| catks1 |
| ID: | 1499455966 |
Query Sequence |
Download Alignment We filter this alignment to remove positions that have > 75% gaps before running GREMLIN. |
| Length: | 940 (877) | ||
| Sequences: | 12733 (10823.5) | ||
| Seq/Len: | 14.519 | ||
| Nf(neff/√len): | 365.5 |
HHblits Results: (2016_02)
Sequences per length for each position, BEFORE the coverage/gap filter was applied
Legend: Dots above the red line, indicates positions where there is > 5 sequences per length (if visible, green bar = 20 seq/len). Point of this graphic is to give you an idea if resubmitting a sub-portion of your sequence might help increase the overall Seq/Len (which after applying the coverage filter is at: 14.519).
Sequences per length for each position, AFTER the coverage/gap filter was applied
Residue pairs sorted by coevolution strength:
Legend: The darker and larger the blue dots, the higher strength in covariance. Below we provide the list of the top [1.5 x length] covarying residues with sequence seperation > 3. The i and j are positions as given in the input sequence.
| i | j | Scaled score | Prob |
| 638_L | 655_M | 4.731 | 1.00 |
| 835_I | 874_G | 3.948 | 1.00 |
| 540_V | 565_L | 3.857 | 1.00 |
| 538_Q | 637_D | 3.463 | 1.00 |
| 538_Q | 844_R | 3.280 | 1.00 |
| 567_I | 576_Q | 3.280 | 1.00 |
| 308_D | 336_R | 3.260 | 1.00 |
| 657_P | 844_R | 3.206 | 1.00 |
| 582_D | 643_Y | 2.993 | 1.00 |
| 102_L | 118_S | 2.842 | 1.00 |
| 875_R | 883_Q | 2.769 | 1.00 |
| 520_D | 559_K | 2.707 | 1.00 |
| 679_R | 704_T | 2.619 | 1.00 |
| 524_N | 559_K | 2.612 | 1.00 |
| 493_S | 520_D | 2.531 | 1.00 |
| 542_A | 585_A | 2.512 | 1.00 |
| 345_L | 353_D | 2.506 | 1.00 |
| 818_I | 874_G | 2.499 | 1.00 |
| 788_I | 816_V | 2.499 | 1.00 |
| 832_I | 885_L | 2.486 | 1.00 |
| 280_S | 290_V | 2.471 | 1.00 |
| 71_T | 169_S | 2.454 | 1.00 |
| 529_Y | 533_L | 2.447 | 1.00 |
| 838_S | 867_I | 2.398 | 1.00 |
| 495_Q | 499_S | 2.394 | 1.00 |
| 298_L | 448_L | 2.392 | 1.00 |
| 517_G | 521_R | 2.351 | 1.00 |
| 526_I | 552_E | 2.350 | 1.00 |
| 657_P | 660_G | 2.340 | 1.00 |
| 535_V | 562_C | 2.339 | 1.00 |
| 347_F | 452_V | 2.335 | 1.00 |
| 820_D | 836_C | 2.311 | 1.00 |
| 520_D | 628_S | 2.294 | 1.00 |
| 660_G | 784_T | 2.287 | 1.00 |
| 849_R | 852_L | 2.264 | 1.00 |
| 816_V | 837_L | 2.242 | 1.00 |
| 773_R | 793_P | 2.227 | 1.00 |
| 237_Q | 357_N | 2.223 | 1.00 |
| 495_Q | 498_L | 2.217 | 1.00 |
| 426_M | 438_M | 2.212 | 1.00 |
| 537_E | 637_D | 2.208 | 1.00 |
