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Instructions
  • Use the menu to the right to browse the coupling matrix, or select a position from the PSSM below to see what it is coupled with.
Conservation matrix (aka PSSM)
- A F I L V M W Y D E K R H N Q S T G P C
0001 0.2 -0.2 -0.2 0.1 0.1 0.2 -0.2 -0.2 -0.2 0.1 0.8 -0.2 -0.2 -0.2 -0.2 0.1 -0.2 -0.2 0.4 -0.2
0002 0.4 -0.3 -0.3 -0.3 -0.3 0.3 -0.3 -0.3 -0.3 0.3 1 0.3 -0.3 -0.3 0.5 -0.3 0.3 -0.3 -0.3 -0.3
0003 0.2 0.2 -0.1 -0.1 -0.1 -0.1 -0.1 -0.1 -0.1 0.2 -0.1 0.2 -0.1 -0.1 -0.1 -0.1 -0.1 0.9 -0.1 -0.1
0004 0.1 -0.2 0.1 0.1 0.3 -0.2 -0.2 -0.2 -0.2 0.5 0.3 0 -0.2 0.1 0.1 -0.2 -0.2 0.2 -0.2 -0.2
0005 0.3 -0.2 0.8 0.5 1.2 -0.2 -0.2 -0.2 -0.2 -0.2 -0.2 -0.2 -0.2 -0.2 -0.2 0.3 -0.2 -0.2 -0.2 -0.2
0006 -0.2 0.6 -0.2 0.1 0.2 -0.2 -0.2 0.2 -0.2 -0.2 -0.2 -0.2 -0.2 -0.2 -0.2 -0.2 -0.2 0.1 -0.2 1.2
0007 -0.1 -0.1 -0.1 -0.1 -0.1 -0.1 -0.1 -0.1 0.9 -0.1 -0.1 -0.1 -0.1 0.6 -0.1 -0.1 -0.1 -0.1 0.2 -0.1
0008 0.1 -0.2 0.5 -0.2 1.3 -0.1 -0.2 -0.2 -0.2 0.1 -0.2 -0.2 -0.2 -0.2 0 -0.2 -0.2 0 -0.2 -0.2
0009 -0.2 -0.2 -0.2 -0.2 -0.2 -0.2 -0.2 0.1 0.5 0.4 0 -0.2 -0.2 0.6 -0.2 0.1 -0.2 -0.2 -0.2 0.1
0010 -0.1 -0.1 -0.1 -0.1 -0.1 -0.1 -0.1 -0.1 -0.1 -0.1 -0.1 0.2 -0.1 -0.1 -0.1 -0.1 -0.1 0.5 -0.1 -0.1
0011 -0.3 0 -0.1 -0.3 0.6 0 -0.3 -0.3 -0.3 -0.1 0.4 0.2 -0.3 1 -0.3 -0.3 0.3 -0.3 -0.3 -0.3
0012 -0.2 -0.2 -0.2 -0.2 -0.2 -0.2 -0.2 0.1 -0.2 0.1 -0.2 -0.2 -0.2 -0.2 -0.2 0.9 -0.2 -0.2 -0.2 1.7
0013 -0.2 -0.2 0.3 -0.2 1.2 -0.2 -0.2 -0.2 0.2 -0.2 -0.2 -0.2 -0.2 -0.2 -0.2 -0.2 -0.2 -0.2 -0.2 -0.2
0014 -0.1 -0.1 -0.1 -0.1 -0.1 -0.1 -0.1 0 1.1 -0.1 -0.1 -0.1 -0.1 -0.1 -0.1 -0.1 0.2 -0.1 -0.1 -0.1
0015 1.8 -0.2 -0.2 0.1 0.7 -0.2 -0.2 -0.2 0.1 -0.2 -0.2 -0.2 -0.2 -0.2 -0.2 0.1 -0.2 -0.2 -0.2 -0.2
0016 0.2 -0.2 -0.2 0.2 0.2 0.3 -0.2 -0.2 0.7 -0.2 0.2 -0.2 -0.2 -0.2 0.2 0.1 0.1 0 0.1 -0.2
0017 -0.3 -0.3 -0.3 -0.3 -0.3 -0.3 -0.3 -0.3 0.9 1.7 0.3 -0.3 -0.3 1 0 -0.3 0 0.3 -0.3 -0.3
0018 -0.1 -0.1 -0.1 -0.1 -0.1 -0.1 -0.1 -0.1 2.2 -0.1 0.3 -0.1 -0.1 -0.1 -0.1 -0.1 -0.1 -0.1 -0.1 -0.1
0019 -0.1 -0.1 0.2 -0.1 -0.1 -0.1 -0.1 -0.1 0.4 1.7 -0.1 -0.1 -0.1 0.2 -0.1 -0.1 -0.1 -0.1 -0.1 -0.1
0020 -0.2 0.9 0.7 0.6 0.3 0.6 -0.2 -0.2 -0.2 -0.2 -0.2 -0.2 0.1 -0.2 -0.2 -0.2 -0.2 -0.2 -0.2 -0.2
