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OPENSEQ.org

CHEA - CHEB
UniProt: P07363 - P07330
Length: 1003
Sequences: 951
Seq/Len: 0.96
I_Prob: 0.01

CHEA - Chemotaxis protein CheA
Paralog alert: 0.28 [within 20: 0.01] - ratio of genomes with paralogs
Cluster includes: CHEA
CHEB - Chemotaxis response regulator protein-glutamate methylesterase
Paralog alert: 0.35 [within 20: 0.03] - ratio of genomes with paralogs
Cluster includes: CHEB
GREMLIN Results (Scaled_score > 1):

Legend: The darker and larger the blue dots, the higher strength in coevolution. Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on HHsearch results which uses the overall probability and per-site alignment confidence. Inter-chain contacts in the pdb are in shades of red.
3kyjA:BContact Map
2r25B:AContact Map
4eukA:BContact Map


Residue pairs sorted by strength in coevolution signal:
i j Scaled Score I_Prob
418_V 105_V 1.41 0.01
503_I 5_R 1.18 0.00
525_I 168_T 1.16 0.00
517_V 308_S 1.15 0.00
327_M 280_L 1.12 0.00
618_P 316_R 1.12 0.00
49_S 82_V 1.08 0.00
527_P 162_G 1.08 0.00
604_Q 168_T 1.06 0.00
513_D 168_T 1.04 0.00
370_I 20_T 1.03 0.00
604_Q 38_P 1.02 0.00
98_M 291_M 1.01 0.00
555_R 68_L 1.01 0.00
514_G 168_T 1.01 0.00
505_L 72_M 0.99 0.00
633_L 199_F 0.99 0.00
344_A 66_D 0.97 0.00
485_M 105_V 0.97 0.00
489_V 95_R 0.96 0.00
430_I 8_S 0.96 0.00
525_I 38_P 0.96 0.00
637_V 33_A 0.96 0.00
327_M 191_M 0.95 0.00
318_Q 104_F 0.94 0.00
49_S 261_D 0.94 0.00
351_V 102_I 0.93 0.00
462_A 79_V 0.93 0.00
378_V 127_V 0.93 0.00
364_K 256_H 0.92 0.00
525_I 301_T 0.92 0.00
8_F 21_E 0.92 0.00
55_G 202_R 0.91 0.00
531_V 276_V 0.91 0.00
378_V 220_V 0.91 0.00
511_I 192_P 0.89 0.00
466_T 8_S 0.89 0.00
264_I 63_D 0.89 0.00
489_V 97_L 0.88 0.00
602_Q 256_H 0.87 0.00
310_L 280_L 0.87 0.00
324_I 318_A 0.87 0.00
390_E 146_T 0.86 0.00
364_K 162_G 0.86 0.00
119_I 191_M 0.86 0.00
319_E 252_A 0.86 0.00
373_P 162_G 0.86 0.00
67_H 290_G 0.86 0.00
208_I 278_V 0.85 0.00
500_T 308_S 0.85 0.00
429_R 269_K 0.85 0.00
513_D 67_F 0.85 0.00
62_L 81_M 0.85 0.00
399_S 257_R 0.84 0.00
341_R 9_V 0.84 0.00
324_I 256_H 0.84 0.00
475_M 171_I 0.84 0.00
119_I 77_M 0.83 0.00
486_G 247_I 0.83 0.00
514_G 301_T 0.83 0.00
64_E 205_K 0.83 0.00
602_Q 202_R 0.83 0.00
473_V 261_D 0.82 0.00
621_S 160_A 0.82 0.00
581_I 168_T 0.82 0.00
337_P 93_T 0.82 0.00
505_L 316_R 0.82 0.00
55_G 163_A 0.82 0.00
377_L 93_T 0.82 0.00
417_E 62_M 0.81 0.00
511_I 230_G 0.81 0.00
623_A 184_A 0.81 0.00
606_V 261_D 0.81 0.00
530_A 279_I 0.81 0.00
480_R 38_P 0.81 0.00
466_T 65_L 0.81 0.00
595_L 171_I 0.81 0.00
512_L 68_L 0.80 0.00
414_I 90_S 0.80 0.00
514_G 38_P 0.80 0.00
475_M 16_R 0.80 0.00
554_V 84_S 0.80 0.00
20_L 229_P 0.80 0.00
476_D 261_D 0.80 0.00
505_L 187_I 0.79 0.00
513_D 38_P 0.79 0.00
476_D 290_G 0.79 0.00
325_R 290_G 0.79 0.00
314_A 305_N 0.79 0.00
398_N 227_I 0.79 0.00
573_A 8_S 0.79 0.00
