| UniProt: | P07117 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG10802 | ||
| Length: | 502 (483) | ||
| Sequences: | 5075 | ||
| Seq/Len: | 10.51 |
| PUTP
Paralog alert: 0.72 [within 20: 0.11] - ratio of genomes with paralogs Cluster includes: ACTP PANF PUTP YIDK |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 436_I | 465_G | 5.396 | 1.00 | |
| 363_R | 370_E | 3.997 | 1.00 | |
| 436_I | 461_F | 3.811 | 1.00 | |
| 367_S | 370_E | 3.769 | 1.00 | |
| 263_S | 266_S | 3.586 | 1.00 | |
| 467_V | 471_L | 3.539 | 1.00 | |
| 425_M | 466_I | 3.231 | 1.00 | |
| 358_Y | 366_A | 3.152 | 1.00 | |
| 465_G | 469_F | 3.098 | 1.00 | |
| 469_F | 473_G | 3.044 | 1.00 | |
| 432_A | 469_F | 3.023 | 1.00 | |
| 172_I | 383_A | 3.022 | 1.00 | |
| 429_G | 470_S | 2.909 | 1.00 | |
| 159_S | 162_T | 2.856 | 1.00 | |
| 440_T | 461_F | 2.788 | 1.00 | |
| 214_D | 217_E | 2.768 | 1.00 | |
| 20_L | 24_I | 2.58 | 1.00 | |
| 426_T | 473_G | 2.532 | 1.00 | |
| 205_V | 291_F | 2.526 | 1.00 | |
| 203_V | 207_I | 2.498 | 1.00 | |
| 433_G | 466_I | 2.489 | 1.00 | |
| 373_W | 377_V | 2.398 | 1.00 | |
| 478_A | 482_K | 2.377 | 1.00 | |
| 377_V | 381_V | 2.29 | 1.00 | |
| 428_N | 473_G | 2.269 | 1.00 | |
| 180_F | 260_A | 2.262 | 1.00 | |
| 168_A | 387_I | 2.232 | 1.00 | |
| 426_T | 429_G | 2.186 | 1.00 | |
| 42_L | 184_S | 2.177 | 1.00 | |
| 34_D | 39_G | 2.177 | 1.00 | |
| 423_S | 485_A | 2.108 | 1.00 | |
| 369_K | 373_W | 2.092 | 1.00 | |
| 418_F | 466_I | 2.087 | 1.00 | |
| 384_L | 388_A | 2.082 | 1.00 | |
| 33_D | 40_R | 2.028 | 1.00 | |
| 165_W | 169_A | 2.022 | 1.00 | |
| 113_Y | 419_S | 2.02 | 1.00 | |
| 358_Y | 363_R | 1.957 | 1.00 | |
| 99_V | 264_H | 1.955 | 1.00 | |
| 366_A | 370_E | 1.951 | 1.00 | |
| 37_L | 40_R | 1.947 | 1.00 | |
| 428_N | 432_A | 1.942 | 1.00 | |
| 415_V | 430_A | 1.932 | 1.00 | |
| 464_I | 468_V | 1.93 | 1.00 | |
| 262_D | 266_S | 1.928 | 1.00 | |
| 422_W | 425_M | 1.927 | 1.00 | |
| 197_A | 333_A | 1.924 | 1.00 | |
| 432_A | 465_G | 1.921 | 1.00 | |
| 363_R | 366_A | 1.915 | 1.00 | |
| 429_G | 433_G | 1.9 | 1.00 | |
| 424_R | 471_L | 1.881 | 1.00 | |
| 16_F | 20_L | 1.852 | 1.00 | |
| 422_W | 467_V | 1.847 | 1.00 | |
| 118_F | 425_M | 1.82 | 1.00 | |
| 115_T | 126_R | 1.807 | 1.00 | |
