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Instructions
  • Use the menu to the right to browse the coupling matrix, or select a position from the PSSM below to see what it is coupled with.

Conservation matrix (aka PSSM)
- A F I L V M W Y D E K R H N Q S T G P C
0001 0 -0.4 -0.4 -0.4 -0.4 -0.4 0.5 -0.1 -0.4 -0.3 1.1 0.4 0.3 0.8 0.4 0.6 0.2 -0.4 -0.4 -0.4
0002 -0.3 -0.3 0.7 -0.3 -0.3 0 3.1 -0.3 -0.3 -0.3 -0.3 -0.2 -0.3 -0.3 -0.3 0.1 -0.3 -0.3 -0.3 0.1
0003 0 1 0.6 0.8 0.6 0.6 0.3 -0.3 -0.3 -0.3 -0.3 -0.3 -0.3 -0.3 -0.3 -0.3 -0.3 -0.3 -0.3 -0.3
0004 0.1 -0.4 -0.4 -0.2 -0.4 -0.1 0.2 -0.4 -0.4 0.1 1 0.6 -0.2 0.2 0.4 -0.2 0 0.6 -0.4 -0.4
0005 -0.2 -0.2 0.1 -0.2 0.1 -0.2 1 1.7 -0.2 -0.2 -0.2 -0.2 -0.2 -0.2 -0.2 -0.2 -0.2 -0.2 -0.2 0.1
0006 -0.3 -0.3 1.7 1.2 0.8 0.3 -0.3 0 -0.3 -0.3 -0.3 0.1 -0.3 -0.3 -0.3 -0.3 0 -0.3 -0.3 -0.3
0007 -0.3 -0.3 -0.3 0.1 -0.3 0.2 -0.3 0.5 -0.3 -0.3 1.7 0.7 -0.1 -0.1 0.7 -0.3 -0.3 -0.3 -0.1 -0.3
0008 -0.3 -0.2 1.1 1.3 -0.2 0.2 0.6 0.9 -0.3 -0.3 -0.3 -0.3 -0.2 0 -0.3 -0.3 -0.2 -0.3 -0.3 -0.3
0009 1.1 1.2 0.2 -0.3 0.3 -0.4 -0.4 -0.4 -0.4 -0.3 -0.3 -0.3 -0.4 -0.4 -0.4 0 -0.4 2.1 -0.4 -0.3
0010 0.1 0.5 0.7 1.1 1.1 -0.2 -0.4 0.1 -0.4 -0.4 -0.4 -0.2 -0.1 -0.1 -0.4 -0.4 -0.4 0.1 -0.4 -0.4
0011 -0.4 0.5 0.8 1.2 -0.4 0.7 -0.4 1.1 -0.4 -0.4 -0.2 -0.4 -0.3 0.2 -0.4 -0.4 -0.4 -0.4 -0.4 0.1
0012 0.6 -0.3 1.1 0.8 1.2 0 -0.3 -0.3 0.3 -0.3 -0.1 -0.3 -0.3 -0.1 -0.3 -0.3 -0.2 -0.3 -0.3 -0.3
0013 -0.1 -0.2 1.4 0.1 1 -0.2 0.1 -0.2 -0.2 -0.2 -0.2 -0.2 -0.2 -0.2 -0.2 0.4 -0.2 0.5 -0.2 -0.2
0014 1.1 -0.4 0.9 0.7 0.9 -0.2 -0.4 -0.4 -0.4 -0.3 -0.4 0.8 -0.4 -0.4 -0.4 -0.4 -0.4 0.8 -0.4 -0.4
0015 0.9 -0.3 0.3 -0.1 0.4 -0.3 -0.3 -0.3 -0.3 -0.3 -0.3 0.5 -0.3 -0.3 -0.3 0.4 -0.3 1.5 -0.3 -0.3
0016 -0.4 -0.1 2.1 2.2 1.6 -0.3 -0.4 -0.1 -0.4 -0.4 -0.4 -0.4 -0.4 -0.4 -0.4 -0.4 -0.4 -0.4 -0.4 -0.4
0017 -0.3 -0.3 1.4 0.5 1.5 -0.3 -0.3 -0.3 0.3 -0.3 -0.3 -0.1 -0.3 0 -0.3 -0.3 -0.3 0 0 -0.3
0018 0.8 -0.3 0.2 0.8 0.8 -0.1 -0.3 -0.3 -0.3 -0.3 -0.3 0.5 -0.3 -0.3 -0.3 0 -0.3 1.4 -0.3 -0.3
0019 0.4 1.3 0.5 1 0.4 -0.3 -0.2 -0.3 -0.3 -0.3 -0.3 0 -0.3 -0.3 -0.3 -0.3 -0.3 0 -0.3 0
