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Instructions
  • Use the menu to the right to browse the coupling matrix, or select a position from the PSSM below to see what it is coupled with.
Conservation matrix (aka PSSM)
- A F I L V M W Y D E K R H N Q S T G P C
0005 0.5 -0.9 -0.6 -0.9 -0.4 -0.7 -1.1 -1.1 2 2.1 0.2 -0.9 -0.3 0.3 0.8 0.8 -0.2 -0.6 -0.1 -1.1
0006 0.6 -0.9 -0.5 -0.5 0.1 -0.7 -1.1 -1.1 2.1 2.9 0.2 -0.8 -0.7 0 0.8 0 0.6 -0.3 -0.9 -1.1
0007 0.1 -0.4 1.9 1.3 1.3 1.1 -0.9 -0.6 -0.8 -0.2 -0.3 -0.4 -0.5 -0.4 -0.5 -0.3 0.5 -0.8 -0.9 -0.9
0008 -0.1 0.8 0.4 1.1 0.6 -0.5 -1.1 0.3 -0.8 1.1 0.5 0.3 -0.9 -0.5 0.5 0.2 0.2 -0.7 -1.1 -1.1
0009 1.4 -1.1 -0.7 -0.4 -0.5 -0.7 -1.1 -0.9 1.7 2.2 0.4 -0.5 -0.6 -0.1 0.8 0.9 0.7 0.2 -0.3 -1.1
0010 1 -0.4 0.3 0.5 0.4 -0.3 -0.6 -0.6 -0.1 1.1 1 0.8 -0.7 -0.8 0.8 0 0.8 -0.7 -1 -1
0011 -0.2 0.7 1.5 1.6 0.4 0.7 -0.5 -0.3 -0.5 -0.5 -0.5 -0.5 -0.3 -0.5 -0.4 -0.3 0.2 -0.5 -0.5 0.4
0012 0 0 1.1 0.9 1.2 -0.1 -1 -0.3 -1 0.2 1.2 0.7 -0.6 0.3 -0.5 0 0.3 -0.4 -1 -0.2
0013 0.8 -1 -1.1 -0.2 -0.6 -1.1 -1.3 -0.7 1.7 1.7 0.8 0.1 -0.6 0.8 0.4 0.9 1 0.5 -0.6 -1.1
0014 1.2 0.4 2.6 1.9 2 0.3 -0.9 -0.4 -1 -0.6 -1 -0.4 -0.5 -0.6 -0.6 -0.3 0.4 -0.6 -1 -0.6
0015 0.3 0.8 1.7 1.6 1.7 0.3 -0.6 -0.6 -0.4 -0.6 -0.6 -0.6 -0.6 -0.6 -0.4 -0.4 0.3 -0.5 -0.6 -0.1
0016 1.7 -1 -0.6 -0.7 0.2 -0.8 -1.1 -1.1 -0.3 1.1 1.1 0.6 -0.4 0.3 0.4 1 0.5 0.3 -1.1 -0.3
0017 0.6 -1 -0.9 -0.5 -0.6 -1.1 -1.3 -0.9 2 2.5 1.1 0.1 -0.4 0.9 0.3 1 0.2 -0.2 -0.1 -0.9
0018 0 -0.6 0.2 0.1 1 -0.4 -1.1 0.2 -0.3 0.6 0.3 0.1 0.3 -0.2 0.6 0.1 0.1 -0.6 -1 -0.4
0019 0.3 0.9 0.2 0.8 0.3 0.3 -0.7 -0.5 0 -0.3 0.1 -0.2 -0.6 -0.1 0.2 0.2 -0.2 -0.2 -0.5 -0.2
0020 0.4 -0.7 -1.1 -1 -0.6 -0.6 -1.2 -1.2 1.5 1.6 1.2 0.1 -0.4 1 0.8 0.6 -0.8 1.7 -0.3 -0.8
0021 0.6 -0.7 2.1 1.8 2.7 -0.4 -1.5 -1 0.2 0.1 0.6 -0.2 -0.9 -0.4 -0.9 -1.1 0.2 -0.8 -1.2 0.2
0022 1.2 -1.4 -1 -0.9 -0.8 -1.2 -1.4 -0.9 2.8 2.1 0.8 -0.9 -0.6 0.8 -0.1 1 0.1 0.1 1.2 -1.4
0023 1.3 -0.4 -0.4 0.5 0.4 -0.7 -1.4 -0.9 0.8 1.3 0.6 -0.1 -1.2 -0.5 0.4 0.6 0 -0.1 1.5 -1.2
0024 0.7 -0.8 -0.2 0.3 0.2 -0.6 -1.2 -1 1.2 1.4 0.7 -0.1 -0.9 0.1 0.3 0.7 0.4 0.2 -0.7 -1.1
