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Tatiana Brailovskaya Return to Main Page
Instructions
  • Use the menu to the right to browse the coupling matrix, or select a position from the PSSM below to see what it is coupled with.
Conservation matrix (aka PSSM)
- A F I L V M W Y D E K R H N Q S T G P C
0001 0.1 -0.6 -0.8 0.1 -0.5 -0.3 -0.8 0.2 0.6 1.3 0.6 -0.4 -0.3 -0.1 0 0.3 0.1 0.8 0.7 -0.5
0002 -0.1 -0.8 -0.1 0.3 0.2 -0.6 -0.8 -0.3 1.4 2 0.3 -0.3 -0.1 0 -0.3 0.2 0.5 -0.1 0 -0.3
0003 -0.2 -0.2 -0.2 0.5 1.1 -0.6 -0.6 -0.6 0.5 1.3 -0.2 -0.3 -0.4 0.3 -0.1 0.3 0.4 0.3 0.1 -0.8
0004 -0.2 0.2 0.4 0 0.2 0.1 -0.2 0.2 -0.2 0 -0.2 0.1 0 -0.2 0.1 -0.2 0.2 0.2 -0.2 -0.2
0005 0.3 -0.4 0.3 -0.3 0.8 -0.6 -0.6 -0.6 -0.1 1.6 0.5 -0.2 -0.1 -0.2 0.4 0.5 0.5 -0.3 -0.6 -0.4
0006 -0.1 0.5 0 0.4 0.2 0 -0.1 0.3 -0.3 0.1 0.1 -0.1 0.3 -0.3 -0.3 0 0.3 -0.3 -0.1 -0.2
0007 0.4 0.1 -0.2 -0.2 -0.2 -0.2 -0.2 -0.2 -0.2 0.9 -0.2 -0.2 -0.2 -0.2 1.9 0.1 -0.2 0.1 -0.2 -0.2
0008 2.1 -0.5 -0.5 -0.5 -0.1 -0.3 -0.5 -0.3 0 -0.5 0.6 0.5 0.1 -0.1 -0.1 1.1 -0.3 0.8 -0.5 -0.5
0009 0.9 -0.7 -0.7 -0.5 -0.7 -0.7 -0.7 -0.7 1.5 1.2 -0.2 0.1 -0.7 1.3 0.3 -0.2 0.3 1.9 -0.5 -0.5
0010 -0.1 -0.1 -0.6 -0.6 0 -0.6 -0.6 -0.2 0.6 1.1 -0.4 -0.2 -0.6 0.3 0.6 1 0.8 0.3 0.3 -0.4
0011 0.2 -0.5 -0.2 -0.5 -0.5 -0.8 -0.8 -0.2 1.6 1.1 -0.8 -0.1 -0.5 1 -0.3 0 0.8 0.7 0.7 -0.1
0012 0.1 -0.2 0.5 0.2 0.5 0.4 -0.2 0.2 -0.2 -0.2 -0.2 -0.2 -0.2 -0.2 -0.2 0.1 -0.2 -0.2 -0.2 0.3
0013 -0.1 0 0.1 -0.1 -0.2 -0.3 -0.4 0 -0.2 0.2 0.8 0.4 0.1 -0.1 0.6 -0.1 0.5 0 -0.4 -0.4
0014 0.2 0.8 0.3 0.3 0.2 -0.3 -0.3 0.4 -0.3 -0.3 -0.3 -0.3 0.5 -0.3 -0.1 0.1 0.1 -0.3 -0.1 0
0015 0.4 -0.1 -0.1 -0.1 -0.1 -0.1 -0.1 -0.1 -0.1 0.9 -0.1 -0.1 -0.1 -0.1 0.9 -0.1 -0.1 -0.1 -0.1 -0.1
0016 0.8 -0.3 -0.3 0 -0.3 0 -0.3 -0.3 -0.3 -0.3 -0.3 -0.3 -0.3 0 0.1 1.3 0 1.2 -0.3 0.2
