| TEB4 -force run |
| ID: | 1490020544 |
Query Sequence |
Download Alignment We filter this alignment to remove positions that have > 75% gaps before running GREMLIN. |
| Length: | 725 (718) | ||
| Sequences: | 162 (130.7) | ||
| Seq/Len: | 0.226 | ||
| Nf(neff/√len): | 4.9 |
HHblits Results: (2016_02)
Sequences per length for each position, BEFORE the coverage/gap filter was applied
Legend: Dots above the red line, indicates positions where there is > 5 sequences per length (if visible, green bar = 20 seq/len). Point of this graphic is to give you an idea if resubmitting a sub-portion of your sequence might help increase the overall Seq/Len (which after applying the coverage filter is at: 0.226).
Sequences per length for each position, AFTER the coverage/gap filter was applied
Residue pairs sorted by coevolution strength:
Legend: The darker and larger the blue dots, the higher strength in covariance. Below we provide the list of the top [1.5 x length] covarying residues with sequence seperation > 3. The i and j are positions as given in the input sequence.
| i | j | Scaled score | Prob |
| 449_E | 453_N | 2.349 | 0.81 |
| 577_L | 654_L | 1.996 | 0.65 |
| 19_V | 24_L | 1.905 | 0.59 |
| 82_V | 87_Q | 1.826 | 0.54 |
| 573_M | 654_L | 1.767 | 0.51 |
| 36_R | 86_E | 1.732 | 0.49 |
| 186_A | 402_V | 1.679 | 0.45 |
| 306_Y | 325_V | 1.623 | 0.42 |
| 19_V | 63_D | 1.592 | 0.40 |
| 502_V | 636_T | 1.494 | 0.34 |
| 628_D | 634_R | 1.488 | 0.34 |
| 231_I | 499_A | 1.487 | 0.34 |
| 193_L | 197_F | 1.476 | 0.33 |
| 279_T | 380_F | 1.464 | 0.33 |
| 405_L | 597_Q | 1.448 | 0.32 |
| 23_W | 339_P | 1.432 | 0.31 |
| 567_I | 644_A | 1.432 | 0.31 |
| 332_L | 362_F | 1.429 | 0.31 |
| 234_F | 557_L | 1.423 | 0.30 |
| 323_P | 348_V | 1.417 | 0.30 |
| 261_F | 398_G | 1.391 | 0.29 |
| 67_G | 228_G | 1.370 | 0.28 |
| 261_F | 441_L | 1.367 | 0.28 |
| 573_M | 579_V | 1.367 | 0.28 |
| 83_W | 163_L | 1.365 | 0.27 |
| 314_V | 325_V | 1.363 | 0.27 |
| 247_M | 366_I | 1.348 | 0.27 |
| 82_V | 86_E | 1.339 | 0.26 |
| 75_L | 193_L | 1.335 | 0.26 |
| 325_V | 718_Q | 1.335 | 0.26 |
| 460_L | 463_A | 1.331 | 0.26 |
| 15_I | 331_N | 1.328 | 0.26 |
| 337_F | 445_L | 1.318 | 0.25 |
| 691_L | 710_I | 1.314 | 0.25 |
| 18_L | 252_L | 1.312 | 0.25 |
| 268_W | 337_F | 1.310 | 0.25 |
| 575_F | 650_L | 1.309 | 0.25 |