| 524_N | 528_H | 2.206 | 1.00 |
| 526_I | 556_G | 2.200 | 1.00 |
| 435_A | 439_S | 2.200 | 1.00 |
| 721_D | 725_K | 2.199 | 1.00 |
| 539_S | 586_S | 2.175 | 1.00 |
| 90_R | 94_R | 2.174 | 1.00 |
| 535_V | 539_S | 2.168 | 1.00 |
| 230_H | 364_G | 2.142 | 1.00 |
| 818_I | 882_V | 2.136 | 1.00 |
| 283_Y | 348_S | 2.122 | 1.00 |
| 486_G | 494_E | 2.110 | 1.00 |
| 92_L | 196_F | 2.110 | 1.00 |
| 251_Y | 434_S | 2.107 | 1.00 |
| 539_S | 562_C | 2.081 | 1.00 |
| 540_V | 641_V | 2.074 | 1.00 |
| 815_G | 860_H | 2.045 | 1.00 |
| 894_V | 922_F | 2.039 | 1.00 |
| 550_V | 686_F | 2.032 | 1.00 |
| 296_G | 337_I | 2.022 | 1.00 |
| 153_P | 180_A | 2.012 | 1.00 |
| 95_R | 192_E | 2.008 | 1.00 |
| 638_L | 844_R | 1.988 | 1.00 |
| 678_S | 729_N | 1.987 | 1.00 |
| 499_S | 502_S | 1.986 | 1.00 |
| 663_N | 813_N | 1.978 | 1.00 |
| 303_S | 444_I | 1.970 | 1.00 |
| 641_V | 847_I | 1.969 | 1.00 |
| 736_S | 758_E | 1.939 | 1.00 |
| 176_G | 181_L | 1.938 | 1.00 |
| 578_Y | 650_K | 1.936 | 1.00 |
| 709_E | 712_E | 1.932 | 1.00 |
| 503_L | 513_S | 1.919 | 1.00 |
| 310_N | 334_P | 1.914 | 1.00 |
| 426_M | 442_K | 1.903 | 1.00 |
| 732_A | 786_F | 1.900 | 1.00 |
| 892_V | 901_L | 1.894 | 1.00 |
| 815_G | 838_S | 1.883 | 1.00 |
| 92_L | 193_F | 1.855 | 1.00 |
| 877_L | 883_Q | 1.845 | 1.00 |
| 523_S | 559_K | 1.836 | 1.00 |
| 860_H | 865_Y | 1.817 | 1.00 |
| 832_I | 873_R | 1.802 | 1.00 |
| 276_L | 287_W | 1.788 | 1.00 |
| 543_I | 553_W | 1.767 | 1.00 |
| 520_D | 524_N | 1.763 | 1.00 |
| 580_L | 585_A | 1.760 | 1.00 |
| 348_S | 457_D | 1.756 | 1.00 |
| 706_C | 728_I | 1.753 | 1.00 |
| 536_A | 539_S | 1.752 | 1.00 |
| 679_R | 728_I | 1.738 | 1.00 |
| 678_S | 703_A | 1.725 | 1.00 |
| 231_E | 367_Y | 1.724 | 1.00 |
| 514_I | 552_E | 1.711 | 1.00 |
| 415_F | 424_L | 1.711 | 1.00 |
| 834_E | 869_R | 1.709 | 1.00 |
| 522_R | 549_E | 1.707 | 1.00 |
| 86_F | 90_R | 1.706 | 1.00 |
| 877_L | 881_N | 1.702 | 1.00 |
| 506_Y | 704_T | 1.701 | 1.00 |
| 540_V | 563_V | 1.700 | 1.00 |
| 678_S | 751_K | 1.700 | 1.00 |
| 102_L | 151_E | 1.699 | 1.00 |
| 636_T | 659_Q | 1.696 | 1.00 |
| 487_R | 490_R | 1.692 | 1.00 |
| 501_Q | 517_G | 1.691 | 1.00 |
| 451_T | 464_P | 1.688 | 1.00 |
| 670_N | 812_E | 1.682 | 1.00 |
| 660_G | 842_M | 1.680 | 1.00 |
| 459_D | 462_Q | 1.672 | 1.00 |
| 556_G | 560_A | 1.667 | 1.00 |
| 777_N | 786_F | 1.666 | 1.00 |
| 636_T | 657_P | 1.660 | 1.00 |
| 690_V | 732_A | 1.656 | 1.00 |
| 308_D | 338_P | 1.652 | 1.00 |
