| asap1_human_d801_950 -force run |
| ID: | 1450534709 |
Query Sequence |
Download Alignment We filter this alignment to remove positions that have > 75% gaps before running GREMLIN. |
| Length: | 979 (912) | ||
| Sequences: | 89 (60.2) | ||
| Seq/Len: | 0.098 | ||
| Nf(neff/√len): | 2.0 |
HHblits Results: (2015_06)
Sequences per length for each position, BEFORE the coverage/gap filter was applied
Legend: Dots above the red line, indicates positions where there is > 5 sequences per length (if visible, green bar = 20 seq/len). Point of this graphic is to give you an idea if resubmitting a sub-portion of your sequence might help increase the overall Seq/Len (which after applying the coverage filter is at: 0.098).
Sequences per length for each position, AFTER the coverage/gap filter was applied
Residue pairs sorted by coevolution strength:
Legend: The darker and larger the blue dots, the higher strength in covariance. Below we provide the list of the top [1.5 x length] covarying residues with sequence seperation > 3. The i and j are positions as given in the input sequence.
| i | j | Scaled score | Prob |
| 37_D | 46_F | 2.222 | 0.51 |
| 30_F | 37_D | 2.203 | 0.50 |
| 34_T | 37_D | 1.969 | 0.39 |
| 30_F | 44_S | 1.952 | 0.38 |
| 30_F | 46_F | 1.921 | 0.37 |
| 37_D | 41_P | 1.920 | 0.37 |
| 21_M | 37_D | 1.887 | 0.35 |
| 29_E | 34_T | 1.828 | 0.32 |
| 27_V | 37_D | 1.820 | 0.32 |
| 37_D | 44_S | 1.817 | 0.32 |
| 410_V | 413_N | 1.806 | 0.32 |
| 34_T | 41_P | 1.767 | 0.30 |
| 475_I | 496_L | 1.766 | 0.30 |
| 22_P | 36_E | 1.744 | 0.29 |
| 21_M | 30_F | 1.737 | 0.29 |
| 475_I | 478_S | 1.729 | 0.28 |
| 34_T | 46_F | 1.717 | 0.28 |
| 41_P | 46_F | 1.710 | 0.28 |
| 543_I | 546_K | 1.696 | 0.27 |
| 30_F | 34_T | 1.694 | 0.27 |
| 21_M | 46_F | 1.683 | 0.26 |
| 21_M | 27_V | 1.642 | 0.25 |
| 40_S | 46_F | 1.641 | 0.25 |
| 478_S | 496_L | 1.633 | 0.25 |
| 265_I | 720_D | 1.631 | 0.25 |
| 27_V | 46_F | 1.628 | 0.24 |
| 37_D | 54_R | 1.625 | 0.24 |
| 30_F | 41_P | 1.611 | 0.24 |
| 29_E | 37_D | 1.604 | 0.24 |
| 36_E | 46_F | 1.601 | 0.23 |
| 21_M | 36_E | 1.598 | 0.23 |
| 539_R | 546_K | 1.588 | 0.23 |
| 907_P | 910_R | 1.568 | 0.22 |
| 409_S | 413_N | 1.567 | 0.22 |
| 203_I | 209_K | 1.564 | 0.22 |
| 41_P | 44_S | 1.563 | 0.22 |
