| UniProt: | P77736 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG13588 | ||
| Length: | 201 (189) | ||
| Sequences: | 20052 | ||
| Seq/Len: | 106.10 |
| YAHD
Paralog alert: 0.56 [within 20: 0.46] - ratio of genomes with paralogs |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 140_W | 174_D | 2.394 | 1.00 | |
| 55_V | 87_L | 2.37 | 1.00 | |
| 88_L | 120_I | 2.304 | 1.00 | |
| 121_V | 159_I | 2.286 | 1.00 | |
| 22_V | 54_C | 2.286 | 1.00 | |
| 160_V | 192_I | 2.224 | 1.00 | |
| 40_K | 69_D | 2.068 | 1.00 | |
| 73_L | 102_T | 2.015 | 1.00 | |
| 106_G | 136_N | 1.966 | 1.00 | |
| 18_D | 21_K | 1.903 | 1.00 | |
| 17_G | 51_Q | 1.9 | 1.00 | |
| 50_Q | 84_D | 1.802 | 1.00 | |
| 101_V | 134_Q | 1.686 | 1.00 | |
| 182_E | 185_R | 1.667 | 1.00 | |
| 24_T | 28_L | 1.654 | 1.00 | |
| 89_R | 123_E | 1.649 | 1.00 | |
| 135_T | 172_L | 1.606 | 1.00 | |
| 83_D | 117_H | 1.606 | 1.00 | |
| 57_A | 61_A | 1.584 | 1.00 | |
| 110_T | 142_P | 1.573 | 1.00 | |
| 19_I | 53_A | 1.569 | 1.00 | |
| 19_I | 57_A | 1.554 | 1.00 | |
| 144_L | 180_P | 1.553 | 1.00 | |
| 52_Y | 86_T | 1.525 | 1.00 | |
| 52_Y | 90_I | 1.524 | 1.00 | |
| 56_Q | 90_I | 1.518 | 1.00 | |
| 122_K | 162_L | 1.509 | 1.00 | |
| 23_K | 57_A | 1.498 | 1.00 | |
| 162_L | 166_H | 1.463 | 1.00 | |
| 178_K | 186_E | 1.458 | 1.00 | |
| 161_Q | 195_L | 1.455 | 1.00 | |
| 85_L | 119_S | 1.444 | 1.00 | |
| 90_I | 94_A | 1.435 | 1.00 | |
| 40_K | 48_L | 1.43 | 1.00 | |
| 116_G | 156_Q | 1.424 | 1.00 | |
| 157_Q | 195_L | 1.382 | 0.99 | |
| 68_Q | 100_C | 1.377 | 0.99 | |
| 35_C | 67_K | 1.369 | 0.99 | |
| 43_I | 55_V | 1.368 | 0.99 | |
| 44_T | 75_P | 1.366 | 0.99 | |
| 10_Y | 22_V | 1.357 | 0.99 | |
| 140_W | 148_V | 1.347 | 0.99 | |
| 185_R | 197_I | 1.347 | 0.99 | |
| 123_E | 128_T | 1.346 | 0.99 | |
| 109_L | 121_V | 1.34 | 0.99 | |
| 150_N | 189_F | 1.338 | 0.99 | |
| 21_K | 24_T | 1.337 | 0.99 | |
| 51_Q | 54_C | 1.336 | 0.99 | |
| 85_L | 123_E | 1.319 | 0.99 | |
| 76_F | 88_L | 1.312 | 0.99 | |
| 157_Q | 191_E | 1.31 | 0.99 | |
| 118_L | 162_L | 1.305 | 0.99 | |
| 11_L | 42_A | 1.302 | 0.99 | |
| 174_D | 178_K | 1.3 | 0.99 | |
| 118_L | 158_A | 1.288 | 0.99 | |
| 77_L | 108_G | 1.27 | 0.99 | |
| 85_L | 120_I | 1.248 | 0.99 | |
| 36_D | 40_K | 1.236 | 0.98 | |
| 59_I | 90_I | 1.227 | 0.98 | |
| 92_L | 123_E | 1.226 | 0.98 | |
| 73_L | 81_L | 1.226 | 0.98 | |
| 26_L | 57_A | 1.222 | 0.98 | |
| 185_R | 193_A | 1.217 | 0.98 | |
| 19_I | 54_C | 1.2 | 0.98 | |
| 110_T | 145_E | 1.188 | 0.98 | |
