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OPENSEQ.org

HOLB - KTHY
UniProt: P28631 - P0A720
Length: 547
Sequences: 805
Seq/Len: 1.52
I_Prob: 0.01

HOLB - DNA polymerase III subunit delta'
Paralog alert: 0.69 [within 20: 0.07] - ratio of genomes with paralogs
Cluster includes: HOLB
KTHY - Thymidylate kinase
Paralog alert: 0.03 [within 20: 0.01] - ratio of genomes with paralogs
Cluster includes: KTHY
GREMLIN Results (Scaled_score > 1):

Legend: The darker and larger the blue dots, the higher strength in coevolution.

Residue pairs sorted by strength in coevolution signal:
i j Scaled Score I_Prob
141_F 120_L 1.23 0.01
27_L 75_Y 1.14 0.01
141_F 97_I 1.12 0.01
21_G 139_L 1.09 0.00
293_V 115_I 1.01 0.00
177_S 97_I 0.94 0.00
126_N 78_R 0.94 0.00
256_L 12_E 0.93 0.00
24_H 75_Y 0.92 0.00
106_L 167_F 0.90 0.00
116_D 104_S 0.90 0.00
142_F 170_T 0.89 0.00
183_S 204_V 0.88 0.00
106_L 146_G 0.88 0.00
152_L 12_E 0.87 0.00
217_C 174_Y 0.87 0.00
139_T 107_A 0.86 0.00
81_P 105_T 0.86 0.00
24_H 159_I 0.85 0.00
23_G 101_H 0.85 0.00
170_Q 28_E 0.84 0.00
114_V 17_T 0.84 0.00
255_A 146_G 0.84 0.00
96_V 115_I 0.84 0.00
123_A 11_L 0.84 0.00
276_E 6_I 0.83 0.00
115_T 185_H 0.82 0.00
132_L 43_G 0.82 0.00
215_T 187_I 0.82 0.00
27_L 127_V 0.82 0.00
277_L 69_A 0.82 0.00
67_L 167_F 0.82 0.00
264_Q 204_V 0.82 0.00
204_L 184_I 0.82 0.00
266_T 187_I 0.82 0.00
196_G 160_E 0.81 0.00
280_H 92_N 0.80 0.00
114_V 118_H 0.80 0.00
238_H 195_A 0.79 0.00
110_K 98_G 0.79 0.00
305_G 101_H 0.79 0.00
6_W 167_F 0.79 0.00
38_D 139_L 0.78 0.00
233_L 6_I 0.78 0.00
24_H 104_S 0.78 0.00
300_L 196_V 0.78 0.00
256_L 14_A 0.78 0.00
27_L 98_G 0.77 0.00
140_W 74_F 0.77 0.00
43_A 31_G 0.77 0.00
131_T 160_E 0.77 0.00
111_V 143_P 0.77 0.00
12_E 45_Q 0.76 0.00
111_V 69_A 0.76 0.00
312_I 141_V 0.76 0.00
116_D 75_Y 0.76 0.00
175_W 167_F 0.75 0.00
159_C 150_A 0.75 0.00
192_R 97_I 0.75 0.00
142_F 49_K 0.75 0.00
95_E 168_N 0.75 0.00
113_W 155_E 0.74 0.00
107_G 137_L 0.74 0.00
184_Q 25_E 0.74 0.00
131_T 146_G 0.74 0.00
263_A 195_A 0.74 0.00
89_G 6_I 0.74 0.00
140_W 184_I 0.73 0.00
30_Q 92_N 0.73 0.00
276_E 202_T 0.73 0.00
81_P 101_H 0.73 0.00
145_T 192_P 0.73 0.00
11_F 74_F 0.73 0.00
192_R 20_R 0.73 0.00
71_G 121_A 0.72 0.00
207_G 198_D 0.72 0.00
100_L 127_V 0.72 0.00
36_G 77_A 0.72 0.00
170_Q 195_A 0.72 0.00
102_E 196_V 0.72 0.00
39_A 137_L 0.71 0.00
226_S 61_G 0.71 0.00
7_L 143_P 0.71 0.00
48_L 18_T 0.71 0.00
56_H 204_V 0.71 0.00
91_D 194_E 0.70 0.00
145_T 118_H 0.70 0.00
31_A 103_L 0.70 0.00
27_L 4_K 0.70 0.00
282_S 202_T 0.70 0.00
104_A 161_Q 0.70 0.00
102_E 80_Q 0.70 0.00
177_S 192_P 0.70 0.00
129_L 109_Q 0.70 0.00
184_Q 118_H 0.70 0.00
284_S 172_A 0.69 0.00
168_P 90_L 0.69 0.00
159_C 204_V 0.69 0.00
196_G 105_T 0.69 0.00
170_Q 25_E 0.69 0.00
83_K 193_L 0.69 0.00
22_R 97_I 0.69 0.00
129_L 51_R 0.69 0.00
188_L 174_Y 0.69 0.00
156_R 184_I 0.69 0.00
7_L 54_V 0.68 0.00
202_L 18_T 0.68 0.00
197_S 105_T 0.68 0.00
316_L 18_T 0.68 0.00
Legend: The i (protein A) and j (protein B) are positions as given in the UniProt sequences. The value of the raw score is the function of the learning procedure, L2 normalization and APC (entropic) correction.

Scaled Score = raw_score/average(raw_scores)
I_Prob = P(contact | scaled_score, seq/len, top_inter_score)

Text file of predictions
(includes both intra and inter preds)

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