| 426_T | 470_S | 1.806 | 1.00 | |
| 66_G | 311_E | 1.799 | 1.00 | |
| 422_W | 471_L | 1.788 | 1.00 | |
| 353_I | 378_M | 1.787 | 1.00 | |
| 217_E | 221_Q | 1.763 | 1.00 | |
| 178_G | 182_A | 1.706 | 1.00 | |
| 13_V | 17_G | 1.704 | 1.00 | |
| 353_I | 357_L | 1.701 | 1.00 | |
| 355_E | 359_K | 1.665 | 1.00 | |
| 328_G | 332_S | 1.639 | 1.00 | |
| 213_G | 217_E | 1.627 | 1.00 | |
| 199_I | 203_V | 1.618 | 1.00 | |
| 46_V | 188_T | 1.61 | 1.00 | |
| 265_H | 268_V | 1.605 | 1.00 | |
| 418_F | 463_S | 1.603 | 1.00 | |
| 38_G | 180_F | 1.589 | 1.00 | |
| 468_V | 471_L | 1.587 | 1.00 | |
| 425_M | 429_G | 1.585 | 1.00 | |
| 214_D | 218_V | 1.581 | 1.00 | |
| 218_V | 221_Q | 1.559 | 1.00 | |
| 358_Y | 374_V | 1.559 | 1.00 | |
| 358_Y | 370_E | 1.541 | 1.00 | |
| 378_M | 381_V | 1.54 | 1.00 | |
| 300_P | 304_G | 1.518 | 1.00 | |
| 124_I | 431_L | 1.5 | 1.00 | |
| 439_L | 443_V | 1.499 | 1.00 | |
| 131_L | 135_L | 1.494 | 1.00 | |
| 346_L | 383_A | 1.481 | 1.00 | |
| 428_N | 472_L | 1.452 | 1.00 | |
| 432_A | 436_I | 1.451 | 1.00 | |
| 171_T | 342_L | 1.446 | 1.00 | |
| 411_A | 414_P | 1.445 | 1.00 | |
| 429_G | 469_F | 1.438 | 1.00 | |
| 49_L | 188_T | 1.436 | 1.00 | |
| 54_S | 344_C | 1.433 | 1.00 | |
| 112_D | 356_D | 1.427 | 1.00 | |
| 18_M | 189_V | 1.423 | 1.00 | |
| 424_R | 474_K | 1.414 | 1.00 | |
| 17_G | 189_V | 1.406 | 0.99 | |
| 366_A | 371_L | 1.404 | 0.99 | |
| 107_A | 116_G | 1.401 | 0.99 | |
| 187_D | 257_R | 1.399 | 0.99 | |
| 349_C | 382_V | 1.391 | 0.99 | |
| 5_T | 9_V | 1.39 | 0.99 | |
| 358_Y | 362_L | 1.384 | 0.99 | |
| 435_I | 439_L | 1.384 | 0.99 | |
| 460_I | 464_I | 1.381 | 0.99 | |
| 266_S | 269_H | 1.379 | 0.99 | |
| 47_T | 261_A | 1.372 | 0.99 | |
| 36_I | 375_G | 1.371 | 0.99 | |
| 58_G | 147_A | 1.371 | 0.99 | |
| 190_Q | 343_S | 1.36 | 0.99 | |
| 480_M | 483_R | 1.355 | 0.99 | |
| 292_G | 313_V | 1.354 | 0.99 | |
| 252_P | 256_A | 1.349 | 0.99 | |
| 21_I | 189_V | 1.336 | 0.99 | |
| 8_L | 12_C | 1.33 | 0.99 | |
| 362_L | 366_A | 1.329 | 0.99 | |
| 359_K | 371_L | 1.328 | 0.99 | |
| 17_G | 21_I | 1.328 | 0.99 | |
| 209_V | 215_S | 1.322 | 0.99 | |
| 168_A | 383_A | 1.318 | 0.99 | |
| 370_E | 373_W | 1.318 | 0.99 | |
| 149_A | 164_L | 1.317 | 0.99 | |
