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CDR1 Return to Main Page
Instructions
  • Use the menu to the right to browse the coupling matrix, or select a position from the PSSM below to see what it is coupled with.
Conservation matrix (aka PSSM)
- A F I L V M W Y D E K R H N Q S T G P C
0001 0.2 1 1.9 2.3 1.2 1.7 -0.8 -0.5 -0.8 -0.6 -0.8 -0.8 -0.8 -0.8 -0.5 0 0 -0.8 -0.5 -0.8
0002 1.1 -0.8 0.6 0.7 0.8 -0.1 -0.8 -0.8 -0.5 0.6 -0.8 -0.6 -0.8 -0.2 -0.2 1.1 1.6 0.6 -0.8 -0.5
0003 0.5 0.1 0.1 0 0.3 -0.2 -0.5 -0.5 -0.1 -0.5 -0.4 -0.5 -0.5 1.5 -0.5 1.3 0.8 0.1 -0.5 -0.5
0004 -0.4 -0.4 -0.4 0 -0.4 -0.4 -0.4 -0.4 0.2 3.4 -0.4 0 -0.4 -0.2 1.8 -0.4 -0.4 -0.4 -0.4 -0.4
0005 0 0.8 0.7 1.1 0.5 0.9 -0.4 0.6 -0.4 -0.4 -0.4 -0.4 -0.4 -0.4 -0.4 -0.4 0.1 -0.4 -0.4 -0.4
0006 0.1 -0.1 -0.8 -1 -0.3 0 -0.9 0.1 -0.1 -0.2 1 1.6 1.3 0.2 0 0.8 0.1 0.9 -1.2 -1.2
0007 0.2 -0.7 -0.9 -0.6 -0.9 -0.9 -0.9 -0.3 1.5 -0.4 -0.1 1.2 0.6 1.5 -0.9 0.7 0.7 2.4 -0.7 -0.9
0008 -0.3 -0.9 1.3 2 0.8 0.4 -1.1 -0.8 -0.5 -1 0.6 2.1 -0.5 -0.6 0.9 0 0.8 -0.6 -0.8 -1
0009 -0.7 -1.2 0.8 0 0.5 -0.9 -0.7 -0.8 1.5 1.3 0.5 0.3 0.2 1.1 0.7 1 0.8 -1.2 -1 -1.4
0010 0.5 0.8 1.3 1.5 0.1 1.4 0 0.7 -0.6 -0.6 -0.6 -0.6 -0.6 -0.6 -0.6 -0.4 -0.6 -0.2 -0.4 -0.6
0011 0.8 -1.2 -0.5 0.3 -0.3 -1.1 -1.2 -0.9 1.1 1.4 0.5 0.5 -0.5 -0.1 0.7 0.6 1.1 -0.4 1.6 -1.4
0012 -0.3 -0.3 -0.3 -0.3 -0.3 -0.3 -0.3 -0.3 -0.3 0.1 -0.3 0.1 -0.3 -0.3 -0.3 -0.3 -0.3 -0.3 -0.3 4.5
0013 2 -1.3 -0.1 -0.3 1.6 -1.1 -1.5 -0.8 1.5 0.9 -0.3 -1.5 -0.9 0.8 -0.5 2.7 1.8 0.3 -0.7 -1.5
0014 0.9 -0.8 -1.4 -0.2 -0.2 -0.2 -1.5 0.2 0.1 0.4 -0.3 -0.3 -1 0.4 1.1 1.7 0.8 1 -0.6 -1.4
0015 0.4 1.5 2 1.2 1.2 0.5 -0.6 1.6 -0.8 -0.7 -1 -0.8 -1 -0.6 -1 0.3 0.2 -0.7 -0.5 -1
0016 0.8 0.2 2.2 0.9 2.6 -0.1 -0.8 -0.8 -0.7 -0.8 -0.8 -0.8 -0.8 -0.8 -0.1 0.2 0.5 -0.1 -0.8 -0.8
0017 -0.5 -0.2 -0.2 1 -0.2 -0.5 -0.5 0.1 -0.2 -0.5 -0.2 -0.5 -0.5 -0.5 -0.5 -0.3 -0.2 -0.5 4.4 -0.5