| 142_N | 146_T | 1.562 | 0.22 |
| 27_V | 30_F | 1.548 | 0.22 |
| 27_V | 41_P | 1.544 | 0.21 |
| 37_D | 40_S | 1.539 | 0.21 |
| 34_T | 44_S | 1.522 | 0.21 |
| 30_F | 36_E | 1.511 | 0.20 |
| 141_H | 314_M | 1.505 | 0.20 |
| 36_E | 53_C | 1.503 | 0.20 |
| 37_D | 53_C | 1.494 | 0.20 |
| 520_E | 534_S | 1.485 | 0.20 |
| 29_E | 36_E | 1.484 | 0.20 |
| 29_E | 41_P | 1.484 | 0.20 |
| 36_E | 41_P | 1.478 | 0.19 |
| 21_M | 34_T | 1.474 | 0.19 |
| 536_M | 546_K | 1.468 | 0.19 |
| 27_V | 34_T | 1.466 | 0.19 |
| 941_G | 949_E | 1.460 | 0.19 |
| 539_R | 543_I | 1.459 | 0.19 |
| 74_V | 236_L | 1.458 | 0.19 |
| 731_E | 734_P | 1.456 | 0.19 |
| 451_N | 456_D | 1.453 | 0.19 |
| 34_T | 40_S | 1.452 | 0.19 |
| 935_E | 941_G | 1.431 | 0.18 |
| 165_P | 206_E | 1.426 | 0.18 |
| 74_V | 577_L | 1.416 | 0.17 |
| 922_V | 955_W | 1.409 | 0.17 |
| 244_Y | 381_D | 1.409 | 0.17 |
| 29_E | 46_F | 1.402 | 0.17 |
| 29_E | 40_S | 1.395 | 0.17 |
| 957_G | 970_P | 1.395 | 0.17 |
| 281_E | 471_I | 1.391 | 0.17 |
| 451_N | 454_C | 1.388 | 0.17 |
| 617_L | 622_F | 1.388 | 0.17 |
| 283_K | 314_M | 1.385 | 0.17 |
| 46_F | 54_R | 1.384 | 0.17 |
| 364_Q | 382_K | 1.383 | 0.17 |
| 92_E | 253_D | 1.370 | 0.16 |
| 487_H | 501_T | 1.368 | 0.16 |
| 512_N | 520_E | 1.367 | 0.16 |
| 37_D | 43_T | 1.359 | 0.16 |
| 520_E | 523_L | 1.357 | 0.16 |
| 21_M | 41_P | 1.349 | 0.16 |
| 959_I | 965_R | 1.349 | 0.16 |
| 413_N | 450_G | 1.348 | 0.16 |
| 27_V | 44_S | 1.342 | 0.15 |
| 483_E | 499_L | 1.337 | 0.15 |
| 36_E | 44_S | 1.335 | 0.15 |
| 407_W | 410_V | 1.335 | 0.15 |
| 30_F | 54_R | 1.335 | 0.15 |
| 410_V | 450_G | 1.333 | 0.15 |
| 255_L | 280_D | 1.331 | 0.15 |
| 229_K | 236_L | 1.326 | 0.15 |
| 27_V | 36_E | 1.320 | 0.15 |
| 407_W | 413_N | 1.320 | 0.15 |
| 442_I | 449_P | 1.313 | 0.15 |
| 108_S | 612_A | 1.311 | 0.15 |
| 30_F | 40_S | 1.308 | 0.15 |
| 64_L | 67_D | 1.308 | 0.15 |
| 475_I | 491_I | 1.304 | 0.14 |
| 37_D | 50_L | 1.300 | 0.14 |
| 284_K | 696_K | 1.300 | 0.14 |
| 34_T | 54_R | 1.296 | 0.14 |
| 182_K | 290_R | 1.296 | 0.14 |
| 905_P | 910_R | 1.282 | 0.14 |
| 223_I | 435_E | 1.280 | 0.14 |
| 46_F | 49_R | 1.277 | 0.14 |
| 159_K | 166_F | 1.273 | 0.14 |
| 156_K | 383_K | 1.273 | 0.14 |
| 21_M | 44_S | 1.270 | 0.14 |
| 29_E | 53_C | 1.267 | 0.14 |