| 9_V | 13_V | 1.315 | 0.99 | |
| 186_T | 190_Q | 1.307 | 0.99 | |
| 373_W | 376_R | 1.305 | 0.99 | |
| 68_V | 75_E | 1.301 | 0.99 | |
| 93_V | 417_L | 1.298 | 0.99 | |
| 20_L | 23_F | 1.298 | 0.99 | |
| 470_S | 473_G | 1.29 | 0.99 | |
| 431_L | 435_I | 1.288 | 0.99 | |
| 186_T | 343_S | 1.288 | 0.99 | |
| 482_K | 486_E | 1.273 | 0.99 | |
| 162_T | 165_W | 1.273 | 0.99 | |
| 316_E | 320_I | 1.272 | 0.99 | |
| 117_R | 422_W | 1.266 | 0.99 | |
| 115_T | 360_A | 1.264 | 0.99 | |
| 50_S | 344_C | 1.263 | 0.99 | |
| 366_A | 374_V | 1.263 | 0.99 | |
| 161_E | 165_W | 1.25 | 0.99 | |
| 169_A | 173_L | 1.243 | 0.98 | |
| 118_F | 418_F | 1.236 | 0.98 | |
| 113_Y | 117_R | 1.231 | 0.98 | |
| 301_A | 304_G | 1.231 | 0.98 | |
| 370_E | 374_V | 1.225 | 0.98 | |
| 31_N | 34_D | 1.224 | 0.98 | |
| 171_T | 339_M | 1.221 | 0.98 | |
| 217_E | 220_K | 1.221 | 0.98 | |
| 422_W | 429_G | 1.217 | 0.98 | |
| 265_H | 269_H | 1.213 | 0.98 | |
| 479_A | 483_R | 1.208 | 0.98 | |
| 354_T | 375_G | 1.207 | 0.98 | |
| 44_P | 266_S | 1.205 | 0.98 | |
| 174_Y | 339_M | 1.203 | 0.98 | |
| 150_R | 309_N | 1.202 | 0.98 | |
| 126_R | 356_D | 1.199 | 0.98 | |
| 410_A | 414_P | 1.198 | 0.98 | |
| 7_M | 325_W | 1.189 | 0.98 | |
| 118_F | 419_S | 1.182 | 0.98 | |
| 176_F | 380_L | 1.182 | 0.98 | |
| 296_F | 320_I | 1.18 | 0.98 | |
| 109_T | 351_S | 1.175 | 0.98 | |
| 424_R | 475_A | 1.171 | 0.98 | |
| 463_S | 467_V | 1.171 | 0.98 | |
| 318_A | 330_L | 1.171 | 0.98 | |
| 132_V | 438_A | 1.166 | 0.97 | |
| 426_T | 469_F | 1.166 | 0.97 | |
| 436_I | 440_T | 1.16 | 0.97 | |
| 117_R | 419_S | 1.159 | 0.97 | |
| 54_S | 187_D | 1.159 | 0.97 | |
| 162_T | 166_A | 1.156 | 0.97 | |
| 164_L | 387_I | 1.154 | 0.97 | |
| 467_V | 470_S | 1.151 | 0.97 | |
| 425_M | 470_S | 1.149 | 0.97 | |
| 422_W | 470_S | 1.148 | 0.97 | |
| 433_G | 462_G | 1.14 | 0.97 | |
| 477_S | 480_M | 1.135 | 0.97 | |
| 461_F | 465_G | 1.132 | 0.97 | |
| 429_G | 432_A | 1.12 | 0.96 | |
| 119_E | 427_R | 1.117 | 0.96 | |
| 118_F | 466_I | 1.115 | 0.96 | |
| 136_F | 407_G | 1.11 | 0.96 | |
| 50_S | 54_S | 1.11 | 0.96 | |
| 200_L | 204_I | 1.108 | 0.96 | |
| 57_S | 61_L | 1.1 | 0.96 | |
| 148_G | 167_G | 1.1 | 0.96 | |
| 225_E | 228_D | 1.09 | 0.96 | |