0017 1.1 -0.4 0.3 1.6 1.1 0.3 -0.4 -0.4 -0.4 -0.4 -0.1 -0.4 -0.4 -0.2 -0.4 0.2 0.4 0.1 -0.4 -0.4
0018 0.2 -0.6 -0.6 -0.6 -0.3 -0.6 -0.6 -0.6 0.7 1.2 -0.3 0.4 0.3 1.3 0.8 0.8 0.1 -0.6 -0.4 -0.3
0019 1.1 0.7 -0.3 0.4 0.1 -0.3 -0.5 0.5 -0.5 -0.5 -0.5 -0.5 0.4 -0.5 -0.3 0.4 1.4 -0.5 -0.5 0.8
0020 -0.1 0.1 0.6 0.7 0.2 0.1 -0.1 -0.1 -0.1 0.1 0.1 -0.1 -0.1 -0.1 -0.1 -0.1 -0.1 -0.1 -0.1 -0.1
0021 -0.5 -0.3 -0.1 0.4 0.7 0.3 -0.5 0.6 -0.5 0.7 -0.5 0.1 0.6 -0.3 1.1 -0.2 0.2 -0.5 -0.5 -0.3
0022 -0.3 0.7 0 0.8 0 -0.3 -0.3 0.8 -0.3 -0.3 0.1 -0.3 0.4 -0.3 0 0.2 -0.3 -0.3 -0.3 0
0023 -0.2 -0.2 -0.2 -0.2 -0.2 -0.2 -0.2 -0.2 -0.2 1.3 -0.2 -0.2 0.4 -0.2 2.4 -0.2 -0.2 -0.2 -0.2 -0.2
0024 0.5 -0.2 -0.5 -0.5 -0.5 -0.2 -0.5 -0.5 0.2 -0.2 0 -0.5 -0.5 1.2 -0.5 2.2 0.8 1.1 -0.2 -0.5
0025 -0.4 -0.3 -0.2 -0.1 -0.3 0.4 -0.8 -0.5 0.4 0.9 1.3 0 -0.1 0.8 0.3 0.8 -0.3 0.1 -0.8 -0.5
0026 -0.3 -0.6 -0.3 -0.6 -0.3 0 -0.6 -0.1 0.8 1.9 0.4 -0.2 0 0.3 0.6 0.6 0.3 -0.3 -0.3 -0.6
0027 0 -0.7 -0.1 0 -0.1 -0.2 -0.7 -0.2 0.5 1.1 0.1 0 0.1 -0.2 -0.4 0.8 0.8 0 0.4 -0.5
0028 0.1 0.4 0.6 -0.2 1 0.1 -0.2 0.1 -0.2 -0.2 -0.2 -0.2 0.1 -0.2 -0.2 -0.2 -0.2 -0.2 -0.2 -0.2
0029 0.3 -0.3 0 -0.7 -0.2 -0.4 -0.7 0 0 1.1 0.7 0.4 0.3 -0.1 0.1 1.1 1 -0.7 -0.7 -0.5
0030 0 0.8 -0.3 0.7 0.3 0 -0.3 0.5 -0.3 0 -0.3 -0.3 0.5 -0.3 -0.3 -0.3 0.5 -0.1 -0.3 -0.3
- A F I L V M W Y D E K R H N Q S T G P C
0031 -0.1 -0.1 -0.1 -0.1 -0.1 -0.1 -0.1 -0.1 -0.1 1.3 0.1 -0.1 -0.1 -0.1 0.3 -0.1 -0.1 0.1 -0.1 -0.1
0032 1.5 -0.3 -0.3 -0.3 0.4 0 -0.3 -0.3 -0.3 -0.3 0.3 -0.3 0 -0.3 0 0.2 -0.3 1.4 -0.3 -0.3
0033 -0.1 -0.7 0 0.1 0.2 -0.7 -0.7 -0.5 0.7 1.3 1.2 0 0 0.2 -0.7 0.9 0.7 -0.1 -0.5 -0.7
0034 0.1 0.1 -0.1 0.1 -0.1 -0.5 -0.7 -0.3 0.9 1.9 -0.3 -0.7 -0.5 0.4 0.2 0.7 0.1 0.1 -0.1 -0.7
0035 0.1 -0.5 0 0 0 -0.6 -0.8 -0.1 0.8 0.8 -0.1 0 -0.3 -0.3 0.5 0.7 0.5 0.4 0.1 -0.6
