 58_G | 1.842 | 1.00 | |
| 79_M | 146_L | 1.84 | 1.00 | |
| 27_R | 354_F | 1.838 | 1.00 | |
| 291_P | 384_T | 1.832 | 1.00 | |
| 343_A | 387_S | 1.829 | 1.00 | |
| 3_R | 258_V | 1.824 | 1.00 | |
| 210_K | 227_D | 1.798 | 1.00 | |
| 161_S | 164_A | 1.747 | 1.00 | |
| 182_Q | 185_V | 1.745 | 1.00 | |
| 176_Q | 182_Q | 1.742 | 1.00 | |
| 17_N | 21_E | 1.736 | 1.00 | |
| 383_T | 403_K | 1.733 | 1.00 | |
| 80_E | 84_A | 1.732 | 1.00 | |
| 85_D | 252_H | 1.722 | 1.00 | |
| 186_F | 239_V | 1.707 | 1.00 | |
| 348_L | 352_H | 1.707 | 1.00 | |
| 327_T | 341_Q | 1.705 | 1.00 | |
| 358_S | 361_I | 1.696 | 1.00 | |
| 175_E | 179_L | 1.692 | 1.00 | |
| 13_S | 341_Q | 1.685 | 1.00 | |
| 243_L | 247_L | 1.67 | 1.00 | |
| 223_D | 361_I | 1.669 | 1.00 | |
| 223_D | 362_E | 1.668 | 1.00 | |
| 35_F | 47_H | 1.64 | 1.00 | |
| 225_H | 362_E | 1.628 | 1.00 | |
| 214_T | 217_K | 1.601 | 1.00 | |
| 294_Y | 355_I | 1.569 | 1.00 | |
| 75_A | 146_L | 1.562 | 1.00 | |
| 252_H | 351_E | 1.553 | 1.00 | |
| 353_G | 383_T | 1.539 | 1.00 | |
| 323_A | 355_I | 1.529 | 1.00 | |
| 278_V | 316_V | 1.523 | 1.00 | |
| 144_A | 393_G | 1.52 | 1.00 | |
| 236_G | 344_I | 1.516 | 1.00 | |
| 372_N | 379_D | 1.515 | 1.00 | |
| 280_C | 284_A | 1.511 | 1.00 | |
| 10_G | 78_S | 1.507 | 1.00 | |
| 75_A | 142_V | 1.506 | 1.00 | |
| 170_I | 240_V | 1.498 | 1.00 | |
| 295_L | 313_I | 1.492 | 1.00 | |
| 79_M | 237_M | 1.491 | 1.00 | |
| 168_H | 395_T | 1.482 | 1.00 | |
| 35_F | 48_V | 1.478 | 1.00 | |
| 143_S | 158_S | 1.478 | 1.00 | |
| 98_R | 283_M | 1.474 | 1.00 | |
| 354_F | 378_T | 1.473 | 1.00 | |
| 188_G | 237_M | 1.471 | 1.00 | |
| 294_Y | 325_S | 1.465 | 1.00 | |
| 331_T | 341_Q | 1.453 | 1.00 | |
| 365_D | 368_A | 1.45 | 1.00 | |
| 261_G | 280_C | 1.45 | 1.00 | |
| 2_K | 5_V | 1.446 | 1.00 | |
| 50_G | 232_A | 1.444 | 1.00 | |
| 348_L | 351_E | 1.429 | 1.00 | |
| 31_S | 218_A | 1.426 | 1.00 | |
| 173_A | 187_A | 1.423 | 1.00 | |
| 4_A | 240_V | 1.42 | 1.00 | |
| 104_G | 165_T | 1.42 | 1.00 | |
| 100_G | 182_Q | 1.42 | 1.00 | |
| 329_A | 359_I | 1.419 | 1.00 | |
| 9_L | 19_Q | 1.414 | 1.00 | |
| 260_Y | 399_L | 1.392 | 0.99 | |
| 70_D | 74_Y | 1.391 | 0.99 | |
| 175_E | 178_Q | 1.39 | 0.99 | |
| 78_S | 237_M | 1.388 | 0.99 | |
| 261_G | 284_A | 1.378 | 0.99 | |