| 279_T | 366_I | 1.294 | 0.24 |
| 2_L | 60_I | 1.294 | 0.24 |
| 253_L | 326_L | 1.293 | 0.24 |
| 19_V | 339_P | 1.277 | 0.23 |
| 386_P | 523_G | 1.276 | 0.23 |
| 257_E | 318_R | 1.276 | 0.23 |
| 123_L | 691_L | 1.270 | 0.23 |
| 19_V | 247_M | 1.269 | 0.23 |
| 519_P | 645_P | 1.264 | 0.23 |
| 67_G | 170_G | 1.263 | 0.23 |
| 617_P | 684_P | 1.263 | 0.23 |
| 84_L | 305_V | 1.262 | 0.23 |
| 321_L | 442_E | 1.261 | 0.23 |
| 342_E | 361_L | 1.261 | 0.23 |
| 294_T | 605_Q | 1.253 | 0.22 |
| 248_L | 255_L | 1.248 | 0.22 |
| 230_V | 696_L | 1.245 | 0.22 |
| 181_V | 549_C | 1.244 | 0.22 |
| 313_F | 361_L | 1.242 | 0.22 |
| 15_I | 403_E | 1.240 | 0.22 |
| 56_S | 518_V | 1.238 | 0.22 |
| 2_L | 604_L | 1.237 | 0.22 |
| 313_F | 358_S | 1.235 | 0.21 |
| 497_I | 663_I | 1.235 | 0.21 |
| 273_S | 327_W | 1.235 | 0.21 |
| 23_W | 173_G | 1.234 | 0.21 |
| 135_V | 522_L | 1.232 | 0.21 |
| 302_F | 544_I | 1.230 | 0.21 |
| 229_Y | 328_F | 1.226 | 0.21 |
| 60_I | 654_L | 1.226 | 0.21 |
| 445_L | 577_L | 1.224 | 0.21 |
| 173_G | 602_G | 1.224 | 0.21 |
| 247_M | 323_P | 1.221 | 0.21 |
| 682_S | 691_L | 1.220 | 0.21 |
| 418_T | 566_V | 1.220 | 0.21 |
| 304_M | 329_L | 1.218 | 0.21 |
| 515_F | 583_L | 1.215 | 0.21 |
| 86_E | 212_F | 1.213 | 0.21 |
| 576_Q | 627_R | 1.211 | 0.20 |
| 207_L | 330_R | 1.211 | 0.20 |
| 170_G | 228_G | 1.211 | 0.20 |
| 173_G | 519_P | 1.210 | 0.20 |
| 321_L | 406_V | 1.209 | 0.20 |
| 232_V | 340_I | 1.209 | 0.20 |
| 261_F | 396_P | 1.204 | 0.20 |
| 79_I | 168_L | 1.203 | 0.20 |
| 716_L | 721_L | 1.202 | 0.20 |
| 556_V | 577_L | 1.201 | 0.20 |
| 459_Q | 463_A | 1.200 | 0.20 |
| 173_G | 339_P | 1.198 | 0.20 |
| 327_W | 617_P | 1.198 | 0.20 |
| 73_I | 321_L | 1.197 | 0.20 |
| 85_R | 339_P | 1.196 | 0.20 |
| 278_A | 689_L | 1.195 | 0.20 |
| 561_L | 566_V | 1.191 | 0.20 |
| 168_L | 306_Y | 1.190 | 0.20 |
| 19_V | 23_W | 1.189 | 0.20 |
| 75_L | 188_N | 1.188 | 0.20 |
| 64_C | 577_L | 1.188 | 0.20 |
| 198_L | 555_S | 1.188 | 0.20 |
| 331_N | 362_F | 1.184 | 0.19 |
| 131_A | 134_I | 1.183 | 0.19 |
| 519_P | 602_G | 1.183 | 0.19 |
| 294_T | 604_L | 1.182 | 0.19 |
| 24_L | 63_D | 1.180 | 0.19 |
| 61_L | 349_A | 1.180 | 0.19 |
| 254_M | 338_N | 1.180 | 0.19 |
| 125_R | 678_I | 1.180 | 0.19 |
| 60_I | 536_V | 1.179 | 0.19 |
| 232_V | 640_E | 1.179 | 0.19 |
| 524_R | 657_P | 1.175 | 0.19 |
| 431_W | 680_R | 1.175 | 0.19 |