0036 0.5 0.3 0.8 0.3 0.8 0 -0.2 -0.2 -0.2 -0.2 -0.2 -0.2 -0.2 -0.2 -0.2 0 0.2 -0.2 -0.2 -0.2
0037 1 -0.1 -0.3 -0.7 0.6 -0.8 -0.8 -0.3 0.9 2 -0.1 0.1 -0.1 -0.3 0.1 0.5 1 0 -0.8 -0.8
0038 0.1 0.6 -0.3 0.6 0.5 0 -0.1 0.2 -0.3 0.3 -0.3 -0.3 0.4 -0.3 -0.3 0 0.5 -0.3 -0.1 -0.3
0039 -0.3 -0.3 -0.3 -0.3 -0.3 -0.3 -0.3 -0.3 -0.3 3.4 -0.3 -0.3 -0.3 0 1.9 -0.3 -0.3 0 -0.3 -0.3
0040 1.3 -0.5 -0.5 -0.5 0.1 0.1 -0.5 -0.5 0.1 -0.5 -0.5 -0.5 -0.2 0.2 -0.5 2.2 -0.1 1.7 -0.5 -0.5
0041 -0.3 -0.6 -0.1 0.1 -0.2 0 -0.6 -0.6 1.2 0.6 -0.2 -0.6 -0.1 0.5 0.3 1.2 0.3 0.8 -0.2 -0.8
0042 -0.5 -0.5 0 0.9 -0.5 0 -0.7 -0.7 1.4 1.2 -0.2 -0.7 -0.7 0.9 0.1 0.1 1 0.2 -0.7 0
0043 0.8 0.6 -0.6 0.6 -0.4 -0.6 -0.6 -0.2 0.1 1.1 -0.9 -0.4 -0.4 0 0 1.2 0.6 0.1 0.6 -0.9
0044 -0.2 0.2 0.6 0.4 0.2 0.1 0.2 -0.2 -0.2 0 -0.2 -0.2 -0.2 0 -0.2 -0.2 -0.2 0 -0.2 0.3
0045 0 0.2 -0.5 -0.5 0.5 -0.7 -0.7 0.9 -0.2 1 0.1 0.5 -0.5 -0.3 0.5 0.7 0.1 -0.1 -0.5 0.2
0046 0.6 1 -0.3 0.5 0.3 -0.1 -0.1 -0.1 -0.8 1.8 -0.8 -0.3 0.7 -0.1 -0.6 0.3 1.2 -0.8 -0.6 -0.6
0047 -0.3 -0.3 -0.3 -0.3 -0.3 -0.3 -0.3 -0.3 -0.3 1.3 -0.3 0 0.1 -0.3 3.1 0.3 -0.3 -0.3 -0.3 -0.3
0048 0.8 -0.4 -0.4 -0.4 -0.1 0.6 -0.4 -0.4 0.1 -0.4 -0.1 -0.1 0 0.3 -0.2 1 0.2 0.6 -0.4 -0.1
0049 -0.1 -0.1 -0.1 -0.5 -0.1 -0.4 -0.7 -0.3 1.1 0.6 -0.7 -0.4 -0.5 -0.1 -0.1 0.5 0.6 0.2 0.5 0
0050 0.2 0 -0.1 1 0.1 -0.4 -0.7 0.2 0.9 0.7 -0.3 -0.4 -0.7 0.2 -0.1 -0.3 0.4 -0.4 -0.5 -0.5
0051 -0.7 -0.1 0.1 -0.3 0.3 -0.3 -0.5 0.2 0.5 1.2 0 0.2 -0.4 -0.2 -0.3 0.5 0.3 -0.5 -0.5 0.2
0052 0.1 0.3 0.4 0.1 -0.6 -0.1 -0.1 -0.1 -0.1 -0.1 -0.1 -0.1 -0.1 -0.1 -0.1 0.1 0.1 0.1 -0.1 0.3
0053 0 0.2 -0.2 0 0.6 -0.4 -0.3 0.9 -0.2 0.4 -0.3 0.3 0.1 -0.6 -0.6 0.8 -0.3 -0.6 -0.6 -0.1
0054 0 0.2 -0.3 0.7 0.6 -0.3 -0.3 0.4 -0.3 -0.3 -0.3 -0.3 0.1 -0.3 0.2 -0.3 0 -0.3 0 -0.3
0055 0.4 -0.2 -0.2 -0.2 -0.2 -0.2 -0.2 -0.2 -0.2 0.7 -0.2 -0.2 -0.2 -0.2 1.6 0.3 -0.2 -0.2 -0.2 -0.2