0018 0.7 0.5 -1 -0.7 -0.2 -0.6 -1.3 0.2 0.6 -0.3 -1.1 0.9 -0.3 0.6 0.8 1.1 0.6 0.4 0.6 -1.2
0019 0.5 -0.1 0.1 -0.2 0.6 -0.4 -0.7 0.7 -0.2 -0.7 -0.7 -0.7 -0.7 0.4 -0.1 -0.1 -0.2 1.6 0.4 -0.7
0020 1.1 -0.5 -0.5 0.1 -0.1 -0.8 -1 -0.7 0.2 0.3 -0.4 -0.5 -1 -0.6 -0.1 1.2 -0.1 1.7 2.5 -1
0021 0.7 -0.1 -0.5 0.1 0 -0.7 -0.9 -0.5 0.4 0.3 -1 -0.4 -0.9 0.5 0.1 0.8 0.4 1.6 0.8 -1
0022 0.4 0.3 0.4 0.7 0.6 -0.5 -0.6 1.7 -0.2 -0.8 -0.8 -0.2 -0.1 0 -0.6 0 -0.8 -0.1 0.7 -0.8
0023 1.1 -1 -0.6 -0.1 0.2 -0.6 -1 -0.2 0.3 -0.9 -0.3 -0.1 -0.8 0.5 0.1 0.7 0.6 0.5 1 -1
0024 0.2 -0.8 -0.6 -0.2 -0.2 -0.5 -0.8 0 1.2 0.4 -0.3 -0.4 -0.4 1.3 0.3 0.6 0.5 1.1 -0.6 -0.8
0025 0.5 -0.4 0.7 1.1 1.1 -0.4 0 -0.1 -0.1 -0.3 -0.9 -0.5 -0.9 -0.3 -0.3 0.4 0.5 0.5 0 -0.9
0026 0.6 -0.8 -0.4 -0.1 -0.2 -0.6 -0.9 -0.9 0.6 0.2 -0.3 -0.4 -0.8 0.5 -0.4 1.2 0.9 1 0.6 -0.9
0027 0.9 -0.4 -0.1 0.6 0.2 -0.4 -1.3 -1.3 0.3 -0.7 -1.3 -0.4 -0.9 0 -0.2 1.5 0.3 1 1.4 -1.5
0028 0.8 -0.7 -0.9 0.4 -0.2 -0.7 -1.4 -1 1.1 0.8 -0.4 -0.1 -0.8 0.7 0.7 1.5 0.7 0.4 0.1 -1.4
0029 0.6 0.3 -1.1 -0.1 -0.7 -0.7 -1.1 0.7 0.1 0.6 -0.9 -0.6 0.7 1.5 0.5 1.6 0.5 0 -0.9 -1.1
0030 -0.2 0.5 -0.3 -0.5 0.6 0 -0.1 -0.5 -0.9 -0.7 1.7 2.1 0.2 -0.5 1.5 -0.1 0.1 -0.5 -0.9 -0.8
- A F I L V M W Y D E K R H N Q S T G P C
0031 2 -0.6 2 -0.5 2.2 -0.4 -0.8 -0.8 -0.8 -0.7 -0.8 -0.8 -0.8 -0.8 -0.3 1.4 1.6 1.3 -0.6 -0.8
0032 -0.2 0.2 -0.2 -0.2 -0.2 -0.2 -0.2 0.5 -0.2 -0.2 -0.2 -0.2 -0.2 -0.2 -0.2 -0.2 0.2 -0.2 -0.2 1.8
0033 1.6 -0.5 -0.1 0.1 0.5 -0.2 -0.7 -0.4 0.1 -0.5 -0.7 -0.4 -0.7 0 -0.3 0.6 1.5 0.2 1.5 -0.7
0034 0.8 0.5 1 -0.5 1.1 0.3 -0.3 0.2 -0.4 0.2 -0.7 -0.6 -0.7 -0.5 -0.2 0.4 0.7 0.2 -0.5 -0.3
0035 1.2 -0.5 0.5 0.1 1.3 -0.8 -1.1 -0.2 -1.1 -0.4 0.2 -0.2 -1 -0.2 0.8 0.7 0.8 -0.3 1 -1.1
0036 1.4 -0.5 -0.5 -0.5 -0.5 -0.5 -0.5 -0.2 -0.5 -0.2 -0.2 0.6 -0.5 -0.4 -0.5 1.6 0.2 3.2 -0.4 -0.5
0037 3.2 -0.2 -0.5 -0.5 -0.6 -0.3 -0.7 0 -0.5 -0.6 -0.7 0 -0.7 0.3 -0.4 2.2 0.3 1.6 -0.7 -0.7