| 648_A | 689_L | 1.174 | 0.19 |
| 261_F | 308_F | 1.171 | 0.19 |
| 560_V | 642_L | 1.169 | 0.19 |
| 228_G | 524_R | 1.168 | 0.19 |
| 66_K | 268_W | 1.168 | 0.19 |
| 571_T | 609_F | 1.168 | 0.19 |
| 76_C | 80_S | 1.165 | 0.19 |
| 443_H | 447_P | 1.165 | 0.19 |
| 276_L | 373_P | 1.164 | 0.19 |
| 217_T | 464_D | 1.163 | 0.19 |
| 503_A | 699_Q | 1.162 | 0.19 |
| 281_L | 416_E | 1.161 | 0.19 |
| 78_F | 269_L | 1.158 | 0.18 |
| 356_I | 503_A | 1.157 | 0.18 |
| 218_Y | 222_P | 1.156 | 0.18 |
| 433_K | 626_N | 1.155 | 0.18 |
| 405_L | 547_Y | 1.154 | 0.18 |
| 122_D | 125_R | 1.153 | 0.18 |
| 283_R | 442_E | 1.153 | 0.18 |
| 442_E | 692_S | 1.152 | 0.18 |
| 522_L | 618_E | 1.151 | 0.18 |
| 306_Y | 326_L | 1.151 | 0.18 |
| 228_G | 386_P | 1.148 | 0.18 |
| 228_G | 523_G | 1.148 | 0.18 |
| 67_G | 524_R | 1.144 | 0.18 |
| 340_I | 537_H | 1.144 | 0.18 |
| 82_V | 638_L | 1.139 | 0.18 |
| 284_R | 299_H | 1.138 | 0.18 |
| 325_V | 715_Y | 1.138 | 0.18 |
| 307_V | 351_H | 1.137 | 0.18 |
| 281_L | 579_V | 1.136 | 0.18 |
| 329_L | 487_Y | 1.136 | 0.18 |
| 570_L | 649_S | 1.133 | 0.18 |
| 173_G | 645_P | 1.133 | 0.18 |
| 506_V | 532_G | 1.133 | 0.18 |
| 25_G | 192_T | 1.132 | 0.17 |
| 280_T | 648_A | 1.132 | 0.17 |
| 306_Y | 314_V | 1.131 | 0.17 |
| 353_R | 399_E | 1.130 | 0.17 |
| 412_P | 519_P | 1.129 | 0.17 |
| 71_V | 177_F | 1.128 | 0.17 |
| 566_V | 663_I | 1.128 | 0.17 |
| 387_F | 604_L | 1.127 | 0.17 |
| 339_P | 519_P | 1.126 | 0.17 |
| 406_V | 719_T | 1.125 | 0.17 |
| 2_L | 601_M | 1.124 | 0.17 |
| 549_C | 713_D | 1.123 | 0.17 |
| 409_I | 415_L | 1.122 | 0.17 |
| 175_L | 711_R | 1.122 | 0.17 |
| 385_L | 448_E | 1.121 | 0.17 |
| 406_V | 508_S | 1.121 | 0.17 |
| 268_W | 355_L | 1.120 | 0.17 |
| 572_G | 615_M | 1.119 | 0.17 |
| 198_L | 225_I | 1.119 | 0.17 |
| 358_S | 540_Y | 1.118 | 0.17 |
| 519_P | 524_R | 1.117 | 0.17 |
| 118_N | 123_L | 1.116 | 0.17 |
| 30_T | 348_V | 1.115 | 0.17 |
| 595_P | 662_G | 1.115 | 0.17 |
| 281_L | 701_T | 1.113 | 0.17 |
| 188_N | 382_P | 1.112 | 0.17 |
| 25_G | 195_F | 1.112 | 0.17 |
| 60_I | 688_F | 1.112 | 0.17 |
| 13_W | 252_L | 1.112 | 0.17 |
| 250_V | 326_L | 1.112 | 0.17 |
| 24_L | 645_P | 1.111 | 0.17 |
| 86_E | 197_F | 1.111 | 0.17 |
| 194_C | 612_L | 1.110 | 0.17 |
| 179_E | 354_R | 1.110 | 0.17 |
| 556_V | 688_F | 1.109 | 0.17 |
| 267_W | 574_C | 1.109 | 0.17 |