0025 0.7 -1 -0.6 -0.2 0 -0.6 -0.9 -0.9 0.9 1.3 0.9 0.1 -1 0.3 0.9 0.4 0.6 -0.1 0 -1
0026 0.6 0.1 1.8 2.1 2 0.7 -0.6 -0.6 -0.4 -0.1 -0.6 -0.6 -0.6 -0.6 -0.6 -0.6 -0.4 -0.6 -0.3 -0.3
0027 0.3 -0.9 -0.8 0.1 0.2 -0.7 -1.1 -1.1 0.6 0.6 0.3 -0.2 -0.2 0.9 0.8 1.3 2.3 0.1 -1.1 -0.8
0028 0.8 -0.7 -0.1 0.6 -0.2 -0.6 -0.9 -0.6 1.3 1.2 -0.1 -0.8 -0.8 0.3 -0.4 0.3 -0.1 0.7 1.8 -0.9
0029 0.7 -1.1 -1.1 -0.8 -1 -0.9 -1.1 -1.1 2.7 2.2 0.3 -0.8 -0.1 1.2 0.3 1.5 1.6 0.7 -0.9 -1.1
0030 1.3 -0.6 -0.4 0.1 0 0 -0.7 -0.7 0.3 -0.4 0.3 -0.4 -0.4 0 0.1 1.9 1.8 -0.4 -0.5 -0.7
0031 0 -0.8 -0.5 0.6 -0.4 -0.8 -0.9 -0.8 1.1 0.3 1.1 -0.4 0.8 0.9 -0.3 0.6 1.6 -0.1 -0.4 -0.6
0032 0.5 2.4 1 2 0.1 0.2 -0.6 0.2 -0.6 -0.6 -0.3 -0.5 -0.6 -0.6 -0.6 0.1 -0.6 -0.4 -0.6 -0.6
0033 0.9 0.6 0.7 0.1 1.2 0.4 -1.4 -0.6 -0.7 -0.4 0.7 0.1 -0.6 -0.5 0.5 0.3 1.2 -0.6 -1.4 -1.4
0034 0.4 -1 -1.3 -1.1 -0.6 -1.3 -1.3 -1.3 2.5 2.6 1.9 0 -1 1.3 0.9 0.6 0.3 0.1 -1.3 -1.1
- A F I L V M W Y D E K R H N Q S T G P C
0035 0.2 -0.9 0 -0.9 -0.2 -0.9 -0.9 -0.9 4.4 2.1 -0.5 -0.5 -0.5 0.5 -0.4 0.5 0.9 0.1 -0.9 -0.9
0036 0 0.9 1.2 5.5 0.3 0 -0.9 0.3 -0.4 0.4 -0.9 -0.9 0.4 -0.9 -0.9 -0.6 -0.9 -0.9 -0.9 -0.6
0037 0.3 -0.9 -1.2 -0.7 -1.2 -0.9 -1.2 -0.5 2.8 2.2 0.9 -0.8 -0.4 1.5 0.6 0.3 -1.2 3.4 -1.2 -0.8
0038 -0.4 0.3 2 1.9 1.1 0.2 -0.1 -0.3 -0.5 -0.3 -0.5 -0.5 -0.5 -0.5 -0.5 -0.1 -0.3 0 -0.3 -0.2
0039 -0.4 -0.4 -0.4 -0.4 -0.4 -0.4 -0.4 -0.4 2.9 0.3 -0.4 -0.4 -0.1 1.9 -0.4 0.5 0.4 -0.4 -0.4 -0.4
0040 -0.5 0.2 -0.5 -0.5 -0.5 -0.2 -0.5 0.4 -0.2 -0.5 -0.5 -0.5 -0.5 -0.2 -0.5 6.4 -0.2 -0.5 -0.2 -0.5
0041 0.8 0.4 1.2 1.1 1 0.7 -0.5 0 -0.5 -0.2 -0.5 -0.3 -0.5 -0.5 -0.3 -0.3 0.4 -0.5 -0.5 -0.5
0042 0.8 -0.7 -0.7 -0.4 -0.7 0 -0.7 -0.4 0.8 1.3 0.2 0.5 0 0.6 -0.5 0.6 0.5 0 -0.4 -0.7
0043 0.6 0.9 1.4 2 1.4 0 -0.8 0 -0.8 -0.7 0.1 -0.4 0.1 -0.7 -0.1 0.1 -0.1 -0.6 -0.8 -0.8
0044 1 0.8 1.4 1.1 -0.1 1.2 -0.3 0.5 -0.5 -0.4 -0.5 -0.5 -0.5 -0.5 -0.5 -0.5 0.1 -0.5 -0.1 -0.5
0045 0 -0.3 -0.2 -0.1 -0.1 -0.2 -0.6 -0.4 1.4 0.9 -0.6 0 -0.6 0.3 0.8 0.6 0.7 -0.2 -0.6 -0.6
0046 -0.1 0.8 1.6 1.6 1.1 1.2 -0.5 0.2 -0.5 -0.5 -0.5 -0.5 -0.5 -0.5 -0.5 -0.3 -0.5 -0.2 -0.5 -0.5
0047 1 -0.1 2 2.2 2.4 1.2 -0.9 -0.9 -0.6 -0.6 -0.9 -0.5 -0.6 -0.5 -0.9 0.1 0.4 -0.4 -0.9 -0.5
