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OPENSEQ.org
YBBP - Uncharacterized ABC transporter permease YbbP
UniProt: P77504 Sequence
 Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG13263
Length: 804 (802)
Sequences: 2290
Seq/Len: 2.86
YBBP
Paralog alert: 0.28 [within 20: 0.03] - ratio of genomes with paralogs
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
574_S 606_S 3.928 1.00
585_V 604_V 3.841 1.00
119_L 125_S 3.765 1.00
126_V 176_M 3.269 1.00
118_G 121_P 3.181 1.00
590_T 601_R 3.009 1.00
270_R 294_Q 2.927 1.00
143_T 152_R 2.89 1.00
580_A 607_L 2.872 1.00
126_V 174_L 2.848 1.00
590_T 603_K 2.82 1.00
119_L 154_A 2.806 1.00
128_L 174_L 2.771 1.00
64_P 67_W 2.751 1.00
143_T 150_T 2.67 1.00
577_E 581_K 2.647 1.00
19_W 302_S 2.618 1.00
138_L 153_I 2.612 1.00
125_S 154_A 2.504 1.00
130_P 134_A 2.493 1.00
285_A 289_K 2.438 1.00
739_S 743_A 2.399 1.00
575_M 607_L 2.394 1.00
575_M 604_V 2.375 1.00
707_R 731_E 2.339 1.00
577_E 609_K 2.296 1.00
128_L 133_M 2.265 1.00
133_M 156_E 2.265 1.00
592_T 601_R 2.246 1.00
127_L 155_G 2.238 1.00
572_E 605_T 2.235 1.00
575_M 585_V 2.203 1.00
353_L 357_R 2.187 1.00
69_E 72_Q 2.151 1.00
139_K 586_A 2.151 1.00
127_L 157_V 2.139 1.00
587_L 607_L 2.139 1.00
424_M 428_V 2.134 1.00
274_V 291_I 2.126 1.00
712_V 716_T 2.119 1.00
357_R 361_A 2.087 1.00
573_V 591_V 2.063 1.00
128_L 153_I 2.038 1.00
130_P 156_E 2.004 1.00
784_F 788_L 1.959 0.99
30_L 340_A 1.956 0.99
278_K 715_R 1.918 0.99
445_R 731_E 1.905 0.99
280_L 717_L 1.877 0.99
303_A 344_M 1.875 0.99
575_M 579_L 1.859 0.99
306_G 310_G 1.844 0.99
303_A 341_L 1.823 0.99
23_S 305_T 1.788 0.99
442_A 730_C 1.782 0.99
707_R 710_E 1.772 0.99
560_P 609_K 1.763 0.99
128_L 144_I 1.759 0.99
506_K 510_A 1.731 0.98
574_S 608_R 1.724 0.98
70_E 73_K 1.721 0.98
575_M 580_A 1.717 0.98
71_A 79_G 1.714 0.98
312_L 316_V 1.713 0.98
579_L 583_L 1.699 0.98
779_L 783_L 1.692 0.98
282_A 719_A 1.683 0.98
587_L 606_S 1.678 0.98
788_L 792_L 1.677 0.98
587_L 605_T 1.672 0.98
204_N 209_Y 1.671 0.98
139_K 142_D 1.659 0.98
573_V 623_F 1.656 0.98
25_A 255_A 1.645 0.98
121_P 125_S 1.631 0.97
53_G 56_A 1.627 0.97
283_G 286_Q 1.602 0.97
586_A 589_D 1.6 0.97
19_W 23_S 1.59 0.97
126_V 144_I 1.585 0.97
789_G 792_L 1.583 0.97
460_F 739_S 1.582 0.97
145_D 150_T 1.58 0.97
278_K 284_R 1.575 0.97
130_P 158_I 1.569 0.97
561_I 606_S 1.566 0.97
736_G 740_G 1.562 0.96
140_T 154_A 1.562 0.96
262_A 702_V 1.554 0.96
259_V 462_L 1.543 0.96
573_V 602_A 1.541 0.96
284_R 360_L 1.54 0.96
464_F 743_A 1.525 0.96
789_G 793_V 1.519 0.96
70_E 74_R 1.508 0.95
128_L 132_L 1.505 0.95
722_K 726_T 1.498 0.95
140_T 153_I 1.497 0.95
460_F 464_F 1.494 0.95
786_G 790_A 1.47 0.95
572_E 603_K 1.47 0.95
391_V 394_L 1.468 0.94
595_G 598_Q 1.46 0.94
448_R 731_E 1.451 0.94
133_M 140_T 1.44 0.94
504_P 507_A 1.439 0.94
