| DENV4 -force run |
| ID: | 1477594211 |
Query Sequence |
Download Alignment We filter this alignment to remove positions that have > 75% gaps before running GREMLIN. |
| Length: | 900 (891) | ||
| Sequences: | 91 (71.5) | ||
| Seq/Len: | 0.102 | ||
| Nf(neff/√len): | 2.4 |
Jackhmmer Results: (2016_04)
Sequences per length for each position, BEFORE the coverage/gap filter was applied
Legend: Dots above the red line, indicates positions where there is > 5 sequences per length (if visible, green bar = 20 seq/len). Point of this graphic is to give you an idea if resubmitting a sub-portion of your sequence might help increase the overall Seq/Len (which after applying the coverage filter is at: 0.102).
Sequences per length for each position, AFTER the coverage/gap filter was applied
Residue pairs sorted by coevolution strength:
Legend: The darker and larger the blue dots, the higher strength in covariance. Below we provide the list of the top [1.5 x length] covarying residues with sequence seperation > 3. The i and j are positions as given in the input sequence.
| i | j | Scaled score | Prob |
| 185_P | 188_P | 2.704 | 0.75 |
| 520_E | 716_K | 2.485 | 0.65 |
| 109_G | 113_P | 2.426 | 0.63 |
| 623_M | 644_V | 2.289 | 0.56 |
| 42_K | 49_S | 2.231 | 0.53 |
| 110_H | 113_P | 2.037 | 0.43 |
| 42_K | 46_K | 1.993 | 0.41 |
| 165_L | 197_L | 1.991 | 0.41 |
| 42_K | 45_L | 1.967 | 0.40 |
| 102_G | 126_L | 1.946 | 0.39 |
| 45_L | 49_S | 1.940 | 0.39 |
| 45_L | 50_K | 1.846 | 0.34 |
| 46_K | 49_S | 1.832 | 0.34 |
| 186_Y | 190_V | 1.822 | 0.33 |
| 186_Y | 189_T | 1.816 | 0.33 |
| 867_A | 871_V | 1.785 | 0.32 |
| 42_K | 48_G | 1.768 | 0.31 |
| 41_A | 45_L | 1.765 | 0.31 |
| 549_N | 616_E | 1.750 | 0.30 |
| 505_S | 615_M | 1.735 | 0.29 |
| 868_I | 884_M | 1.725 | 0.29 |
| 377_T | 884_M | 1.717 | 0.29 |
| 45_L | 48_G | 1.711 | 0.28 |
| 71_V | 75_G | 1.702 | 0.28 |
| 844_E | 847_W | 1.660 | 0.26 |
| 109_G | 112_E | 1.651 | 0.26 |
| 185_P | 189_T | 1.643 | 0.26 |
| 329_T | 776_A | 1.615 | 0.25 |
| 875_I | 880_Y | 1.610 | 0.24 |
| 184_N | 800_A | 1.596 | 0.24 |
| 750_R | 787_E | 1.587 | 0.24 |
| 26_E | 29_K | 1.576 | 0.23 |
| 42_K | 50_K | 1.572 | 0.23 |
| 44_A | 48_G | 1.555 | 0.22 |
| 43_S | 49_S | 1.554 | 0.22 |
| 185_P | 190_V | 1.544 | 0.22 |
| 11_E | 179_C | 1.533 | 0.22 |
| 843_R | 882_D | 1.533 | 0.22 |
| 76_K | 123_L | 1.525 | 0.21 |
| 21_D | 563_I | 1.515 | 0.21 |
| 123_L | 846_L | 1.513 | 0.21 |