0048 0.3 0.3 1.1 1 0.9 1.4 -0.9 0 0.4 -0.5 -0.9 -0.9 -0.5 -0.3 -0.4 0.6 0.5 0.3 -0.9 -0.7
0049 1.4 -1 -0.1 0.4 0.2 -0.3 -0.8 -0.5 0.9 1.5 0.4 0.3 0 -0.1 0.5 -0.1 0.3 0 -1 -1
0050 0.4 0.6 2.6 2.8 2.2 1.1 -0.8 -0.8 -0.8 -0.8 -0.8 -0.8 -0.8 -0.8 -0.8 -0.4 -0.3 -0.8 -0.8 0
0051 -0.1 -0.8 -0.8 -0.8 -0.8 -0.8 -0.8 -0.8 0.7 4.6 1.4 0.8 -0.8 0.1 1.6 0.3 -0.8 -0.2 -0.8 -0.4
0052 -0.1 -0.9 -0.8 -1 -0.7 -1 -1.2 -0.7 2.4 2.5 1.5 0.8 -0.3 0.6 0.7 0.7 0.1 -0.3 -0.1 -1.2
0053 1.3 -0.6 -0.2 0.3 0 -0.1 -1.2 -0.7 -0.3 2.1 1.7 0.6 0 0.3 0.5 -0.2 0.6 -0.9 -1.4 -1.3
0054 -0.5 2.9 0.2 1.8 -0.1 0.5 -0.4 1.4 -0.8 -0.8 -0.8 -0.8 -0.6 -0.8 -0.8 -0.3 1.7 -0.8 -0.8 -0.7
0055 0.5 -1.2 -0.9 -1.2 -0.5 -1.2 -1.2 -1.2 2.1 1.1 1.2 -0.6 -0.4 1.5 -0.4 0.9 -0.7 3.6 -0.9 -1.2
0056 -0.2 -0.2 1.7 1.2 1.6 0.7 -0.8 -0.5 -0.5 -0.4 0 0.5 -0.5 -0.6 -0.3 -0.4 0.4 -0.3 -0.8 -0.2
0057 0.2 -1.4 -0.9 -1.1 0.4 -0.8 -1.4 -1.2 0.9 2.3 2.1 1.6 -0.8 0.3 1.2 1.2 1.4 -1 -0.4 -1.4
0058 -0.4 1.7 2.1 2.5 1.8 0.5 -0.4 -0.4 -0.6 -0.6 -0.6 -0.6 -0.4 -0.6 -0.6 -0.6 -0.6 -0.6 -0.4 -0.4
0059 0.4 -0.7 -0.7 -0.5 -0.6 -0.5 -0.9 -0.9 1.4 1.1 0.2 -0.2 -0.9 0.2 0 1.5 0.5 0 1.2 -0.7
0060 0.9 -0.3 -0.8 -0.2 0.1 -0.1 -0.6 -0.6 0.9 1.7 -0.4 -0.7 -0.7 0.1 0.4 0 0.4 0.1 0.7 -0.8
0061 0.9 -1.3 -0.4 -1.2 -0.5 -0.8 -1.3 -1.3 3 3.5 1 -0.3 -0.8 0.4 0.1 1.3 0.7 0.1 -1.1 -1.3
0062 0.7 -1 0.2 -0.4 0.8 -0.8 -1 -0.5 1.7 2 0.1 -0.1 -0.5 -0.2 0.8 0.5 0.2 -0.2 -1 -1
0063 1.7 1.4 0.9 1.9 1.1 0.3 -0.8 -0.1 -0.7 -0.4 -0.7 -0.6 -0.7 -0.9 -0.3 0 0.1 -0.7 -0.9 -0.9
0064 0.7 -0.7 -0.4 0.4 -0.1 -0.9 -1 -1.2 1.1 1.7 1.1 0.6 -1.1 0 0.7 0.2 0.2 0 0 -1.4
- A F I L V M W Y D E K R H N Q S T G P C
0065 1 -1.3 -1.2 -0.8 -1.2 -1.3 -1.3 -0.9 1.2 1.5 1.7 0.1 0.5 1.2 1.1 1.4 0.9 0.8 -0.9 -1.3
0066 0.4 0.8 1.8 1.7 1.7 1.2 -0.3 -0.3 -0.8 -0.4 -0.6 -0.6 -0.6 -0.8 -0.8 -0.3 0 -0.8 -0.6 -0.1
0067 0.2 -0.7 -0.3 0.6 0.8 -0.6 -1.1 -1 0.1 0.8 1.3 0.9 0 0 0.8 0.3 1.3 -0.8 -0.3 -1.2
0068 -0.4 -0.5 -0.6 -0.6 -0.1 -0.8 -0.8 -0.8 0.2 -0.8 1 0.1 -0.5 1.7 -0.8 2.3 2.5 -0.1 -0.8 0.6
0069 0.1 0.5 1.6 1.7 1.6 0.8 -0.6 -0.5 -0.6 -0.6 -0.6 -0.6 -0.6 -0.5 -0.6 -0.4 -0.2 -0.5 0.6 0.1
