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OPENSEQ.org

HPPK - PANC
UniProt: P26281 - P31663
Length: 442
Sequences: 397
Seq/Len: 0.90
I_Prob: 0.00

HPPK - 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
Paralog alert: 0.11 [within 20: 0.00] - ratio of genomes with paralogs
Cluster includes: HPPK
PANC - Pantothenate synthetase
Paralog alert: 0.02 [within 20: 0.00] - ratio of genomes with paralogs
Cluster includes: PANC
GREMLIN Results (Scaled_score > 1):

Legend: The darker and larger the blue dots, the higher strength in coevolution.

Residue pairs sorted by strength in coevolution signal:
i j Scaled Score I_Prob
91_G 165_D 1.19 0.00
118_D 177_I 1.17 0.00
95_L 264_L 1.16 0.00
91_G 107_T 1.09 0.00
129_L 112_P 1.09 0.00
95_L 156_L 1.06 0.00
70_L 88_D 1.06 0.00
117_Y 268_W 1.04 0.00
15_P 82_L 1.04 0.00
148_L 160_R 1.03 0.00
54_Y 161_K 1.02 0.00
40_F 212_A 1.01 0.00
90_W 165_D 1.00 0.00
50_D 53_V 1.00 0.00
101_L 139_N 0.98 0.00
131_E 216_Q 0.98 0.00
92_P 128_R 0.98 0.00
90_W 107_T 0.97 0.00
95_L 267_A 0.96 0.00
59_V 235_E 0.95 0.00
91_G 238_F 0.95 0.00
20_N 45_K 0.95 0.00
42_R 82_L 0.94 0.00
91_G 59_P 0.93 0.00
54_Y 21_G 0.93 0.00
44_P 250_T 0.93 0.00
72_N 114_L 0.93 0.00
75_Q 18_R 0.93 0.00
43_T 26_L 0.92 0.00
37_V 75_L 0.92 0.00
99_I 215_L 0.92 0.00
100_M 119_E 0.91 0.00
108_N 90_V 0.91 0.00
10_S 167_G 0.91 0.00
119_M 204_L 0.91 0.00
15_P 240_A 0.90 0.00
53_D 229_A 0.90 0.00
58_A 52_V 0.90 0.00
53_D 264_L 0.90 0.00
92_P 246_R 0.89 0.00
60_A 245_I 0.89 0.00
97_L 112_P 0.89 0.00
130_F 48_A 0.89 0.00
21_A 170_I 0.89 0.00
91_G 174_G 0.89 0.00
113_T 85_R 0.88 0.00
121_N 70_R 0.88 0.00
129_L 215_L 0.88 0.00
54_Y 252_L 0.88 0.00
90_W 59_P 0.87 0.00
90_W 115_S 0.87 0.00
90_W 238_F 0.86 0.00
47_G 175_V 0.85 0.00
48_P 140_L 0.85 0.00
131_E 20_E 0.84 0.00
134_P 75_L 0.83 0.00
60_A 159_I 0.83 0.00
59_V 12_Q 0.83 0.00
99_I 49_D 0.82 0.00
138_F 21_G 0.82 0.00
81_Q 206_K 0.82 0.00
5_Y 205_Y 0.82 0.00
103_G 23_R 0.82 0.00
8_I 6_T 0.81 0.00
114_V 49_D 0.81 0.00
95_L 174_G 0.81 0.00
92_P 75_L 0.81 0.00
6_I 205_Y 0.81 0.00
80_Q 272_A 0.80 0.00
92_P 53_V 0.80 0.00
77_I 26_L 0.80 0.00
25_A 195_A 0.79 0.00
92_P 15_R 0.79 0.00
39_S 139_N 0.79 0.00
30_P 178_M 0.79 0.00
99_I 172_I 0.78 0.00
139_P 229_A 0.78 0.00
43_T 206_K 0.78 0.00
110_E 172_I 0.77 0.00
151_R 215_L 0.77 0.00
53_D 267_A 0.77 0.00
73_H 53_V 0.76 0.00
22_A 51_V 0.76 0.00
64_S 80_E 0.76 0.00
82_G 272_A 0.76 0.00
94_T 92_A 0.76 0.00
114_V 113_G 0.76 0.00
151_R 244_Q 0.75 0.00
41_Y 139_N 0.75 0.00
147_I 177_I 0.75 0.00
18_Q 32_N 0.75 0.00
69_E 83_N 0.75 0.00
117_Y 242_D 0.75 0.00
41_Y 262_V 0.75 0.00
54_Y 110_D 0.75 0.00
106_V 68_L 0.74 0.00
118_D 136_K 0.74 0.00
15_P 237_G 0.74 0.00
60_A 160_R 0.74 0.00
26_L 159_I 0.74 0.00
103_G 194_T 0.74 0.00
114_V 230_G 0.73 0.00
54_Y 13_Q 0.73 0.00
121_N 138_F 0.73 0.00
67_P 133_I 0.73 0.00
110_E 194_T 0.73 0.00
129_L 131_S 0.73 0.00
118_D 60_M 0.73 0.00
8_I 158_L 0.72 0.00
23_L 192_Y 0.72 0.00
75_Q 165_D 0.72 0.00
159_W 242_D 0.72 0.00
44_P 241_D 0.72 0.00
8_I 9_L 0.72 0.00
53_D 17_L 0.72 0.00
31_E 223_D 0.71 0.00
61_L 225_I 0.71 0.00
19_V 81_K 0.71 0.00
34_I 115_S 0.71 0.00
77_I 245_I 0.71 0.00
156_L 160_R 0.71 0.00
37_V 165_D 0.71 0.00
65_L 197_Q 0.71 0.00
90_W 111_V 0.71 0.00
15_P 264_L 0.71 0.00
20_N 160_R 0.70 0.00
4_A 247_D 0.70 0.00
91_G 102_G 0.70 0.00
89_R 172_I 0.70 0.00
75_Q 175_V 0.70 0.00
89_R 115_S 0.70 0.00
Legend: The i (protein A) and j (protein B) are positions as given in the UniProt sequences. The value of the raw score is the function of the learning procedure, L2 normalization and APC (entropic) correction.

Scaled Score = raw_score/average(raw_scores)
I_Prob = P(contact | scaled_score, seq/len, top_inter_score)

Text file of predictions
(includes both intra and inter preds)

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