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IF3 - SYFA
UniProt: P0A707 - P08312
Length: 507
Sequences: 478
Seq/Len: 0.97
I_Prob: 0.02

IF3 - Translation initiation factor IF-3
Paralog alert: 0.02 [within 20: 0.00] - ratio of genomes with paralogs
Cluster includes: IF3
SYFA - Phenylalanine--tRNA ligase alpha subunit
Paralog alert: 0.01 [within 20: 0.00] - ratio of genomes with paralogs
Cluster includes: SYFA
GREMLIN Results (Scaled_score > 1):

Legend: The darker and larger the blue dots, the higher strength in coevolution. Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on HHsearch results which uses the overall probability and per-site alignment confidence. Inter-chain contacts in the pdb are in shades of red.
3pcoAC:BDContact Map
1b7yA:BContact Map


Residue pairs sorted by strength in coevolution signal:
i j Scaled Score I_Prob
89_K 276_H 1.51 0.02
98_F 64_K 1.49 0.02
85_K 220_F 1.40 0.01
134_E 204_P 1.26 0.01
75_Y 68_Q 1.25 0.01
56_I 133_I 1.22 0.01
68_M 11_A 1.22 0.01
86_K 29_V 1.21 0.01
44_E 71_L 1.20 0.01
86_K 35_K 1.17 0.01
119_E 4_L 1.13 0.01
103_D 56_A 1.13 0.01
107_Y 272_C 1.11 0.01
102_T 200_Q 1.10 0.01
140_I 16_S 1.10 0.01
152_L 183_P 1.07 0.01
91_I 18_A 1.07 0.01
61_E 5_A 1.07 0.01
66_R 58_A 1.06 0.01
97_K 312_L 1.05 0.01
99_R 205_M 1.04 0.01
97_K 204_P 1.03 0.01
43_L 180_A 1.03 0.01
112_R 96_L 1.03 0.01
79_K 36_G 1.03 0.01
68_M 322_F 1.02 0.01
70_Y 217_N 1.01 0.01
148_V 312_L 0.99 0.00
99_R 204_P 0.99 0.00
122_D 304_M 0.96 0.00
67_I 32_L 0.96 0.00
154_E 58_A 0.95 0.00
129_R 185_I 0.95 0.00
109_V 267_L 0.94 0.00
56_I 241_I 0.94 0.00
154_E 4_L 0.94 0.00
111_L 315_F 0.93 0.00
79_K 307_Y 0.93 0.00
82_K 198_Y 0.93 0.00
67_I 257_V 0.93 0.00
80_S 148_H 0.93 0.00
140_I 92_I 0.93 0.00
34_L 218_I 0.92 0.00
66_R 180_A 0.91 0.00
166_E 71_L 0.91 0.00
177_K 110_T 0.91 0.00
56_I 60_I 0.91 0.00
169_Q 236_E 0.90 0.00
170_M 142_A 0.90 0.00
45_K 218_I 0.90 0.00
96_I 189_A 0.90 0.00
75_Y 29_V 0.90 0.00
17_G 185_I 0.90 0.00
150_D 127_V 0.89 0.00
90_V 61_N 0.89 0.00
129_R 34_K 0.89 0.00
39_L 192_R 0.89 0.00
59_N 315_F 0.88 0.00
156_A 188_I 0.88 0.00
67_I 85_A 0.87 0.00
96_I 257_V 0.87 0.00
126_I 159_W 0.87 0.00
82_K 121_G 0.87 0.00
156_A 214_V 0.87 0.00
152_L 112_T 0.87 0.00
97_K 198_Y 0.87 0.00
93_V 70_A 0.87 0.00
76_E 141_D 0.86 0.00
89_K 42_M 0.86 0.00
124_A 280_L 0.86 0.00
23_E 163_T 0.86 0.00
153_Q 187_I 0.86 0.00
153_Q 84_N 0.86 0.00
121_G 272_C 0.85 0.00
154_E 214_V 0.85 0.00
102_T 213_I 0.85 0.00
124_A 8_V 0.85 0.00
86_K 53_R 0.85 0.00
123_K 129_T 0.84 0.00
33_Q 225_G 0.84 0.00