0070 1.4 -0.9 -0.9 -0.7 -0.8 -0.9 -0.9 -0.9 0.9 1.2 1 0.2 -0.4 0.6 0.8 1 -0.3 2 -0.3 -0.9
0071 1.2 -0.8 -0.9 -0.4 -0.9 -0.8 -1 -1 3.6 2 0.4 -0.5 -0.3 0.5 1.4 0.8 0.1 0.1 -1 -1
0072 0.6 0.6 1.4 1.8 1.2 1 -0.6 -0.5 -0.6 -0.6 -0.6 -0.6 -0.6 -0.5 -0.6 -0.1 0.2 -0.4 -0.6 -0.1
0073 1.2 0.5 1.1 1.1 1 0.1 -0.6 0.3 -0.5 0 -0.2 -0.8 -0.3 -0.7 -0.4 -0.1 0.3 -0.6 -0.8 0.3
0074 0.9 -0.9 -0.9 -0.4 -0.2 -1 -1 -0.9 2.4 2 0.4 -0.1 -0.6 0.9 0.7 0.6 0.7 0 -0.9 -0.8
0075 1.1 1 0.3 1.6 0.5 0.1 -0.6 0.8 -0.8 -0.3 -0.4 -0.6 0 -0.7 0 -0.3 0.2 -0.4 -0.9 -0.4
0076 0.2 0.1 2.6 2.2 2.2 0.2 -0.6 -0.5 -0.6 -0.6 -0.6 -0.6 -0.6 -0.6 -0.6 -0.6 -0.2 -0.6 -0.6 -0.6
0077 0.8 -1.3 -0.2 0.2 -0.3 -0.5 -1.4 -0.5 1 2.1 1.1 0.5 -0.8 0.5 1 0.6 0.3 -0.6 -1.5 -0.8
0078 1.3 -1.3 -1.1 -0.5 -1 -1.3 -1.3 -1.3 0.9 1.8 1.7 0.3 -0.3 1.2 0.6 1.4 0.4 0.5 -1 -1.3
0079 1.5 -1 0 1.7 0.1 -0.4 -1.2 -0.1 -1.1 0.2 1.4 0.8 0.6 0.3 0.5 -0.4 -0.5 -0.5 -1.1 -1.1
0080 0.5 -1 0.7 1.3 0.6 -0.1 -1.1 -0.7 -0.8 -0.3 1 -0.1 -0.7 -0.4 0.5 0.2 0.1 -0.1 -0.7 -0.7
Select residue pair below:
i_j Score Prob
0010_0053 3.966 1.00
0070_0074 3.433 1.00
0031_0034 3.046 1.00
0007_0077 2.547 1.00
0032_0072 2.382 1.00
0067_0071 2.227 1.00
0028_0070 2.098 1.00
0016_0023 1.906 1.00
0008_0012 1.814 1.00
0071_0074 1.753 1.00
0011_0050 1.749 1.00
0008_0028 1.743 1.00
0066_0072 1.682 1.00
0008_0073 1.655 1.00
0013_0023 1.582 1.00
0012_0023 1.462 1.00
0027_0030 1.461 1.00
0016_0026 1.425 1.00
0019_0038 1.425 1.00
0029_0070 1.425 1.00
0044_0048 1.424 1.00
0022_0025 1.397 0.99
0062_0079 1.333 0.99
0049_0052 1.325 0.99
0062_0075 1.274 0.99
0026_0030 1.270 0.99
0044_0060 1.263 0.99
0074_0077 1.248 0.99
0009_0013 1.171 0.98
0011_0073 1.113 0.96
0012_0016 1.078 0.95
0032_0043 1.068 0.95
0010_0054 1.068 0.95
0026_0069 1.038 0.94
0038_0048 1.023 0.93
0058_0075 1.009 0.93
0019_0046 0.998 0.92
0059_0062 0.986 0.92
0074_0078 0.977 0.91
0028_0073 0.958 0.90
0032_0045 0.918 0.87
0018_0049 0.915 0.87
0046_0050 0.913 0.87
0016_0030 0.913 0.87
0005_0009 0.898 0.86
0038_0051 0.884 0.84
0011_0076 0.881 0.84
0038_0042 0.871 0.83
0075_0079 0.870 0.83
0063_0072 0.860 0.82
0047_0063 0.856 0.82
0028_0074 0.855 0.82
0039_0042 0.853 0.81
