May 4, 2021 - We are working on upgrading the webserver, some pages may not work.
OPENSEQ.org

HIS5 - HISX
UniProt: P60595 - P06988
Length: 630
Sequences: 681
Seq/Len: 1.10
I_Prob: 0.00

HIS5 - Imidazole glycerol phosphate synthase subunit HisH
Paralog alert: 0.89 [within 20: 0.05] - ratio of genomes with paralogs
Cluster includes: HIS5 PABA
HISX - Histidinol dehydrogenase
Paralog alert: 0.05 [within 20: 0.00] - ratio of genomes with paralogs
Cluster includes: HISX
GREMLIN Results (Scaled_score > 1):

Legend: The darker and larger the blue dots, the higher strength in coevolution.

Residue pairs sorted by strength in coevolution signal:
i j Scaled Score I_Prob
157_C 123_P 1.29 0.00
87_S 257_L 1.20 0.00
88_E 348_V 1.05 0.00
27_P 252_V 0.98 0.00
85_R 249_P 0.97 0.00
36_V 195_F 0.95 0.00
132_G 141_T 0.94 0.00
96_L 66_L 0.94 0.00
183_G 172_A 0.93 0.00
133_I 290_A 0.92 0.00
5_I 103_K 0.91 0.00
53_A 94_N 0.89 0.00
38_L 49_E 0.89 0.00
80_M 422_A 0.87 0.00
136_G 241_V 0.85 0.00
5_I 213_F 0.84 0.00
52_A 117_C 0.83 0.00
29_V 56_A 0.82 0.00
18_S 124_V 0.82 0.00
104_P 382_G 0.81 0.00
4_V 161_S 0.80 0.00
99_I 354_S 0.80 0.00
153_T 138_L 0.79 0.00
97_G 184_V 0.79 0.00
83_L 407_I 0.79 0.00
58_R 75_A 0.78 0.00
169_K 88_M 0.77 0.00
10_C 115_V 0.76 0.00
36_V 409_T 0.76 0.00
85_R 75_A 0.75 0.00
21_A 249_P 0.75 0.00
69_C 305_S 0.75 0.00
35_V 55_S 0.74 0.00
106_M 404_A 0.74 0.00
42_L 55_S 0.74 0.00
29_V 302_L 0.74 0.00
145_Y 280_R 0.73 0.00
38_L 34_R 0.73 0.00
95_L 138_L 0.72 0.00
104_P 398_E 0.72 0.00
54_M 292_L 0.72 0.00
172_F 52_R 0.72 0.00
157_C 86_Q 0.72 0.00
52_A 391_T 0.71 0.00
5_I 241_V 0.71 0.00
174_G 161_S 0.71 0.00
174_G 268_V 0.71 0.00
66_I 272_T 0.71 0.00
133_I 240_L 0.71 0.00
29_V 142_V 0.71 0.00
66_I 353_W 0.71 0.00
104_P 304_A 0.71 0.00
165_A 32_I 0.70 0.00
49_T 266_S 0.70 0.00
7_D 193_L 0.70 0.00
120_R 248_T 0.70 0.00
147_M 246_G 0.70 0.00
96_L 324_G 0.69 0.00
13_L 316_C 0.69 0.00
193_F 205_K 0.69 0.00
93_V 308_I 0.69 0.00
174_G 347_S 0.69 0.00
73_V 342_I 0.69 0.00
113_L 215_T 0.69 0.00
196_M 274_A 0.69 0.00
181_R 228_A 0.69 0.00
172_F 271_L 0.68 0.00
154_I 372_Y 0.68 0.00
91_N 289_L 0.68 0.00
Legend: The i (protein A) and j (protein B) are positions as given in the UniProt sequences. The value of the raw score is the function of the learning procedure, L2 normalization and APC (entropic) correction.

Scaled Score = raw_score/average(raw_scores)
I_Prob = P(contact | scaled_score, seq/len, top_inter_score)

Text file of predictions
(includes both intra and inter preds)

Page generated in 0.1265 seconds.