0038 0.5 -1 0.4 -0.1 0.2 -0.5 -0.9 -1 1 1 -0.2 -0.1 -0.6 0.6 0.5 1 0.8 -0.5 0.6 -1.1
0039 2 -0.9 -0.2 0.8 1 -0.9 -1.4 -1.2 -0.9 -0.2 0 0.2 -1 -0.8 0.6 0.9 0.7 0.3 2.9 -1.4
0040 0.6 -0.4 -0.6 -0.6 0 -0.6 -0.6 -0.6 0.8 -0.1 -0.6 0.2 -0.6 1.2 -0.4 0.9 -0.2 2.6 -0.6 -0.6
0041 1.1 -0.4 -0.6 0.1 -0.5 -1 -1.4 -0.8 0.6 1.5 -0.1 0.1 -0.5 0.6 2 2 0.8 -0.2 -1.4 -0.9
0042 0.2 -0.4 -0.1 0.7 -0.5 -0.1 -0.9 -0.3 0.2 -0.2 -0.5 0.6 -0.1 0.7 0.2 0.9 0.8 0.2 0.6 -1.2
0043 0.1 1.1 0.6 0.3 0.7 0.1 -0.6 1.3 -0.1 0.1 -0.1 -0.3 -0.8 0 0 1.1 1.1 -0.9 -1.4 -1.4
0044 -0.3 0.9 2.3 1.4 3.1 -0.6 -0.6 -0.3 -0.6 -0.6 -0.6 -0.6 -0.6 -0.6 -0.6 -0.6 0.6 -0.6 -0.6 -0.6
0045 0.1 -0.6 -0.1 -0.2 -0.5 -0.9 -1.1 -0.4 1.6 0.5 -0.1 0.1 -0.5 0.6 0.5 1.8 1 -0.6 1 -1.1
0046 0.4 -0.4 -0.4 -0.4 -0.4 -0.4 -0.4 -0.4 -0.4 -0.4 -0.4 -0.1 -0.4 -0.4 -0.4 0.3 -0.4 4.9 0.7 -0.4
0047 1.4 -1.2 -0.1 -0.1 -0.5 -0.3 -1.2 -0.8 0.9 1.3 0.2 0.6 -0.7 0.5 -0.1 1.9 1 -0.1 -0.5 -1.2
0048 1.3 -0.2 0 -0.1 0.2 -0.9 -1.3 -0.9 2.7 1.1 -0.2 0.4 -0.8 0.9 0.7 1.1 0.9 -1 -1.3 -1.3
0049 -0.4 1.7 0.1 -0.1 -0.2 -0.3 1.2 2.2 -0.4 -0.4 -0.4 -0.4 0.5 -0.4 -0.4 -0.4 -0.4 -0.4 -0.1 -0.4
0050 1 -0.2 2 3 1.7 1 -0.8 0 -0.8 -0.8 -0.8 -0.8 -0.8 -0.8 -0.8 -0.6 0 -0.8 -0.6 -0.3
0051 0.7 -0.6 -0.6 0.1 -0.4 -0.4 -0.6 -0.1 0.5 1.6 0.7 0.6 -0.5 0.3 0.6 1 0.3 0.4 -1.3 -1.3
0052 1.2 -0.5 -0.1 0.9 1 -0.4 -1.3 -0.3 0.3 0.9 0.1 -0.5 -0.4 -0.2 0.7 1.1 1.1 -0.2 -1.3 -1.3
0053 1.6 -0.8 -0.9 -0.4 0.6 -0.4 -1 -0.2 -0.6 -0.3 0.2 -0.1 0.3 0.3 1.2 1.4 0.4 1.4 -0.9 -1
0054 -0.6 1.6 -0.1 1.1 -0.6 0.5 -0.1 3.2 -0.6 -0.5 -0.6 -0.3 -0.1 -0.3 -0.3 -0.2 -0.6 -0.6 -0.6 -0.6
0055 0.7 -0.9 -1 -1.1 -0.6 -1.1 -1.1 -1 1.3 0.4 0.4 0.7 0.8 0.8 1.1 1.5 0.1 1.7 -1.1 -1.1
0056 0.1 2.6 0.6 0.6 0.1 0.3 0.3 1 -0.5 -0.5 -0.5 -0.5 -0.5 -0.5 -0.5 -0.1 -0.4 -0.5 -0.5 -0.5
0057 0.2 0 -0.9 0.2 -0.5 -0.9 -0.8 0.5 0.9 0.7 1.1 0.5 0 0.8 0.3 0.9 0.5 -0.5 -0.8 -1.3
