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OPENSEQ.org

DHPS - HPPK
UniProt: P0AC13 - P26281
Length: 441
Sequences: 552
Seq/Len: 1.28
I_Prob: 0.00

DHPS - Dihydropteroate synthase
Paralog alert: 0.13 [within 20: 0.01] - ratio of genomes with paralogs
Cluster includes: DHPS
HPPK - 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
Paralog alert: 0.11 [within 20: 0.00] - ratio of genomes with paralogs
Cluster includes: HPPK
GREMLIN Results (Scaled_score > 1):

Legend: The darker and larger the blue dots, the higher strength in coevolution.

Residue pairs sorted by strength in coevolution signal:
i j Scaled Score I_Prob
95_V 102_F 1.11 0.00
183_L 100_M 1.01 0.00
102_V 74_T 0.96 0.00
191_G 119_M 0.95 0.00
85_I 40_F 0.90 0.00
75_L 22_A 0.86 0.00
139_M 47_G 0.85 0.00
172_C 46_L 0.84 0.00
267_R 102_F 0.84 0.00
120_L 44_P 0.83 0.00
38_I 50_D 0.82 0.00
129_A 144_L 0.81 0.00
165_F 34_I 0.81 0.00
260_K 19_V 0.80 0.00
177_I 111_R 0.79 0.00
137_C 42_R 0.78 0.00
42_K 149_H 0.78 0.00
182_L 67_P 0.77 0.00
199_S 58_A 0.77 0.00
95_V 45_P 0.77 0.00
254_I 19_V 0.76 0.00
57_V 37_V 0.76 0.00
148_M 54_Y 0.76 0.00
85_I 127_W 0.76 0.00
184_L 4_A 0.75 0.00
21_L 81_Q 0.75 0.00
141_M 129_L 0.75 0.00
252_H 129_L 0.75 0.00
214_L 99_I 0.74 0.00
35_N 66_A 0.73 0.00
21_L 132_I 0.73 0.00
167_E 77_I 0.73 0.00
207_F 130_F 0.73 0.00
200_L 144_L 0.72 0.00
69_V 4_A 0.72 0.00
152_P 105_E 0.72 0.00
137_C 13_A 0.71 0.00
48_I 23_L 0.71 0.00
148_M 22_A 0.70 0.00
160_E 43_T 0.70 0.00
180_E 40_F 0.70 0.00
119_S 101_L 0.69 0.00
249_Q 114_V 0.69 0.00
207_F 59_V 0.69 0.00
102_V 95_L 0.68 0.00
14_H 21_A 0.68 0.00
16_H 148_L 0.68 0.00
234_E 15_P 0.67 0.00
261_E 84_V 0.67 0.00
148_M 46_L 0.67 0.00
57_V 12_L 0.67 0.00
223_M 117_Y 0.66 0.00
143_G 22_A 0.66 0.00
157_V 46_L 0.66 0.00
107_A 68_E 0.66 0.00
59_G 85_R 0.65 0.00
91_V 34_I 0.65 0.00
182_L 12_L 0.65 0.00
31_G 85_R 0.65 0.00
177_I 135_E 0.65 0.00
164_Y 129_L 0.65 0.00
79_I 55_L 0.65 0.00
254_I 29_I 0.65 0.00
234_E 70_L 0.64 0.00
172_C 58_A 0.64 0.00
72_E 72_N 0.64 0.00
218_M 118_D 0.64 0.00
90_E 114_V 0.64 0.00
213_P 46_L 0.64 0.00
75_L 67_P 0.64 0.00
Legend: The i (protein A) and j (protein B) are positions as given in the UniProt sequences. The value of the raw score is the function of the learning procedure, L2 normalization and APC (entropic) correction.

Scaled Score = raw_score/average(raw_scores)
I_Prob = P(contact | scaled_score, seq/len, top_inter_score)

Text file of predictions
(includes both intra and inter preds)

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