0056 1.6 -0.3 -0.3 0 -0.1 -0.3 -0.3 -0.3 0 -0.3 -0.3 -0.1 -0.3 0.1 0 1.6 -0.3 0.3 -0.3 -0.3
0057 -0.1 -0.1 0.3 -0.6 0.3 -0.3 -0.6 -0.6 -0.2 0 0.3 0.3 -0.2 -0.1 -0.3 0.9 0.4 -0.1 -0.3 -0.2
0058 -0.1 -0.6 0 0.1 -0.6 0.2 -0.6 -0.3 0.5 0.4 -0.3 0.8 -0.6 0.2 0.2 1.1 0.6 0.3 -0.6 -0.2
0059 -0.2 -0.7 -0.7 -0.7 0.2 -0.7 -0.7 -0.4 0.3 1 0.3 -0.1 -0.2 0 0 2 2.1 -0.2 -0.7 0
0060 -0.3 -0.5 1.2 1.9 0.2 1.2 -0.5 -0.5 -0.5 -0.5 -0.5 -0.5 -0.5 -0.5 0.1 0 1.4 -0.2 -0.5 -0.2
- A F I L V M W Y D E K R H N Q S T G P C
0061 0.3 -0.3 -0.3 0 -0.3 -0.3 -0.3 -0.3 -0.3 -0.3 0.1 -0.3 -0.3 -0.3 -0.3 0.6 3 0.3 -0.3 -0.3
0062 -0.3 -0.5 -0.2 -0.2 0.5 -0.5 -0.5 -0.5 0.4 0.1 1.8 0.2 -0.5 0.9 0.8 -0.2 0.1 -0.3 -0.5 -0.5
0063 0.6 -0.1 -0.5 -0.1 -0.1 -0.5 -0.5 -0.2 0.9 0.6 -0.1 0.1 0.1 0.5 -0.2 0.2 -0.5 -0.3 0.6 -0.5
0064 -0.3 -0.3 -0.3 -0.3 -0.3 -0.3 -0.3 -0.3 -0.3 -0.3 -0.3 -0.3 -0.3 -0.3 -0.3 -0.3 -0.3 4.9 -0.3 -0.3
0065 -0.4 0.2 -0.4 -0.4 -0.1 -0.1 -0.4 0.4 1.2 0.3 -0.4 -0.4 0.4 0.3 1 0.2 -0.4 -0.4 -0.4 -0.1
0066 -0.3 -0.3 -0.3 -0.3 -0.3 -0.3 -0.3 -0.3 -0.3 -0.3 -0.3 -0.3 -0.3 -0.3 -0.3 -0.3 -0.3 -0.3 -0.3 4.9
0067 0 -0.2 -0.2 -0.2 0.2 -0.2 -0.2 -0.2 -0.2 -0.2 -0.2 -0.2 -0.2 0.2 -0.2 1.1 0.6 0.6 -0.2 0.2
0068 0.5 -0.1 0.2 0.2 -0.1 0.1 -0.1 -0.1 -0.1 -0.1 -0.1 -0.1 -0.1 -0.1 -0.1 -0.1 -0.1 0.8 0.1 -0.1
0069 1.4 -0.4 -0.1 -0.4 0.1 0.3 -0.4 -0.4 -0.4 -0.4 0.1 0 -0.1 -0.4 -0.1 0.4 0.5 0.9 -0.4 0
0070 0.6 -0.2 0.1 -0.1 0.3 -0.5 -0.5 -0.5 0.4 -0.5 -0.5 -0.1 0.3 0.9 -0.2 1.2 0.2 0.1 -0.5 -0.5
0071 -0.4 0.4 0.5 0.3 0.6 0.3 -0.6 -0.6 0 -0.3 -0.1 0 -0.1 0.7 0 0.2 1 -0.6 -0.6 -0.4
0072 0.3 -0.8 -0.6 -0.6 0.4 -0.6 -0.8 -0.3 1 0.2 0.1 0.6 -0.2 1.1 0.1 0.4 0.8 0 -0.8 -0.3
0073 -0.3 -0.3 -0.6 -0.4 0.1 -0.3 -0.6 -0.3 0 -0.6 0.3 -0.3 0 1.6 0.4 1.1 1 0.5 -0.6 -0.6
0074 0.9 -0.3 -0.6 -0.6 -0.3 -0.6 -0.6 -0.4 -0.1 -0.6 -0.6 -0.3 -0.3 0.4 -0.6 2.5 0.8 1.7 0.9 -0.6
