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OPENSEQ.org
CYSH - CYSN
UniProt: P17854 - P23845
Length: 719
Sequences: 657
Seq/Len: 1.01
I_Prob: 0.99
CYSH - Phosphoadenosine phosphosulfate reductase
Paralog alert: 0.67 [within 20: 0.27] - ratio of genomes with paralogs
Cluster includes: CYSH 		CYSN - Sulfate adenylyltransferase subunit 1
Paralog alert: 0.34 [within 20: 0.03] - ratio of genomes with paralogs
Cluster includes: CYSN EFTU1 EFTU2
GREMLIN Results (Scaled_score > 1):

Legend: The darker and larger the blue dots, the higher strength in coevolution. Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on HHsearch results which uses the overall probability and per-site alignment confidence. Inter-chain contacts in the pdb are in shades of red.
1zunB:AContact Map


 Residue pairs sorted by strength in coevolution signal:
i j Scaled Score I_Prob
43_N 358_K 2.95 0.99
66_N 295_F 1.69 0.77
141_N 359_I 1.15 0.27
43_N 363_K 1.14 0.26
169_V 280_V 1.12 0.25
61_S 79_A 1.07 0.20
89_F 207_A 1.05 0.19
177_F 56_E 1.04 0.18
59_A 10_A 1.03 0.17
33_A 283_S 1.02 0.17
109_S 154_I 1.01 0.16
34_E 296_D 1.01 0.16
75_I 324_L 0.99 0.15
81_Y 148_T 0.95 0.12
108_E 200_I 0.94 0.12
59_A 229_L 0.93 0.11
92_E 357_I 0.91 0.10
96_K 366_A 0.91 0.10
221_W 203_V 0.91 0.10
177_F 154_I 0.88 0.09
135_N 154_I 0.88 0.09
66_N 154_I 0.85 0.08
145_K 318_I 0.85 0.08
143_A 295_F 0.85 0.08
96_K 246_M 0.85 0.08
188_R 390_L 0.85 0.08
133_D 208_L 0.84 0.07
232_F 193_Q 0.83 0.07
203_P 300_E 0.83 0.07
41_L 155_S 0.83 0.07
190_I 290_A 0.83 0.07
118_G 349_L 0.82 0.07
85_E 164_V 0.82 0.07
206_D 274_V 0.82 0.07
134_I 154_I 0.81 0.07
44_L 318_I 0.81 0.07
209_Y 358_K 0.81 0.07
99_L 205_L 0.81 0.06
198_G 234_T 0.81 0.06
221_W 17_A 0.80 0.06
150_Q 148_T 0.80 0.06
98_K 227_T 0.79 0.06
35_G 130_T 0.79 0.06
74_V 138_I 0.78 0.06
65_V 380_L 0.78 0.05
41_L 133_L 0.78 0.05
89_F 79_A 0.78 0.05
145_K 324_L 0.77 0.05
200_K 246_M 0.77 0.05
74_V 200_I 0.77 0.05
190_I 273_E 0.76 0.05
77_T 217_S 0.76 0.05
148_N 305_G 0.76 0.05
195_Q 160_I 0.75 0.05
109_S 44_I 0.75 0.05
41_L 235_V 0.75 0.05
37_V 358_K 0.75 0.05
88_R 303_F 0.75 0.05
66_N 307_A 0.75 0.05
169_V 62_L 0.75 0.05
66_N 404_L 0.75 0.05
87_Y 339_V 0.75 0.05
40_A 426_N 0.74 0.05
204_L 51_T 0.74 0.05
61_S 155_S 0.74 0.04
92_E 239_R 0.74 0.04
215_T 365_R 0.74 0.04
92_E 182_R 0.74 0.04
61_S 271_R 0.73 0.04
41_L 240_V 0.73 0.04
47_E 272_V 0.73 0.04
130_K 111_I 0.73 0.04
47_E 316_I 0.73 0.04
134_I 33_C 0.73 0.04
109_S 266_T 0.73 0.04
74_V 311_V 0.72 0.04
148_N 352_G 0.72 0.04
86_T 424_L 0.72 0.04
192_Q 346_E 0.72 0.04
88_R 184_R 0.72 0.04
198_G 106_K 0.72 0.04
169_V 429_V 0.72 0.04
102_K 205_L 0.72 0.04
221_W 138_I 0.72 0.04
63_H 307_A 0.72 0.04
92_E 348_P 0.72 0.04
31_L 189_T 0.71 0.04
41_L 252_Y 0.71 0.04
182_I 105_E 0.71 0.04
203_P 167_I 0.71 0.04
66_N 176_S 0.71 0.04
84_P 161_K 0.71 0.04
96_K 238_Q 0.71 0.04
209_Y 355_Y 0.70 0.04
104_Y 324_L 0.70 0.04
198_G 192_G 0.70 0.04
84_P 371_I 0.70 0.04
174_R 100_R 0.70 0.04
198_G 328_D 0.69 0.04
42_D 55_Y 0.69 0.04
75_I 187_Y 0.69 0.04
60_V 311_V 0.69 0.03
96_K 359_I 0.69 0.03
59_A 14_G 0.69 0.03
54_F 152_S 0.69 0.03
77_T 385_V 0.69 0.03
Legend: The i (protein A) and j (protein B) are positions as given in the UniProt sequences. The value of the raw score is the function of the learning procedure, L2 normalization and APC (entropic) correction.

Scaled Score = raw_score/average(raw_scores)
I_Prob = P(contact | scaled_score, seq/len, top_inter_score)

Text file of predictions (includes both intra and inter preds)
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