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OPENSEQ.org
FLGA - Flagella basal body P-ring formation protein FlgA
UniProt: P75933 Sequence
 Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG20263
Length: 219 (211)
Sequences: 488
Seq/Len: 2.31
FLGA
Paralog alert: 0.16 [within 20: 0.00] - ratio of genomes with paralogs
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
104_I 141_S 3.81 1.00
57_C 80_C 3.026 1.00
100_A 145_L 2.871 1.00
98_V 117_L 2.176 1.00
63_S 77_L 2.083 1.00
97_Y 120_G 2.045 0.99
130_V 136_L 1.993 0.99
161_R 191_V 1.903 0.99
141_S 145_L 1.71 0.97
102_M 108_G 1.677 0.97
42_E 119_R 1.665 0.97
189_A 195_A 1.665 0.97
211_A 214_N 1.644 0.96
15_F 19_S 1.509 0.93
186_L 204_V 1.443 0.91
170_V 199_M 1.427 0.90
32_F 89_V 1.422 0.90
102_M 114_N 1.421 0.90
170_V 207_G 1.409 0.90
132_D 135_Q 1.397 0.89
197_V 215_I 1.391 0.89
136_L 156_F 1.369 0.88
207_G 215_I 1.364 0.88
162_V 209_V 1.344 0.87
181_A 199_M 1.336 0.86
161_R 209_V 1.333 0.86
10_I 13_I 1.331 0.86
29_H 33_S 1.33 0.86
189_A 209_V 1.327 0.86
80_C 83_D 1.327 0.86
93_A 198_R 1.324 0.85
57_C 83_D 1.321 0.85
104_I 110_L 1.309 0.85
120_G 177_F 1.29 0.83
97_Y 150_P 1.266 0.82
28_L 75_N 1.259 0.81
12_A 15_F 1.255 0.81
11_I 15_F 1.25 0.81
62_L 78_A 1.237 0.80
17_P 20_T 1.225 0.79
10_I 16_S 1.225 0.79
11_I 19_S 1.21 0.78
10_I 15_F 1.204 0.77
43_V 132_D 1.204 0.77
9_A 13_I 1.203 0.77
111_E 114_N 1.199 0.77
95_G 122_L 1.198 0.77
76_V 86_Y 1.193 0.76
30_N 110_L 1.189 0.76
100_A 104_I 1.179 0.75
174_G 177_F 1.171 0.74
160_W 163_K 1.168 0.74
28_L 62_L 1.161 0.73
210_D 216_L 1.157 0.73
33_S 45_V 1.156 0.73
170_V 205_V 1.153 0.73
143_R 185_A 1.149 0.72
106_R 187_N 1.144 0.72
9_A 12_A 1.141 0.72
47_I 136_L 1.136 0.71
170_V 183_G 1.136 0.71
90_N 130_V 1.131 0.71
15_F 18_L 1.121 0.70
110_L 141_S 1.118 0.69
10_I 20_T 1.115 0.69
136_L 141_S 1.114 0.69
72_G 91_V 1.113 0.69
98_V 115_V 1.109 0.68
101_A 116_K 1.106 0.68
57_C 172_A 1.103 0.68
93_A 122_L 1.098 0.67
68_S 113_G 1.093 0.67
16_S 20_T 1.089 0.66
112_A 137_V 1.087 0.66
12_A 18_L 1.085 0.66
11_I 18_L 1.084 0.66
19_S 22_S 1.084 0.66
87_L 110_L 1.081 0.66
12_A 19_S 1.081 0.66
61_L 79_R 1.078 0.65
114_N 137_V 1.077 0.65
13_I 22_S 1.071 0.64
15_F 20_T 1.07 0.64
191_V 197_V 1.065 0.64
88_Q 203_Q 1.065 0.64
80_C 172_A 1.064 0.64
10_I 18_L 1.06 0.63
18_L 21_A 1.06 0.63
186_L 198_R 1.054 0.63
148_D 176_G 1.051 0.62
105_A 108_G 1.05 0.62
13_I 19_S 1.049 0.62
87_L 145_L 1.044 0.62
14_L 21_A 1.043 0.61
13_I 16_S 1.042 0.61
146_S 189_A 1.041 0.61
149_Q 165_G 1.04 0.61
9_A 15_F 1.04 0.61
12_A 17_P 1.034 0.60
13_I 18_L 1.032 0.60
88_Q 91_V 1.03 0.60
161_R 189_A 1.03 0.60
9_A 16_S 1.029 0.60
118_K 141_S 1.029 0.60
138_D 192_A 1.028 0.60
173_S 178_S 1.024 0.59
205_V 211_A 1.019 0.59
27_Q 62_L 1.018 0.59
32_F 179_A 1.017 0.59
106_R 156_F 1.015 0.58
132_D 193_Q 1.01 0.58
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
3teeA10.90411000.238Contact Map0.602
3frnA10.97721000.342Contact Map0.519
1msiA10.319698.50.83Contact Map0.749
1opsA10.2922980.852Contact Map0.737
1ucsA10.292297.90.853Contact Map0.765
1wvoA10.360797.40.869Contact Map0.729
2wqpA10.602791.80.909Contact Map0.729
1vliA10.7032820.922Contact Map0.683
1c89A10.497778.60.925Contact Map0.538
3g8rA20.675868.50.93Contact Map0.633
Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.
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