0075 -0.3 0.1 0.7 1.5 0.9 0.5 -0.3 -0.3 -0.3 -0.3 -0.3 -0.3 0 0 -0.3 0.2 -0.3 -0.3 -0.3 -0.3
0076 -0.2 -0.6 0 -0.3 -0.3 0 -0.6 -0.1 0 0.5 1 0.1 0.1 1.7 0 0.3 0 -0.6 -0.3 -0.3
0077 0.1 -0.3 1.1 0.8 0.7 -0.3 -0.3 -0.3 -0.3 -0.1 0 0 -0.3 -0.3 -0.3 0 0 -0.3 0.2 -0.3
0078 -0.3 -0.5 0.4 -0.1 1.4 -0.7 -0.2 -0.7 -0.5 -0.3 0.9 0.3 0.6 -0.1 0.8 0 0.8 -0.7 -0.5 -0.7
0079 0.4 -0.7 -0.7 -0.4 -0.7 -0.2 -0.4 -0.7 1.5 1.5 0.5 0.1 -0.7 0.6 0.2 0.7 0.1 -0.4 -0.7 -0.7
0080 0.2 -0.4 -0.4 -0.2 -0.4 -0.4 -0.4 -0.4 1.1 0.6 0.1 -0.4 -0.4 0.6 -0.1 1.4 -0.2 0.6 -0.4 -0.4
0081 1.3 -0.7 -0.5 -0.5 0 -0.7 -0.7 -0.5 -0.7 -0.2 1.6 0.2 -0.5 -0.5 2.2 -0.5 1.5 -0.2 -0.5 -0.7
Select residue pair below:
i_j Score Prob
0014_0022 2.424 1.00
0038_0054 2.413 1.00
0022_0030 2.340 0.99
0014_0054 2.268 0.99
0022_0054 2.258 0.99
0014_0030 2.240 0.99
0030_0054 2.215 0.99
0020_0028 1.974 0.97
0006_0014 1.895 0.96
0006_0030 1.841 0.96
0016_0032 1.766 0.94
0006_0038 1.764 0.94
0006_0022 1.698 0.92
0030_0038 1.691 0.92
0014_0038 1.637 0.90
0006_0054 1.609 0.89
0012_0052 1.604 0.89
0022_0038 1.581 0.88
0044_0047 1.477 0.83
0020_0068 1.334 0.74
0004_0020 1.245 0.66
0028_0068 1.195 0.61
0034_0042 1.164 0.58
0012_0036 1.124 0.54
0020_0052 1.122 0.54
0036_0052 1.122 0.54
0020_0036 1.112 0.53
0008_0027 1.098 0.52
0004_0036 1.096 0.52
0028_0036 1.085 0.50
0028_0044 1.084 0.50
0024_0058 1.040 0.46
0028_0052 1.038 0.46
0004_0028 1.034 0.45
0004_0068 1.023 0.44
0040_0060 1.010 0.43
0051_0078 1.006 0.42
0012_0020 1.005 0.42
0061_0068 0.983 0.40
0052_0055 0.953 0.37
0012_0028 0.948 0.37
0014_0067 0.942 0.36
0030_0067 0.940 0.36
0044_0052 0.936 0.36
0016_0031 0.934 0.36
0004_0044 0.931 0.35
0020_0044 0.929 0.35
0039_0052 0.928 0.35
0021_0071 0.926 0.35
0005_0073 0.922 0.34
0052_0068 0.919 0.34
0012_0044 0.911 0.33