| 967_G | 970_P | 1.266 | 0.14 |
| 21_M | 54_R | 1.266 | 0.14 |
| 478_S | 491_I | 1.262 | 0.13 |
| 365_P | 387_L | 1.260 | 0.13 |
| 29_E | 604_A | 1.259 | 0.13 |
| 205_E | 922_V | 1.254 | 0.13 |
| 512_N | 516_N | 1.252 | 0.13 |
| 543_I | 547_Y | 1.249 | 0.13 |
| 36_E | 40_S | 1.246 | 0.13 |
| 320_N | 357_S | 1.245 | 0.13 |
| 451_N | 457_C | 1.245 | 0.13 |
| 253_D | 256_K | 1.244 | 0.13 |
| 214_F | 218_M | 1.243 | 0.13 |
| 575_D | 579_L | 1.241 | 0.13 |
| 184_K | 197_E | 1.239 | 0.13 |
| 67_D | 76_K | 1.234 | 0.13 |
| 22_P | 41_P | 1.233 | 0.13 |
| 413_N | 451_N | 1.232 | 0.13 |
| 34_T | 53_C | 1.232 | 0.13 |
| 21_M | 40_S | 1.230 | 0.13 |
| 198_I | 322_E | 1.228 | 0.13 |
| 922_V | 946_V | 1.228 | 0.13 |
| 481_H | 490_R | 1.225 | 0.13 |
| 41_P | 53_C | 1.225 | 0.13 |
| 437_L | 454_C | 1.225 | 0.13 |
| 587_V | 591_E | 1.223 | 0.13 |
| 161_D | 174_E | 1.222 | 0.13 |
| 931_D | 935_E | 1.219 | 0.13 |
| 930_A | 934_D | 1.218 | 0.12 |
| 243_Y | 971_V | 1.217 | 0.12 |
| 29_E | 44_S | 1.216 | 0.12 |
| 67_D | 71_L | 1.215 | 0.12 |
| 516_N | 520_E | 1.214 | 0.12 |
| 482_R | 490_R | 1.212 | 0.12 |
| 36_E | 43_T | 1.212 | 0.12 |
| 410_V | 451_N | 1.211 | 0.12 |
| 26_S | 46_F | 1.210 | 0.12 |
| 30_F | 50_L | 1.210 | 0.12 |
| 536_M | 543_I | 1.210 | 0.12 |
| 970_P | 974_V | 1.207 | 0.12 |
| 450_G | 456_D | 1.207 | 0.12 |
| 98_V | 979_D | 1.206 | 0.12 |
| 25_I | 41_P | 1.205 | 0.12 |
| 579_L | 719_D | 1.205 | 0.12 |
| 21_M | 29_E | 1.203 | 0.12 |
| 22_P | 29_E | 1.201 | 0.12 |
| 934_D | 954_W | 1.198 | 0.12 |
| 491_I | 496_L | 1.198 | 0.12 |
| 481_H | 489_S | 1.197 | 0.12 |
| 618_H | 623_L | 1.195 | 0.12 |
| 30_F | 43_T | 1.194 | 0.12 |
| 46_F | 53_C | 1.192 | 0.12 |
| 43_T | 46_F | 1.192 | 0.12 |
| 236_L | 720_D | 1.191 | 0.12 |
| 33_E | 38_Y | 1.189 | 0.12 |
| 190_Q | 440_A | 1.188 | 0.12 |
| 156_K | 937_T | 1.188 | 0.12 |
| 22_P | 37_D | 1.186 | 0.12 |
| 965_R | 970_P | 1.186 | 0.12 |
| 474_C | 481_H | 1.180 | 0.12 |
| 550_H | 742_S | 1.180 | 0.12 |
| 539_R | 547_Y | 1.180 | 0.12 |
| 214_F | 282_E | 1.180 | 0.12 |
| 482_R | 489_S | 1.179 | 0.12 |
| 474_C | 490_R | 1.179 | 0.12 |
| 37_D | 49_R | 1.178 | 0.12 |
| 29_E | 33_E | 1.176 | 0.12 |
| 243_Y | 275_I | 1.175 | 0.12 |
| 391_N | 977_L | 1.175 | 0.12 |
| 481_H | 493_S | 1.173 | 0.12 |