| 200_K | 890_Y | 1.512 | 0.21 |
| 694_Q | 802_H | 1.498 | 0.21 |
| 7_E | 12_K | 1.463 | 0.19 |
| 41_A | 48_G | 1.450 | 0.19 |
| 551_E | 887_M | 1.443 | 0.19 |
| 70_M | 73_P | 1.441 | 0.19 |
| 514_R | 823_P | 1.437 | 0.19 |
| 165_L | 180_I | 1.436 | 0.19 |
| 44_A | 65_I | 1.429 | 0.18 |
| 835_E | 888_K | 1.428 | 0.18 |
| 179_C | 333_D | 1.423 | 0.18 |
| 27_E | 881_V | 1.422 | 0.18 |
| 282_Q | 286_E | 1.413 | 0.18 |
| 144_L | 179_C | 1.411 | 0.18 |
| 78_V | 703_N | 1.406 | 0.18 |
| 283_R | 335_I | 1.405 | 0.18 |
| 378_A | 616_E | 1.398 | 0.17 |
| 195_E | 754_C | 1.395 | 0.17 |
| 240_L | 423_S | 1.388 | 0.17 |
| 68_R | 795_T | 1.374 | 0.17 |
| 105_K | 870_Q | 1.356 | 0.16 |
| 29_K | 362_R | 1.347 | 0.16 |
| 348_P | 660_A | 1.343 | 0.16 |
| 764_S | 777_S | 1.343 | 0.16 |
| 585_P | 625_A | 1.342 | 0.16 |
| 362_R | 365_Q | 1.339 | 0.16 |
| 676_G | 777_S | 1.335 | 0.16 |
| 208_C | 696_E | 1.334 | 0.16 |
| 502_N | 511_G | 1.330 | 0.16 |
| 712_H | 766_M | 1.330 | 0.16 |
| 415_E | 429_S | 1.328 | 0.16 |
| 226_G | 259_G | 1.327 | 0.15 |
| 118_T | 429_S | 1.326 | 0.15 |
| 40_E | 46_K | 1.319 | 0.15 |
| 22_R | 29_K | 1.315 | 0.15 |
| 12_K | 26_E | 1.315 | 0.15 |
| 287_E | 306_H | 1.313 | 0.15 |
| 728_P | 774_R | 1.312 | 0.15 |
| 43_S | 48_G | 1.308 | 0.15 |
| 549_N | 841_G | 1.306 | 0.15 |
| 15_R | 20_L | 1.306 | 0.15 |
| 276_I | 887_M | 1.305 | 0.15 |
| 172_L | 175_K | 1.304 | 0.15 |
| 885_P | 890_Y | 1.303 | 0.15 |
| 23_K | 29_K | 1.298 | 0.15 |
| 24_E | 585_P | 1.296 | 0.15 |
| 306_H | 594_S | 1.295 | 0.15 |
| 204_N | 329_T | 1.292 | 0.15 |
| 41_A | 49_S | 1.290 | 0.15 |
| 21_D | 877_K | 1.290 | 0.15 |
| 416_E | 764_S | 1.287 | 0.14 |
| 342_A | 623_M | 1.286 | 0.14 |
| 49_S | 52_K | 1.284 | 0.14 |
| 440_A | 444_E | 1.280 | 0.14 |
| 841_G | 844_E | 1.279 | 0.14 |
| 194_L | 198_Q | 1.275 | 0.14 |
| 20_L | 41_A | 1.274 | 0.14 |
| 855_S | 887_M | 1.273 | 0.14 |
| 406_N | 417_Q | 1.272 | 0.14 |
| 285_Q | 871_V | 1.269 | 0.14 |
| 23_K | 644_V | 1.268 | 0.14 |
| 44_A | 49_S | 1.259 | 0.14 |
| 514_R | 549_N | 1.259 | 0.14 |
| 370_T | 629_I | 1.257 | 0.14 |
| 293_H | 589_V | 1.256 | 0.14 |
| 46_K | 563_I | 1.255 | 0.14 |
| 12_K | 32_G | 1.249 | 0.14 |
| 16_Q | 630_T | 1.245 | 0.13 |
| 119_Y | 124_V | 1.245 | 0.13 |
| 20_L | 264_S | 1.243 | 0.13 |
| 520_E | 703_N | 1.243 | 0.13 |
| 584_T | 589_V | 1.242 | 0.13 |
| 151_S | 157_E | 1.241 | 0.13 |
| 514_R | 616_E | 1.237 | 0.13 |
| 329_T | 764_S | 1.235 | 0.13 |