26_V 344_M 1.432 0.93
71_A 76_L 1.431 0.93
799_F 802_F 1.431 0.93
593_F 602_A 1.423 0.93
767_W 771_I 1.423 0.93
255_A 258_A 1.418 0.93
210_E 214_L 1.413 0.93
68_L 72_Q 1.399 0.92
5_W 9_E 1.398 0.92
79_G 196_R 1.395 0.92
711_L 728_L 1.386 0.92
452_S 706_Q 1.367 0.91
205_Q 208_G 1.367 0.91
283_G 720_G 1.364 0.91
133_M 153_I 1.358 0.91
261_V 359_L 1.354 0.91
277_L 734_M 1.353 0.91
668_K 672_Q 1.35 0.91
419_G 422_G 1.348 0.90
795_G 798_L 1.341 0.90
726_T 730_C 1.34 0.90
76_L 79_G 1.339 0.90
389_V 394_L 1.338 0.90
464_F 689_T 1.331 0.90
261_V 265_H 1.327 0.90
299_L 348_S 1.325 0.89
473_L 754_L 1.324 0.89
307_G 341_L 1.316 0.89
37_D 41_K 1.307 0.89
295_W 356_Y 1.3 0.88
265_H 698_A 1.295 0.88
584_N 607_L 1.293 0.88
578_G 581_K 1.293 0.88
304_V 341_L 1.29 0.88
790_A 794_K 1.29 0.88
69_E 73_K 1.286 0.87
38_R 359_L 1.284 0.87
777_G 781_L 1.284 0.87
127_L 154_A 1.279 0.87
30_L 310_G 1.278 0.87
708_H 716_T 1.278 0.87
771_I 782_S 1.277 0.87
445_R 710_E 1.277 0.87
388_V 391_V 1.276 0.87
382_Y 385_I 1.272 0.87
118_G 125_S 1.27 0.87
702_V 706_Q 1.268 0.86
427_N 431_R 1.26 0.86
274_V 287_L 1.247 0.85
298_V 410_G 1.241 0.85
265_H 695_L 1.239 0.85
662_D 665_A 1.237 0.85
140_T 156_E 1.236 0.85
66_A 285_A 1.231 0.84
709_Q 713_V 1.225 0.84
571_D 603_K 1.22 0.83
151_L 174_L 1.219 0.83
664_G 668_K 1.214 0.83
592_T 599_E 1.206 0.83
355_P 695_L 1.199 0.82
9_E 270_R 1.197 0.82
19_W 301_L 1.196 0.82
387_S 391_V 1.193 0.82
459_A 695_L 1.193 0.82
575_M 583_L 1.192 0.82
270_R 291_I 1.191 0.81
300_T 304_V 1.19 0.81
696_L 719_A 1.188 0.81
604_V 607_L 1.187 0.81
146_V 151_L 1.187 0.81
265_H 706_Q 1.186 0.81
565_N 605_T 1.185 0.81
22_L 298_V 1.181 0.81
594_M 599_E 1.176 0.80
585_V 589_D 1.173 0.80
255_A 348_S 1.173 0.80
261_V 692_G 1.173 0.80
3_A 7_W 1.169 0.80
444_S 447_L 1.167 0.80
312_L 315_N 1.166 0.80
687_L 696_L 1.166 0.80
573_V 621_F 1.164 0.79
295_W 352_G 1.162 0.79
124_G 180_D 1.16 0.79
775_C 779_L 1.158 0.79
355_P 359_L 1.156 0.79
270_R 273_L 1.153 0.78
29_V 248_A 1.15 0.78
369_R 466_L 1.147 0.78
409_A 412_V 1.146 0.78
259_V 271_Y 1.144 0.78
355_P 460_F 1.143 0.78
127_L 175_M 1.143 0.78
18_V 252_L 1.138 0.77
261_V 698_A 1.137 0.77
277_L 714_W 1.136 0.77
117_P 121_P 1.132 0.77
708_H 712_V 1.129 0.76
307_G 311_L 1.127 0.76
753_V 757_K 1.124 0.76
144_I 151_L 1.124 0.76
128_L 425_L 1.123 0.76
576_E 610_V 1.123 0.76
177_N 180_D 1.122 0.76
713_V 717_L 1.122 0.76
429_L 687_L 1.121 0.76
341_L 651_L 1.12 0.76
406_A 409_A 1.119 0.75
261_V 445_R 1.117 0.75
389_V 396_G 1.115 0.75
564_G 587_L 1.115 0.75
436_S 439_L 1.113 0.75
16_L 52_A 1.112 0.75
698_A 747_A 1.111 0.75
503_A 507_A 1.111 0.75
31_A 358_L 1.108 0.74
800_R 803_A 1.107 0.74
272_D 276_I 1.106 0.74
78_V 690_A 1.105 0.74
100_K 160_E 1.102 0.74
364_P 367_V 1.1 0.74
273_L 276_I 1.099 0.74
394_L 406_A 1.099 0.74
710_E 715_R 1.099 0.74
