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Instructions
  • Use the menu to the right to browse the coupling matrix, or select a position from the PSSM below to see what it is coupled with.

Conservation matrix (aka PSSM)
- A F I L V M W Y D E K R H N Q S T G P C
0001 0 -0.9 -0.2 0.2 0.1 -0.5 -1.3 -0.8 0.3 0.7 -0.1 0 -1.3 -0.2 0.3 0.4 -0.1 1.9 0.1 -1
0002 0.4 -0.6 -0.3 0.2 0.3 -0.2 -1.2 -0.6 0.2 0.5 -0.2 0.1 -0.6 -0.2 0.2 0.5 0 0.2 1.1 -0.5
0003 -0.1 0.5 0 0.9 0.6 0.6 -0.5 -0.5 -0.3 0.2 -0.7 -0.2 -0.3 -0.3 -0.2 0.2 0.5 0.1 0 -0.2
0004 0.3 0.2 -0.4 0.5 -0.3 -0.4 -0.5 -0.5 -0.2 -0.4 -0.3 0.1 -0.3 -0.5 -0.1 0.6 0.1 0.4 1.3 -0.2
0005 0.7 0.5 -0.4 0.1 -0.3 -0.8 -1.2 0.6 0.3 0.5 -0.2 0.2 0.2 -0.5 0 0.6 0 -0.3 1.4 -0.8
0006 0.3 -0.1 -0.5 -0.2 -0.5 -0.2 -0.8 -0.5 0.2 0.1 0.1 0.4 0 0.4 0 0.4 -0.1 1 0.1 -0.5
0007 0.5 0.5 -0.3 0.5 0.5 -0.6 1.2 0.4 -0.3 -0.3 -0.5 -0.3 -0.6 -0.3 -0.1 -0.1 -0.3 0.2 -0.1 -0.4
0008 0.1 -0.9 -0.1 0.3 0.1 -0.3 -0.9 -0.5 0.8 1.7 0.6 -0.1 -0.6 -0.4 0.3 0.9 0.7 -0.7 -0.8 -0.5
0009 0.6 -0.9 0.9 0.4 0.6 1.3 -0.9 -0.4 -0.8 0.5 1 0.7 -0.8 -1 0.8 0.1 0.1 -0.9 -0.5 -0.3
0010 0.3 -0.6 0.3 -0.2 0.4 -0.3 -1 -0.3 -0.4 0.3 0.4 0.6 -0.3 -0.4 0.5 0.7 0.1 0.2 -0.6 0.2
0011 -0.3 1 0.9 0.8 1.1 -0.2 -0.6 1.4 -0.8 -0.6 0.2 0.4 -0.1 -0.9 -0.1 0.1 0.6 -1.1 -0.5 -0.4
0012 0.1 -0.5 -0.2 -0.6 0.2 -0.8 -0.7 -0.6 1.8 0.2 0.2 0 -0.3 0.1 -0.2 1.1 1.4 -0.6 -0.2 -0.3
0013 -0.2 -0.6 -0.4 -0.2 -0.3 -0.7 -1.1 -0.7 1 1 -0.4 0.4 0.4 0.2 0.1 1 0.2 0 0.8 -1.1
0014 -0.3 -0.3 -0.9 0.1 -0.5 -0.7 -1.2 -0.5 1.7 0.5 0.5 0.3 -0.1 1.1 0.4 0.9 0.5 0.4 -0.7 -1.1
0015 0.4 -0.2 -0.9 -0.2 -0.1 -0.9 -0.9 -0.7 0.4 -0.3 0.3 0.3 -0.2 1.1 0.2 0.8 -0.7 2.7 -0.6 -0.9
0016 -0.2 -0.2 -0.3 0.8 -0.1 -0.7 -0.2 0.2 -0.4 0.5 0.7 0.7 -0.3 -0.1 0.6 0.1 0.1 -0.5 0 -0.3
0017 -0.3 -0.6 1 1.2 1.8 -0.2 -0.5 -0.3 -1.1 -0.7 0.5 0.6 -0.9 -0.5 -0.4 0.4 0.9 -1.4 1.1 -0.8
0018 0.1 1.1 0.4 0.9 0.3 -0.4 -0.4 0.8 -0.2 0 -0.1 -0.4 0.1 -0.2 -0.3 -0.4 -0.2 -0.1 -0.7 -0.1
0019 0.3 0.7 0.6 0.6 -0.2 -0.1 -0.3 1.1 -0.3 -0.3 0.1 -0.3 0 -0.1 -0.3 -0.2 -0.1 -0.6 -0.3 -0.3
0020 0.5 0.1 1.7 1.3 1.7 -0.3 -0.9 0.4 -0.6 -0.2 -0.1 -0.7 -0.2 -0.9 -0.7 0.3 0.4 -0.6 -0.5 -0.1
0021 0.2 -0.5 0.1 -0.3 -0.4 -0.7 -0.7 -0.3 0.5 0.3 0.4 -0.1 0.7 1 -0.1 0.4 0 -0.1 0.1 -0.7
0022 -0.1 -0.3 0.1 0.3 0 -0.8 -0.8 -0.2 0.4 -0.1 0.2 0.6 0.4 -0.4 -0.1 1 0.8 -0.4 -0.1 -0.5
0023 0.2 -0.3 0.7 0.3 0.8 -0.5 -1.1 -0.7 -0.5 0.7 0.5 0.3 -0.4 0.4 -0.1 0.6 0.1 -0.1 0.3 -0.8
0024 0.8 -0.8 0 0.5 -0.3 -0.8 -1 -0.8 -0.1 0.4 -0.3 0.2 0.3 0.9 0.4 1 1.6 -0.5 -0.2 -0.9
0025 0.3 -0.2 -0.7 0.6 -0.4 -0.4 -0.9 -0.9 -0.6 0.1 1.5 1 0.3 0.3 1 0.3 -0.6 0.7 -0.5 -0.7