| 46_K | 510_E | 1.234 | 0.13 |
| 843_R | 847_W | 1.232 | 0.13 |
| 9_L | 890_Y | 1.228 | 0.13 |
| 291_T | 821_D | 1.227 | 0.13 |
| 29_K | 363_T | 1.224 | 0.13 |
| 670_P | 673_E | 1.222 | 0.13 |
| 215_T | 717_I | 1.221 | 0.13 |
| 116_M | 884_M | 1.221 | 0.13 |
| 40_E | 45_L | 1.221 | 0.13 |
| 43_S | 46_K | 1.220 | 0.13 |
| 72_K | 75_G | 1.219 | 0.13 |
| 124_V | 134_Y | 1.219 | 0.13 |
| 102_G | 138_E | 1.218 | 0.13 |
| 379_N | 423_S | 1.218 | 0.13 |
| 694_Q | 743_Q | 1.218 | 0.13 |
| 686_G | 890_Y | 1.215 | 0.13 |
| 634_M | 637_P | 1.215 | 0.13 |
| 20_L | 885_P | 1.214 | 0.13 |
| 866_T | 874_L | 1.214 | 0.13 |
| 281_L | 821_D | 1.213 | 0.13 |
| 19_S | 26_E | 1.210 | 0.13 |
| 415_E | 579_K | 1.210 | 0.13 |
| 193_E | 197_L | 1.209 | 0.13 |
| 570_K | 574_Q | 1.208 | 0.13 |
| 712_H | 756_G | 1.208 | 0.13 |
| 467_R | 801_H | 1.208 | 0.13 |
| 391_P | 495_D | 1.207 | 0.13 |
| 710_C | 730_R | 1.207 | 0.13 |
| 373_V | 871_V | 1.207 | 0.13 |
| 499_G | 716_K | 1.207 | 0.13 |
| 416_E | 888_K | 1.205 | 0.13 |
| 367_K | 684_D | 1.204 | 0.12 |
| 29_K | 654_D | 1.202 | 0.12 |
| 389_K | 511_G | 1.202 | 0.12 |
| 39_T | 505_S | 1.200 | 0.12 |
| 786_T | 879_E | 1.199 | 0.12 |
| 437_K | 448_E | 1.197 | 0.12 |
| 418_G | 430_R | 1.194 | 0.12 |
| 374_M | 531_Y | 1.193 | 0.12 |
| 33_I | 36_V | 1.193 | 0.12 |
| 489_L | 817_V | 1.191 | 0.12 |
| 36_V | 255_D | 1.188 | 0.12 |
| 444_E | 448_E | 1.187 | 0.12 |
| 7_E | 288_H | 1.187 | 0.12 |
| 48_G | 563_I | 1.183 | 0.12 |
| 45_L | 855_S | 1.183 | 0.12 |
| 228_I | 396_R | 1.183 | 0.12 |
| 69_G | 73_P | 1.183 | 0.12 |
| 281_L | 444_E | 1.182 | 0.12 |
| 289_K | 873_N | 1.182 | 0.12 |
| 16_Q | 244_T | 1.180 | 0.12 |
| 519_L | 667_V | 1.178 | 0.12 |
| 294_Y | 871_V | 1.177 | 0.12 |
| 490_G | 539_D | 1.175 | 0.12 |
| 194_L | 390_N | 1.175 | 0.12 |
| 329_T | 777_S | 1.175 | 0.12 |
| 262_T | 480_G | 1.174 | 0.12 |
| 324_V | 875_I | 1.170 | 0.12 |
| 601_S | 610_N | 1.170 | 0.12 |
| 310_E | 870_Q | 1.169 | 0.12 |
| 330_K | 841_G | 1.169 | 0.12 |
| 396_R | 719_M | 1.168 | 0.12 |
| 251_T | 273_D | 1.167 | 0.12 |
| 417_Q | 623_M | 1.161 | 0.12 |
| 709_F | 728_P | 1.160 | 0.12 |
| 510_E | 888_K | 1.159 | 0.12 |
| 670_P | 746_G | 1.159 | 0.12 |
| 7_E | 31_S | 1.157 | 0.11 |
| 102_G | 117_A | 1.154 | 0.11 |
| 109_G | 114_I | 1.153 | 0.11 |
| 670_P | 756_G | 1.152 | 0.11 |
| 184_N | 608_G | 1.152 | 0.11 |
| 257_D | 890_Y | 1.145 | 0.11 |
| 841_G | 847_W | 1.145 | 0.11 |
