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Instructions
  • Use the menu to the right to browse the coupling matrix, or select a position from the PSSM below to see what it is coupled with.

Conservation matrix (aka PSSM)
- A F I L V M W Y D E K R H N Q S T G P C
0001 0.3 -0.8 -0.8 -0.6 0.1 -0.8 -0.8 -0.7 1 1 -0.7 -0.3 -0.5 -0.5 -0.2 0.2 -0.3 1.4 0.3 -0.8
0002 0.7 -0.4 -0.5 0 0 -0.2 -1 -0.5 0.2 1.1 -0.2 0.1 -0.6 0.3 0.1 0.2 0 0.3 1.7 -0.8
0003 -0.2 0.3 0 1.1 0.3 0.7 -0.5 -0.5 -0.2 0.3 -0.7 -0.2 -0.5 -0.1 -0.2 0.3 0.2 0.1 -0.3 -0.2
0004 0.4 0.1 -0.4 0.5 -0.2 -0.4 -0.5 -0.4 -0.1 -0.6 -0.3 0.2 -0.2 -0.4 -0.1 0.6 -0.1 0.4 1.4 -0.2
0005 0.3 -0.1 -0.5 0.5 0.2 -0.9 -1.1 0 0.5 0.5 -0.3 0.1 0 -0.3 0 0.6 0.4 -0.3 1.3 -0.7
0006 0.3 0 -0.5 -0.4 -0.6 -0.4 -0.8 -0.5 0.2 0 0.3 0.5 -0.1 0.4 0.2 0.7 0 1 0.2 -0.6
0007 0.4 0.6 -0.3 0.6 0.3 -0.5 1.1 0.3 -0.5 -0.2 -0.1 -0.5 -0.5 -0.3 -0.1 -0.1 -0.1 0.1 -0.3 -0.3
0008 0.1 -0.8 0 0.1 0.2 -0.2 -0.8 -0.2 0.2 1.2 0.8 -0.4 -0.5 -0.2 0.3 0.9 0.3 -0.5 -0.8 -0.3
0009 1 -0.9 0.7 0.3 0.8 1.3 -1 -0.6 -1 1.6 0.3 0.8 -0.8 -1 0.8 0.2 0.1 -0.9 -0.4 -0.5
0010 0.7 -0.5 -0.1 -0.1 0 -0.2 -1 -0.4 -0.2 0.3 0.6 0.9 -0.1 -0.2 0.8 0.4 -0.1 0.4 -0.4 -0.1
0011 -0.1 0.8 0.6 0.8 0.9 -0.1 -0.5 0.5 -0.5 -0.2 0 0.3 -0.4 -0.8 -0.3 0.3 0.6 -0.6 -0.4 -0.1
0012 0.3 -0.4 -0.2 -0.2 0.1 -0.7 -0.9 -0.5 1.6 -0.1 0.1 -0.1 -0.2 0 -0.3 1.2 1.6 -0.7 -0.2 -0.6
0013 0.2 -0.7 -0.2 0 0 -0.7 -1.1 -0.9 0.9 0.6 0.1 0.2 0.2 0.2 0.1 0.9 0.3 0.2 1.1 -1.1
0014 -0.5 -0.2 -0.8 0.4 0 -0.6 -1.2 -0.5 1.4 0.5 0.5 0 -0.3 1.1 0.1 1.2 0.8 0.1 -0.6 -1
0015 0.7 -0.1 -0.8 -0.1 -0.1 -0.8 -0.8 -0.6 0.2 -0.5 -0.1 0.5 -0.2 1.2 0.3 0.8 -0.8 2.6 -0.5 -0.8
0016 -0.6 -0.1 -0.5 0.6 -0.1 -0.7 0.1 0.2 -0.2 0.4 0.5 1 -0.1 0.3 0.5 0 0.1 -0.5 -0.1 -0.5
0017 -0.6 -0.4 1 0.9 1.6 -0.2 -0.4 -0.1 -0.9 -0.8 0.6 0.6 -0.5 -0.5 -0.6 0.2 0.8 -1.1 0.8 -0.4
0018 0.1 1.1 -0.5 0.8 0 -0.5 -0.5 0.8 0 0.4 0.2 -0.3 0.2 -0.2 -0.2 -0.3 -0.3 -0.1 -0.5 0.1
0019 -0.3 0.9 0.3 0.5 -0.1 -0.1 -0.6 1.5 -0.1 -0.1 0.1 -0.3 0 0.1 -0.3 -0.2 -0.1 -0.6 -0.3 -0.3
0020 0.4 0 1.1 1.3 0.7 -0.2 -0.8 0.6 -0.5 -0.5 -0.4 -0.5 -0.3 -0.8 -0.5 0.5 0.7 -0.4 -0.3 0.1
0021 0.2 -0.5 0.1 -0.3 -0.5 -0.5 -0.7 -0.7 1 -0.1 0.6 -0.1 0.7 1.4 -0.4 0.4 -0.1 0 0.1 -0.7
0022 0 0 0 0.3 0 -0.8 -0.8 -0.1 0.2 -0.2 -0.3 0.8 1 -0.3 -0.2 1.1 0.8 -0.3 -0.4 -0.5
0023 0.3 -0.2 0.8 0.2 0.7 -0.5 -1 -0.7 -0.3 0.6 0.4 0.4 -0.5 0.7 0 0.5 0.3 -0.2 0.1 -1
0024 0.7 -0.8 -0.2 0.3 -0.4 -0.9 -1.1 -0.8 0 1 -0.4 0.1 -0.1 0.9 0.3 1.4 1.8 -0.5 -0.1 -0.8
0025 0 -0.1 -0.8 0.3 -0.4 -0.4 -1 -0.8 -0.2 0.1 1.6 1.7 0.3 0.2 0.8 0.3 -0.7 0.5 -0.6 -0.7
0026 0.2 0.1 1 0.1 0.5 -0.2 -1 -1 -0.9 -0.2 0.7 0.9 -0.5 -0.4 -0.3 1.5 1.6 -0.6 -0.5 -0.8
0027 -0.1 0 0.3 0.3 0.5 -0.2 -0.3 -0.3 0.1 -0.6 -0.4 0.5 -0.1 0.1 -0.1 1 -0.3 0.1 0.1 -0.6