| 481_H | 497_D | 1.173 | 0.12 |
| 407_W | 411_L | 1.171 | 0.11 |
| 606_H | 626_N | 1.169 | 0.11 |
| 120_K | 167_D | 1.169 | 0.11 |
| 524_P | 550_H | 1.169 | 0.11 |
| 102_F | 424_R | 1.166 | 0.11 |
| 115_G | 940_E | 1.166 | 0.11 |
| 25_I | 34_T | 1.165 | 0.11 |
| 382_K | 403_D | 1.165 | 0.11 |
| 490_R | 493_S | 1.164 | 0.11 |
| 490_R | 497_D | 1.164 | 0.11 |
| 86_Q | 223_I | 1.163 | 0.11 |
| 536_M | 539_R | 1.162 | 0.11 |
| 345_R | 352_G | 1.162 | 0.11 |
| 160_G | 166_F | 1.159 | 0.11 |
| 40_S | 44_S | 1.156 | 0.11 |
| 242_K | 261_L | 1.155 | 0.11 |
| 617_L | 621_D | 1.155 | 0.11 |
| 83_N | 403_D | 1.155 | 0.11 |
| 36_E | 54_R | 1.154 | 0.11 |
| 774_I | 781_D | 1.153 | 0.11 |
| 34_T | 43_T | 1.153 | 0.11 |
| 474_C | 482_R | 1.152 | 0.11 |
| 349_V | 723_D | 1.151 | 0.11 |
| 493_S | 497_D | 1.151 | 0.11 |
| 325_S | 661_P | 1.151 | 0.11 |
| 78_V | 89_V | 1.151 | 0.11 |
| 154_D | 166_F | 1.150 | 0.11 |
| 43_T | 53_C | 1.150 | 0.11 |
| 64_L | 76_K | 1.150 | 0.11 |
| 391_N | 598_Q | 1.149 | 0.11 |
| 41_P | 50_L | 1.149 | 0.11 |
| 245_H | 629_N | 1.148 | 0.11 |
| 621_D | 654_K | 1.147 | 0.11 |
| 506_L | 515_F | 1.147 | 0.11 |
| 380_E | 678_K | 1.147 | 0.11 |
| 905_P | 909_P | 1.146 | 0.11 |
| 482_R | 493_S | 1.145 | 0.11 |
| 482_R | 497_D | 1.145 | 0.11 |
| 340_K | 721_L | 1.144 | 0.11 |
| 438_T | 455_C | 1.144 | 0.11 |
| 961_G | 965_R | 1.142 | 0.11 |
| 198_I | 236_L | 1.142 | 0.11 |
| 128_L | 376_K | 1.141 | 0.11 |
| 89_V | 92_E | 1.141 | 0.11 |
| 121_F | 180_I | 1.140 | 0.11 |
| 476_E | 487_H | 1.140 | 0.11 |
| 450_G | 454_C | 1.139 | 0.11 |
| 474_C | 489_S | 1.138 | 0.11 |
| 410_V | 415_K | 1.136 | 0.11 |
| 469_L | 472_L | 1.136 | 0.11 |
| 411_L | 415_K | 1.135 | 0.11 |
| 113_D | 122_S | 1.135 | 0.11 |
| 490_R | 504_L | 1.134 | 0.11 |
| 29_E | 43_T | 1.134 | 0.11 |
| 376_K | 389_S | 1.133 | 0.11 |
| 481_H | 504_L | 1.132 | 0.11 |
| 489_S | 493_S | 1.131 | 0.11 |
| 489_S | 497_D | 1.131 | 0.11 |
| 22_P | 27_V | 1.131 | 0.11 |
| 927_D | 947_T | 1.130 | 0.11 |
| 244_Y | 288_A | 1.129 | 0.11 |
| 138_G | 142_N | 1.129 | 0.11 |
| 141_H | 283_K | 1.128 | 0.11 |
| 442_I | 552_F | 1.128 | 0.11 |
| 922_V | 951_D | 1.128 | 0.11 |
| 506_L | 520_E | 1.128 | 0.11 |
| 512_N | 534_S | 1.128 | 0.11 |
| 143_V | 661_P | 1.128 | 0.11 |