0021 -0.2 3.8 -0.2 -0.2 -0.2 -0.2 -0.2 0.2 -0.2 -0.2 -0.2 -0.2 -0.2 -0.2 -0.2 -0.2 -0.2 -0.2 -0.2 -0.2
0022 -0.2 -0.2 -0.2 -0.2 -0.2 0.1 -0.2 -0.2 -0.2 0.5 1.3 1.7 -0.2 -0.2 -0.2 -0.1 0.2 -0.2 -0.2 -0.2
0023 -0.2 -0.2 0.2 2.4 -0.2 0.3 -0.2 -0.2 -0.2 -0.2 -0.2 -0.2 -0.2 -0.2 -0.2 -0.2 -0.2 -0.2 -0.2 -0.2
0024 -0.1 -0.1 0.3 -0.1 -0.1 -0.1 -0.1 -0.1 -0.1 -0.1 -0.1 0.2 -0.1 -0.1 -0.1 0.3 0.8 -0.1 -0.1 -0.1
0025 -0.2 -0.2 -0.2 -0.2 -0.2 -0.2 -0.2 -0.2 -0.2 -0.2 -0.2 0.2 0.2 -0.2 -0.2 1.2 1.8 -0.2 -0.2 -0.2
0026 -0.2 -0.2 -0.2 -0.2 -0.2 -0.2 -0.2 -0.2 0.2 0.3 0.9 0.7 -0.2 0.2 -0.2 0.1 -0.2 -0.2 -0.2 -0.2
0027 -0.2 -0.2 -0.2 -0.2 -0.2 -0.2 -0.2 -0.2 0.8 0.8 0.1 0.1 -0.2 0.1 0.1 -0.2 -0.2 0.8 -0.2 -0.2
0028 -0.1 -0.1 -0.1 -0.1 -0.1 -0.1 -0.1 -0.1 -0.1 -0.1 -0.1 0.1 -0.1 0.3 -0.1 -0.1 -0.1 1.8 -0.1 -0.1
0029 -0.2 -0.2 -0.2 -0.2 -0.2 -0.2 -0.2 -0.2 -0.2 0.1 2.2 0.1 0.5 -0.2 0.4 -0.2 0.1 -0.2 -0.2 -0.2
0030 -0.1 1.2 -0.1 1.2 -0.1 0.2 -0.1 -0.1 -0.1 -0.1 -0.1 -0.1 -0.1 -0.1 -0.1 -0.1 -0.1 -0.1 -0.1 -0.1
- A F I L V M W Y D E K R H N Q S T G P C
0031 1.1 -0.2 0.3 -0.2 0.1 -0.1 -0.2 -0.2 0.4 -0.2 0.1 -0.2 -0.2 -0.2 -0.2 0.7 0.4 -0.2 -0.2 -0.2
0032 -0.2 -0.2 -0.2 0.5 3.5 -0.2 -0.2 -0.2 -0.2 -0.2 0.1 -0.2 -0.2 -0.2 -0.2 0.1 -0.2 -0.2 -0.2 -0.2
0033 -0.2 -0.2 -0.2 -0.2 0.5 -0.2 -0.2 -0.2 -0.2 0.9 0.5 -0.2 -0.2 0.2 0.2 -0.2 -0.2 -0.2 0.2 -0.2
0034 0.2 -0.2 -0.2 -0.2 -0.2 -0.1 0.1 -0.2 -0.2 -0.2 -0.2 1 -0.1 -0.2 -0.2 -0.2 0.5 0.6 -0.2 -0.2
0035 -0.3 0.1 -0.3 -0.1 -0.3 -0.3 -0.3 -0.3 1.7 1.5 0 -0.1 -0.1 -0.3 -0.3 0 0 0.4 -0.3 -0.3
0036 0 -0.3 -0.3 0 0.7 -0.3 -0.3 -0.3 -0.3 -0.1 0.9 0.2 -0.1 -0.3 0.2 0.9 0.3 -0.1 -0.1 -0.3
0037 -0.2 0.3 0.3 0.5 1.8 -0.2 -0.3 -0.3 -0.3 -0.3 0.2 -0.3 0 -0.3 -0.3 0.2 0.2 -0.1 0 -0.3
0038 0.2 -0.3 0 -0.3 -0.3 -0.3 -0.3 0 -0.1 0.4 1 0.7 -0.3 0 -0.1 0.2 0.4 0 -0.3 -0.3
0039 -0.3 -0.3 0.4 0 0.4 0 -0.3 -0.3 -0.3 -0.3 0.2 0 -0.3 0 -0.3 -0.3 0.7 0 0 -0.3
0040 0.3 0 -0.3 -0.3 0.1 0 -0.3 -0.3 0 0.4 1 -0.3 -0.3 0 -0.2 0.2 -0.3 -0.3 -0.2 -0.3
0041 0 -0.3 -0.3 -0.3 -0.3 0.3 -0.3 -0.3 0 1.1 0.7 0.2 -0.3 0.2 -0.3 -0.3 0.4 -0.3 0.1 -0.3
0042 0 -0.3 -0.2 -0.2 0.3 -0.1 -0.3 -0.3 -0.3 0.1 0.4 0.3 -0.3 -0.1 0.3 0 0.2 0.5 0.1 -0.3
0043 0 -0.3 -0.3 -0.3 -0.3 0.2 -0.3 -0.3 0.4 1 0 -0.3 0 0.2 -0.1 -0.2 -0.3 0.6 0.3 -0.3