411_G 172_R 0.79 0.00
486_G 264_F 0.79 0.00
491_I 227_I 0.78 0.00
77_R 58_E 0.78 0.00
9_Y 291_M 0.78 0.00
604_Q 256_H 0.78 0.00
335_R 202_R 0.78 0.00
414_I 93_T 0.78 0.00
542_L 65_L 0.78 0.00
285_Q 58_E 0.78 0.00
533_E 58_E 0.78 0.00
524_F 323_G 0.77 0.00
617_V 334_S 0.77 0.00
287_M 42_R 0.77 0.00
17_D 312_F 0.77 0.00
555_R 230_G 0.77 0.00
466_T 327_V 0.77 0.00
468_V 310_V 0.77 0.00
533_E 86_T 0.77 0.00
141_L 225_A 0.76 0.00
394_A 208_Q 0.76 0.00
63_Q 99_L 0.76 0.00
279_G 78_P 0.76 0.00
500_T 181_S 0.76 0.00
467_D 93_T 0.76 0.00
34_A 307_A 0.76 0.00
285_Q 168_T 0.76 0.00
348_G 79_V 0.76 0.00
549_E 245_I 0.76 0.00
604_Q 67_F 0.75 0.00
198_I 8_S 0.75 0.00
404_I 334_S 0.75 0.00
353_L 57_V 0.75 0.00
439_L 308_S 0.75 0.00
54_A 57_V 0.75 0.00
614_Y 168_T 0.75 0.00
81_M 276_V 0.75 0.00
604_Q 323_G 0.75 0.00
568_F 304_Q 0.75 0.00
322_M 192_P 0.75 0.00
148_E 32_V 0.74 0.00
55_G 68_L 0.74 0.00
630_S 23_I 0.74 0.00
480_R 168_T 0.74 0.00
603_H 280_L 0.74 0.00
477_V 230_G 0.74 0.00
386_I 308_S 0.74 0.00
466_T 304_Q 0.74 0.00
72_L 128_R 0.73 0.00
273_Q 236_L 0.73 0.00
336_Y 93_T 0.73 0.00
270_K 256_H 0.73 0.00
44_F 192_P 0.73 0.00
313_N 71_L 0.73 0.00
634_I 292_L 0.73 0.00
323_S 168_T 0.73 0.00
492_Q 30_E 0.73 0.00
429_R 5_R 0.73 0.00
512_L 74_L 0.72 0.00
555_R 192_P 0.72 0.00
366_L 159_I 0.72 0.00
255_T 220_V 0.72 0.00
508_T 200_A 0.72 0.00
555_R 196_T 0.72 0.00
78_R 98_E 0.72 0.00
483_Q 311_V 0.72 0.00
44_F 10_D 0.72 0.00
38_E 273_R 0.72 0.00
448_D 320_N 0.72 0.00
19_L 291_M 0.72 0.00
465_V 305_N 0.72 0.00
554_V 194_G 0.72 0.00
359_S 88_K 0.72 0.00
622_A 12_S 0.72 0.00
434_A 8_S 0.72 0.00
479_K 191_M 0.72 0.00
329_M 68_L 0.71 0.00
296_D 28_D 0.71 0.00
497_T 331_S 0.71 0.00
367_I 171_I 0.71 0.00
271_V 188_T 0.71 0.00
473_V 290_G 0.71 0.00
386_I 121_E 0.71 0.00
282_V 261_D 0.70 0.00
335_R 213_E 0.70 0.00
468_V 278_V 0.70 0.00
55_G 192_P 0.70 0.00
390_E 228_A 0.70 0.00
285_Q 318_A 0.70 0.00
335_R 192_P 0.70 0.00
601_G 312_F 0.70 0.00
611_E 77_M 0.70 0.00
621_S 25_S 0.70 0.00
621_S 44_L 0.70 0.00
602_Q 280_L 0.70 0.00
457_P 327_V 0.70 0.00
403_L 234_M 0.70 0.00
318_Q 81_M 0.70 0.00
513_D 256_H 0.70 0.00
509_L 281_T 0.70 0.00
114_A 175_L 0.70 0.00
126_L 236_L 0.70 0.00
632_A 281_T 0.70 0.00
372_D 192_P 0.70 0.00
19_L 160_A 0.70 0.00
430_I 63_D 0.69 0.00
511_I 213_E 0.69 0.00
222_T 308_S 0.69 0.00
499_T 105_V 0.69 0.00
555_R 55_L 0.69 0.00
162_I 154_S 0.69 0.00
423_A 5_R 0.69 0.00
Legend: The i (protein A) and j (protein B) are positions as given in the UniProt sequences. The value of the raw score is the function of the learning procedure, L2 normalization and APC (entropic) correction.

Scaled Score = raw_score/average(raw_scores)
I_Prob = P(contact | scaled_score, seq/len, top_inter_score)

Text file of predictions
(includes both intra and inter preds)

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