| 709_F | 774_R | 1.145 | 0.11 |
| 19_S | 22_R | 1.145 | 0.11 |
| 194_L | 437_K | 1.144 | 0.11 |
| 291_T | 444_E | 1.142 | 0.11 |
| 656_L | 712_H | 1.139 | 0.11 |
| 53_H | 118_T | 1.139 | 0.11 |
| 291_T | 659_M | 1.138 | 0.11 |
| 881_V | 892_A | 1.135 | 0.11 |
| 821_D | 837_I | 1.135 | 0.11 |
| 103_Y | 837_I | 1.135 | 0.11 |
| 284_L | 895_E | 1.134 | 0.11 |
| 6_G | 882_D | 1.132 | 0.11 |
| 34_L | 48_G | 1.132 | 0.11 |
| 21_D | 26_E | 1.132 | 0.11 |
| 597_D | 609_L | 1.132 | 0.11 |
| 589_V | 748_S | 1.132 | 0.11 |
| 463_G | 719_M | 1.132 | 0.11 |
| 41_A | 46_K | 1.131 | 0.11 |
| 226_G | 581_L | 1.129 | 0.11 |
| 290_E | 294_Y | 1.128 | 0.11 |
| 527_G | 673_E | 1.128 | 0.11 |
| 342_A | 670_P | 1.127 | 0.11 |
| 243_F | 285_Q | 1.126 | 0.11 |
| 105_K | 119_Y | 1.123 | 0.11 |
| 826_I | 893_P | 1.122 | 0.11 |
| 670_P | 747_W | 1.122 | 0.11 |
| 512_L | 628_V | 1.121 | 0.11 |
| 125_K | 510_E | 1.121 | 0.11 |
| 286_E | 444_E | 1.120 | 0.11 |
| 45_L | 51_I | 1.120 | 0.11 |
| 408_A | 810_M | 1.120 | 0.11 |
| 22_R | 314_T | 1.119 | 0.11 |
| 666_C | 795_T | 1.119 | 0.11 |
| 43_S | 117_A | 1.117 | 0.11 |
| 34_L | 645_E | 1.117 | 0.11 |
| 370_T | 684_D | 1.116 | 0.11 |
| 341_L | 417_Q | 1.115 | 0.11 |
| 165_L | 258_L | 1.115 | 0.11 |
| 513_H | 887_M | 1.114 | 0.11 |
| 716_K | 858_A | 1.114 | 0.11 |
| 91_M | 522_I | 1.114 | 0.11 |
| 382_W | 844_E | 1.113 | 0.11 |
| 730_R | 774_R | 1.113 | 0.11 |
| 65_I | 855_S | 1.112 | 0.11 |
| 123_L | 725_L | 1.112 | 0.11 |
| 846_L | 886_V | 1.112 | 0.11 |
| 858_A | 886_V | 1.111 | 0.11 |
| 413_F | 859_T | 1.110 | 0.11 |
| 16_Q | 23_K | 1.110 | 0.11 |
| 226_G | 365_Q | 1.109 | 0.11 |
| 175_K | 832_H | 1.109 | 0.11 |
| 406_N | 795_T | 1.107 | 0.11 |
| 585_P | 832_H | 1.107 | 0.11 |
| 285_Q | 885_P | 1.106 | 0.10 |
| 490_G | 509_G | 1.105 | 0.10 |
| 509_G | 539_D | 1.105 | 0.10 |
| 20_L | 243_F | 1.104 | 0.10 |
| 328_L | 720_K | 1.102 | 0.10 |
| 184_N | 862_K | 1.102 | 0.10 |
| 46_K | 50_K | 1.101 | 0.10 |
| 348_P | 518_I | 1.100 | 0.10 |
| 342_A | 756_G | 1.099 | 0.10 |
| 123_L | 271_K | 1.098 | 0.10 |
| 879_E | 885_P | 1.098 | 0.10 |
| 40_E | 65_I | 1.097 | 0.10 |
| 830_P | 884_M | 1.096 | 0.10 |
| 12_K | 869_T | 1.095 | 0.10 |
| 559_P | 562_K | 1.095 | 0.10 |
| 156_I | 887_M | 1.094 | 0.10 |
| 152_S | 890_Y | 1.093 | 0.10 |
| 20_L | 833_S | 1.093 | 0.10 |
| 34_L | 636_N | 1.092 | 0.10 |
| 885_P | 892_A | 1.091 | 0.10 |
| 429_S | 767_Y | 1.089 | 0.10 |