| 27_V | 54_R | 1.127 | 0.11 |
| 203_I | 214_F | 1.124 | 0.11 |
| 250_F | 266_E | 1.123 | 0.11 |
| 151_L | 254_G | 1.123 | 0.11 |
| 22_P | 46_F | 1.123 | 0.11 |
| 186_E | 241_I | 1.121 | 0.11 |
| 367_K | 792_P | 1.121 | 0.11 |
| 27_V | 40_S | 1.121 | 0.11 |
| 38_Y | 49_R | 1.121 | 0.11 |
| 46_F | 50_L | 1.120 | 0.11 |
| 101_K | 117_A | 1.120 | 0.11 |
| 36_E | 50_L | 1.119 | 0.10 |
| 969_F | 973_F | 1.118 | 0.10 |
| 724_K | 937_T | 1.118 | 0.10 |
| 174_E | 941_G | 1.117 | 0.10 |
| 482_R | 504_L | 1.116 | 0.10 |
| 38_Y | 48_T | 1.116 | 0.10 |
| 417_E | 459_S | 1.116 | 0.10 |
| 409_S | 450_G | 1.114 | 0.10 |
| 606_H | 617_L | 1.111 | 0.10 |
| 608_A | 617_L | 1.107 | 0.10 |
| 555_K | 574_R | 1.107 | 0.10 |
| 410_V | 422_A | 1.106 | 0.10 |
| 585_E | 589_L | 1.106 | 0.10 |
| 466_S | 481_H | 1.105 | 0.10 |
| 466_S | 490_R | 1.105 | 0.10 |
| 33_E | 43_T | 1.104 | 0.10 |
| 206_E | 718_D | 1.104 | 0.10 |
| 78_V | 148_D | 1.104 | 0.10 |
| 103_G | 131_L | 1.104 | 0.10 |
| 363_R | 367_K | 1.103 | 0.10 |
| 586_G | 696_K | 1.102 | 0.10 |
| 382_K | 688_L | 1.100 | 0.10 |
| 187_H | 243_Y | 1.099 | 0.10 |
| 489_S | 504_L | 1.099 | 0.10 |
| 965_R | 969_F | 1.099 | 0.10 |
| 468_N | 481_H | 1.098 | 0.10 |
| 409_S | 437_L | 1.098 | 0.10 |
| 474_C | 493_S | 1.097 | 0.10 |
| 474_C | 497_D | 1.097 | 0.10 |
| 451_N | 466_S | 1.097 | 0.10 |
| 941_G | 973_F | 1.097 | 0.10 |
| 321_K | 602_E | 1.097 | 0.10 |
| 269_A | 311_G | 1.097 | 0.10 |
| 30_F | 53_C | 1.096 | 0.10 |
| 50_L | 53_C | 1.096 | 0.10 |
| 529_K | 534_S | 1.096 | 0.10 |
| 141_H | 495_E | 1.096 | 0.10 |
| 413_N | 456_D | 1.095 | 0.10 |
| 546_K | 570_A | 1.094 | 0.10 |
| 462_P | 469_L | 1.094 | 0.10 |
| 113_D | 120_K | 1.093 | 0.10 |
| 368_L | 375_V | 1.091 | 0.10 |
| 475_I | 507_A | 1.089 | 0.10 |
| 520_E | 529_K | 1.089 | 0.10 |
| 295_S | 945_I | 1.089 | 0.10 |
| 957_G | 965_R | 1.089 | 0.10 |
| 702_H | 705_Y | 1.088 | 0.10 |
| 466_S | 482_R | 1.088 | 0.10 |
| 468_N | 490_R | 1.088 | 0.10 |
| 638_N | 649_K | 1.087 | 0.10 |
| 413_N | 422_A | 1.086 | 0.10 |
| 200_G | 294_K | 1.086 | 0.10 |
| 441_I | 448_L | 1.085 | 0.10 |
| 225_V | 963_P | 1.084 | 0.10 |
| 476_E | 501_T | 1.083 | 0.10 |
| 602_E | 621_D | 1.083 | 0.10 |
| 159_K | 376_K | 1.082 | 0.10 |
| 392_R | 395_H | 1.082 | 0.10 |