| 36_R | 628_D | 1.109 | 0.17 |
| 323_P | 443_H | 1.109 | 0.17 |
| 519_P | 599_W | 1.108 | 0.17 |
| 258_I | 712_N | 1.108 | 0.17 |
| 172_D | 356_I | 1.107 | 0.17 |
| 26_V | 497_I | 1.106 | 0.17 |
| 225_I | 442_E | 1.106 | 0.17 |
| 192_T | 563_V | 1.106 | 0.17 |
| 235_A | 648_A | 1.106 | 0.17 |
| 13_W | 171_L | 1.106 | 0.17 |
| 65_F | 647_L | 1.104 | 0.16 |
| 353_R | 629_G | 1.103 | 0.16 |
| 180_H | 432_C | 1.103 | 0.16 |
| 274_L | 348_V | 1.103 | 0.16 |
| 690_M | 694_Q | 1.102 | 0.16 |
| 575_F | 595_P | 1.101 | 0.16 |
| 292_P | 339_P | 1.100 | 0.16 |
| 296_V | 627_R | 1.099 | 0.16 |
| 368_L | 481_P | 1.098 | 0.16 |
| 354_R | 706_L | 1.098 | 0.16 |
| 497_I | 593_F | 1.097 | 0.16 |
| 259_G | 267_W | 1.097 | 0.16 |
| 74_F | 345_D | 1.097 | 0.16 |
| 181_V | 607_K | 1.097 | 0.16 |
| 233_S | 260_F | 1.096 | 0.16 |
| 565_V | 689_L | 1.096 | 0.16 |
| 307_V | 332_L | 1.096 | 0.16 |
| 87_Q | 336_D | 1.095 | 0.16 |
| 292_P | 412_P | 1.094 | 0.16 |
| 67_G | 386_P | 1.094 | 0.16 |
| 67_G | 523_G | 1.094 | 0.16 |
| 261_F | 338_N | 1.094 | 0.16 |
| 313_F | 399_E | 1.093 | 0.16 |
| 60_I | 704_K | 1.093 | 0.16 |
| 518_V | 688_F | 1.093 | 0.16 |
| 567_I | 647_L | 1.093 | 0.16 |
| 576_Q | 599_W | 1.092 | 0.16 |
| 175_L | 588_F | 1.091 | 0.16 |
| 506_V | 659_V | 1.090 | 0.16 |
| 173_G | 716_L | 1.090 | 0.16 |
| 133_R | 651_S | 1.089 | 0.16 |
| 234_F | 583_L | 1.088 | 0.16 |
| 509_V | 579_V | 1.088 | 0.16 |
| 194_C | 632_G | 1.088 | 0.16 |
| 366_I | 605_Q | 1.086 | 0.16 |
| 331_N | 403_E | 1.086 | 0.16 |
| 180_H | 599_W | 1.085 | 0.16 |
| 162_E | 321_L | 1.085 | 0.16 |
| 214_S | 623_I | 1.083 | 0.16 |
| 85_R | 412_P | 1.083 | 0.16 |
| 374_L | 432_C | 1.083 | 0.16 |
| 363_F | 374_L | 1.082 | 0.16 |
| 362_F | 538_E | 1.082 | 0.16 |
| 602_G | 645_P | 1.081 | 0.16 |
| 224_A | 406_V | 1.080 | 0.16 |
| 529_K | 548_V | 1.080 | 0.16 |
| 515_F | 659_V | 1.080 | 0.16 |
| 412_P | 524_R | 1.080 | 0.16 |
| 85_R | 292_P | 1.079 | 0.16 |
| 23_W | 524_R | 1.079 | 0.16 |
| 354_R | 500_I | 1.078 | 0.16 |
| 43_S | 503_A | 1.078 | 0.16 |
| 241_L | 687_L | 1.077 | 0.16 |
| 195_F | 245_Y | 1.077 | 0.16 |
| 292_P | 657_P | 1.076 | 0.16 |
| 18_L | 710_I | 1.076 | 0.16 |
| 59_N | 255_L | 1.075 | 0.16 |
| 625_F | 687_L | 1.075 | 0.16 |
| 225_I | 717_V | 1.074 | 0.15 |
| 121_E | 565_V | 1.074 | 0.15 |
| 34_I | 634_R | 1.073 | 0.15 |
