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OPENSEQ.org
HYPD - HYPE
UniProt: P24192 - P24193
Length: 709
Sequences: 479
Seq/Len: 0.69
I_Prob: 0.00
HYPD - Hydrogenase isoenzymes formation protein HypD
Paralog alert: 0.02 [within 20: 0.00] - ratio of genomes with paralogs
Cluster includes: HYPD 		HYPE - Hydrogenase isoenzymes formation protein HypE
Paralog alert: 0.79 [within 20: 0.16] - ratio of genomes with paralogs
Cluster includes: HYPE SELD THIL
GREMLIN Results (Scaled_score > 1):

Legend: The darker and larger the blue dots, the higher strength in coevolution.

Residue pairs sorted by strength in coevolution signal:
i j Scaled Score I_Prob
13_V 318_Y 1.31 0.00
270_I 196_L 1.17 0.00
257_V 127_I 1.13 0.00
8_R 260_E 1.09 0.00
113_K 251_V 1.08 0.00
309_R 171_L 1.06 0.00
61_V 55_F 1.05 0.00
215_A 172_V 1.04 0.00
346_Q 17_Q 1.03 0.00
236_V 90_I 1.01 0.00
299_Y 159_W 1.01 0.00
235_G 254_A 1.01 0.00
292_G 142_K 0.99 0.00
9_A 152_A 0.99 0.00
335_Q 279_V 0.98 0.00
88_H 113_V 0.97 0.00
300_Q 148_A 0.97 0.00
346_Q 13_Q 0.96 0.00
216_S 289_A 0.94 0.00
241_Q 27_F 0.94 0.00
273_V 288_L 0.94 0.00
167_Q 143_L 0.93 0.00
346_Q 184_L 0.93 0.00
215_A 171_L 0.93 0.00
216_S 111_A 0.92 0.00
140_V 171_L 0.92 0.00
171_F 216_V 0.92 0.00
218_F 251_V 0.92 0.00
224_V 172_V 0.92 0.00
195_A 256_R 0.92 0.00
64_I 259_C 0.92 0.00
113_K 194_G 0.91 0.00
79_I 175_T 0.91 0.00
11_E 107_E 0.91 0.00
158_L 34_E 0.90 0.00
172_F 60_Y 0.90 0.00
245_A 281_R 0.90 0.00
235_G 42_D 0.90 0.00
196_F 27_F 0.90 0.00
53_L 183_I 0.89 0.00
126_M 229_A 0.89 0.00
270_I 307_V 0.89 0.00
33_R 111_A 0.89 0.00
61_V 28_A 0.88 0.00
9_A 165_T 0.88 0.00
322_R 327_P 0.88 0.00
298_D 95_S 0.88 0.00
64_I 90_I 0.88 0.00
104_G 95_S 0.88 0.00
180_P 76_A 0.88 0.00
252_N 266_A 0.87 0.00
364_Y 59_S 0.87 0.00
195_A 327_P 0.86 0.00
115_R 3_N 0.86 0.00
261_A 71_N 0.85 0.00
177_T 227_V 0.85 0.00
112_A 5_Q 0.85 0.00
254_Y 56_S 0.85 0.00
61_V 148_A 0.85 0.00
269_A 56_S 0.85 0.00
14_M 281_R 0.85 0.00
162_K 150_M 0.85 0.00
232_L 244_L 0.85 0.00
151_M 119_T 0.84 0.00
356_S 97_G 0.84 0.00
290_S 216_V 0.84 0.00
53_L 245_S 0.84 0.00
61_V 292_H 0.84 0.00
326_V 328_H 0.84 0.00
246_A 108_T 0.84 0.00
94_C 324_L 0.84 0.00
179_I 185_N 0.83 0.00
205_V 177_G 0.83 0.00
83_V 56_S 0.82 0.00
310_P 137_R 0.82 0.00
232_L 126_A 0.82 0.00
196_F 196_L 0.82 0.00
175_H 192_L 0.81 0.00
297_P 150_M 0.81 0.00
180_P 219_L 0.81 0.00
128_A 290_A 0.81 0.00
61_V 261_L 0.80 0.00
113_K 331_P 0.80 0.00
295_L 53_L 0.80 0.00
88_H 76_A 0.80 0.00
230_L 295_P 0.79 0.00
36_R 182_T 0.79 0.00
237_V 314_L 0.79 0.00
145_L 260_E 0.79 0.00
352_L 316_G 0.79 0.00
64_I 217_K 0.79 0.00