| 183_V | 186_T | 1.085 | 0.96 | |
| 187_D | 343_S | 1.085 | 0.96 | |
| 419_S | 430_A | 1.082 | 0.96 | |
| 165_W | 384_L | 1.082 | 0.96 | |
| 353_I | 382_V | 1.078 | 0.95 | |
| 165_W | 391_A | 1.078 | 0.95 | |
| 307_N | 310_A | 1.077 | 0.95 | |
| 112_D | 355_E | 1.076 | 0.95 | |
| 374_V | 378_M | 1.07 | 0.95 | |
| 153_E | 157_G | 1.068 | 0.95 | |
| 29_T | 34_D | 1.068 | 0.95 | |
| 158_M | 163_A | 1.066 | 0.95 | |
| 122_S | 427_R | 1.059 | 0.95 | |
| 150_R | 153_E | 1.058 | 0.95 | |
| 171_T | 343_S | 1.054 | 0.95 | |
| 465_G | 468_V | 1.052 | 0.95 | |
| 50_S | 257_R | 1.049 | 0.94 | |
| 145_I | 168_A | 1.047 | 0.94 | |
| 57_S | 140_Y | 1.047 | 0.94 | |
| 53_A | 257_R | 1.046 | 0.94 | |
| 175_T | 343_S | 1.042 | 0.94 | |
| 424_R | 427_R | 1.036 | 0.94 | |
| 12_C | 16_F | 1.031 | 0.94 | |
| 174_Y | 343_S | 1.031 | 0.94 | |
| 161_E | 391_A | 1.029 | 0.94 | |
| 174_Y | 182_A | 1.029 | 0.94 | |
| 422_W | 426_T | 1.028 | 0.94 | |
| 140_Y | 252_P | 1.027 | 0.94 | |
| 35_Y | 379_V | 1.027 | 0.94 | |
| 187_D | 344_C | 1.026 | 0.94 | |
| 385_V | 388_A | 1.022 | 0.93 | |
| 14_Y | 336_A | 1.021 | 0.93 | |
| 213_G | 216_L | 1.021 | 0.93 | |
| 50_S | 53_A | 1.019 | 0.93 | |
| 33_D | 106_N | 1.018 | 0.93 | |
| 7_M | 10_T | 1.018 | 0.93 | |
| 468_V | 472_L | 1.018 | 0.93 | |
| 481_Q | 485_A | 1.015 | 0.93 | |
| 210_G | 214_D | 1.014 | 0.93 | |
| 428_N | 469_F | 1.006 | 0.93 | |
| 133_I | 412_F | 1.006 | 0.93 | |
| 190_Q | 336_A | 1.003 | 0.93 | |
| 212_F | 216_L | 1.001 | 0.92 | |
| 427_R | 431_L | 1.001 | 0.92 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 2xq2A | 1 | 0.9761 | 100 | 0.27 | Contact Map | 0.637 |
| 3dh4A | 4 | 0.9323 | 100 | 0.314 | Contact Map | 0.582 |
| 3l1lA | 1 | 0.8466 | 99.3 | 0.872 | Contact Map | 0.386 |
| 3giaA | 1 | 0.8526 | 98.9 | 0.888 | Contact Map | 0.396 |
| 2jlnA | 1 | 0.8625 | 98.4 | 0.907 | Contact Map | 0.395 |
| 4djkA | 2 | 0.8785 | 98 | 0.916 | Contact Map | 0.311 |
| 4c7rA | 3 | 0.8745 | 97.1 | 0.93 | Contact Map | 0.36 |
| 4ainA | 3 | 0.8486 | 96.9 | 0.931 | Contact Map | 0.466 |
| 2wswA | 1 | 0.7968 | 96.1 | 0.937 | Contact Map | 0.329 |
| 4m48A | 1 | 0.8805 | 41.4 | 0.967 | Contact Map | 0.26 |
Sequence Conservation (Image Generated using WebLogo v3)