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OPENSEQ.org
YFCN - UPF0115 protein YfcN
UniProt: P0A8B2 Sequence
 Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG14117
Length: 183 (175)
Sequences: 645
Seq/Len: 3.69
YFCN
Paralog alert: 0.51 [within 20: 0.00] - ratio of genomes with paralogs
Cluster includes: SMRA YFCN
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
112_L 129_V 3.458 1.00
96_L 115_L 2.64 1.00
162_Y 169_L 2.508 1.00
119_C 127_A 2.35 1.00
83_E 92_Y 2.247 1.00
19_M 22_T 2.027 1.00
143_P 147_A 1.898 1.00
133_H 166_A 1.88 1.00
127_A 170_V 1.722 0.99
96_L 124_V 1.692 0.99
119_C 124_V 1.664 0.99
134_G 138_L 1.651 0.99
10_E 13_A 1.638 0.99
10_E 14_L 1.574 0.98
126_C 171_L 1.559 0.98
130_M 166_A 1.55 0.98
128_C 169_L 1.528 0.98
15_F 19_M 1.504 0.97
159_P 169_L 1.486 0.97
115_L 127_A 1.466 0.97
80_S 83_E 1.419 0.96
103_L 111_E 1.402 0.95
96_L 119_C 1.397 0.95
157_Q 165_D 1.379 0.95
139_K 157_Q 1.376 0.95
154_A 171_L 1.371 0.94
75_V 84_A 1.361 0.94
101_H 108_A 1.346 0.94
79_V 153_M 1.338 0.93
129_V 144_L 1.301 0.92
131_H 151_H 1.298 0.92
156_H 162_Y 1.296 0.92
143_P 157_Q 1.291 0.92
120_R 151_H 1.274 0.91
108_A 138_L 1.25 0.90
147_A 157_Q 1.25 0.90
16_R 23_R 1.248 0.90
116_I 127_A 1.24 0.90
9_E 13_A 1.232 0.89
159_P 162_Y 1.215 0.88
109_K 148_Q 1.212 0.88
137_I 152_V 1.21 0.88
160_K 166_A 1.208 0.88
46_R 49_Q 1.206 0.88
77_P 114_A 1.205 0.88
37_K 40_S 1.203 0.88
13_A 17_Q 1.197 0.87
26_K 152_V 1.193 0.87
23_R 120_R 1.188 0.87
120_R 173_E 1.184 0.86
131_H 155_F 1.183 0.86
95_E 124_V 1.182 0.86
84_A 156_H 1.18 0.86
23_R 98_L 1.179 0.86
72_V 143_P 1.176 0.86
115_L 166_A 1.172 0.86
86_K 92_Y 1.171 0.86
80_S 157_Q 1.163 0.85
127_A 172_I 1.152 0.84
74_Y 131_H 1.149 0.84
118_A 122_E 1.137 0.83
73_K 102_G 1.112 0.81
158_A 164_G 1.101 0.80
22_T 98_L 1.096 0.80
82_F 125_F 1.092 0.80
99_D 108_A 1.088 0.79
80_S 131_H 1.084 0.79
69_E 149_H 1.078 0.79
123_H 174_V 1.073 0.78
96_L 127_A 1.072 0.78
21_G 24_K 1.062 0.77
25_I 124_V 1.054 0.76
106_L 129_V 1.052 0.76
75_V 174_V 1.047 0.76
94_P 159_P 1.047 0.76
38_K 41_E 1.041 0.75
86_K 95_E 1.031 0.74
85_K 139_K 1.03 0.74
30_I 170_V 1.026 0.74
101_H 104_T 1.026 0.74
130_M 168_L 1.02 0.73
96_L 129_V 1.017 0.73
65_L 69_E 1.014 0.72
77_P 155_F 1.009 0.72
169_L 174_V 1.004 0.71
96_L 118_A 1.003 0.71
136_H 139_K 1 0.71
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
3qd7X10.71581000.394Contact Map0.434
2zqeA10.45361000.537Contact Map0.536
2d9iA10.464599.80.637Contact Map0.387
3fauA40.38899.80.661Contact Map0.545
2vkcA10.677699.80.662Contact Map0.457
4gxbB10.09847.50.957Contact Map
2i2cA10.44816.30.959Contact Map0.09
1r88A20.64486.10.959Contact Map0.057
4mqlA10.66125.30.96Contact Map0.074
1dqzA20.64485.10.961Contact Map0.075
Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.
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