191_N 261_L 0.78 0.00
33_R 20_N 0.78 0.00
53_L 288_L 0.78 0.00
55_Q 327_P 0.78 0.00
133_Q 4_I 0.78 0.00
298_D 249_L 0.78 0.00
294_H 277_I 0.77 0.00
126_M 148_A 0.77 0.00
154_T 222_A 0.77 0.00
107_G 183_I 0.77 0.00
347_T 62_I 0.77 0.00
328_T 303_I 0.77 0.00
111_Q 5_Q 0.77 0.00
177_T 192_L 0.77 0.00
36_R 160_G 0.77 0.00
366_Y 141_D 0.76 0.00
328_T 291_L 0.76 0.00
157_T 14_A 0.76 0.00
240_V 269_F 0.76 0.00
105_K 196_L 0.76 0.00
236_V 93_Y 0.76 0.00
307_H 142_K 0.76 0.00
14_M 153_I 0.76 0.00
359_A 218_A 0.76 0.00
268_Q 197_V 0.76 0.00
186_L 260_E 0.76 0.00
204_M 181_A 0.76 0.00
126_M 244_L 0.75 0.00
299_Y 282_N 0.75 0.00
257_V 244_L 0.75 0.00
236_V 324_L 0.75 0.00
225_A 19_I 0.75 0.00
64_I 307_V 0.75 0.00
50_K 142_K 0.75 0.00
50_K 146_N 0.75 0.00
20_L 4_I 0.75 0.00
351_A 207_I 0.75 0.00
197_L 330_E 0.75 0.00
240_V 219_L 0.75 0.00
275_C 238_C 0.74 0.00
216_S 248_A 0.74 0.00
199_P 161_A 0.74 0.00
182_L 330_E 0.74 0.00
182_L 10_S 0.74 0.00
259_P 100_L 0.74 0.00
125_P 60_Y 0.74 0.00
324_G 170_L 0.74 0.00
300_Q 286_Q 0.74 0.00
366_Y 153_I 0.74 0.00
144_G 160_G 0.74 0.00
115_R 96_C 0.74 0.00
134_E 90_I 0.74 0.00
273_V 219_L 0.74 0.00
39_E 220_R 0.73 0.00
309_R 27_F 0.73 0.00
171_F 22_L 0.73 0.00
335_Q 236_A 0.73 0.00
292_G 78_C 0.73 0.00
123_Y 59_S 0.73 0.00
63_F 327_P 0.73 0.00
99_A 56_S 0.73 0.00
12_Q 244_L 0.73 0.00
56_L 143_L 0.73 0.00
242_Q 320_V 0.72 0.00
266_A 66_F 0.72 0.00
349_F 10_S 0.72 0.00
37_I 162_Q 0.72 0.00
7_Y 22_L 0.72 0.00
131_L 4_I 0.72 0.00
24_A 299_D 0.72 0.00
40_V 219_L 0.72 0.00
272_D 184_L 0.72 0.00
151_M 259_C 0.72 0.00
158_L 117_A 0.72 0.00
119_V 284_A 0.72 0.00
356_S 180_G 0.72 0.00
367_R 232_H 0.72 0.00
145_L 148_A 0.72 0.00
335_Q 104_L 0.71 0.00
331_C 307_V 0.71 0.00
225_A 266_A 0.71 0.00
131_L 305_E 0.71 0.00
11_E 165_T 0.71 0.00
82_C 142_K 0.71 0.00
94_C 232_H 0.71 0.00
107_G 156_N 0.71 0.00
231_D 141_D 0.71 0.00
245_A 290_A 0.71 0.00
122_V 68_P 0.71 0.00
197_L 191_G 0.71 0.00
275_C 127_I 0.71 0.00
194_D 182_T 0.71 0.00
127_D 164_L 0.71 0.00
346_Q 165_T 0.71 0.00
86_A 160_G 0.70 0.00
198_A 146_N 0.70 0.00
197_L 186_L 0.70 0.00
246_A 235_A 0.70 0.00
320_R 320_V 0.70 0.00
7_Y 202_V 0.70 0.00
247_H 282_N 0.70 0.00
Legend: The i (protein A) and j (protein B) are positions as given in the UniProt sequences. The value of the raw score is the function of the learning procedure, L2 normalization and APC (entropic) correction.

Scaled Score = raw_score/average(raw_scores)
I_Prob = P(contact | scaled_score, seq/len, top_inter_score)

Text file of predictions (includes both intra and inter preds)
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