| 212_R | 946_V | 1.081 | 0.10 |
| 102_F | 916_K | 1.080 | 0.10 |
| 468_N | 493_S | 1.079 | 0.10 |
| 468_N | 497_D | 1.079 | 0.10 |
| 24_Q | 259_D | 1.078 | 0.10 |
| 33_E | 44_S | 1.078 | 0.10 |
| 160_G | 165_P | 1.077 | 0.10 |
| 474_C | 504_L | 1.077 | 0.10 |
| 942_E | 959_I | 1.076 | 0.10 |
| 921_R | 935_E | 1.076 | 0.10 |
| 33_E | 37_D | 1.076 | 0.10 |
| 437_L | 451_N | 1.076 | 0.10 |
| 605_L | 622_F | 1.075 | 0.10 |
| 189_K | 209_K | 1.075 | 0.10 |
| 180_I | 206_E | 1.074 | 0.10 |
| 243_Y | 254_G | 1.074 | 0.10 |
| 507_A | 516_N | 1.073 | 0.10 |
| 493_S | 504_L | 1.072 | 0.10 |
| 497_D | 504_L | 1.072 | 0.10 |
| 466_S | 489_S | 1.072 | 0.10 |
| 336_D | 550_H | 1.071 | 0.10 |
| 208_E | 255_L | 1.070 | 0.10 |
| 468_N | 482_R | 1.070 | 0.10 |
| 194_I | 696_K | 1.070 | 0.10 |
| 448_L | 459_S | 1.070 | 0.10 |
| 512_N | 523_L | 1.070 | 0.10 |
| 23_D | 294_K | 1.068 | 0.10 |
| 935_E | 973_F | 1.067 | 0.10 |
| 229_K | 718_D | 1.067 | 0.10 |
| 40_S | 53_C | 1.067 | 0.10 |
| 698_N | 701_V | 1.066 | 0.10 |
| 415_K | 451_N | 1.064 | 0.09 |
| 622_F | 626_N | 1.064 | 0.09 |
| 606_H | 622_F | 1.063 | 0.09 |
| 639_T | 656_L | 1.063 | 0.09 |
| 409_S | 415_K | 1.062 | 0.09 |
| 167_D | 232_K | 1.062 | 0.09 |
| 916_K | 922_V | 1.060 | 0.09 |
| 410_V | 456_D | 1.060 | 0.09 |
| 579_L | 585_E | 1.059 | 0.09 |
| 276_K | 294_K | 1.057 | 0.09 |
| 463_T | 495_E | 1.057 | 0.09 |
| 617_L | 626_N | 1.057 | 0.09 |
| 506_L | 516_N | 1.057 | 0.09 |
| 125_T | 131_L | 1.056 | 0.09 |
| 138_G | 146_T | 1.056 | 0.09 |
| 185_R | 190_Q | 1.055 | 0.09 |
| 468_N | 489_S | 1.055 | 0.09 |
| 100_D | 499_L | 1.054 | 0.09 |
| 23_D | 47_T | 1.054 | 0.09 |
| 244_Y | 264_Y | 1.053 | 0.09 |
| 462_P | 499_L | 1.052 | 0.09 |
| 236_L | 572_K | 1.051 | 0.09 |
| 139_L | 359_A | 1.051 | 0.09 |
| 142_N | 314_M | 1.051 | 0.09 |
| 226_N | 231_K | 1.051 | 0.09 |
| 523_L | 534_S | 1.050 | 0.09 |
| 619_L | 947_T | 1.050 | 0.09 |
| 76_K | 79_K | 1.049 | 0.09 |
| 593_L | 604_A | 1.049 | 0.09 |
| 466_S | 474_C | 1.048 | 0.09 |
| 826_Q | 937_T | 1.048 | 0.09 |
| 125_T | 253_D | 1.046 | 0.09 |
| 608_A | 622_F | 1.046 | 0.09 |
| 602_E | 605_L | 1.045 | 0.09 |
| 102_F | 156_K | 1.045 | 0.09 |
| 251_F | 256_K | 1.045 | 0.09 |
| 463_T | 494_L | 1.045 | 0.09 |