| 48_G | 881_V | 1.089 | 0.10 |
| 153_N | 190_V | 1.089 | 0.10 |
| 858_A | 887_M | 1.088 | 0.10 |
| 179_C | 210_L | 1.087 | 0.10 |
| 21_D | 32_G | 1.087 | 0.10 |
| 34_L | 39_T | 1.086 | 0.10 |
| 118_T | 415_E | 1.086 | 0.10 |
| 330_K | 412_V | 1.085 | 0.10 |
| 20_L | 26_E | 1.085 | 0.10 |
| 373_V | 641_K | 1.084 | 0.10 |
| 105_K | 220_W | 1.084 | 0.10 |
| 118_T | 421_S | 1.083 | 0.10 |
| 417_Q | 654_D | 1.083 | 0.10 |
| 657_K | 871_V | 1.082 | 0.10 |
| 109_G | 115_P | 1.082 | 0.10 |
| 21_D | 96_N | 1.082 | 0.10 |
| 143_L | 348_P | 1.081 | 0.10 |
| 251_T | 370_T | 1.081 | 0.10 |
| 47_D | 873_N | 1.080 | 0.10 |
| 75_G | 375_T | 1.079 | 0.10 |
| 195_E | 199_R | 1.079 | 0.10 |
| 208_C | 404_R | 1.079 | 0.10 |
| 97_V | 179_C | 1.078 | 0.10 |
| 523_D | 725_L | 1.078 | 0.10 |
| 31_S | 873_N | 1.078 | 0.10 |
| 42_K | 47_D | 1.078 | 0.10 |
| 237_K | 823_P | 1.077 | 0.10 |
| 590_M | 880_Y | 1.077 | 0.10 |
| 868_I | 885_P | 1.076 | 0.10 |
| 7_E | 893_P | 1.074 | 0.10 |
| 32_G | 748_S | 1.074 | 0.10 |
| 382_W | 843_R | 1.074 | 0.10 |
| 703_N | 836_D | 1.073 | 0.10 |
| 172_L | 703_N | 1.073 | 0.10 |
| 62_I | 499_G | 1.071 | 0.10 |
| 157_E | 161_T | 1.071 | 0.10 |
| 562_K | 786_T | 1.071 | 0.10 |
| 143_L | 176_P | 1.071 | 0.10 |
| 235_T | 415_E | 1.069 | 0.10 |
| 553_I | 887_M | 1.069 | 0.10 |
| 22_R | 116_M | 1.069 | 0.10 |
| 639_G | 645_E | 1.068 | 0.10 |
| 178_F | 222_S | 1.065 | 0.10 |
| 401_S | 888_K | 1.065 | 0.10 |
| 449_S | 481_A | 1.065 | 0.10 |
| 50_K | 877_K | 1.064 | 0.10 |
| 7_E | 688_V | 1.064 | 0.10 |
| 9_L | 726_V | 1.063 | 0.10 |
| 281_L | 871_V | 1.060 | 0.10 |
| 727_V | 736_I | 1.059 | 0.10 |
| 273_D | 890_Y | 1.058 | 0.10 |
| 102_G | 210_L | 1.054 | 0.10 |
| 368_P | 632_D | 1.054 | 0.10 |
| 71_V | 74_K | 1.053 | 0.10 |
| 34_L | 46_K | 1.053 | 0.10 |
| 31_S | 54_A | 1.051 | 0.09 |
| 530_M | 669_K | 1.051 | 0.09 |
| 71_V | 764_S | 1.050 | 0.09 |
| 34_L | 881_V | 1.049 | 0.09 |
| 473_A | 578_V | 1.049 | 0.09 |
| 12_K | 29_K | 1.049 | 0.09 |
| 382_W | 847_W | 1.048 | 0.09 |
| 49_S | 879_E | 1.048 | 0.09 |
| 391_P | 842_K | 1.048 | 0.09 |
| 393_L | 693_P | 1.046 | 0.09 |
| 445_G | 728_P | 1.046 | 0.09 |
| 288_H | 416_E | 1.045 | 0.09 |
| 471_S | 506_G | 1.045 | 0.09 |
| 46_K | 879_E | 1.045 | 0.09 |
| 869_T | 873_N | 1.044 | 0.09 |
| 688_V | 812_K | 1.044 | 0.09 |
| 101_K | 123_L | 1.044 | 0.09 |
| 283_R | 890_Y | 1.044 | 0.09 |
| 15_R | 23_K | 1.044 | 0.09 |
| 238_M | 636_N | 1.044 | 0.09 |