| 305_V | 714_K | 1.072 | 0.15 |
| 7_I | 258_I | 1.071 | 0.15 |
| 6_E | 227_L | 1.071 | 0.15 |
| 438_L | 574_C | 1.071 | 0.15 |
| 28_P | 322_R | 1.071 | 0.15 |
| 259_G | 373_P | 1.070 | 0.15 |
| 412_P | 645_P | 1.070 | 0.15 |
| 307_V | 362_F | 1.068 | 0.15 |
| 402_V | 651_S | 1.068 | 0.15 |
| 202_L | 503_A | 1.068 | 0.15 |
| 151_D | 288_F | 1.066 | 0.15 |
| 23_W | 519_P | 1.066 | 0.15 |
| 94_Q | 366_I | 1.066 | 0.15 |
| 2_L | 683_Y | 1.066 | 0.15 |
| 507_T | 572_G | 1.065 | 0.15 |
| 300_W | 496_R | 1.064 | 0.15 |
| 162_E | 187_L | 1.063 | 0.15 |
| 577_L | 655_S | 1.063 | 0.15 |
| 52_F | 171_L | 1.063 | 0.15 |
| 563_V | 681_L | 1.062 | 0.15 |
| 339_P | 412_P | 1.062 | 0.15 |
| 178_L | 429_L | 1.061 | 0.15 |
| 563_V | 595_P | 1.060 | 0.15 |
| 336_D | 382_P | 1.059 | 0.15 |
| 519_P | 568_P | 1.059 | 0.15 |
| 224_A | 294_T | 1.059 | 0.15 |
| 3_P | 545_G | 1.058 | 0.15 |
| 289_T | 672_Y | 1.056 | 0.15 |
| 661_C | 676_A | 1.056 | 0.15 |
| 261_F | 318_R | 1.056 | 0.15 |
| 39_F | 716_L | 1.056 | 0.15 |
| 28_P | 257_E | 1.055 | 0.15 |
| 583_L | 660_F | 1.054 | 0.15 |
| 84_L | 714_K | 1.053 | 0.15 |
| 155_D | 505_S | 1.053 | 0.15 |
| 379_R | 618_E | 1.053 | 0.15 |
| 202_L | 231_I | 1.053 | 0.15 |
| 312_S | 400_L | 1.053 | 0.15 |
| 309_Y | 355_L | 1.052 | 0.15 |
| 150_A | 421_R | 1.052 | 0.15 |
| 163_L | 354_R | 1.051 | 0.15 |
| 289_T | 646_I | 1.050 | 0.15 |
| 402_V | 685_C | 1.050 | 0.15 |
| 553_L | 632_G | 1.050 | 0.15 |
| 565_V | 593_F | 1.050 | 0.15 |
| 225_I | 527_F | 1.049 | 0.15 |
| 407_L | 537_H | 1.049 | 0.15 |
| 323_P | 572_G | 1.049 | 0.15 |
| 82_V | 389_F | 1.048 | 0.15 |
| 195_F | 572_G | 1.048 | 0.15 |
| 170_G | 386_P | 1.048 | 0.15 |
| 170_G | 523_G | 1.048 | 0.15 |
| 14_A | 510_C | 1.048 | 0.15 |
| 188_N | 650_L | 1.048 | 0.15 |
| 315_L | 327_W | 1.048 | 0.15 |
| 362_F | 505_S | 1.048 | 0.15 |
| 280_T | 606_W | 1.048 | 0.15 |
| 176_L | 682_S | 1.047 | 0.15 |
| 257_E | 322_R | 1.047 | 0.15 |
| 325_V | 330_R | 1.047 | 0.15 |
| 583_L | 673_E | 1.047 | 0.15 |
| 386_P | 524_R | 1.046 | 0.15 |
| 162_E | 604_L | 1.045 | 0.15 |
| 602_G | 716_L | 1.045 | 0.15 |
| 1_S | 27_V | 1.045 | 0.15 |
| 1_S | 566_V | 1.044 | 0.15 |
| 333_N | 342_E | 1.044 | 0.15 |
| 225_I | 552_A | 1.044 | 0.15 |
| 158_R | 165_W | 1.044 | 0.15 |
| 91_G | 338_N | 1.042 | 0.14 |
| 85_R | 524_R | 1.042 | 0.14 |