| 507_S | 548_M | 1.647 | 1.00 |
| 693_L | 786_F | 1.646 | 1.00 |
| 295_I | 387_V | 1.641 | 1.00 |
| 413_F | 426_M | 1.639 | 1.00 |
| 191_R | 324_D | 1.631 | 1.00 |
| 189_L | 326_M | 1.625 | 1.00 |
| 162_P | 168_R | 1.622 | 1.00 |
| 712_E | 718_Y | 1.621 | 1.00 |
| 816_V | 835_I | 1.619 | 1.00 |
| 715_I | 718_Y | 1.610 | 1.00 |
| 455_Y | 458_F | 1.609 | 1.00 |
| 684_S | 690_V | 1.607 | 1.00 |
| 578_Y | 643_Y | 1.605 | 1.00 |
| 528_H | 629_P | 1.602 | 1.00 |
| 634_L | 637_D | 1.602 | 1.00 |
| 488_V | 661_L | 1.592 | 1.00 |
| 91_S | 94_R | 1.590 | 1.00 |
| 858_V | 867_I | 1.585 | 1.00 |
| 89_I | 156_F | 1.581 | 1.00 |
| 571_Y | 579_M | 1.577 | 1.00 |
| 96_H | 192_E | 1.574 | 1.00 |
| 821_P | 825_A | 1.572 | 1.00 |
| 73_D | 169_S | 1.569 | 1.00 |
| 312_Y | 385_E | 1.569 | 1.00 |
| 694_D | 732_A | 1.569 | 1.00 |
| 708_A | 722_V | 1.567 | 1.00 |
| 271_I | 424_L | 1.566 | 1.00 |
| 543_I | 554_I | 1.565 | 1.00 |
| 706_C | 722_V | 1.561 | 1.00 |
| 494_E | 498_L | 1.555 | 1.00 |
| 493_S | 559_K | 1.554 | 1.00 |
| 294_L | 449_F | 1.550 | 1.00 |
| 372_L | 376_A | 1.548 | 1.00 |
| 520_D | 523_S | 1.547 | 1.00 |
| 710_Y | 713_I | 1.537 | 1.00 |
| 693_L | 732_A | 1.535 | 1.00 |
| 664_F | 786_F | 1.531 | 1.00 |
| 816_V | 874_G | 1.530 | 1.00 |
| 506_Y | 726_N | 1.525 | 1.00 |
| 56_K | 105_D | 1.521 | 1.00 |
| 346_L | 349_D | 1.519 | 1.00 |
| 732_A | 735_P | 1.515 | 1.00 |
| 824_L | 836_C | 1.513 | 1.00 |
| 591_D | 594_D | 1.511 | 1.00 |
| 444_I | 470_Q | 1.506 | 1.00 |
| 683_F | 734_T | 1.504 | 1.00 |
| 722_V | 726_N | 1.504 | 1.00 |
| 493_S | 523_S | 1.495 | 1.00 |
| 85_I | 193_F | 1.493 | 1.00 |
| 553_W | 589_V | 1.492 | 1.00 |
| 369_Y | 373_A | 1.489 | 1.00 |
| 535_V | 541_V | 1.488 | 1.00 |
| 44_M | 113_F | 1.487 | 1.00 |
| 732_A | 777_N | 1.486 | 1.00 |
| 295_I | 413_F | 1.483 | 1.00 |
| 503_L | 704_T | 1.481 | 1.00 |
| 91_S | 200_D | 1.473 | 1.00 |
| 553_W | 557_V | 1.469 | 1.00 |
| 679_R | 706_C | 1.461 | 1.00 |
| 544_M | 553_W | 1.461 | 1.00 |
| 147_K | 150_K | 1.459 | 1.00 |
| 289_R | 355_S | 1.457 | 1.00 |
| 577_L | 581_Q | 1.456 | 1.00 |
| 573_N | 577_L | 1.453 | 1.00 |
| 514_I | 548_M | 1.452 | 1.00 |
| 133_L | 136_Q | 1.450 | 1.00 |
| 278_N | 282_K | 1.449 | 1.00 |
| 909_A | 917_L | 1.448 | 1.00 |
| 551_I | 695_W | 1.448 | 1.00 |
| 296_G | 311_L | 1.442 | 1.00 |
| 267_L | 430_P | 1.438 | 1.00 |
| 334_P | 372_L | 1.435 | 1.00 |
| 792_E | 806_L | 1.435 | 1.00 |
| 664_F | 693_L | 1.433 | 1.00 |
