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OPENSEQ.org

KTHY - YCEG
UniProt: P0A720 - P28306
Length: 553
Sequences: 376
Seq/Len: 0.69
I_Prob: 0.00

KTHY - Thymidylate kinase
Paralog alert: 0.03 [within 20: 0.01] - ratio of genomes with paralogs
Cluster includes: KTHY
YCEG - UPF0755 protein YceG
Paralog alert: 0.01 [within 20: 0.00] - ratio of genomes with paralogs
Cluster includes: YCEG
GREMLIN Results (Scaled_score > 1):

Legend: The darker and larger the blue dots, the higher strength in coevolution.

Residue pairs sorted by strength in coevolution signal:
i j Scaled Score I_Prob
12_E 224_E 1.38 0.00
189_A 308_A 1.35 0.00
12_E 314_H 1.33 0.00
196_V 168_Y 1.29 0.00
98_G 146_A 1.28 0.00
65_I 171_N 1.28 0.00
141_V 139_D 1.28 0.00
121_A 204_D 1.25 0.00
146_G 314_H 1.23 0.00
18_T 204_D 1.22 0.00
186_T 322_S 1.21 0.00
98_G 115_V 1.21 0.00
146_G 224_E 1.20 0.00
14_A 234_N 1.18 0.00
47_A 268_P 1.16 0.00
50_L 261_S 1.14 0.00
120_L 68_V 1.13 0.00
137_L 228_V 1.13 0.00
106_Q 49_G 1.12 0.00
104_S 234_N 1.11 0.00
142_T 164_D 1.10 0.00
25_E 191_S 1.09 0.00
25_E 199_G 1.07 0.00
194_E 190_D 1.07 0.00
23_V 57_L 1.06 0.00
143_P 234_N 1.06 0.00
71_V 314_H 1.06 0.00
86_I 330_Y 1.05 0.00
192_P 12_L 1.04 0.00
115_I 133_I 1.04 0.00
26_T 44_L 1.04 0.00
164_F 11_L 1.03 0.00
79_V 234_N 1.03 0.00
145_V 325_K 1.02 0.00
145_V 16_G 1.02 0.00
114_G 185_M 1.02 0.00
71_V 224_E 1.01 0.00
19_A 168_Y 1.01 0.00
18_T 114_L 1.01 0.00
29_Q 139_D 0.99 0.00
162_E 69_F 0.99 0.00
199_A 12_L 0.99 0.00
116_D 300_K 0.98 0.00
150_A 224_E 0.98 0.00
129_G 271_Y 0.98 0.00
65_I 254_E 0.98 0.00
18_T 113_R 0.97 0.00
176_E 145_V 0.95 0.00
12_E 234_N 0.95 0.00
79_V 314_H 0.95 0.00
121_A 254_E 0.95 0.00
150_A 314_H 0.95 0.00
187_I 215_I 0.95 0.00
190_T 120_L 0.94 0.00
182_K 207_Q 0.94 0.00
80_Q 127_L 0.93 0.00
131_F 122_D 0.93 0.00
169_R 196_R 0.93 0.00
187_I 14_V 0.92 0.00
191_Q 267_T 0.92 0.00
127_V 207_Q 0.92 0.00
49_K 288_G 0.92 0.00
45_Q 166_W 0.92 0.00
30_L 20_G 0.92 0.00
145_V 15_L 0.92 0.00
158_R 44_L 0.92 0.00
54_V 215_I 0.92 0.00
71_V 74_R 0.92 0.00
179_A 30_A 0.92 0.00
105_T 288_G 0.91 0.00
74_F 208_L 0.91 0.00
204_V 14_V 0.91 0.00
97_I 17_I 0.91 0.00
29_Q 197_A 0.91 0.00
187_I 129_E 0.90 0.00
114_G 197_A 0.90 0.00
145_V 100_K 0.90 0.00
110_G 225_R 0.90 0.00
23_V 292_L 0.90 0.00
21_N 322_S 0.89 0.00
3_S 119_R 0.89 0.00
21_N 92_Q 0.89 0.00
120_L 301_T 0.89 0.00
47_A 276_I 0.89 0.00
174_Y 264_D 0.88 0.00
172_A 14_V 0.88 0.00
28_E 308_A 0.88 0.00
63_E 286_T 0.88 0.00
101_H 110_F 0.88 0.00
35_M 322_S 0.88 0.00
18_T 153_N 0.87 0.00
17_T 113_R 0.87 0.00
141_V 234_N 0.87 0.00
7_V 288_G 0.86 0.00
17_T 262_R 0.86 0.00
17_T 82_F 0.86 0.00
126_A 276_I 0.86 0.00
46_L 244_T 0.86 0.00
196_V 285_A 0.86 0.00
44_T 265_L 0.86 0.00
166_F 248_V 0.86 0.00
82_V 69_F 0.86 0.00
163_S 287_P 0.86 0.00