0013_0053 0.851 0.81
0033_0067 0.835 0.80
0043_0066 0.830 0.79
0052_0057 0.803 0.76
0066_0075 0.794 0.75
0069_0073 0.792 0.74
0019_0030 0.757 0.69
0059_0075 0.755 0.69
0007_0073 0.751 0.69
0062_0065 0.740 0.67
0010_0013 0.736 0.66
0017_0076 0.723 0.64
0031_0068 0.720 0.64
0054_0060 0.708 0.62
0031_0067 0.700 0.61
0006_0009 0.699 0.60
0060_0072 0.691 0.59
0041_0046 0.683 0.58
0015_0069 0.671 0.56
0018_0038 0.669 0.55
0012_0026 0.660 0.54
0076_0080 0.648 0.52
0020_0048 0.643 0.51
0012_0019 0.638 0.50
0044_0064 0.630 0.49
0015_0038 0.628 0.48
0050_0072 0.627 0.48
0046_0072 0.619 0.47
0017_0025 0.617 0.47
0012_0073 0.606 0.45
0049_0059 0.593 0.42
0018_0030 0.590 0.42
0043_0063 0.580 0.40
0011_0043 0.580 0.40
0045_0049 0.577 0.40
0021_0024 0.575 0.39
0038_0049 0.571 0.39
0056_0076 0.570 0.39
0058_0066 0.569 0.39
0033_0071 0.565 0.38
0015_0019 0.563 0.38
0041_0056 0.560 0.37
0015_0032 0.557 0.37
0007_0076 0.556 0.36
0044_0047 0.551 0.36
0009_0016 0.549 0.35
0007_0080 0.548 0.35
0007_0011 0.548 0.35
0031_0035 0.541 0.34
0045_0063 0.540 0.34
0014_0046 0.538 0.34
0025_0030 0.532 0.33
0015_0026 0.531 0.33
0011_0080 0.529 0.32
0011_0014 0.518 0.31
0055_0059 0.516 0.30
0039_0045 0.513 0.30
0042_0047 0.513 0.30
0010_0058 0.512 0.30
0037_0048 0.509 0.29
Local Interactions:
i_j Score Prob
0022_0024 2.116 1.00
0027_0029 1.827 1.00
0028_0029 1.588 1.00
0078_0079 1.557 1.00
0044_0045 1.196 0.98
0024_0025 1.177 0.98
0033_0034 1.102 0.96
0079_0080 1.092 0.96
0025_0027 0.898 0.86
0023_0024 0.861 0.82
0065_0067 0.858 0.82
0008_0009 0.857 0.82
0018_0019 0.853 0.81
0005_0006 0.835 0.80
0077_0078 0.816 0.77
0064_0065 0.812 0.77
0027_0028 0.774 0.72
0068_0070 0.773 0.72
0019_0020 0.760 0.70
0061_0062 0.755 0.69
0044_0046 0.754 0.69
0055_0056 0.739 0.67
0058_0059 0.727 0.65
0039_0041 0.706 0.62
0018_0020 0.692 0.59
0028_0030 0.657 0.53
0068_0069 0.619 0.47
0043_0044 0.595 0.43
0078_0080 0.570 0.39
0058_0060 0.559 0.37
0041_0042 0.532 0.33
0054_0056 0.509 0.29
See all coupling residues
Download raw data
Renumber residues to start with:
Position: 1 2 3 4 5 ...
Sequence: M S T T D ...
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