| 232_K | 389_S | 1.045 | 0.09 |
| 512_N | 515_F | 1.044 | 0.09 |
| 128_L | 159_K | 1.043 | 0.09 |
| 926_Y | 934_D | 1.042 | 0.09 |
| 159_K | 934_D | 1.042 | 0.09 |
| 236_L | 577_L | 1.042 | 0.09 |
| 542_Y | 918_K | 1.041 | 0.09 |
| 524_P | 542_Y | 1.041 | 0.09 |
| 368_L | 469_L | 1.041 | 0.09 |
| 230_T | 718_D | 1.041 | 0.09 |
| 466_S | 493_S | 1.041 | 0.09 |
| 466_S | 497_D | 1.041 | 0.09 |
| 510_V | 580_I | 1.040 | 0.09 |
| 581_Q | 584_A | 1.040 | 0.09 |
| 73_K | 930_A | 1.039 | 0.09 |
| 137_Q | 341_V | 1.039 | 0.09 |
| 581_Q | 585_E | 1.038 | 0.09 |
| 141_H | 498_K | 1.037 | 0.09 |
| 445_V | 451_N | 1.037 | 0.09 |
| 65_D | 272_L | 1.036 | 0.09 |
| 25_I | 37_D | 1.036 | 0.09 |
| 476_E | 480_I | 1.036 | 0.09 |
| 336_D | 471_I | 1.034 | 0.09 |
| 341_V | 354_L | 1.033 | 0.09 |
| 327_K | 927_D | 1.033 | 0.09 |
| 365_P | 386_D | 1.032 | 0.09 |
| 951_D | 969_F | 1.031 | 0.09 |
| 283_K | 431_E | 1.031 | 0.09 |
| 605_L | 617_L | 1.031 | 0.09 |
| 462_P | 483_E | 1.031 | 0.09 |
| 22_P | 40_S | 1.031 | 0.09 |
| 697_F | 704_E | 1.030 | 0.09 |
| 103_G | 240_L | 1.029 | 0.09 |
| 344_R | 661_P | 1.026 | 0.09 |
| 87_D | 138_G | 1.026 | 0.09 |
| 151_L | 155_L | 1.025 | 0.09 |
| 457_C | 466_S | 1.025 | 0.09 |
| 166_F | 934_D | 1.025 | 0.09 |
| 450_G | 459_S | 1.025 | 0.09 |
| 380_E | 473_T | 1.024 | 0.09 |
| 468_N | 474_C | 1.024 | 0.09 |
| 639_T | 654_K | 1.024 | 0.09 |
| 334_K | 484_M | 1.023 | 0.09 |
| 50_L | 56_T | 1.022 | 0.09 |
| 932_N | 940_E | 1.022 | 0.09 |
| 273_Y | 484_M | 1.022 | 0.09 |
| 951_D | 955_W | 1.021 | 0.09 |
| 41_P | 54_R | 1.020 | 0.09 |
| 496_L | 507_A | 1.019 | 0.09 |
| 365_P | 394_Y | 1.018 | 0.09 |
| 387_L | 394_Y | 1.018 | 0.09 |
| 160_G | 232_K | 1.018 | 0.09 |
| 184_K | 202_E | 1.018 | 0.09 |
| 208_E | 603_T | 1.017 | 0.09 |
| 410_V | 418_A | 1.017 | 0.09 |
| 552_F | 723_D | 1.017 | 0.09 |
| 965_R | 974_V | 1.017 | 0.09 |
| 542_Y | 546_K | 1.017 | 0.09 |
| 638_N | 647_Y | 1.016 | 0.09 |
| 169_A | 941_G | 1.016 | 0.09 |
| 249_N | 252_Q | 1.016 | 0.09 |
| 39_N | 50_L | 1.016 | 0.09 |
| 30_F | 49_R | 1.015 | 0.09 |
| 969_F | 974_V | 1.015 | 0.09 |
| 91_N | 253_D | 1.014 | 0.09 |
| 931_D | 941_G | 1.014 | 0.09 |
| 34_T | 50_L | 1.013 | 0.09 |
| 402_Q | 723_D | 1.013 | 0.09 |
| 634_T | 673_A | 1.013 | 0.09 |