| 491_W | 662_S | 1.428 | 1.00 |
| 852_L | 856_K | 1.427 | 1.00 |
| 754_G | 777_N | 1.422 | 1.00 |
| 300_A | 339_I | 1.416 | 1.00 |
| 232_A | 236_S | 1.411 | 1.00 |
| 905_E | 920_V | 1.408 | 1.00 |
| 669_G | 701_S | 1.406 | 0.99 |
| 356_K | 360_V | 1.405 | 0.99 |
| 233_F | 361_A | 1.404 | 0.99 |
| 489_H | 658_H | 1.399 | 0.99 |
| 633_T | 637_D | 1.399 | 0.99 |
| 230_H | 366_V | 1.398 | 0.99 |
| 565_L | 583_S | 1.397 | 0.99 |
| 231_E | 375_R | 1.397 | 0.99 |
| 582_D | 849_R | 1.392 | 0.99 |
| 654_V | 843_A | 1.392 | 0.99 |
| 908_I | 931_A | 1.387 | 0.99 |
| 492_I | 496_A | 1.386 | 0.99 |
| 549_E | 591_D | 1.382 | 0.99 |
| 293_A | 350_L | 1.379 | 0.99 |
| 756_G | 786_F | 1.374 | 0.99 |
| 231_E | 235_I | 1.372 | 0.99 |
| 571_Y | 687_S | 1.370 | 0.99 |
| 277_K | 417_E | 1.369 | 0.99 |
| 582_D | 650_K | 1.369 | 0.99 |
| 681_L | 708_A | 1.367 | 0.99 |
| 269_M | 439_S | 1.366 | 0.99 |
| 787_T | 837_L | 1.364 | 0.99 |
| 371_D | 374_R | 1.364 | 0.99 |
| 446_I | 450_D | 1.363 | 0.99 |
| 294_L | 452_V | 1.361 | 0.99 |
| 850_T | 854_E | 1.351 | 0.99 |
| 338_P | 345_L | 1.350 | 0.99 |
| 241_T | 310_N | 1.348 | 0.99 |
| 103_F | 180_A | 1.348 | 0.99 |
| 85_I | 172_I | 1.348 | 0.99 |
| 563_V | 638_L | 1.331 | 0.99 |
| 337_I | 354_V | 1.331 | 0.99 |
| 732_A | 756_G | 1.331 | 0.99 |
| 665_V | 700_T | 1.324 | 0.99 |
| 503_L | 515_T | 1.324 | 0.99 |
| 439_S | 443_E | 1.323 | 0.99 |
| 464_P | 471_S | 1.318 | 0.99 |
| 84_R | 200_D | 1.317 | 0.99 |
| 228_A | 232_A | 1.314 | 0.99 |
| 235_I | 375_R | 1.313 | 0.99 |
| 811_L | 814_T | 1.311 | 0.99 |
| 503_L | 506_Y | 1.309 | 0.99 |
| 860_H | 867_I | 1.301 | 0.99 |
| 581_Q | 650_K | 1.299 | 0.99 |
| 297_V | 350_L | 1.299 | 0.99 |
| 492_I | 555_L | 1.298 | 0.99 |
| 690_V | 786_F | 1.297 | 0.99 |
| 250_P | 437_R | 1.297 | 0.99 |
| 590_L | 594_D | 1.292 | 0.99 |
| 792_E | 881_N | 1.287 | 0.99 |
| 486_G | 490_R | 1.287 | 0.99 |
| 873_R | 888_M | 1.285 | 0.99 |
| 915_V | 918_V | 1.279 | 0.99 |
| 339_I | 345_L | 1.279 | 0.99 |
| 689_D | 780_P | 1.275 | 0.99 |
| 836_C | 869_R | 1.275 | 0.99 |
| 141_L | 175_V | 1.272 | 0.99 |
| 761_S | 764_L | 1.271 | 0.99 |
| 783_F | 837_L | 1.271 | 0.99 |
| 367_Y | 375_R | 1.268 | 0.99 |
| 287_W | 422_V | 1.267 | 0.99 |
| 293_A | 354_V | 1.265 | 0.99 |
| 137_D | 159_S | 1.262 | 0.99 |
| 211_Y | 214_F | 1.262 | 0.99 |
| 690_V | 756_G | 1.261 | 0.99 |
| 656_L | 843_A | 1.261 | 0.99 |
| 505_L | 548_M | 1.255 | 0.99 |
| 681_L | 723_I | 1.253 | 0.99 |