0058 0.5 -0.1 -0.2 -0.5 0.6 -1.2 0 1 -0.3 -0.1 0.6 0.3 0.4 0.3 -0.4 0.6 0.5 -1 1.2 -1.4
0059 1 -1 -0.8 -1.2 -0.2 -1.1 -0.2 -0.6 0.8 0.7 0.7 0.1 0.2 0.4 -0.1 2.1 0.3 1.8 -0.7 -1.2
0060 -0.5 0.2 -0.5 0.2 -0.8 -0.8 -0.4 -0.2 1.3 0.4 -0.1 0.1 1.1 1.7 0.9 -0.3 -0.1 -0.7 -0.8 -0.8
- A F I L V M W Y D E K R H N Q S T G P C
0061 0.2 -0.4 1.3 1 0.7 0.5 -0.1 -0.8 -0.8 -0.2 0.4 1.4 -0.7 -0.5 0.3 -0.5 0.1 -0.8 -0.8 -0.2
0062 0.9 -0.1 0.1 -0.4 0.4 -0.4 0.1 -0.4 -0.4 -0.4 -0.2 -0.2 -0.1 -0.4 -0.4 0.4 0.3 1.1 -0.4 -0.4
Select residue pair below:
i_j Score Prob
0051_0057 3.425 1.00
0038_0048 3.257 1.00
0006_0047 3.125 1.00
0058_0061 3.121 1.00
0045_0048 3.000 1.00
0009_0045 2.716 1.00
0006_0058 2.680 1.00
0002_0050 2.464 1.00
0002_0061 1.941 1.00
0015_0030 1.801 1.00
0038_0041 1.681 1.00
0009_0043 1.619 1.00
0031_0039 1.543 1.00
0002_0058 1.515 1.00
0001_0050 1.457 1.00
0057_0060 1.361 0.99
0048_0051 1.355 0.99
0035_0053 1.352 0.99
0033_0037 1.304 0.99
0010_0034 1.250 0.99
0035_0052 1.189 0.98
0049_0054 1.167 0.97
0019_0022 1.160 0.97
0048_0052 1.140 0.97
0019_0023 1.038 0.94
0021_0025 1.002 0.92
0002_0057 0.997 0.92
0020_0023 0.985 0.92
0005_0049 0.977 0.91
0047_0058 0.963 0.90
0007_0047 0.954 0.90
0001_0005 0.910 0.87
0026_0029 0.882 0.84
0011_0043 0.871 0.83
0023_0030 0.838 0.80
0018_0022 0.836 0.80
0001_0061 0.830 0.79
0025_0030 0.772 0.72
0030_0042 0.764 0.71
0036_0044 0.739 0.67
0047_0051 0.738 0.67
0015_0019 0.733 0.66
0009_0041 0.732 0.66
0051_0055 0.717 0.63
0026_0030 0.712 0.63
0005_0050 0.704 0.61
0010_0031 0.700 0.61
0015_0061 0.697 0.60
0020_0024 0.681 0.57
0007_0010 0.679 0.57
0030_0034 0.678 0.57
0046_0062 0.674 0.56
0053_0056 0.671 0.56
0003_0010 0.669 0.55
0019_0025 0.667 0.55
0031_0052 0.662 0.54
0010_0035 0.656 0.53
0018_0023 0.652 0.53
0015_0042 0.646 0.52
0018_0033 0.627 0.48
0025_0029 0.626 0.48
0032_0049 0.614 0.46
0008_0033 0.612 0.46
0034_0053 0.611 0.46
0011_0042 0.605 0.45
0041_0048 0.586 0.41