0020 -0.2 -0.2 0.1 -0.2 -0.2 -0.2 -0.2 -0.2 -0.2 0.1 1.1 2.4 -0.2 0 -0.2 -0.2 -0.2 -0.2 -0.2 -0.2
0021 -0.1 0.1 1.7 0.3 1 0.4 -0.3 -0.3 -0.3 -0.3 0 -0.3 -0.3 0.2 -0.3 -0.3 -0.3 -0.3 -0.3 -0.3
0022 0.6 0.2 0.7 1.1 1.2 -0.2 -0.4 -0.4 -0.4 -0.4 -0.4 -0.4 -0.4 0.5 -0.4 0 -0.3 -0.1 -0.4 0
0023 0.4 0.9 0.3 0.4 0.2 0.7 0.5 -0.1 -0.4 -0.4 -0.4 -0.4 -0.4 -0.4 -0.4 0.3 -0.4 0.2 -0.4 -0.1
0024 1.1 0.7 0.3 0.4 0.8 -0.2 -0.1 1 -0.6 -0.6 -0.6 -0.6 -0.6 -0.6 -0.6 0.1 0.6 -0.2 -0.6 0.6
0025 -0.3 -0.3 1.9 1.1 1.6 -0.3 -0.3 -0.3 -0.3 0.2 -0.3 -0.3 -0.3 -0.3 -0.3 0.1 -0.3 -0.2 -0.3 0.1
0026 0.3 0.5 0.3 0.6 0.7 0.2 0.3 0 -0.3 -0.3 -0.3 0 -0.3 -0.3 -0.3 -0.3 -0.2 -0.1 -0.3 -0.3
0027 0 0 -0.5 -0.1 -0.5 -0.5 -0.5 -0.5 -0.5 -0.5 -0.5 -0.2 -0.4 1.1 1.4 1.9 0.4 1.2 -0.5 -0.5
0028 -0.5 -0.5 1.2 1 1.1 0.7 -0.5 -0.1 -0.5 -0.5 -0.2 -0.5 -0.5 -0.2 -0.1 0.3 0.4 -0.3 -0.5 0.9
0029 -0.2 0.2 1.4 1.3 1 -0.3 -0.3 -0.3 -0.3 -0.3 -0.3 -0.3 -0.3 -0.3 -0.2 0.2 -0.3 0 -0.3 -0.3
0030 0.9 -0.6 -0.5 -0.5 0.1 -0.6 -0.6 -0.1 -0.2 -0.4 0.5 1.4 -0.2 1.4 -0.6 1.4 -0.6 0.8 -0.6 -0.6
- A F I L V M W Y D E K R H N Q S T G P C
0031 -0.4 -0.4 0.1 0.3 -0.4 -0.2 -0.4 -0.4 -0.4 -0.4 1.4 1.3 -0.4 0.3 -0.2 0.2 0.1 0.1 -0.4 -0.4
0032 0.4 0.7 0.7 1.1 0.4 0.5 -0.4 -0.4 -0.4 -0.4 -0.4 -0.4 -0.4 -0.4 -0.4 -0.1 -0.2 0.4 -0.4 -0.4
0033 -0.3 -0.4 -0.4 -0.1 -0.1 0.3 -0.4 -0.4 -0.4 0 -0.1 2.2 -0.4 -0.4 -0.4 0 -0.2 0.3 -0.4 0.7
0034 0.7 -0.4 -0.1 0.5 -0.3 -0.4 -0.4 -0.4 -0.4 0 0.8 1.1 -0.4 -0.3 1 -0.4 -0.4 -0.4 -0.4 -0.4
0035 -0.1 -0.3 -0.3 0.1 0 -0.3 -0.3 -0.3 0.1 -0.3 0.1 0.4 -0.3 -0.3 -0.3 -0.1 -0.3 2 -0.3 -0.3
0036 -0.2 0.7 0.4 -0.2 -0.1 -0.2 -0.2 0.5 -0.2 -0.2 0.1 0.1 -0.2 -0.2 0.1 -0.2 0.1 -0.2 -0.2 -0.1
0037 0.3 -0.1 -0.3 0.4 0 -0.2 -0.3 -0.1 -0.3 -0.3 -0.1 0.4 0.1 -0.1 0.2 0.7 0.2 -0.1 -0.3 -0.3
0038 -0.1 -0.3 0 0.1 0.2 -0.3 -0.3 -0.3 -0.3 -0.3 0.1 0.2 0.3 -0.3 0 0.3 0.2 -0.3 0.5 -0.3
0039 -0.3 -0.1 0.7 1.9 0.9 -0.2 -0.3 0 -0.3 -0.3 -0.3 -0.3 -0.3 -0.3 -0.3 -0.3 -0.3 -0.3 -0.2 -0.3
0040 -0.1 0.6 -0.1 0.2 0.2 -0.4 -0.4 -0.4 -0.4 -0.4 -0.4 -0.1 -0.4 -0.4 0.1 1.3 -0.4 0.3 0.5 -0.1
Select residue pair below:
i_j Score Prob
0014_0018 2.422 1.00
0006_0012 1.673 1.00
0004_0007 1.628 1.00
0011_0018 1.551 1.00