| 168_H | 397_A | 1.374 | 0.99 | |
| 353_G | 403_K | 1.372 | 0.99 | |
| 238_V | 340_V | 1.357 | 0.99 | |
| 22_V | 345_Y | 1.351 | 0.99 | |
| 24_A | 30_R | 1.349 | 0.99 | |
| 20_Q | 85_D | 1.347 | 0.99 | |
| 208_S | 220_R | 1.344 | 0.99 | |
| 170_I | 399_L | 1.342 | 0.99 | |
| 83_I | 150_F | 1.327 | 0.99 | |
| 82_A | 237_M | 1.321 | 0.99 | |
| 100_G | 155_V | 1.321 | 0.99 | |
| 310_L | 324_I | 1.314 | 0.99 | |
| 184_I | 239_V | 1.314 | 0.99 | |
| 31_S | 360_N | 1.301 | 0.99 | |
| 258_V | 384_T | 1.298 | 0.99 | |
| 2_K | 244_E | 1.293 | 0.99 | |
| 175_E | 181_K | 1.292 | 0.99 | |
| 157_Y | 172_N | 1.291 | 0.99 | |
| 21_E | 24_A | 1.283 | 0.99 | |
| 89_S | 92_A | 1.278 | 0.99 | |
| 254_Y | 347_L | 1.276 | 0.99 | |
| 388_N | 398_T | 1.272 | 0.99 | |
| 95_N | 151_K | 1.264 | 0.99 | |
| 8_G | 85_D | 1.259 | 0.99 | |
| 355_I | 374_V | 1.253 | 0.99 | |
| 208_S | 227_D | 1.253 | 0.99 | |
| 294_Y | 346_S | 1.252 | 0.99 | |
| 292_I | 400_V | 1.239 | 0.98 | |
| 13_S | 236_G | 1.237 | 0.98 | |
| 263_T | 396_N | 1.236 | 0.98 | |
| 80_E | 149_P | 1.234 | 0.98 | |
| 330_M | 359_I | 1.227 | 0.98 | |
| 2_K | 242_E | 1.226 | 0.98 | |
| 329_A | 358_S | 1.213 | 0.98 | |
| 9_L | 344_I | 1.207 | 0.98 | |
| 223_D | 363_E | 1.204 | 0.98 | |
| 75_A | 103_A | 1.204 | 0.98 | |
| 173_A | 185_V | 1.203 | 0.98 | |
| 153_H | 279_R | 1.199 | 0.98 | |
| 209_T | 227_D | 1.196 | 0.98 | |
| 271_A | 304_V | 1.194 | 0.98 | |
| 40_K | 43_G | 1.193 | 0.98 | |
| 350_L | 401_M | 1.191 | 0.98 | |
| 175_E | 287_G | 1.191 | 0.98 | |
| 103_A | 188_G | 1.186 | 0.98 | |
| 220_R | 225_H | 1.186 | 0.98 | |
| 282_K | 286_H | 1.18 | 0.98 | |
| 310_L | 373_I | 1.173 | 0.98 | |
| 216_E | 227_D | 1.172 | 0.98 | |
| 4_A | 174_V | 1.17 | 0.97 | |
| 386_M | 398_T | 1.17 | 0.97 | |
| 279_R | 283_M | 1.169 | 0.97 | |
| 238_V | 344_I | 1.164 | 0.97 | |
| 183_D | 242_E | 1.161 | 0.97 | |
| 147_A | 264_S | 1.157 | 0.97 | |
| 176_Q | 181_K | 1.157 | 0.97 | |
| 259_G | 287_G | 1.157 | 0.97 | |
| 24_A | 27_R | 1.157 | 0.97 | |
| 317_F | 386_M | 1.154 | 0.97 | |
| 281_M | 316_V | 1.147 | 0.97 | |
| 313_I | 324_I | 1.147 | 0.97 | |
| 263_T | 280_C | 1.142 | 0.97 | |
| 217_K | 362_E | 1.142 | 0.97 | |
| 174_V | 178_Q | 1.141 | 0.97 | |
| 99_V | 184_I | 1.139 | 0.97 | |