0033_0060 0.583 0.41
0032_0040 0.577 0.40
0006_0061 0.568 0.38
0043_0052 0.560 0.37
0002_0060 0.552 0.36
0019_0024 0.546 0.35
0021_0024 0.544 0.35
0034_0037 0.542 0.34
0026_0059 0.542 0.34
0002_0010 0.539 0.34
0005_0037 0.535 0.33
0014_0026 0.526 0.32
0003_0061 0.522 0.31
0036_0062 0.521 0.31
0003_0034 0.520 0.31
0022_0062 0.516 0.30
0003_0056 0.515 0.30
0015_0034 0.506 0.29
0014_0024 0.504 0.29
0056_0062 0.504 0.29
0014_0018 0.503 0.28
0012_0032 0.498 0.28
0033_0044 0.489 0.27
0031_0035 0.488 0.26
0018_0028 0.485 0.26
0024_0028 0.485 0.26
Local Interactions:
i_j Score Prob
0008_0010 3.131 1.00
0020_0021 2.443 1.00
0041_0043 2.324 1.00
0028_0029 2.135 1.00
0057_0059 2.025 1.00
0045_0047 1.963 1.00
0029_0031 1.861 1.00
0006_0007 1.852 1.00
0001_0002 1.627 1.00
0027_0028 1.480 1.00
0016_0017 1.431 1.00
0033_0034 1.360 0.99
0021_0023 1.326 0.99
0023_0024 1.280 0.99
0050_0051 1.254 0.99
0003_0004 1.230 0.98
0023_0025 1.209 0.98
0055_0057 1.205 0.98
0011_0013 1.199 0.98
0024_0025 1.194 0.98
0024_0026 1.184 0.98
0019_0021 1.148 0.97
0042_0043 1.141 0.97
0007_0008 1.116 0.96
0053_0054 1.108 0.96
0043_0045 1.012 0.93
0038_0039 1.012 0.93
0059_0060 1.012 0.93
0038_0040 1.005 0.93
0060_0062 1.002 0.92
0009_0011 0.986 0.92
0034_0035 0.948 0.89
0051_0052 0.935 0.89
0026_0028 0.913 0.87
0013_0014 0.828 0.79
0040_0042 0.785 0.73
0025_0026 0.760 0.70
0022_0023 0.728 0.65
0054_0056 0.696 0.60
0007_0009 0.678 0.57
0055_0056 0.634 0.49
0029_0030 0.634 0.49
0027_0029 0.613 0.46
0059_0061 0.607 0.45
0022_0024 0.607 0.45
0019_0020 0.604 0.44
0044_0045 0.599 0.43
0010_0011 0.592 0.42
0004_0005 0.588 0.42
0037_0038 0.571 0.39
0054_0055 0.570 0.39
0026_0027 0.558 0.37
0052_0053 0.535 0.33
0033_0035 0.485 0.26
See all coupling residues
Download raw data
Renumber residues to start with:
Position: 1 2 3 4 5 ...
Sequence: M V N E F ...
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