0026 0.4 -0.1 1.1 0 0.5 -0.4 -1 -1.1 -0.5 -0.1 0.7 0.8 -0.5 -0.4 0.1 1.4 1.4 -0.9 -0.3 -0.9
0027 0 -0.2 0.4 0.4 0.4 -0.2 -0.4 -0.4 0 -0.6 0.1 0.6 -0.2 0 0.1 0.9 -0.7 0.2 0 -0.3
0028 -0.1 -0.4 -0.2 0 -0.7 -0.3 -0.6 0 -0.5 -0.2 0.1 0.2 0.3 0.1 0.9 1.6 1.4 -0.2 -0.4 -0.8
0029 -0.3 0.7 -0.6 0.6 0 -0.6 1.2 0.8 -0.4 -0.5 -0.2 -0.4 -0.4 0.2 0.4 0.2 -0.6 0.1 0.1 -0.4
0030 0 -0.1 0.7 0.7 0.2 -0.5 -0.8 -0.5 0 0.9 -0.2 -0.3 0.2 0.2 0.4 0.4 0.7 -0.5 -0.6 -0.8
- A F I L V M W Y D E K R H N Q S T G P C
0031 -0.1 -0.4 0.2 0.2 -0.3 -0.5 -0.5 -0.4 0.1 0.1 0.7 0.4 1.1 -0.3 -0.6 0.4 0.2 -0.2 0.2 -0.3
0032 0.4 -0.3 0.3 -0.3 -0.3 -0.6 -0.6 -0.6 -0.6 -0.1 -0.4 0.5 -0.2 -0.6 -0.1 0.8 0.5 -0.6 2.6 -0.1
0033 0.2 -0.8 -0.3 0.7 0 -0.2 -0.9 -0.7 -0.3 -0.3 0.2 0.5 -0.5 -0.5 0.3 0.4 0.1 0.5 0.4 0
Select residue pair below:
i_j Score Prob
0011_0017 2.926 1.00
0010_0020 2.489 1.00
0021_0024 2.472 1.00
0003_0006 2.095 1.00
0009_0017 1.949 1.00
0012_0016 1.621 1.00
0005_0029 1.354 0.99
0014_0017 1.336 0.99
0005_0023 1.300 0.99
0007_0019 1.282 0.99
0021_0026 1.224 0.98
0004_0007 1.221 0.98
0021_0028 1.196 0.98
0008_0022 1.188 0.98
0010_0016 1.072 0.95
0016_0030 1.016 0.93
0002_0031 1.000 0.92
0022_0027 0.962 0.90
0003_0007 0.918 0.87
0001_0030 0.894 0.85
0008_0018 0.882 0.84
0002_0030 0.872 0.83
0011_0016 0.839 0.80
0013_0030 0.825 0.78
0015_0028 0.795 0.75
0023_0026 0.770 0.71
0022_0025 0.759 0.70
0001_0005 0.758 0.70
0005_0011 0.735 0.66
0016_0020 0.714 0.63
0010_0018 0.706 0.62
0019_0031 0.698 0.60
0006_0013 0.661 0.54
0018_0029 0.660 0.54
0013_0029 0.657 0.53
0001_0014 0.624 0.48
0024_0029 0.606 0.45
0015_0019 0.586 0.41
0027_0030 0.583 0.41
0012_0018 0.582 0.41
0009_0030 0.561 0.37
0025_0033 0.554 0.36
0006_0030 0.544 0.35
0027_0032 0.518 0.31
0009_0029 0.506 0.29
0006_0023 0.499 0.28
0005_0030 0.499 0.28
0007_0027 0.493 0.27
Local Interactions:
i_j Score Prob
0031_0033 6.736 1.00
0003_0004 3.859 1.00
0012_0014 3.094 1.00
0008_0010 2.839 1.00
0021_0023 2.445 1.00
0024_0026 1.930 1.00
0023_0024 1.728 1.00
0020_0022 1.693 1.00
0021_0022 1.616 1.00
0025_0027 1.489 1.00
0032_0033 1.477 1.00
0013_0014 1.406 0.99
0004_0006 1.391 0.99
0027_0029 1.369 0.99
0012_0013 1.213 0.98
0014_0016 1.107 0.96
0029_0030 1.089 0.96
0006_0007 1.017 0.93
0031_0032 0.874 0.84
0016_0018 0.843 0.80
0009_0011 0.807 0.76
0011_0013 0.791 0.74
0002_0003 0.655 0.53
0027_0028 0.633 0.49
0018_0019 0.598 0.43
0028_0030 0.590 0.42
0010_0012 0.523 0.31
0019_0021 0.497 0.28
See all coupling residues
Download raw data
Renumber residues to start with:
Position: 1 2 3 4 5 ...
Sequence: V P L P A ...

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