0028 0 -0.5 -0.1 0.1 -0.2 -0.5 -0.5 0 -0.5 -0.3 0.3 0.2 0.3 0.2 0.7 1.3 1 -0.1 -0.5 -0.7
0029 -0.2 0.5 -0.6 0.5 0.1 -0.5 1.2 0.7 -0.3 -0.4 -0.4 -0.1 -0.3 -0.1 0.4 0.1 -0.6 -0.1 0.2 -0.3
0030 -0.1 0.2 0.6 0.5 0 -0.6 -0.8 -0.2 0 0.2 0.4 -0.3 -0.1 0.5 0.6 0.8 0.9 -0.4 -0.8 -0.7
- A F I L V M W Y D E K R H N Q S T G P C
0031 -0.1 -0.3 0.3 0.3 -0.2 -0.5 -0.5 -0.5 -0.2 0.1 0.8 0.3 0.8 -0.2 -0.6 0.5 0 0.1 0.2 -0.1
0032 0.5 -0.3 0.2 -0.1 -0.3 -0.6 -0.6 -0.6 -0.6 -0.1 -0.4 0.6 -0.2 -0.6 -0.3 0.9 0.3 -0.6 2.7 -0.6
0033 0.1 -0.9 -0.4 0.5 0.1 -0.1 -1.1 -1 -0.3 -0.3 0.4 0.7 -0.6 -0.2 0.5 0.7 0.5 0.5 0.2 -0.1
0034 -0.1 0 0.3 1.5 0.5 -0.7 -0.9 -0.6 -0.4 0.2 -0.3 0.6 -0.7 0.1 -0.5 0.3 0.9 0.3 -0.1 -0.7
0035 -0.4 -0.9 -0.7 -0.8 -0.4 -0.6 -0.9 -0.9 -0.6 -0.5 0.8 0.3 -0.2 0 -0.1 0.4 -0.1 1.4 1.4 -0.9
Select residue pair below:
i_j Score Prob
0021_0024 2.626 1.00
0011_0017 2.531 1.00
0003_0006 2.347 1.00
0010_0020 2.344 1.00
0009_0017 2.149 1.00
0030_0034 1.563 1.00
0008_0022 1.408 1.00
0030_0035 1.367 0.99
0014_0017 1.295 0.99
0012_0016 1.286 0.99
0003_0007 1.252 0.99
0004_0007 1.201 0.98
0002_0031 1.158 0.97
0021_0028 1.129 0.97
0005_0011 1.124 0.97
0005_0023 1.116 0.96
0007_0019 1.019 0.93
0016_0030 1.016 0.93
0011_0016 0.986 0.92
0008_0018 0.924 0.88
0019_0031 0.912 0.87
0022_0027 0.893 0.85
0006_0023 0.882 0.84
0016_0020 0.873 0.83
0017_0034 0.858 0.82
0010_0016 0.850 0.81
0012_0018 0.779 0.73
0002_0034 0.735 0.66
0001_0016 0.733 0.66
0025_0029 0.705 0.61
0013_0030 0.698 0.60
0001_0017 0.692 0.59
0002_0035 0.650 0.52
0013_0017 0.645 0.51
0009_0034 0.635 0.50
0002_0030 0.634 0.49
0010_0028 0.629 0.49
0011_0023 0.627 0.48
0027_0032 0.625 0.48
0007_0027 0.625 0.48
0028_0034 0.617 0.47
0001_0009 0.616 0.46
0014_0030 0.616 0.46
0005_0029 0.608 0.45
0008_0020 0.596 0.43
0015_0019 0.588 0.42
0018_0029 0.577 0.40
0013_0029 0.575 0.39
0011_0026 0.574 0.39
0021_0026 0.559 0.37
0015_0018 0.555 0.36
Local Interactions:
i_j Score Prob
0031_0033 6.767 1.00
0003_0004 4.116 1.00
0008_0010 3.598 1.00
0012_0014 2.982 1.00
0021_0023 2.411 1.00
0034_0035 2.102 1.00
0025_0027 2.028 1.00
0021_0022 1.830 1.00
0004_0006 1.644 1.00
0024_0026 1.512 1.00
0023_0024 1.507 1.00
0027_0029 1.505 1.00
0020_0022 1.371 0.99
0013_0014 1.334 0.99
0032_0033 1.224 0.98
0001_0002 1.101 0.96
0027_0028 0.966 0.91
0029_0030 0.965 0.90
0012_0013 0.913 0.87
0018_0019 0.912 0.87
0031_0032 0.844 0.81
0011_0013 0.802 0.76
0011_0012 0.780 0.73
0006_0007 0.668 0.55
0018_0020 0.655 0.53
0009_0011 0.622 0.47
0028_0030 0.613 0.46
0030_0031 0.606 0.45
0014_0016 0.602 0.44
0005_0007 0.586 0.41
0028_0029 0.573 0.39
See all coupling residues
Download raw data
Renumber residues to start with:
Position: 1 2 3 4 5 ...
Sequence: D E L P P ...

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