| 817_D | 860_H | 1.250 | 0.99 |
| 682_Q | 707_F | 1.250 | 0.99 |
| 279_L | 453_A | 1.250 | 0.99 |
| 664_F | 785_V | 1.248 | 0.99 |
| 78_D | 158_I | 1.245 | 0.98 |
| 818_I | 835_I | 1.243 | 0.98 |
| 843_A | 857_F | 1.241 | 0.98 |
| 538_Q | 638_L | 1.240 | 0.98 |
| 76_Q | 170_T | 1.240 | 0.98 |
| 508_A | 709_E | 1.238 | 0.98 |
| 690_V | 693_L | 1.237 | 0.98 |
| 809_E | 881_N | 1.236 | 0.98 |
| 684_S | 732_A | 1.235 | 0.98 |
| 448_L | 463_F | 1.235 | 0.98 |
| 214_F | 217_F | 1.230 | 0.98 |
| 97_G | 210_N | 1.230 | 0.98 |
| 564_F | 692_I | 1.229 | 0.98 |
| 267_L | 435_A | 1.228 | 0.98 |
| 340_A | 345_L | 1.227 | 0.98 |
| 874_G | 884_I | 1.226 | 0.98 |
| 583_S | 643_Y | 1.225 | 0.98 |
| 489_H | 633_T | 1.225 | 0.98 |
| 491_W | 666_C | 1.221 | 0.98 |
| 675_D | 678_S | 1.220 | 0.98 |
| 303_S | 441_L | 1.218 | 0.98 |
| 752_S | 775_L | 1.218 | 0.98 |
| 664_F | 694_D | 1.218 | 0.98 |
| 698_A | 705_L | 1.217 | 0.98 |
| 440_E | 444_I | 1.215 | 0.98 |
| 196_F | 200_D | 1.212 | 0.98 |
| 91_S | 196_F | 1.208 | 0.98 |
| 829_T | 876_I | 1.208 | 0.98 |
| 693_L | 777_N | 1.205 | 0.98 |
| 760_C | 776_H | 1.203 | 0.98 |
| 664_F | 784_T | 1.196 | 0.98 |
| 141_L | 144_V | 1.196 | 0.98 |
| 505_L | 551_I | 1.195 | 0.98 |
| 924_L | 927_N | 1.190 | 0.98 |
| 542_A | 580_L | 1.188 | 0.98 |
| 515_T | 518_E | 1.186 | 0.98 |
| 298_L | 445_F | 1.185 | 0.98 |
| 109_T | 112_C | 1.185 | 0.98 |
| 664_F | 756_G | 1.182 | 0.98 |
| 428_Y | 438_M | 1.181 | 0.98 |
| 894_V | 899_V | 1.179 | 0.98 |
| 136_Q | 140_K | 1.178 | 0.98 |
| 492_I | 520_D | 1.178 | 0.98 |
| 756_G | 784_T | 1.176 | 0.98 |
| 909_A | 918_V | 1.174 | 0.98 |
| 77_R | 84_R | 1.171 | 0.98 |
| 664_F | 732_A | 1.168 | 0.97 |
| 51_L | 328_H | 1.167 | 0.97 |
| 297_V | 448_L | 1.166 | 0.97 |
| 902_G | 905_E | 1.164 | 0.97 |
| 828_P | 831_T | 1.163 | 0.97 |
| 661_L | 785_V | 1.162 | 0.97 |
| 783_F | 787_T | 1.156 | 0.97 |
| 340_A | 344_A | 1.156 | 0.97 |
| 698_A | 703_A | 1.155 | 0.97 |
| 434_S | 437_R | 1.155 | 0.97 |
| 283_Y | 352_R | 1.153 | 0.97 |
| 233_F | 237_Q | 1.153 | 0.97 |
| 141_L | 157_L | 1.150 | 0.97 |
| 458_F | 462_Q | 1.145 | 0.97 |
| 578_Y | 582_D | 1.144 | 0.97 |
| 237_Q | 360_V | 1.142 | 0.97 |
| 148_L | 179_I | 1.141 | 0.97 |
| 101_S | 117_F | 1.140 | 0.97 |
| 692_I | 785_V | 1.139 | 0.97 |
| 507_S | 510_L | 1.133 | 0.97 |
| 369_Y | 372_L | 1.133 | 0.97 |
| 674_L | 703_A | 1.132 | 0.97 |
| 292_T | 311_L | 1.131 | 0.97 |
| 523_S | 556_G | 1.129 | 0.97 |