| 156_K | 826_Q | 1.013 | 0.09 |
| 50_L | 54_R | 1.012 | 0.09 |
| 26_S | 37_D | 1.010 | 0.09 |
| 167_D | 553_S | 1.010 | 0.09 |
| 111_N | 947_T | 1.010 | 0.09 |
| 113_D | 718_D | 1.009 | 0.09 |
| 166_F | 208_E | 1.009 | 0.09 |
| 439_K | 458_G | 1.009 | 0.09 |
| 265_I | 793_L | 1.009 | 0.09 |
| 180_I | 228_I | 1.009 | 0.09 |
| 368_L | 462_P | 1.009 | 0.09 |
| 698_N | 704_E | 1.009 | 0.09 |
| 335_S | 342_W | 1.008 | 0.09 |
| 95_Y | 640_V | 1.008 | 0.09 |
| 132_L | 244_Y | 1.008 | 0.09 |
| 343_Q | 358_H | 1.006 | 0.09 |
| 739_F | 742_S | 1.005 | 0.09 |
| 529_K | 536_M | 1.005 | 0.09 |
| 573_S | 904_T | 1.004 | 0.09 |
| 466_S | 504_L | 1.004 | 0.09 |
| 317_L | 484_M | 1.004 | 0.09 |
| 415_K | 423_F | 1.003 | 0.09 |
| 468_N | 472_L | 1.003 | 0.09 |
| 251_F | 254_G | 1.003 | 0.09 |
| 413_N | 418_A | 1.003 | 0.09 |
| 704_E | 717_S | 1.003 | 0.09 |
| 536_M | 547_Y | 1.003 | 0.09 |
| 347_C | 356_I | 1.001 | 0.08 |
| 692_A | 717_S | 1.001 | 0.08 |
| 359_A | 388_I | 1.001 | 0.08 |
| 403_D | 637_G | 1.001 | 0.08 |
| 34_T | 38_Y | 1.000 | 0.08 |
| 617_L | 620_V | 1.000 | 0.08 |
| 640_V | 659_S | 1.000 | 0.08 |
Prob = P(contact | scaled_score, seq/len).
Scaled Score = (raw_score/average(raw_scores)).
- Text file of contact predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
- Import to GREMLIN BETA - features includes ability to upload PDB and latest P(contact) calculation based on eLife 2015 fitting to PDB data.
GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled Score > 1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-position alignment confidence. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | M | Cov | P(%) | HHΔ | |
| 1dcqA | 1 | 0.2799 | 100 | 0.863 | Contact Map |
| 2b0oE | 4 | 0.2809 | 100 | 0.867 | Contact Map |
| 3lvqE | 1 | 0.3636 | 100 | 0.87 | Contact Map |
| 4h8sA | 4 | 0.3657 | 100 | 0.875 | Contact Map |
| 2q13A | 1 | 0.3616 | 100 | 0.881 | Contact Map |
| 4nswA | 2 | 0.3728 | 100 | 0.884 | Contact Map |
| 3jueA | 2 | 0.2533 | 100 | 0.885 | Contact Map |
| 2iqjA | 2 | 0.1256 | 100 | 0.925 | Contact Map |
| 2q12A | 1 | 0.2411 | 100 | 0.926 | Contact Map |
| 2crrA | 1 | 0.142 | 100 | 0.926 | Contact Map |
Cov = coverage of hit
P(%) = probability
Sequence Conservation (Image Generated using WebLogo v3)