| 19_I | 23_K | 1.184 | 0.98 | |
| 9_D | 21_K | 1.184 | 0.98 | |
| 136_N | 140_W | 1.183 | 0.98 | |
| 125_L | 162_L | 1.18 | 0.98 | |
| 195_L | 199_A | 1.176 | 0.98 | |
| 164_L | 195_L | 1.169 | 0.97 | |
| 169_S | 172_L | 1.161 | 0.97 | |
| 7_P | 36_D | 1.153 | 0.97 | |
| 56_Q | 60_D | 1.146 | 0.97 | |
| 118_L | 122_K | 1.141 | 0.97 | |
| 190_E | 194_Q | 1.138 | 0.97 | |
| 106_G | 114_E | 1.132 | 0.97 | |
| 52_Y | 87_L | 1.13 | 0.97 | |
| 69_D | 73_L | 1.129 | 0.97 | |
| 113_C | 116_G | 1.126 | 0.97 | |
| 59_I | 65_I | 1.125 | 0.97 | |
| 125_L | 166_H | 1.124 | 0.97 | |
| 157_Q | 161_Q | 1.122 | 0.97 | |
| 85_L | 89_R | 1.116 | 0.96 | |
| 13_A | 22_V | 1.111 | 0.96 | |
| 194_Q | 198_A | 1.108 | 0.96 | |
| 46_A | 55_V | 1.105 | 0.96 | |
| 182_E | 197_I | 1.105 | 0.96 | |
| 47_S | 50_Q | 1.105 | 0.96 | |
| 102_T | 106_G | 1.104 | 0.96 | |
| 52_Y | 56_Q | 1.096 | 0.96 | |
| 125_L | 132_V | 1.09 | 0.96 | |
| 14_A | 17_G | 1.087 | 0.96 | |
| 149_L | 156_Q | 1.085 | 0.96 | |
| 117_H | 120_I | 1.081 | 0.95 | |
| 60_D | 94_A | 1.074 | 0.95 | |
| 161_Q | 165_E | 1.064 | 0.95 | |
| 147_I | 150_N | 1.058 | 0.95 | |
| 118_L | 159_I | 1.058 | 0.95 | |
| 156_Q | 159_I | 1.055 | 0.95 | |
| 174_D | 183_L | 1.054 | 0.95 | |
| 165_E | 199_A | 1.047 | 0.94 | |
| 164_L | 170_P | 1.046 | 0.94 | |
| 84_D | 87_L | 1.046 | 0.94 | |
| 8_A | 11_L | 1.036 | 0.94 | |
| 99_N | 130_I | 1.034 | 0.94 | |
| 181_L | 193_A | 1.034 | 0.94 | |
| 110_T | 144_L | 1.029 | 0.94 | |
| 127_H | 166_H | 1.026 | 0.94 | |
| 157_Q | 192_I | 1.023 | 0.93 | |
| 23_K | 27_A | 1.018 | 0.93 | |
| 80_C | 83_D | 1.015 | 0.93 | |
| 77_L | 111_P | 1.014 | 0.93 | |
| 143_L | 160_V | 1.014 | 0.93 | |
| 27_A | 61_A | 1.012 | 0.93 | |
| 89_R | 93_P | 1.01 | 0.93 | |
| 79_S | 88_L | 1.01 | 0.93 | |
| 14_A | 54_C | 1.01 | 0.93 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 1oy3D | 1 | 0.9701 | 100 | 0.046 | Contact Map | 0.816 |
| 3ljnA | 1 | 0.9701 | 100 | 0.05 | Contact Map | 0.646 |
| 3utmA | 2 | 0.9701 | 100 | 0.066 | Contact Map | 0.717 |
| 2etbA | 1 | 0.9751 | 100 | 0.071 | Contact Map | 0.668 |
| 1yyhA | 2 | 0.9701 | 100 | 0.072 | Contact Map | 0.763 |
| 2rfaA | 1 | 0.9552 | 100 | 0.073 | Contact Map | 0.652 |
| 1n11A | 1 | 0.9701 | 100 | 0.075 | Contact Map | 0.788 |
| 2pnnA | 1 | 0.9701 | 100 | 0.078 | Contact Map | 0.608 |
| 2xaiA | 2 | 0.9453 | 100 | 0.084 | Contact Map | 0.736 |
| 2f8yA | 2 | 0.9701 | 100 | 0.088 | Contact Map | 0.863 |
Sequence Conservation (Image Generated using WebLogo v3)