| 732_A | 737_A | 1.128 | 0.97 |
| 730_F | 752_S | 1.127 | 0.97 |
| 683_F | 733_I | 1.127 | 0.97 |
| 817_D | 862_E | 1.127 | 0.97 |
| 783_F | 842_M | 1.126 | 0.97 |
| 656_L | 784_T | 1.122 | 0.97 |
| 739_A | 764_L | 1.121 | 0.97 |
| 655_M | 847_I | 1.120 | 0.96 |
| 101_S | 115_K | 1.120 | 0.96 |
| 285_T | 289_R | 1.119 | 0.96 |
| 275_T | 454_K | 1.119 | 0.96 |
| 383_L | 386_Q | 1.118 | 0.96 |
| 817_D | 838_S | 1.117 | 0.96 |
| 694_D | 786_F | 1.116 | 0.96 |
| 236_S | 239_Q | 1.116 | 0.96 |
| 912_C | 915_V | 1.115 | 0.96 |
| 890_R | 905_E | 1.114 | 0.96 |
| 452_V | 463_F | 1.113 | 0.96 |
| 678_S | 730_F | 1.113 | 0.96 |
| 694_D | 777_N | 1.113 | 0.96 |
| 433_F | 438_M | 1.112 | 0.96 |
| 158_I | 172_I | 1.109 | 0.96 |
| 156_F | 172_I | 1.109 | 0.96 |
| 535_V | 560_A | 1.109 | 0.96 |
| 533_L | 587_T | 1.109 | 0.96 |
| 493_S | 524_N | 1.108 | 0.96 |
| 47_P | 50_A | 1.104 | 0.96 |
| 103_F | 179_I | 1.104 | 0.96 |
| 506_Y | 513_S | 1.103 | 0.96 |
| 668_Y | 693_L | 1.101 | 0.96 |
| 496_A | 520_D | 1.099 | 0.96 |
| 261_N | 431_K | 1.095 | 0.96 |
| 762_E | 766_E | 1.093 | 0.96 |
| 477_P | 480_V | 1.088 | 0.96 |
| 755_L | 760_C | 1.088 | 0.96 |
| 275_T | 450_D | 1.088 | 0.96 |
| 573_N | 597_A | 1.086 | 0.96 |
| 566_V | 781_T | 1.085 | 0.96 |
| 462_Q | 825_A | 1.085 | 0.96 |
| 752_S | 773_R | 1.084 | 0.96 |
| 291_V | 422_V | 1.083 | 0.96 |
| 674_L | 678_S | 1.083 | 0.96 |
| 920_V | 931_A | 1.083 | 0.96 |
| 683_F | 786_F | 1.082 | 0.96 |
| 659_Q | 840_L | 1.081 | 0.95 |
| 545_K | 591_D | 1.078 | 0.95 |
| 558_L | 639_A | 1.076 | 0.95 |
| 837_L | 870_T | 1.074 | 0.95 |
| 683_F | 737_A | 1.074 | 0.95 |
| 108_K | 112_C | 1.074 | 0.95 |
| 413_F | 424_L | 1.072 | 0.95 |
| 49_E | 219_R | 1.070 | 0.95 |
| 358_L | 362_K | 1.068 | 0.95 |
| 344_A | 461_F | 1.065 | 0.95 |
| 372_L | 375_R | 1.064 | 0.95 |
| 574_E | 650_K | 1.063 | 0.95 |
| 727_Q | 749_S | 1.061 | 0.95 |
| 682_Q | 694_D | 1.060 | 0.95 |
| 738_L | 755_L | 1.060 | 0.95 |
| 191_R | 195_A | 1.059 | 0.95 |
| 233_F | 360_V | 1.059 | 0.95 |
| 271_I | 442_K | 1.059 | 0.95 |
| 681_L | 722_V | 1.058 | 0.95 |
| 733_I | 738_L | 1.055 | 0.95 |
| 76_Q | 85_I | 1.053 | 0.95 |
| 87_W | 200_D | 1.052 | 0.95 |
| 279_L | 283_Y | 1.052 | 0.95 |
| 554_I | 695_W | 1.051 | 0.94 |
| 71_T | 171_A | 1.051 | 0.94 |
| 836_C | 858_V | 1.050 | 0.94 |
| 669_G | 697_I | 1.050 | 0.94 |
| 542_A | 567_I | 1.048 | 0.94 |
| 624_N | 627_E | 1.048 | 0.94 |
| 664_F | 668_Y | 1.047 | 0.94 |