0044 0.1 0.7 0.7 0.7 0.1 0.3 -0.2 -0.2 -0.2 -0.2 -0.2 -0.2 -0.2 -0.2 -0.2 -0.2 -0.2 -0.2 -0.2 -0.1
0045 -0.1 -0.1 -0.2 0.3 0 -0.2 -0.2 -0.2 0.5 0.2 -0.2 0.1 -0.2 -0.2 0.1 1 -0.2 -0.1 -0.2 -0.2
0046 0.4 -0.2 -0.2 -0.2 -0.2 0.1 -0.2 -0.2 -0.2 -0.2 0.1 -0.2 -0.2 -0.2 -0.2 0 -0.2 0.5 0.7 -0.2
Select residue pair below:
i_j Score Prob
0007_0030 1.748 0.93
0025_0031 1.653 0.90
0001_0033 1.582 0.88
0011_0031 1.574 0.87
0012_0016 1.523 0.85
0026_0046 1.489 0.83
0020_0045 1.476 0.82
0022_0029 1.431 0.79
0042_0045 1.416 0.78
0009_0030 1.375 0.76
0006_0040 1.323 0.72
0005_0009 1.236 0.64
0004_0008 1.207 0.61
0019_0034 1.204 0.61
0015_0033 1.195 0.60
0006_0016 1.170 0.58
0001_0041 1.156 0.56
0006_0020 1.117 0.52
0041_0045 1.069 0.48
0004_0044 1.064 0.47
0008_0044 1.060 0.47
0019_0024 1.055 0.46
0008_0043 1.054 0.46
0020_0046 1.051 0.46
0027_0046 1.033 0.44
0040_0044 1.030 0.44
0002_0046 1.013 0.42
0006_0039 0.975 0.38
0002_0043 0.968 0.38
0005_0011 0.968 0.38
0003_0010 0.933 0.35
0001_0035 0.933 0.35
0038_0043 0.925 0.34
0027_0033 0.913 0.33
0036_0039 0.901 0.32
0013_0033 0.896 0.31
0004_0028 0.888 0.31
0003_0034 0.886 0.30
0014_0024 0.881 0.30
0026_0030 0.878 0.30
0016_0035 0.875 0.29
0016_0042 0.873 0.29
0027_0030 0.869 0.29
0020_0036 0.830 0.26
0017_0045 0.827 0.26
0008_0037 0.824 0.25
0039_0042 0.822 0.25
0002_0009 0.817 0.25
0020_0027 0.790 0.23
0009_0045 0.789 0.23
0038_0041 0.781 0.22
0018_0028 0.774 0.22
0011_0042 0.773 0.22
0014_0023 0.771 0.22
0007_0010 0.764 0.21
0036_0041 0.761 0.21
0005_0044 0.754 0.20
0010_0013 0.753 0.20
0034_0046 0.747 0.20
0001_0015 0.746 0.20
0010_0024 0.742 0.20
0001_0016 0.739 0.20
0008_0011 0.735 0.19
0026_0031 0.727 0.19
0013_0026 0.725 0.19
0001_0006 0.716 0.18
0031_0044 0.716 0.18
0003_0007 0.711 0.18
Local Interactions:
i_j Score Prob
0005_0006 1.216 0.62
0003_0004 1.051 0.46
0010_0012 0.943 0.35
0042_0043 0.853 0.28
0037_0038 0.852 0.28
0040_0041 0.841 0.27
0016_0017 0.808 0.24
0038_0039 0.800 0.24
0040_0042 0.738 0.19
0007_0009 0.730 0.19
0024_0025 0.715 0.18
See all coupling residues
Download raw data
Renumber residues to start with:
Position: 1 2 3 4 5 ...
Sequence: P K G E I ...
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