| 227_L | 725_E | 1.042 | 0.14 |
| 369_V | 445_L | 1.042 | 0.14 |
| 241_L | 370_V | 1.042 | 0.14 |
| 304_M | 311_S | 1.041 | 0.14 |
| 654_L | 685_C | 1.041 | 0.14 |
| 162_E | 583_L | 1.040 | 0.14 |
| 131_A | 664_I | 1.039 | 0.14 |
| 450_N | 659_V | 1.038 | 0.14 |
| 356_I | 360_C | 1.038 | 0.14 |
| 583_L | 627_R | 1.038 | 0.14 |
| 412_P | 657_P | 1.037 | 0.14 |
| 192_T | 607_K | 1.035 | 0.14 |
| 214_S | 534_S | 1.035 | 0.14 |
| 588_F | 667_V | 1.035 | 0.14 |
| 330_R | 713_D | 1.033 | 0.14 |
| 21_I | 235_A | 1.032 | 0.14 |
| 198_L | 379_R | 1.032 | 0.14 |
| 198_L | 622_K | 1.031 | 0.14 |
| 170_G | 173_G | 1.030 | 0.14 |
| 399_E | 597_Q | 1.030 | 0.14 |
| 134_I | 402_V | 1.030 | 0.14 |
| 164_T | 574_C | 1.029 | 0.14 |
| 374_L | 406_V | 1.029 | 0.14 |
| 202_L | 644_A | 1.028 | 0.14 |
| 325_V | 713_D | 1.027 | 0.14 |
| 15_I | 332_L | 1.026 | 0.14 |
| 36_R | 389_F | 1.026 | 0.14 |
| 713_D | 718_Q | 1.026 | 0.14 |
| 65_F | 310_S | 1.025 | 0.14 |
| 289_T | 522_L | 1.025 | 0.14 |
| 441_L | 497_I | 1.025 | 0.14 |
| 158_R | 172_D | 1.024 | 0.14 |
| 418_T | 502_V | 1.024 | 0.14 |
| 325_V | 335_P | 1.024 | 0.14 |
| 715_Y | 718_Q | 1.023 | 0.14 |
| 132_G | 499_A | 1.023 | 0.14 |
| 104_S | 107_G | 1.022 | 0.14 |
| 81_L | 226_L | 1.021 | 0.14 |
| 15_I | 362_F | 1.021 | 0.14 |
| 119_V | 125_R | 1.021 | 0.14 |
| 8_V | 529_K | 1.021 | 0.14 |
| 272_C | 444_Y | 1.020 | 0.14 |
| 73_I | 504_L | 1.020 | 0.14 |
| 361_L | 718_Q | 1.020 | 0.14 |
| 198_L | 232_V | 1.020 | 0.14 |
| 236_V | 489_K | 1.020 | 0.14 |
| 60_I | 502_V | 1.019 | 0.14 |
| 503_A | 644_A | 1.019 | 0.14 |
| 217_T | 548_V | 1.019 | 0.14 |
| 75_L | 638_L | 1.018 | 0.14 |
| 15_I | 401_S | 1.018 | 0.14 |
| 35_Y | 722_V | 1.018 | 0.14 |
| 37_T | 192_T | 1.018 | 0.14 |
| 44_V | 633_L | 1.017 | 0.14 |
| 270_D | 284_R | 1.017 | 0.14 |
| 253_L | 306_Y | 1.017 | 0.14 |
| 35_Y | 196_A | 1.017 | 0.14 |
| 313_F | 713_D | 1.016 | 0.14 |
| 60_I | 689_L | 1.015 | 0.14 |
| 205_T | 691_L | 1.015 | 0.14 |
| 64_C | 608_L | 1.014 | 0.14 |
| 120_F | 123_L | 1.013 | 0.14 |
| 78_F | 265_C | 1.013 | 0.14 |
| 574_C | 653_F | 1.013 | 0.14 |
| 338_N | 354_R | 1.012 | 0.14 |
| 195_F | 607_K | 1.012 | 0.14 |
| 170_G | 524_R | 1.012 | 0.14 |
| 277_F | 284_R | 1.011 | 0.14 |
| 444_Y | 520_A | 1.011 | 0.14 |
| 21_I | 527_F | 1.011 | 0.14 |
| 36_R | 87_Q | 1.010 | 0.14 |