0013_0019 1.526 1.00
0013_0017 1.487 1.00
0021_0029 1.483 1.00
0016_0026 1.459 1.00
0003_0010 1.417 1.00
0037_0040 1.393 0.99
0013_0030 1.360 0.99
0031_0035 1.309 0.99
0011_0015 1.189 0.98
0032_0038 1.141 0.97
0015_0023 1.129 0.97
0033_0038 1.099 0.96
0013_0018 1.085 0.96
0032_0037 1.073 0.95
0011_0014 1.062 0.95
0023_0030 1.055 0.95
0007_0010 1.049 0.94
0001_0026 1.040 0.94
0020_0026 1.033 0.94
0035_0038 1.024 0.93
0036_0039 0.975 0.91
0003_0009 0.974 0.91
0021_0027 0.931 0.88
0032_0035 0.925 0.88
0024_0028 0.898 0.86
0012_0022 0.885 0.85
0006_0019 0.860 0.82
0007_0025 0.844 0.81
0005_0037 0.841 0.80
0002_0020 0.837 0.80
0023_0029 0.831 0.79
0001_0014 0.820 0.78
0012_0018 0.800 0.75
0031_0036 0.798 0.75
0007_0016 0.797 0.75
0008_0025 0.775 0.72
0004_0014 0.771 0.71
0018_0022 0.768 0.71
0005_0008 0.759 0.70
0033_0036 0.754 0.69
0021_0026 0.731 0.66
0014_0017 0.718 0.64
0003_0008 0.708 0.62
0031_0034 0.704 0.61
0024_0029 0.693 0.59
0032_0040 0.682 0.58
0001_0005 0.670 0.56
0025_0028 0.668 0.55
0003_0016 0.667 0.55
0009_0037 0.650 0.52
0023_0026 0.649 0.52
0001_0029 0.646 0.52
0017_0026 0.643 0.51
0001_0015 0.643 0.51
Local Interactions:
i_j Score Prob
0039_0040 2.979 1.00
0035_0036 2.269 1.00
0036_0038 2.197 1.00
0010_0012 2.185 1.00
0004_0006 2.036 1.00
0003_0005 1.906 1.00
0038_0039 1.903 1.00
0008_0010 1.886 1.00
0031_0032 1.858 1.00
0005_0006 1.789 1.00
0007_0008 1.726 1.00
0033_0034 1.516 1.00
0036_0037 1.480 1.00
0009_0011 1.362 0.99
0025_0026 1.314 0.99
0034_0036 1.137 0.97
0038_0040 1.131 0.97
0015_0017 1.128 0.97
0017_0019 1.085 0.96
0021_0022 1.039 0.94
0010_0011 1.021 0.93
0034_0035 1.000 0.92
0023_0024 0.974 0.91
0037_0039 0.962 0.90
0009_0010 0.938 0.89
0012_0014 0.936 0.89
0019_0021 0.930 0.88
0018_0019 0.858 0.82
0023_0025 0.843 0.80
0003_0004 0.821 0.78
0020_0022 0.802 0.76
0027_0029 0.766 0.71
0013_0015 0.762 0.70
0012_0013 0.749 0.68
0028_0029 0.732 0.66
0004_0005 0.717 0.63
0026_0028 0.694 0.60
0022_0023 0.670 0.56
See all coupling residues
Download raw data
Renumber residues to start with:
Position: 1 2 3 4 5 ...
Sequence: N W L W Y ...

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