106_Q 136_T 0.86 0.00
79_V 86_T 0.86 0.00
12_E 221_V 0.85 0.00
84_T 228_V 0.85 0.00
148_K 215_I 0.85 0.00
159_I 110_F 0.84 0.00
192_P 89_F 0.84 0.00
205_T 198_D 0.84 0.00
12_E 108_A 0.83 0.00
120_L 86_T 0.83 0.00
146_G 188_A 0.83 0.00
1_M 291_S 0.83 0.00
202_T 223_S 0.83 0.00
118_H 10_L 0.83 0.00
50_L 234_N 0.83 0.00
32_I 151_L 0.83 0.00
19_A 234_N 0.82 0.00
141_V 233_I 0.82 0.00
101_H 326_S 0.82 0.00
47_A 43_T 0.82 0.00
47_A 326_S 0.82 0.00
205_T 15_L 0.81 0.00
137_L 106_K 0.81 0.00
185_H 292_L 0.81 0.00
179_A 10_L 0.81 0.00
8_I 82_F 0.81 0.00
127_V 309_D 0.81 0.00
142_T 45_K 0.81 0.00
6_I 43_T 0.81 0.00
133_P 164_D 0.81 0.00
184_I 303_Y 0.81 0.00
22_V 34_L 0.81 0.00
199_A 22_G 0.80 0.00
192_P 190_D 0.80 0.00
12_E 276_I 0.80 0.00
23_V 75_I 0.80 0.00
73_M 95_V 0.80 0.00
1_M 183_K 0.80 0.00
79_V 224_E 0.80 0.00
73_M 208_L 0.80 0.00
82_V 262_R 0.80 0.00
8_I 291_S 0.80 0.00
165_D 194_E 0.80 0.00
73_M 160_W 0.79 0.00
83_E 44_L 0.79 0.00
75_Y 86_T 0.79 0.00
95_W 207_Q 0.79 0.00
131_F 126_Q 0.79 0.00
67_D 168_Y 0.79 0.00
195_A 23_V 0.79 0.00
119_M 146_A 0.78 0.00
14_A 303_Y 0.78 0.00
18_T 286_T 0.78 0.00
113_R 244_T 0.78 0.00
154_G 224_E 0.78 0.00
200_I 267_T 0.78 0.00
175_L 32_S 0.78 0.00
187_I 196_R 0.78 0.00
22_V 228_V 0.78 0.00
203_T 34_L 0.78 0.00
180_Q 291_S 0.78 0.00
1_M 134_K 0.78 0.00
190_T 82_F 0.78 0.00
92_N 190_D 0.78 0.00
115_I 160_W 0.78 0.00
145_V 8_I 0.77 0.00
105_T 221_V 0.77 0.00
193_L 297_H 0.77 0.00
192_P 59_A 0.77 0.00
141_V 64_N 0.77 0.00
148_K 148_A 0.77 0.00
120_L 308_A 0.77 0.00
14_A 324_N 0.77 0.00
53_L 178_L 0.77 0.00
92_N 211_M 0.77 0.00
68_K 311_K 0.77 0.00
186_T 72_L 0.77 0.00
116_D 292_L 0.77 0.00
27_L 289_A 0.77 0.00
192_P 92_Q 0.76 0.00
179_A 49_G 0.76 0.00
29_Q 31_D 0.76 0.00
188_D 239_G 0.76 0.00
45_Q 75_I 0.76 0.00
151_R 271_Y 0.76 0.00
35_M 275_T 0.76 0.00
133_P 288_G 0.76 0.00
97_I 127_L 0.76 0.00
172_A 13_V 0.76 0.00
135_L 286_T 0.76 0.00
174_Y 180_R 0.76 0.00
98_G 320_L 0.76 0.00
121_A 11_L 0.76 0.00
154_G 314_H 0.76 0.00
12_E 188_A 0.76 0.00
101_H 123_Y 0.76 0.00
172_A 15_L 0.75 0.00
175_L 229_A 0.75 0.00
147_L 241_R 0.75 0.00
122_T 29_L 0.75 0.00
11_L 77_P 0.75 0.00
198_D 4_V 0.75 0.00
135_L 185_M 0.75 0.00
165_D 204_D 0.75 0.00
29_Q 13_V 0.75 0.00
52_S 202_Y 0.75 0.00
208_V 20_G 0.75 0.00
202_T 207_Q 0.75 0.00
164_F 275_T 0.75 0.00
163_S 30_A 0.75 0.00
141_V 94_T 0.75 0.00
71_V 210_T 0.75 0.00
Legend: The i (protein A) and j (protein B) are positions as given in the UniProt sequences. The value of the raw score is the function of the learning procedure, L2 normalization and APC (entropic) correction.

Scaled Score = raw_score/average(raw_scores)
I_Prob = P(contact | scaled_score, seq/len, top_inter_score)

Text file of predictions
(includes both intra and inter preds)

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