| 490_G | 730_R | 1.043 | 0.09 |
| 539_D | 730_R | 1.043 | 0.09 |
| 193_E | 430_R | 1.043 | 0.09 |
| 549_N | 844_E | 1.043 | 0.09 |
| 172_L | 377_T | 1.043 | 0.09 |
| 880_Y | 890_Y | 1.043 | 0.09 |
| 73_P | 677_T | 1.041 | 0.09 |
| 563_I | 892_A | 1.041 | 0.09 |
| 41_A | 50_K | 1.041 | 0.09 |
| 102_G | 130_V | 1.041 | 0.09 |
| 19_S | 629_I | 1.040 | 0.09 |
| 19_S | 45_L | 1.040 | 0.09 |
| 27_E | 109_G | 1.040 | 0.09 |
| 15_R | 529_L | 1.039 | 0.09 |
| 688_V | 726_V | 1.038 | 0.09 |
| 601_S | 730_R | 1.038 | 0.09 |
| 610_N | 730_R | 1.038 | 0.09 |
| 193_E | 198_Q | 1.037 | 0.09 |
| 143_L | 168_V | 1.037 | 0.09 |
| 291_T | 879_E | 1.037 | 0.09 |
| 16_Q | 20_L | 1.035 | 0.09 |
| 705_Q | 836_D | 1.034 | 0.09 |
| 724_S | 885_P | 1.034 | 0.09 |
| 16_Q | 441_L | 1.034 | 0.09 |
| 589_V | 684_D | 1.033 | 0.09 |
| 568_I | 731_N | 1.033 | 0.09 |
| 113_P | 890_Y | 1.033 | 0.09 |
| 710_C | 774_R | 1.033 | 0.09 |
| 47_D | 522_I | 1.033 | 0.09 |
| 166_K | 233_N | 1.032 | 0.09 |
| 445_G | 774_R | 1.032 | 0.09 |
| 486_F | 861_A | 1.031 | 0.09 |
| 159_G | 416_E | 1.031 | 0.09 |
| 516_G | 601_S | 1.031 | 0.09 |
| 516_G | 610_N | 1.031 | 0.09 |
| 144_L | 631_Q | 1.031 | 0.09 |
| 418_G | 552_L | 1.031 | 0.09 |
| 286_E | 891_S | 1.031 | 0.09 |
| 379_N | 418_G | 1.031 | 0.09 |
| 237_K | 623_M | 1.030 | 0.09 |
| 111_E | 114_I | 1.030 | 0.09 |
| 418_G | 891_S | 1.030 | 0.09 |
| 489_L | 511_G | 1.030 | 0.09 |
| 276_I | 481_A | 1.029 | 0.09 |
| 130_V | 228_I | 1.028 | 0.09 |
| 824_N | 879_E | 1.027 | 0.09 |
| 339_T | 869_T | 1.027 | 0.09 |
| 512_L | 756_G | 1.026 | 0.09 |
| 373_V | 629_I | 1.025 | 0.09 |
| 235_T | 641_K | 1.025 | 0.09 |
| 616_E | 715_H | 1.025 | 0.09 |
| 347_T | 458_R | 1.025 | 0.09 |
| 628_V | 833_S | 1.024 | 0.09 |
| 873_N | 893_P | 1.024 | 0.09 |
| 134_Y | 870_Q | 1.024 | 0.09 |
| 43_S | 877_K | 1.023 | 0.09 |
| 45_L | 63_R | 1.023 | 0.09 |
| 863_N | 870_Q | 1.023 | 0.09 |
| 322_N | 344_T | 1.023 | 0.09 |
| 514_R | 844_E | 1.023 | 0.09 |
| 710_C | 728_P | 1.022 | 0.09 |
| 588_A | 629_I | 1.021 | 0.09 |
| 23_K | 446_K | 1.020 | 0.09 |
| 105_K | 129_G | 1.020 | 0.09 |
| 15_R | 891_S | 1.018 | 0.09 |
| 841_G | 888_K | 1.018 | 0.09 |
| 416_E | 451_V | 1.018 | 0.09 |
| 16_Q | 881_V | 1.018 | 0.09 |
| 194_L | 387_K | 1.018 | 0.09 |
| 105_K | 612_F | 1.018 | 0.09 |
| 143_L | 221_V | 1.018 | 0.09 |
| 30_R | 451_V | 1.018 | 0.09 |
| 542_I | 777_S | 1.018 | 0.09 |
| 95_K | 388_K | 1.017 | 0.09 |