126_V 153_I 1.093 0.73
9_E 273_L 1.088 0.73
395_A 398_M 1.087 0.72
303_A 702_V 1.087 0.72
472_V 751_L 1.086 0.72
308_A 312_L 1.084 0.72
699_Q 704_M 1.084 0.72
790_A 796_K 1.083 0.72
741_L 745_I 1.082 0.72
703_G 731_E 1.081 0.72
423_W 427_N 1.079 0.72
744_A 747_A 1.079 0.72
388_V 425_L 1.078 0.72
23_S 27_A 1.078 0.72
413_V 416_L 1.076 0.71
304_V 308_A 1.076 0.71
514_I 530_I 1.076 0.71
139_K 150_T 1.076 0.71
182_D 211_K 1.075 0.71
359_L 699_Q 1.075 0.71
14_S 463_S 1.074 0.71
41_K 44_S 1.074 0.71
722_K 775_C 1.073 0.71
716_T 788_L 1.072 0.71
21_A 258_A 1.07 0.71
24_L 364_P 1.069 0.71
84_F 99_V 1.068 0.71
440_R 448_R 1.064 0.70
792_L 798_L 1.063 0.70
481_W 484_Q 1.063 0.70
589_D 604_V 1.063 0.70
54_D 161_P 1.062 0.70
19_W 340_A 1.059 0.70
122_Q 125_S 1.058 0.70
120_K 127_L 1.057 0.69
280_L 362_T 1.056 0.69
368_L 747_A 1.056 0.69
459_A 463_S 1.055 0.69
73_K 289_K 1.055 0.69
465_M 750_A 1.055 0.69
711_L 724_L 1.054 0.69
743_A 747_A 1.054 0.69
283_G 289_K 1.053 0.69
792_L 797_A 1.051 0.69
121_P 154_A 1.051 0.69
57_L 458_S 1.049 0.69
456_Q 710_E 1.049 0.69
288_R 357_R 1.048 0.68
260_A 351_V 1.048 0.68
586_A 603_K 1.047 0.68
766_D 769_L 1.046 0.68
691_C 695_L 1.045 0.68
356_Y 359_L 1.045 0.68
395_A 404_L 1.044 0.68
291_I 294_Q 1.043 0.68
386_V 394_L 1.042 0.68
452_S 710_E 1.04 0.68
453_T 735_L 1.04 0.68
302_S 306_G 1.039 0.68
788_L 793_V 1.038 0.67
259_V 451_W 1.035 0.67
388_V 435_K 1.034 0.67
14_S 265_H 1.034 0.67
364_P 368_L 1.034 0.67
362_T 367_V 1.033 0.67
291_I 695_L 1.03 0.67
20_L 503_A 1.028 0.66
135_L 252_L 1.028 0.66
55_R 210_E 1.027 0.66
416_L 420_V 1.025 0.66
302_S 739_S 1.024 0.66
441_L 445_R 1.023 0.66
202_N 205_Q 1.023 0.66
208_G 304_V 1.022 0.66
25_A 344_M 1.022 0.66
295_W 348_S 1.021 0.66
25_A 735_L 1.021 0.66
462_L 674_L 1.021 0.66
404_L 798_L 1.021 0.66
267_C 367_V 1.021 0.66
386_V 389_V 1.021 0.66
408_L 415_A 1.02 0.65
66_A 69_E 1.019 0.65
683_V 704_M 1.017 0.65
299_L 303_A 1.017 0.65
390_V 399_G 1.017 0.65
6_F 9_E 1.016 0.65
26_V 306_G 1.015 0.65
492_Y 495_I 1.012 0.65
279_T 711_L 1.01 0.64
564_G 719_A 1.01 0.64
445_R 698_A 1.009 0.64
445_R 448_R 1.009 0.64
265_H 294_Q 1.008 0.64
32_L 467_L 1.006 0.64
692_G 696_L 1.006 0.64
261_V 695_L 1.006 0.64
251_T 293_G 1.005 0.64
150_T 350_L 1.004 0.64
66_A 78_V 1.002 0.63
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
3ftjA10.243898.80.912Contact Map0.758
3is6A20.248898.30.927Contact Map0.694
4eneA20.110717.10.978Contact Map0.301
2l66A20.065915.60.978Contact Map0.371
2pn0A40.161713.10.979Contact Map0.484
3bmbA20.14811.90.979Contact Map0.348
3nd0A20.1244110.979Contact Map0.24
1yfbA20.07349.30.98Contact Map0.519
1grjA10.16549.20.98Contact Map0.515
2p4vA60.16797.10.981Contact Map0.421
Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.
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