84_Q 172_G 0.84 0.00
105_G 306_R 0.84 0.00
58_P 30_E 0.84 0.00
97_K 231_L 0.84 0.00
79_K 259_V 0.84 0.00
169_Q 155_H 0.83 0.00
90_V 45_L 0.83 0.00
34_L 165_L 0.83 0.00
38_S 67_V 0.83 0.00
82_K 260_M 0.83 0.00
65_C 297_M 0.83 0.00
172_M 204_P 0.83 0.00
126_I 204_P 0.83 0.00
93_V 106_L 0.83 0.00
66_R 165_L 0.83 0.00
155_L 5_A 0.82 0.00
78_S 145_I 0.82 0.00
113_S 34_K 0.82 0.00
137_H 34_K 0.81 0.00
91_I 214_V 0.80 0.00
25_R 326_F 0.80 0.00
154_E 50_P 0.80 0.00
101_G 236_E 0.80 0.00
79_K 53_R 0.80 0.00
100_P 110_T 0.80 0.00
82_K 280_L 0.80 0.00
152_L 220_F 0.80 0.00
162_P 160_F 0.80 0.00
91_I 270_L 0.79 0.00
119_E 257_V 0.79 0.00
156_A 182_Q 0.79 0.00
149_K 155_H 0.79 0.00
75_Y 213_I 0.79 0.00
79_K 304_M 0.79 0.00
154_E 142_A 0.79 0.00
99_R 108_P 0.79 0.00
127_T 185_I 0.79 0.00
56_I 185_I 0.79 0.00
109_V 231_L 0.79 0.00
82_K 259_V 0.79 0.00
41_E 95_S 0.79 0.00
158_V 73_A 0.79 0.00
140_I 21_V 0.78 0.00
97_K 205_M 0.78 0.00
99_R 142_A 0.78 0.00
154_E 241_I 0.78 0.00
61_E 80_S 0.78 0.00
151_D 272_C 0.78 0.00
73_F 275_V 0.78 0.00
153_Q 52_E 0.78 0.00
96_I 325_Q 0.78 0.00
99_R 201_T 0.78 0.00
48_E 71_L 0.78 0.00
164_K 227_L 0.78 0.00
67_I 128_A 0.77 0.00
26_L 22_A 0.77 0.00
173_V 90_E 0.77 0.00
144_V 116_I 0.77 0.00
144_V 272_C 0.77 0.00
171_I 177_T 0.77 0.00
162_P 216_T 0.77 0.00
49_A 53_R 0.77 0.00
113_S 39_T 0.77 0.00
22_Q 78_L 0.77 0.00
101_G 276_H 0.76 0.00
127_T 125_F 0.76 0.00
36_I 68_Q 0.76 0.00
126_I 183_P 0.76 0.00
112_R 214_V 0.76 0.00
152_L 230_F 0.76 0.00
160_S 314_S 0.76 0.00
101_G 138_H 0.76 0.00
149_K 243_F 0.76 0.00
165_I 119_F 0.76 0.00
164_K 123_L 0.76 0.00
102_T 121_G 0.76 0.00
56_I 234_F 0.75 0.00
169_Q 234_F 0.75 0.00
158_V 116_I 0.75 0.00
108_Q 80_S 0.75 0.00
84_Q 203_T 0.75 0.00
123_K 11_A 0.75 0.00
73_F 35_K 0.75 0.00
160_S 246_S 0.75 0.00
58_P 164_R 0.75 0.00
47_E 221_T 0.75 0.00
77_K 218_I 0.74 0.00
75_Y 25_D 0.74 0.00
113_S 295_F 0.74 0.00
120_E 71_L 0.74 0.00
79_K 313_R 0.74 0.00
90_V 159_W 0.74 0.00
149_K 312_L 0.74 0.00
55_E 242_R 0.74 0.00
134_E 207_H 0.73 0.00
153_Q 288_E 0.73 0.00
108_Q 259_V 0.73 0.00
45_K 41_Q 0.73 0.00
27_T 63_A 0.73 0.00
Legend: The i (protein A) and j (protein B) are positions as given in the UniProt sequences. The value of the raw score is the function of the learning procedure, L2 normalization and APC (entropic) correction.

Scaled Score = raw_score/average(raw_scores)
I_Prob = P(contact | scaled_score, seq/len, top_inter_score)

Text file of predictions
(includes both intra and inter preds)

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