May 4, 2021 - We are working on upgrading the webserver, some pages may not work.
OPENSEQ.org
CYOB - CYOC
UniProt: P0ABI8 - P0ABJ3
Length: 867
Sequences: 1336
Seq/Len: 1.67
I_Prob: 0.99
CYOB - Ubiquinol oxidase subunit 1
Paralog alert: 0.25 [within 20: 0.01] - ratio of genomes with paralogs
Cluster includes: CYOB 		CYOC - Cytochrome o ubiquinol oxidase subunit 3
Paralog alert: 0.19 [within 20: 0.04] - ratio of genomes with paralogs
Cluster includes: CYOC
GREMLIN Results (Scaled_score > 1):

Legend: The darker and larger the blue dots, the higher strength in coevolution. Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on HHsearch results which uses the overall probability and per-site alignment confidence. Inter-chain contacts in the pdb are in shades of red.
1fftAF:CHContact Map
1v54AN:CPContact Map


 Residue pairs sorted by strength in coevolution signal:
i j Scaled Score I_Prob
248_V 42_I 2.67 0.99
252_L 137_S 1.62 0.85
259_L 130_P 1.42 0.73
322_C 192_I 1.11 0.41
479_M 197_V 1.10 0.41
433_F 164_I 1.04 0.34
255_L 141_A 1.00 0.30
302_A 113_I 0.98 0.28
213_L 94_N 0.94 0.23
435_G 74_F 0.93 0.23
305_F 42_I 0.93 0.23
373_G 170_T 0.92 0.22
452_W 74_F 0.92 0.22
58_G 150_V 0.90 0.21
471_L 107_L 0.90 0.20
383_W 109_G 0.89 0.20
233_L 41_S 0.89 0.19
210_V 27_F 0.88 0.18
491_F 133_S 0.88 0.18
259_L 133_S 0.87 0.18
500_S 158_A 0.86 0.17
137_A 109_G 0.86 0.17
468_F 120_F 0.86 0.17
49_L 110_A 0.86 0.17
548_P 114_G 0.86 0.17
386_G 60_G 0.86 0.17
375_I 42_I 0.85 0.17
198_G 153_G 0.85 0.17
325_V 164_I 0.85 0.16
252_L 43_L 0.84 0.16
325_V 158_A 0.84 0.16
538_T 48_A 0.84 0.16
198_G 150_V 0.84 0.16
525_Q 97_Q 0.82 0.15
422_N 36_D 0.82 0.15
224_K 181_S 0.82 0.14
465_F 36_D 0.82 0.14
508_G 104_L 0.82 0.14
376_V 81_I 0.81 0.14
203_L 181_S 0.80 0.13
472_Y 116_E 0.80 0.13
466_V 158_A 0.80 0.13
393_V 159_V 0.80 0.13
222_M 27_F 0.80 0.13
552_F 122_H 0.80 0.13
443_A 110_A 0.80 0.13
306_S 74_F 0.80 0.13
381_M 63_I 0.79 0.13
209_F 192_I 0.79 0.13
555_V 41_S 0.78 0.12
205_G 179_C 0.78 0.12
233_L 78_F 0.78 0.12
632_E 167_R 0.78 0.12
630_F 162_V 0.78 0.12
644_E 204_M 0.77 0.12
225_M 92_K 0.77 0.11
497_I 30_W 0.77 0.11
301_I 82_T 0.77 0.11
208_F 193_C 0.77 0.11
539_L 74_F 0.77 0.11
378_H 127_G 0.77 0.11
507_L 110_A 0.76 0.11
199_I 107_L 0.76 0.11
350_I 192_I 0.76 0.11
306_S 106_W 0.76 0.11
444_F 135_F 0.76 0.11
454_K 186_F 0.76 0.11
367_L 141_A 0.76 0.11
291_I 134_G 0.76 0.10
204_T 145_T 0.76 0.10
249_T 38_I 0.76 0.10
336_F 109_G 0.75 0.10
432_C 157_M 0.75 0.10
262_H 117_I 0.75 0.10
81_S 121_H 0.75 0.10
318_W 38_I 0.75 0.10
476_F 147_G 0.75 0.10
304_T 68_F 0.75 0.10
54_H 109_G 0.75 0.10
496_M 114_G 0.74 0.10
399_V 75_L 0.74 0.10
176_L 186_F 0.74 0.10
539_L 166_R 0.74 0.10
402_A 155_I 0.74 0.10
100_D 36_D 0.74 0.10
226_P 148_L 0.74 0.10
374_R 74_F 0.74 0.10
199_I 110_A 0.74 0.10
459_F 34_M 0.74 0.10
516_M 98_V 0.73 0.10
640_V 204_M 0.73 0.09
85_L 113_I 0.73 0.09
393_V 117_I 0.73 0.09
100_D 119_E 0.73 0.09
200_G 140_F 0.73 0.09
216_R 48_A 0.73 0.09
177_S 86_A 0.73 0.09
455_R 162_V 0.73 0.09
71_R 158_A 0.73 0.09
497_I 56_G 0.73 0.09
216_R 42_I 0.72 0.09
297_V 100_S 0.72 0.09
61_Y 147_G 0.72 0.09
542_A 41_S 0.72 0.09
638_V 21_A 0.72 0.09
370_M 134_G 0.72 0.09
502_A 126_N 0.72 0.09
556_P 129_G 0.72 0.09
371_Y 38_I 0.72 0.09
418_A 33_L 0.71 0.08
463_G 65_E 0.71 0.08
534_W 86_A 0.71 0.08
Legend: The i (protein A) and j (protein B) are positions as given in the UniProt sequences. The value of the raw score is the function of the learning procedure, L2 normalization and APC (entropic) correction.

Scaled Score = raw_score/average(raw_scores)
I_Prob = P(contact | scaled_score, seq/len, top_inter_score)

Text file of predictions (includes both intra and inter preds)
Page generated in 0.0675 seconds.