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OPENSEQ.org
MLAA - Probable phospholipid-binding lipoprotein MlaA
UniProt: P76506 Sequence
 Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG14276
Length: 251 (228)
Sequences: 662
Seq/Len: 2.90
MLAA
Paralog alert: 0.10 [within 20: 0.00] - ratio of genomes with paralogs
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
35_F 39_M 3.731 1.00
131_H 135_S 2.983 1.00
81_P 103_F 2.506 1.00
48_D 193_R 2.483 1.00
157_T 218_F 2.478 1.00
70_G 73_N 2.412 1.00
40_Y 209_P 2.222 1.00
53_R 57_V 2.218 1.00
86_N 133_F 2.177 1.00
84_M 100_F 2.144 1.00
88_F 96_G 2.138 1.00
65_Q 68_R 2.127 1.00
63_V 67_A 2.124 1.00
91_G 139_H 2.11 1.00
220_R 224_I 2.09 1.00
142_V 145_G 2.085 1.00
111_M 115_I 1.906 0.99
80_E 103_F 1.844 0.99
134_G 160_D 1.771 0.99
92_D 227_G 1.751 0.99
83_V 87_Y 1.735 0.98
92_D 131_H 1.724 0.98
132_R 135_S 1.717 0.98
56_A 197_L 1.687 0.98
160_D 221_H 1.685 0.98
42_F 47_L 1.677 0.98
132_R 221_H 1.658 0.98
131_H 227_G 1.653 0.98
47_L 152_F 1.653 0.98
45_N 209_P 1.633 0.98
43_N 149_Q 1.628 0.97
33_E 37_R 1.622 0.97
133_F 167_D 1.621 0.97
76_G 128_T 1.618 0.97
102_R 116_D 1.598 0.97
40_Y 149_Q 1.598 0.97
32_L 146_P 1.597 0.97
58_A 61_D 1.532 0.96
77_N 107_T 1.513 0.96
133_F 166_A 1.504 0.95
144_Y 222_D 1.498 0.95
108_I 112_G 1.457 0.94
87_Y 129_E 1.45 0.94
137_L 142_V 1.425 0.93
53_R 200_D 1.418 0.93
226_N 229_E 1.413 0.93
34_G 39_M 1.408 0.93
135_S 225_A 1.401 0.93
87_Y 99_H 1.398 0.93
68_R 194_A 1.398 0.93
46_V 50_Y 1.365 0.91
131_H 225_A 1.358 0.91
93_P 96_G 1.35 0.91
81_P 209_P 1.34 0.90
91_G 140_Y 1.335 0.90
86_N 167_D 1.3 0.88
66_P 70_G 1.29 0.88
60_R 68_R 1.289 0.88
50_Y 58_A 1.273 0.87
86_N 136_T 1.254 0.86
84_M 96_G 1.241 0.85
92_D 228_G 1.225 0.84
85_V 170_Y 1.214 0.83
83_V 129_E 1.212 0.83
55_V 190_I 1.192 0.82
87_Y 95_Q 1.169 0.80
109_L 112_G 1.169 0.80
80_E 99_H 1.164 0.80
39_M 43_N 1.149 0.78
142_V 146_P 1.145 0.78
85_V 166_A 1.137 0.77
138_G 144_Y 1.134 0.77
212_M 216_A 1.134 0.77
67_A 112_G 1.13 0.77
92_D 139_H 1.129 0.77
135_S 139_H 1.127 0.77
202_L 205_Q 1.127 0.77
35_F 38_T 1.121 0.76
60_R 198_D 1.121 0.76
216_A 219_Q 1.118 0.76
105_L 121_A 1.113 0.75
175_W 178_W 1.098 0.74
150_L 156_F 1.094 0.74
35_F 148_V 1.09 0.73
211_I 215_E 1.08 0.72
58_A 62_Y 1.079 0.72
133_F 137_L 1.078 0.72
162_G 165_M 1.075 0.72
181_S 184_K 1.074 0.72
133_F 136_T 1.064 0.71
57_V 61_D 1.06 0.70
92_D 135_S 1.051 0.69
101_T 104_F 1.048 0.69
33_E 147_Y 1.043 0.68
202_L 212_M 1.038 0.68
203_L 213_V 1.03 0.67
83_V 99_H 1.027 0.67
80_E 83_V 1.026 0.67
65_Q 69_N 1.025 0.66
55_V 192_T 1.022 0.66
46_V 49_P 1.022 0.66
80_E 84_M 1.02 0.66
185_W 189_G 1.019 0.66
102_R 118_A 1.018 0.66
41_N 114_F 1.017 0.66
99_H 224_I 1.016 0.65
232_P 243_D 1.014 0.65
232_P 236_P 1.012 0.65
82_A 170_Y 1.011 0.65
97_M 101_T 1.007 0.64
70_G 114_F 1.006 0.64
72_S 195_Q 1.003 0.64
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results:
PDB Chains Cov P(%) HHΔ   Acc
3zbiC140.187339.50.959Contact Map0
3s88J10.541811.30.968Contact Map0.003
1wjnA10.30683.90.975Contact Map0.168
3sriB10.11552.90.976Contact Map0.087
3zpmA10.34662.90.976Contact Map0.317
3b1lX10.29482.60.977Contact Map0.503
2jshA10.09562.60.977Contact Map0.412
2fyuK10.17532.50.977Contact Map0.216
4aqnA20.47412.40.977Contact Map0.579
2ju0B10.07971.80.979Contact Map
Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.
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