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OPENSEQ.org
YGER - Uncharacterized lipoprotein YgeR
UniProt: Q46798 Sequence
 Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG13048
Length: 251 (231)
Sequences: 1077
Seq/Len: 4.66
YGER
Paralog alert: 0.43 [within 20: 0.00] - ratio of genomes with paralogs
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
42_Y 48_D 4.664 1.00
42_Y 57_T 3.654 1.00
152_A 215_M 2.881 1.00
195_N 213_A 2.798 1.00
158_I 195_N 2.715 1.00
190_T 229_I 2.613 1.00
149_D 224_R 2.607 1.00
215_M 223_V 2.497 1.00
182_I 212_I 2.453 1.00
152_A 156_T 2.374 1.00
149_D 226_H 2.353 1.00
169_V 198_M 2.335 1.00
196_D 214_T 2.294 1.00
132_G 150_I 2.205 1.00
128_W 150_I 2.137 1.00
153_P 156_T 2.13 1.00
130_T 215_M 2.119 1.00
154_R 196_D 2.094 1.00
221_A 224_R 2 1.00
133_K 151_S 1.911 1.00
217_S 220_A 1.892 1.00
197_T 214_T 1.842 1.00
126_W 188_Y 1.819 1.00
181_M 189_I 1.779 1.00
161_A 190_T 1.757 1.00
43_T 81_K 1.751 1.00
127_L 208_A 1.75 1.00
211_K 214_T 1.728 1.00
159_Y 211_K 1.712 0.99
236_I 241_Y 1.697 0.99
171_N 178_N 1.681 0.99
165_K 205_S 1.629 0.99
126_W 229_I 1.609 0.99
130_T 156_T 1.609 0.99
179_L 191_A 1.608 0.99
195_N 198_M 1.59 0.99
145_N 149_D 1.568 0.99
194_H 218_T 1.558 0.99
163_A 207_K 1.512 0.98
44_V 82_L 1.505 0.98
168_Y 179_L 1.481 0.98
44_V 47_G 1.443 0.98
207_K 210_Q 1.412 0.97
126_W 190_T 1.404 0.97
44_V 53_I 1.381 0.97
199_L 213_A 1.376 0.97
130_T 159_Y 1.364 0.96
162_G 208_A 1.35 0.96
23_L 26_C 1.326 0.95
48_D 57_T 1.318 0.95
237_D 240_R 1.315 0.95
160_A 209_G 1.309 0.95
199_L 214_T 1.306 0.95
28_G 34_T 1.304 0.95
179_L 230_R 1.286 0.94
145_N 224_R 1.261 0.94
188_Y 231_Y 1.251 0.93
168_Y 173_L 1.241 0.93
230_R 235_A 1.218 0.92
138_Y 235_A 1.194 0.91
128_W 243_P 1.176 0.90
49_T 52_R 1.166 0.90
179_L 195_N 1.163 0.89
135_I 145_N 1.159 0.89
17_L 21_L 1.148 0.89
219_D 224_R 1.14 0.88
184_H 190_T 1.138 0.88
41_V 81_K 1.116 0.87
30_K 33_D 1.104 0.86
181_M 191_A 1.096 0.85
169_V 187_D 1.08 0.84
18_S 34_T 1.061 0.83
15_M 20_G 1.052 0.82
148_I 239_L 1.048 0.82
154_R 223_V 1.045 0.81
201_N 204_Q 1.044 0.81
18_S 24_A 1.043 0.81
176_Y 193_A 1.038 0.81
42_Y 50_L 1.038 0.81
60_S 63_E 1.038 0.81
161_A 227_F 1.035 0.81
160_A 182_I 1.033 0.80
128_W 242_L 1.031 0.80
218_T 224_R 1.028 0.80
168_Y 191_A 1.026 0.80
168_Y 195_N 1.022 0.79
45_K 57_T 1.015 0.79
44_V 48_D 1.014 0.79
167_V 183_K 1.012 0.78
185_S 188_Y 1.01 0.78
29_S 36_T 1.01 0.78
172_Q 235_A 1.007 0.78
42_Y 53_I 1.005 0.78
17_L 20_G 1.002 0.77
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
2gu1A10.98411000.449Contact Map0.638
3sluA20.89241000.47Contact Map0.765
2hsiA20.93631000.515Contact Map0.801
1qwyA10.89241000.518Contact Map0.622
4bh5A40.54981000.522Contact Map0.783
3tufB10.65741000.553Contact Map0.643
3nyyA10.77691000.583Contact Map0.559
3it5A40.5021000.592Contact Map0.607
3csqA40.92431000.621Contact Map0.491
2djpA10.3068990.85Contact Map0.785
Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.
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