| 296_V | 555_S | 1.010 | 0.14 |
| 170_G | 339_P | 1.010 | 0.14 |
| 408_Q | 520_A | 1.010 | 0.14 |
| 317_L | 346_L | 1.010 | 0.14 |
| 8_V | 194_C | 1.009 | 0.13 |
| 247_M | 348_V | 1.009 | 0.13 |
| 370_V | 388_N | 1.009 | 0.13 |
| 17_A | 20_F | 1.009 | 0.13 |
| 168_L | 432_C | 1.008 | 0.13 |
| 544_I | 710_I | 1.008 | 0.13 |
| 177_F | 444_Y | 1.008 | 0.13 |
| 36_R | 113_N | 1.008 | 0.13 |
| 86_E | 703_I | 1.008 | 0.13 |
| 89_N | 435_F | 1.008 | 0.13 |
| 39_F | 519_P | 1.008 | 0.13 |
| 166_Q | 310_S | 1.007 | 0.13 |
| 253_L | 343_M | 1.007 | 0.13 |
| 363_F | 366_I | 1.007 | 0.13 |
| 121_E | 124_E | 1.006 | 0.13 |
| 331_N | 712_N | 1.006 | 0.13 |
| 406_V | 513_T | 1.004 | 0.13 |
| 8_V | 571_T | 1.004 | 0.13 |
| 271_V | 705_A | 1.004 | 0.13 |
| 562_P | 565_V | 1.003 | 0.13 |
| 14_A | 235_A | 1.003 | 0.13 |
| 522_L | 670_L | 1.003 | 0.13 |
| 169_L | 601_M | 1.002 | 0.13 |
| 418_T | 527_F | 1.002 | 0.13 |
| 133_R | 617_P | 1.000 | 0.13 |
| 260_F | 677_Y | 1.000 | 0.13 |
| 195_F | 442_E | 1.000 | 0.13 |
| 331_N | 538_E | 1.000 | 0.13 |
| 444_Y | 454_P | 1.000 | 0.13 |
| 79_I | 527_F | 1.000 | 0.13 |
| 412_P | 602_G | 1.000 | 0.13 |
| 641_K | 660_F | 1.000 | 0.13 |
Prob = P(contact | scaled_score, seq/len).
Scaled Score = (raw_score/average(raw_scores)).
- Text file of contact predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
- Import to GREMLIN BETA - features includes ability to upload PDB and latest P(contact) calculation based on eLife 2015 fitting to PDB data.
GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled Score > 1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-position alignment confidence. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | M | Cov | P(%) | HHΔ | |
| 3tuiA | 4 | 0.2828 | 5.7 | 0.99 | Contact Map |
| 4j72A | 2 | 0.0524 | 5.5 | 0.991 | Contact Map |
| 3wmgA | 1 | 0.2676 | 3.9 | 0.991 | Contact Map |
| 3wdoA | 1 | 0.2055 | 3.3 | 0.991 | Contact Map |
| 1lypA | 1 | 0.0386 | 3.2 | 0.992 | Contact Map |
| 2jpjA | 1 | 0.0345 | 3.1 | 0.992 | Contact Map |
| 2rm9A | 1 | 0.0276 | 3 | 0.992 | Contact Map |
| 2lcnA | 1 | 0.0262 | 2.8 | 0.992 | Contact Map |
| 1tzsX | 1 | 0.0069 | 2.8 | 0.992 | Contact Map |
| 2rmfA | 1 | 0.0414 | 2.5 | 0.992 | Contact Map |
Cov = coverage of hit
P(%) = probability
Sequence Conservation (Image Generated using WebLogo v3)