0040_0065 0.898 0.32
0026_0050 0.893 0.32
0013_0063 0.883 0.31
0025_0059 0.879 0.31
0065_0077 0.859 0.29
0005_0041 0.846 0.28
0054_0067 0.831 0.27
0045_0053 0.830 0.27
0049_0056 0.822 0.26
0006_0067 0.822 0.26
0068_0075 0.817 0.26
0020_0075 0.814 0.25
0021_0069 0.814 0.25
0017_0070 0.811 0.25
0052_0077 0.803 0.25
0057_0078 0.789 0.23
0027_0035 0.788 0.23
0053_0080 0.787 0.23
0013_0045 0.782 0.23
0004_0052 0.780 0.23
0031_0048 0.777 0.23
0031_0071 0.771 0.22
0021_0074 0.769 0.22
0013_0069 0.765 0.22
0038_0067 0.760 0.21
0015_0023 0.759 0.21
0022_0067 0.752 0.21
0004_0007 0.751 0.21
0015_0020 0.750 0.21
0031_0055 0.741 0.20
0010_0026 0.739 0.20
0013_0029 0.736 0.20
0005_0079 0.728 0.19
0048_0056 0.727 0.19
0010_0033 0.725 0.19
0057_0080 0.724 0.19
0019_0031 0.721 0.19
0062_0069 0.717 0.19
0023_0063 0.716 0.19
0004_0012 0.707 0.18
0044_0068 0.706 0.18
0015_0031 0.703 0.18
0031_0069 0.691 0.17
0009_0035 0.691 0.17
0013_0053 0.689 0.17
0012_0077 0.686 0.17
0017_0077 0.667 0.16
0016_0070 0.660 0.15
0032_0048 0.659 0.15
0007_0015 0.659 0.15
0013_0065 0.657 0.15
0008_0029 0.653 0.15
0019_0062 0.652 0.15
0018_0062 0.648 0.15
0036_0068 0.648 0.15
0001_0049 0.643 0.15
0026_0033 0.642 0.14
0057_0073 0.641 0.14
0063_0069 0.640 0.14
0007_0076 0.631 0.14
0067_0080 0.630 0.14
0057_0072 0.626 0.14
0021_0080 0.625 0.14
0012_0075 0.624 0.14
0024_0048 0.623 0.14
0008_0058 0.622 0.13
0018_0060 0.622 0.13
0073_0079 0.622 0.13
0053_0071 0.621 0.13
Local Interactions:
i_j Score Prob
0050_0051 0.912 0.34
0052_0054 0.763 0.22
0055_0056 0.712 0.18
0065_0067 0.704 0.18
0031_0032 0.696 0.17
0001_0003 0.681 0.17
0010_0011 0.676 0.16
0004_0006 0.629 0.14
See all coupling residues
Download raw data
Renumber residues to start with:
Position: 1 2 3 4 5 ...
Sequence: K E R I Q ...
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