| 386_M | 400_V | 1.136 | 0.97 | |
| 83_I | 239_V | 1.134 | 0.97 | |
| 285_M | 292_I | 1.131 | 0.97 | |
| 334_S | 341_Q | 1.13 | 0.97 | |
| 110_P | 117_A | 1.112 | 0.96 | |
| 299_G | 305_G | 1.111 | 0.96 | |
| 11_I | 19_Q | 1.11 | 0.96 | |
| 75_A | 237_M | 1.109 | 0.96 | |
| 357_P | 378_T | 1.107 | 0.96 | |
| 292_I | 317_F | 1.106 | 0.96 | |
| 45_R | 202_D | 1.1 | 0.96 | |
| 243_L | 256_E | 1.091 | 0.96 | |
| 210_K | 216_E | 1.087 | 0.96 | |
| 327_T | 331_T | 1.085 | 0.96 | |
| 350_L | 382_L | 1.078 | 0.95 | |
| 346_S | 350_L | 1.077 | 0.95 | |
| 170_I | 187_A | 1.074 | 0.95 | |
| 299_G | 326_A | 1.073 | 0.95 | |
| 234_G | 334_S | 1.072 | 0.95 | |
| 281_M | 388_N | 1.071 | 0.95 | |
| 20_Q | 24_A | 1.063 | 0.95 | |
| 174_V | 287_G | 1.061 | 0.95 | |
| 373_I | 376_E | 1.056 | 0.95 | |
| 199_C | 231_I | 1.056 | 0.95 | |
| 11_I | 22_V | 1.054 | 0.95 | |
| 18_N | 81_Q | 1.054 | 0.95 | |
| 375_T | 379_D | 1.054 | 0.95 | |
| 156_N | 264_S | 1.054 | 0.95 | |
| 244_E | 247_L | 1.051 | 0.94 | |
| 231_I | 335_L | 1.05 | 0.94 | |
| 293_D | 383_T | 1.048 | 0.94 | |
| 168_H | 262_A | 1.048 | 0.94 | |
| 283_M | 287_G | 1.038 | 0.94 | |
| 159_I | 172_N | 1.03 | 0.94 | |
| 153_H | 275_E | 1.026 | 0.94 | |
| 220_R | 227_D | 1.022 | 0.93 | |
| 27_R | 378_T | 1.019 | 0.93 | |
| 15_I | 32_G | 1.019 | 0.93 | |
| 361_I | 364_L | 1.018 | 0.93 | |
| 33_I | 48_V | 1.016 | 0.93 | |
| 23_L | 352_H | 1.014 | 0.93 | |
| 6_I | 401_M | 1.01 | 0.93 | |
| 177_I | 245_H | 1.01 | 0.93 | |
| 26_L | 348_L | 1.01 | 0.93 | |
| 171_G | 181_K | 1.002 | 0.92 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 2vz8A | 2 | 0.9532 | 100 | 0.007 | Contact Map | 0.763 |
| 3mqdA | 1 | 0.9901 | 100 | 0.101 | Contact Map | 0.785 |
| 4kc5A | 4 | 0.9606 | 100 | 0.107 | Contact Map | 0.841 |
| 2gqdA | 2 | 0.9877 | 100 | 0.107 | Contact Map | 0.744 |
| 4jrmD | 4 | 0.9852 | 100 | 0.109 | Contact Map | 0.781 |
| 3o04A | 1 | 0.9877 | 100 | 0.109 | Contact Map | 0.754 |
| 1e5mA | 1 | 0.9877 | 100 | 0.11 | Contact Map | 0.765 |
| 4jgaA | 2 | 0.9926 | 100 | 0.111 | Contact Map | 0.8 |
| 2hg4A | 6 | 0.9581 | 100 | 0.112 | Contact Map | 0.82 |
| 1ox0A | 1 | 0.9852 | 100 | 0.114 | Contact Map | 0.753 |
Sequence Conservation (Image Generated using WebLogo v3)