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OPENSEQ.org
YGAZ - Inner membrane protein YgaZ
UniProt: P76630 Sequence
 Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG13528
Length: 245 (221)
Sequences: 1249
Seq/Len: 5.65
YGAZ
Paralog alert: 0.17 [within 20: 0.00] - ratio of genomes with paralogs
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
21_D 140_W 3.043 1.00
46_S 49_E 3.003 1.00
51_V 157_V 2.845 1.00
53_F 66_I 2.604 1.00
18_G 143_G 2.489 1.00
15_F 143_G 2.381 1.00
55_C 153_V 2.378 1.00
59_A 87_D 2.368 1.00
116_G 145_A 2.246 1.00
33_A 155_G 2.165 1.00
59_A 90_H 2.112 1.00
96_S 122_F 2.09 1.00
40_A 50_S 2.079 1.00
65_V 86_M 2.077 1.00
36_F 63_Q 2.054 1.00
16_M 20_K 1.991 1.00
47_P 160_A 1.885 1.00
59_A 83_V 1.831 1.00
15_F 146_F 1.749 1.00
58_Y 118_T 1.722 1.00
149_W 153_V 1.716 1.00
54_S 156_T 1.694 1.00
29_Y 148_S 1.689 1.00
52_F 56_I 1.669 1.00
29_Y 118_T 1.659 1.00
69_M 74_S 1.653 1.00
51_V 153_V 1.643 1.00
53_F 57_I 1.63 0.99
65_V 82_T 1.564 0.99
121_V 148_S 1.495 0.99
115_F 149_W 1.473 0.99
212_V 223_A 1.434 0.98
25_I 148_S 1.432 0.98
41_T 160_A 1.403 0.98
90_H 117_L 1.392 0.98
111_A 149_W 1.368 0.98
32_V 148_S 1.363 0.97
59_A 62_S 1.361 0.97
58_Y 90_H 1.306 0.97
43_L 67_T 1.301 0.96
187_S 191_A 1.278 0.96
157_V 161_F 1.268 0.96
108_S 138_E 1.257 0.95
221_I 224_G 1.25 0.95
120_E 183_A 1.249 0.95
67_T 71_A 1.246 0.95
224_G 228_G 1.241 0.95
93_Y 185_F 1.234 0.95
204_A 223_A 1.229 0.95
204_A 231_T 1.218 0.94
93_Y 179_F 1.216 0.94
12_S 16_M 1.211 0.94
29_Y 32_V 1.21 0.94
36_F 64_F 1.205 0.94
28_S 148_S 1.201 0.94
63_Q 156_T 1.2 0.94
22_S 144_I 1.197 0.94
108_S 142_I 1.194 0.93
34_F 158_I 1.186 0.93
116_G 149_W 1.175 0.93
36_F 156_T 1.173 0.93
97_L 117_L 1.172 0.93
33_A 178_G 1.171 0.93
54_S 63_Q 1.168 0.92
83_V 180_M 1.151 0.92
216_S 220_A 1.151 0.92
22_S 147_S 1.146 0.92
29_Y 184_L 1.145 0.91
106_Q 110_T 1.14 0.91
63_Q 118_T 1.129 0.91
90_H 120_E 1.129 0.91
17_E 21_D 1.127 0.91
75_S 78_I 1.116 0.90
151_S 155_G 1.111 0.90
45_F 53_F 1.11 0.90
135_R 227_C 1.106 0.90
22_S 151_S 1.101 0.89
88_V 91_V 1.1 0.89
26_V 151_S 1.095 0.89
57_I 62_S 1.072 0.87
121_V 144_I 1.07 0.87
69_M 82_T 1.061 0.87
58_Y 149_W 1.06 0.87
64_F 181_L 1.057 0.86
50_S 160_A 1.056 0.86
36_F 40_A 1.054 0.86
58_Y 153_V 1.047 0.86
231_T 234_I 1.046 0.86
164_S 186_M 1.046 0.86
23_L 27_I 1.044 0.86
41_T 51_V 1.043 0.85
93_Y 229_C 1.042 0.85
17_E 128_K 1.041 0.85
25_I 86_M 1.037 0.85
75_S 79_A 1.029 0.84
66_I 83_V 1.028 0.84
15_F 147_S 1.026 0.84
79_A 83_V 1.026 0.84
28_S 124_A 1.021 0.84
39_N 181_L 1.017 0.83
15_F 18_G 1.01 0.83
76_L 80_A 1.009 0.83
120_E 188_F 1.005 0.82
39_N 63_Q 1.004 0.82
30_I 155_G 1.002 0.82
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results:
PDB Chains Cov P(%) HHΔ   Acc
2ls4A10.09398.70.959Contact Map0.009
4bwzA10.94293.80.966Contact Map0.11
2kluA10.17142.20.97Contact Map0.478
3l1lA10.836720.97Contact Map0.205
2nr9A10.69820.97Contact Map0.173
3o7qA10.50220.971Contact Map0.179
1jb0I10.1511.90.971Contact Map0
3pjzA20.24491.50.972Contact Map0.621
2l8sA10.18371.50.973Contact Map0.489
3j01B10.21221.50.973Contact Map0.148
Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.
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