| 499_S | 517_G | 1.046 | 0.94 |
| 130_P | 163_D | 1.046 | 0.94 |
| 891_Q | 900_E | 1.046 | 0.94 |
| 691_S | 695_W | 1.045 | 0.94 |
| 664_F | 787_T | 1.045 | 0.94 |
| 276_L | 290_V | 1.043 | 0.94 |
| 821_P | 827_V | 1.043 | 0.94 |
| 876_I | 882_V | 1.043 | 0.94 |
| 529_Y | 532_S | 1.039 | 0.94 |
| 574_E | 578_Y | 1.038 | 0.94 |
| 522_R | 552_E | 1.036 | 0.94 |
| 489_H | 558_L | 1.032 | 0.94 |
| 811_L | 841_N | 1.030 | 0.94 |
| 98_I | 101_S | 1.028 | 0.94 |
| 443_E | 467_Q | 1.027 | 0.94 |
| 156_F | 174_I | 1.026 | 0.94 |
| 292_T | 296_G | 1.024 | 0.93 |
| 295_I | 389_I | 1.023 | 0.93 |
| 815_G | 865_Y | 1.022 | 0.93 |
| 289_R | 359_S | 1.021 | 0.93 |
| 522_R | 525_Q | 1.020 | 0.93 |
| 75_S | 168_R | 1.020 | 0.93 |
| 386_Q | 389_I | 1.019 | 0.93 |
| 907_V | 911_T | 1.018 | 0.93 |
| 387_V | 390_T | 1.017 | 0.93 |
| 390_T | 393_P | 1.015 | 0.93 |
| 640_Y | 656_L | 1.014 | 0.93 |
| 55_Y | 60_E | 1.013 | 0.93 |
| 548_M | 552_E | 1.011 | 0.93 |
| 349_D | 352_R | 1.010 | 0.93 |
| 490_R | 493_S | 1.010 | 0.93 |
| 285_T | 351_V | 1.009 | 0.93 |
| 683_F | 713_I | 1.008 | 0.93 |
| 703_A | 729_N | 1.007 | 0.93 |
| 45_S | 211_Y | 1.006 | 0.93 |
| 665_V | 697_I | 1.004 | 0.93 |
| 269_M | 442_K | 1.003 | 0.93 |
| 371_D | 375_R | 1.001 | 0.92 |
| 735_P | 738_L | 1.001 | 0.92 |
| 355_S | 359_S | 1.001 | 0.92 |
Prob = P(contact | scaled_score, seq/len).
Scaled Score = (raw_score/average(raw_scores)).
- Text file of contact predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
- Import to GREMLIN BETA - features includes ability to upload PDB and latest P(contact) calculation based on eLife 2015 fitting to PDB data.
GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled Score > 1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-position alignment confidence. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | M | Cov | P(%) | HHΔ | |
| 2vsqA | 1 | 0.9234 | 100 | 0.223 | Contact Map |
| 4dg8A | 1 | 0.4723 | 100 | 0.574 | Contact Map |
| 1amuA | 2 | 0.4819 | 100 | 0.59 | Contact Map |
| 4iz6A | 2 | 0.4872 | 100 | 0.598 | Contact Map |
| 3tsyA | 1 | 0.4351 | 100 | 0.599 | Contact Map |
| 4d4iA | 1 | 0 | 100 | 0.599 | Contact Map |
| 3wvnA | 2 | 0.4 | 100 | 0.608 | Contact Map |
| 4gr5A | 4 | 0.4819 | 100 | 0.61 | Contact Map |
| 3g7sA | 2 | 0.4713 | 100 | 0.61 | Contact Map |
| 4r0mB | 2 | 0.4798 | 100 | 0.613 | Contact Map |
Cov = coverage of hit
P(%) = probability
Sequence Conservation (Image Generated using WebLogo v3)