| 625_A | 890_Y | 1.017 | 0.09 |
| 831_V | 879_E | 1.016 | 0.09 |
| 473_A | 580_V | 1.016 | 0.09 |
| 11_E | 311_A | 1.015 | 0.09 |
| 6_G | 12_K | 1.015 | 0.09 |
| 277_I | 282_Q | 1.014 | 0.09 |
| 520_E | 891_S | 1.014 | 0.09 |
| 162_L | 430_R | 1.013 | 0.09 |
| 588_A | 777_S | 1.013 | 0.09 |
| 489_L | 502_N | 1.012 | 0.09 |
| 15_R | 334_M | 1.011 | 0.09 |
| 31_S | 712_H | 1.011 | 0.09 |
| 107_G | 129_G | 1.011 | 0.09 |
| 118_T | 864_I | 1.011 | 0.09 |
| 12_K | 34_L | 1.011 | 0.09 |
| 65_I | 155_T | 1.010 | 0.09 |
| 423_S | 748_S | 1.010 | 0.09 |
| 29_K | 712_H | 1.010 | 0.09 |
| 608_G | 792_S | 1.010 | 0.09 |
| 874_L | 887_M | 1.010 | 0.09 |
| 11_E | 20_L | 1.009 | 0.09 |
| 16_Q | 563_I | 1.008 | 0.09 |
| 178_F | 511_G | 1.007 | 0.09 |
| 869_T | 874_L | 1.007 | 0.09 |
| 435_V | 734_E | 1.006 | 0.09 |
| 641_K | 686_G | 1.006 | 0.09 |
| 854_L | 892_A | 1.006 | 0.09 |
| 236_S | 660_A | 1.006 | 0.09 |
| 42_K | 318_S | 1.005 | 0.09 |
| 373_V | 505_S | 1.005 | 0.09 |
| 275_T | 286_E | 1.004 | 0.09 |
| 437_K | 748_S | 1.003 | 0.09 |
| 495_D | 740_R | 1.003 | 0.09 |
| 16_Q | 72_K | 1.003 | 0.09 |
| 450_C | 721_D | 1.003 | 0.09 |
| 105_K | 126_L | 1.002 | 0.09 |
| 112_E | 129_G | 1.002 | 0.09 |
| 24_E | 50_K | 1.001 | 0.09 |
| 210_L | 887_M | 1.000 | 0.09 |
Prob = P(contact | scaled_score, seq/len).
Scaled Score = (raw_score/average(raw_scores)).
- Text file of contact predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
- Import to GREMLIN BETA - features includes ability to upload PDB and latest P(contact) calculation based on eLife 2015 fitting to PDB data.
GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled Score > 1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-position alignment confidence. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | M | Cov | P(%) | HHΔ | |
| 4v0qA | 1 | 0.9444 | 100 | 0.203 | Contact Map |
| 4k6mA | 2 | 0.9767 | 100 | 0.209 | Contact Map |
| 4hdhA | 2 | 0.6789 | 100 | 0.338 | Contact Map |
| 4hhjA | 1 | 0.6533 | 100 | 0.349 | Contact Map |
| 2cjqA | 1 | 0.5722 | 100 | 0.727 | Contact Map |
| 3hkwA | 3 | 0.5622 | 100 | 0.801 | Contact Map |
| 3lkzA | 2 | 0.2878 | 100 | 0.851 | Contact Map |
| 2px2A | 2 | 0.2811 | 100 | 0.865 | Contact Map |
| 4r8rA | 2 | 0.2844 | 100 | 0.865 | Contact Map |
| 3eldA | 1 | 0.3056 | 100 | 0.887 | Contact Map |
Cov = coverage of hit
P(%) = probability
Sequence Conservation (Image Generated using WebLogo v3)